| Knockdown of FBLN2 suppresses TGF-beta1-induced MRC-5 cell migration and fibrosis by downregulating VTN. | Knockdown of FBLN2 suppresses TGF-β1-induced MRC-5 cell migration and fibrosis by downregulating VTN.
Zhang Y, Zhang W, Zhang R, Xia Y. | 03/30/2023 |
| Vitronectin and Its Interaction with PAI-1 Suggests a Functional Link to Vascular Changes in AMD Pathobiology. | Vitronectin and Its Interaction with PAI-1 Suggests a Functional Link to Vascular Changes in AMD Pathobiology.
Biasella F, Strunz T, Kiel C, On Behalf Of The International Amd Genomics Consortium Iamdgc, Weber BHF, Friedrich U., Free PMC Article | 06/18/2022 |
| Vitronectin, a Novel Urinary Proteomic Biomarker, Promotes Cell Pyroptosis in Juvenile Systemic Lupus Erythematosus. | Vitronectin, a Novel Urinary Proteomic Biomarker, Promotes Cell Pyroptosis in Juvenile Systemic Lupus Erythematosus.
Zhang S, Pan W, Wang H, Zhi C, Lin Y, Wu P, Ren Q, Wei P, Chen R, Li F, Xie Y, Wong CK, Tang H, Cai Z, Xu W, Zeng H., Free PMC Article | 05/14/2022 |
| Correlations between vitronectin, miR-520, and miR-34 in patients with stenosis of coronary arteries. | Correlations between vitronectin, miR-520, and miR-34 in patients with stenosis of coronary arteries.
Ghasempour G, Shaikhnia F, Soleimani AA, Rahimi B, Najafi M. | 03/5/2022 |
| Laminin-511 and recombinant vitronectin supplementation enables human pluripotent stem cell culture and differentiation on conventional tissue culture polystyrene surfaces in xeno-free conditions. | Laminin-511 and recombinant vitronectin supplementation enables human pluripotent stem cell culture and differentiation on conventional tissue culture polystyrene surfaces in xeno-free conditions.
Liu YC, Ban LK, Lee HH, Lee HT, Chang YT, Lin YT, Su HY, Hsu ST, Higuchi A. | 02/19/2022 |
| Complement Inhibitors Vitronectin and Clusterin Are Recruited from Human Serum to the Surface of Coronavirus OC43-Infected Lung Cells through Antibody-Dependent Mechanisms. | Complement Inhibitors Vitronectin and Clusterin Are Recruited from Human Serum to the Surface of Coronavirus OC43-Infected Lung Cells through Antibody-Dependent Mechanisms.
Fox CR, Parks GD., Free PMC Article | 02/5/2022 |
| Vitronectin binding protein, BOM1093, confers serum resistance on Borrelia miyamotoi. | Vitronectin binding protein, BOM1093, confers serum resistance on Borrelia miyamotoi.
Sato K, Kumagai Y, Sekizuka T, Kuroda M, Hayashi T, Takano A, Gaowa, Taylor KR, Ohnishi M, Kawabata H., Free PMC Article | 12/11/2021 |
| Regulatory properties of vitronectin and its glycosylation in collagen fibril formation and collagen-degrading enzyme cathepsin K activity. | Regulatory properties of vitronectin and its glycosylation in collagen fibril formation and collagen-degrading enzyme cathepsin K activity.
Date K, Sakagami H, Yura K., Free PMC Article | 10/23/2021 |
| Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology. | Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology.
Biasella F, Plössl K, Karl C, Weber BHF, Friedrich U., Free PMC Article | 05/15/2021 |
| Vitronectin regulates the axon specification of mouse cerebellar granule cell precursors via alphavbeta5 integrin in the differentiation stage. | Vitronectin regulates the axon specification of mouse cerebellar granule cell precursors via αvβ5 integrin in the differentiation stage.
Oishi Y, Hashimoto K, Abe A, Kuroda M, Fujii A, Miyamoto Y. | 05/1/2021 |
| Structural Insights into the Interactions of Candidal Enolase with Human Vitronectin, Fibronectin and Plasminogen. | Structural Insights into the Interactions of Candidal Enolase with Human Vitronectin, Fibronectin and Plasminogen.
Satala D, Satala G, Karkowska-Kuleta J, Bukowski M, Kluza A, Rapala-Kozik M, Kozik A., Free PMC Article | 04/17/2021 |
| Functional role of vitronectin in breast cancer. | Functional role of vitronectin in breast cancer.
Bera A, Subramanian M, Karaian J, Eklund M, Radhakrishnan S, Gana N, Rothwell S, Pollard H, Hu H, Shriver CD, Srivastava M., Free PMC Article | 01/16/2021 |
| The iron-regulated surface determinant B (IsdB) protein from Staphylococcus aureus acts as a receptor for the host protein vitronectin. | The iron-regulated surface determinant B (IsdB) protein from Staphylococcus aureus acts as a receptor for the host protein vitronectin.
Pietrocola G, Pellegrini A, Alfeo MJ, Marchese L, Foster TJ, Speziale P., Free PMC Article | 01/16/2021 |
| Calcium and hydroxyapatite binding site of human vitronectin provides insights to abnormal deposit formation. | Calcium and hydroxyapatite binding site of human vitronectin provides insights to abnormal deposit formation.
Shin K, Kent JE, Singh C, Fujimoto LM, Yu J, Tian Y, Im W, Marassi FM., Free PMC Article | 10/3/2020 |
| Integrin alphavbeta3 is a promising biomarker alone or in combination with vitronectin for diagnosis and prognosis of early stage breast cancer. | Evaluation of Serum Integrin αvβ3 & Vitronectin in the Early Diagnosis of Breast Cancer.
Radwan AF, Ismael OE, Fawzy A, El-Mesallamy HO. | 01/11/2020 |
| Results found that neuroblastoma samples of patients with poor prognostic factors are characterized by the highest territorial VN expression pattern. | Vitronectin as a molecular player of the tumor microenvironment in neuroblastoma.
Burgos-Panadero R, Noguera I, Cañete A, Navarro S, Noguera R., Free PMC Article | 12/28/2019 |
| Exploring the role of the P47 domain, screening of serum proteins showed that vitronectin (VTN) directly binds to 20 residues in the C-terminal region of SE36. VTN co-localized with P47 N-terminal domain of SERA5 in the schizont and merozoite stages | Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5.
Tougan T, Edula JR, Takashima E, Morita M, Shinohara M, Shinohara A, Tsuboi T, Horii T., Free PMC Article | 10/5/2019 |
| blood-derived vitronectin (VTN) rapidly and potently activates leukemia inhibitory factor (LIF) and pro-inflammatory interleukin 6 (IL-6) in vitro and after vascular injury in the brain. | Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin-FAK and uPAR signaling.
Keasey MP, Jia C, Pimentel LF, Sante RR, Lovins C, Hagg T., Free PMC Article | 08/10/2019 |
| Serum miR-99a-5p is significantly elevated in ovarian cancer patients. Exosomal miR-99a-5p from EOC cells promotes cell invasion by affecting HPMCs through fibronectin and vitronectin upregulation and may serve as a target for inhibiting ovarian cancer progression. | Exosomal miR-99a-5p is elevated in sera of ovarian cancer patients and promotes cancer cell invasion by increasing fibronectin and vitronectin expression in neighboring peritoneal mesothelial cells.
Yoshimura A, Sawada K, Nakamura K, Kinose Y, Nakatsuka E, Kobayashi M, Miyamoto M, Ishida K, Matsumoto Y, Kodama M, Hashimoto K, Mabuchi S, Kimura T., Free PMC Article | 02/16/2019 |
| Results showed that BPIFB1 expression markedly inhibited NPC cell migration, invasion, and lung-metastatic abilities. Additionally, identification of two BPIFB1-interacting proteins, VTN and VIM, showed that BPIFB1 reduced VTN expression and the formation of a VTN-integrin alphaV complex in NPC cells, leading to inhibition of the FAK/Src/ERK signalling pathway. | BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM.
Wei F, Wu Y, Tang L, He Y, Shi L, Xiong F, Gong Z, Guo C, Li X, Liao Q, Zhang W, Zhou M, Xiang B, Li X, Li Y, Li G, Xiong W, Zeng Z., Free PMC Article | 01/19/2019 |
| Insulin resistance and age independently predicted VTN levels. VTN may be a candidate target for the appraisal of hepatic insulin resistance in patients with type 2 diabetes. | The relationship between vitronectin and hepatic insulin resistance in type 2 diabetes mellitus.
Cao Y, Li X, Lu C, Zhan X. | 11/17/2018 |
| The 10 kDa C-terminal fragment of the ECM protein vitronectin (VTN) was then selected as a promising circulating biomarker in discriminating Nonalcoholic steatohepatitis. | Overexpression of the Vitronectin V10 Subunit in Patients with Nonalcoholic Steatohepatitis: Implications for Noninvasive Diagnosis of NASH.
Del Ben M, Overi D, Polimeni L, Carpino G, Labbadia G, Baratta F, Pastori D, Noce V, Gaudio E, Angelico F, Mancone C., Free PMC Article | 08/18/2018 |
| The authors observed that exposure of Burkholderia pseudomallei and the closely related yet avirulent Burkholderia thailandensis to human plasma increased epithelial cell invasion by >20 fold. Receptor blocking studies with RGD-domain containing peptide and alphaV beta3 blocking antibody identified complement-activated vitronectin as the factor facilitating this invasion. | Complement-activated vitronectin enhances the invasion of nonphagocytic cells by bacterial pathogens Burkholderia and Klebsiella.
Tan YH, Gamage AM, Gan YH. | 03/10/2018 |
| Additionally, the authors utilized vitroenctin-derived peptides to map the minimal Rickettsia conorii Adr1/human vitronectin interaction to the C-terminal region of vitronectin. | The Rickettsia conorii Adr1 Interacts with the C-Terminus of Human Vitronectin in a Salt-Sensitive Manner.
Fish AI, Riley SP, Singh B, Riesbeck K, Martinez JJ., Free PMC Article | 09/23/2017 |
| We show that small N-terminal fragments of VN consistent with processing of the RGD motif are present in liquid biopsies of cancer patients as well as in the urine of healthy individuals. | Urokinase links plasminogen activation and cell adhesion by cleavage of the RGD motif in vitronectin.
De Lorenzi V, Sarra Ferraris GM, Madsen JB, Lupia M, Andreasen PA, Sidenius N., Free PMC Article | 08/19/2017 |