Chondroitin polymerizing factor promotes development and progression of colorectal cancer via facilitating transcription of VEGFB. | Chondroitin polymerizing factor promotes development and progression of colorectal cancer via facilitating transcription of VEGFB. Huang Y, Zhang Z, Tong H, Qin W, Li Q, Ma L, Ren Z, Chen W, Zhang Y, Zhong Y, Yao L, Zhou P., Free PMC Article | 06/7/2024 |
Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway. | Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway. Zhang H, Hu S, Sanches JGP, Li Y, Wei Y, Pu C, Zhang J. | 05/31/2024 |
VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway. | VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway. Lee C, Chen R, Sun G, Liu X, Lin X, He C, Xing L, Liu L, Jensen LD, Kumar A, Langer HF, Ren X, Zhang J, Huang L, Yin X, Kim J, Zhu J, Huang G, Li J, Lu W, Chen W, Liu J, Hu J, Sun Q, Lu W, Fang L, Wang S, Kuang H, Zhang Y, Tian G, Mi J, Kang BA, Narazaki M, Prodeus A, Schoonjans L, Ornitz DM, Gariepy J, Eelen G, Dewerchin M, Yang Y, Ou JS, Mora A, Yao J, Zhao C, Liu Y, Carmeliet P, Cao Y, Li X., Free PMC Article | 08/23/2023 |
Increased Serum VEGF-B Level Is Associated With Renal Function Impairment in Patients With Type 2 Diabetes. | Increased Serum VEGF-B Level Is Associated With Renal Function Impairment in Patients With Type 2 Diabetes. Wei Y, Han S, Zhou R, Xu P, Zhou L, Zhu Z, Kan Y, Yang X, Xiang Y, Cao Y, Jin Y, Yan J, Yu X, Wang X, Shang W., Free PMC Article | 04/23/2022 |
The Aryl Hydrocarbon Receptor-Dependent TGF-alpha/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis. | The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis. Cirac A, Tsaktanis T, Beyer T, Linnerbauer M, Andlauer T, Grummel V, Nirschl L, Loesslein L, Quintana FJ, Hemmer B, Rothhammer V., Free PMC Article | 03/5/2022 |
Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin-1. | Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin-1. Mota F, Yelland T, Hutton JA, Parker J, Patsiarika A, Chan AWE, O'Leary A, Fotinou C, Martin JF, Zachary IC, Djordjevic S, Frankel P, Selwood DL., Free PMC Article | 02/26/2022 |
Co-expression of VEGF-B and FLT-1 correlates with malignancy and prognosis of gastric cancer. | Co-expression of VEGF-B and FLT-1 correlates with malignancy and prognosis of gastric cancer. Ma Y, Wang W, Liu L, Liu Y, Bi W. | 02/12/2022 |
Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the Vascular Endothelial Growth Factor Receptor 1 (VEGFR1D2) for anticancer application. | Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the Vascular Endothelial Growth Factor Receptor 1 (VEGFR1D2) for anticancer application. Sadremomtaz A, Ali AM, Jouyandeh F, Balalaie S, Navari R, Broussy S, Mansouri K, Groves MR, Asghari SM., Free PMC Article | 10/9/2021 |
Identification of a Tumor Microenvironment-relevant Gene set-based Prognostic Signature and Related Therapy Targets in Gastric Cancer. | Identification of a Tumor Microenvironment-relevant Gene set-based Prognostic Signature and Related Therapy Targets in Gastric Cancer. Cai WY, Dong ZN, Fu XT, Lin LY, Wang L, Ye GD, Luo QC, Chen YC., Free PMC Article | 05/22/2021 |
Results found that VEGF-B expressions levels were higher in Behcet's disease (BD) patients than those in the healthy group, but this difference did not reach statistical significance. Also, VEGF-B gene expression is significantly higher in patients with vascular involvement (DVT/thrombophlebitis). | The Evaluation of the Relationship between sTREM-1, VEGF-B, and VEGF Gene Expression Levels with Disease Activity of Behçet's Patients. Harmanci K, Akan OY, Pirildar T, Ortan P, Ulman C., Free PMC Article | 03/30/2019 |
vitreous levels increased in neovascular retinal diseases | Evaluation of the growth factors VEGF-a and VEGF-B in the vitreous and serum of patients with macular and retinal vascular diseases. Mesquita J, Castro-de-Sousa JP, Vaz-Pereira S, Neves A, Passarinha LA, Tomaz CT. | 01/26/2019 |
High plasma VEGF-B levels are associated with type 2 diabetes mellitus. | Plasma vascular endothelial growth factor B levels are increased in patients with newly diagnosed type 2 diabetes mellitus and associated with the first phase of glucose-stimulated insulin secretion function of β-cell. Wu J, Wei H, Qu H, Feng Z, Long J, Ge Q, Deng H. | 06/30/2018 |
Data from clinical studies point out the changes in circulating or tissue expression levels of VEGF-B in obese compared with lean patients. | The role of vascular endothelial growth factor-B in metabolic homoeostasis: current evidence. Zafar MI, Zheng J, Kong W, Ye X, Gou L, Regmi A, Chen LL., Free PMC Article | 05/5/2018 |
Cardiac transgenic vascular endothelial growth factor-B overexpression failed to protect heart transplants from ischemia-reperfusion injury. | Vascular Endothelial Growth Factor-B Overexpressing Hearts Are Not Protected From Transplant-Associated Ischemia-Reperfusion Injury. Raissadati A, Tuuminen R, Dashkevich A, Bry M, Kivelä R, Anisimov A, Syrjälä S, Arnaudova R, Rouvinen E, Keränen MA, Krebs R, Nykänen AI, Lemström KB. | 10/14/2017 |
renal VEGF-B expression correlates with the severity of Diabetic Kidney Disease. | Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease. Falkevall A, Mehlem A, Palombo I, Heller Sahlgren B, Ebarasi L, He L, Ytterberg AJ, Olauson H, Axelsson J, Sundelin B, Patrakka J, Scotney P, Nash A, Eriksson U. | 07/15/2017 |
Data show that metformin treatment reduces serum vascular endothelial growth factor B (VEGF-B) levels and ameliorates insulin resistance. | Serum vascular endothelial growth factor B is elevated in women with polycystic ovary syndrome and can be decreased with metformin treatment. Cheng F, Zhao L, Wu Y, Huang T, Yang G, Zhang Z, Wu Y, Jia F, Wu J, Chen C, Liu D. | 12/17/2016 |
VEGFA and VEGFB associated sub-network, kinase insert domain receptor (KDR), fibronectin 1 (FN1), transforming growth factor beta induced (TGFBI) and proliferating cell nuclear antigen (PCNA) found to interact with at least two of the three hub genes. | Bioinformatics Analyses of the Role of Vascular Endothelial Growth Factor in Patients with Non-Small Cell Lung Cancer. Wang Y, Huang L, Wu S, Jia Y, Yang Y, Luo L, Bi A, Fang M., Free PMC Article | 04/2/2016 |
Frameshift mutations of VEGFB gene is associated with stomach and colorectal cancers. | Frameshift mutation of an angiogenesis factor VEGFB and its mutational heterogeneity in colorectal cancers. Choi MR, Yoo NJ, Lee SH, An CH. | 03/12/2016 |
plasma VEGF levels before treatment were lower in patients with schizophrenia and that their VEGF levels increased after treatment. | Alterations in plasma vascular endothelial growth factor levels in patients with schizophrenia before and after treatment. Lee BH, Hong JP, Hwang JA, Ham BJ, Na KS, Kim WJ, Trigo J, Kim YK. | 01/2/2016 |
fluid shear stress induces the synthesis of Insulin growth factor-2 and vascular endothelial growth factor (VEGF) B and D, which in turn transactivate MMP-12. | Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways. Wang P, Chen SH, Hung WC, Paul C, Zhu F, Guan PP, Huso DL, Kontrogianni-Konstantopoulos A, Konstantopoulos K., Free PMC Article | 11/28/2015 |
MMP9 may activate VEGF-B via PI3K/Akt signaling pathway. | Vascular endothelial growth factor B coordinates metastasis of non-small cell lung cancer. Liu G, Xu S, Jiao F, Ren T, Li Q. | 06/20/2015 |
Roles of vascular endothelial growth factor in amyotrophic lateral sclerosis. | Roles of vascular endothelial growth factor in amyotrophic lateral sclerosis. Pronto-Laborinho AC, Pinto S, de Carvalho M., Free PMC Article | 02/14/2015 |
Low VEGFB and VEGFD gene expression is associated with early-stage non-small cell lung cancer. | A gene signature combining the tissue expression of three angiogenic factors is a prognostic marker in early-stage non-small cell lung cancer. Sanmartín E, Sirera R, Usó M, Blasco A, Gallach S, Figueroa S, Martínez N, Hernando C, Honguero A, Martorell M, Guijarro R, Rosell R, Jantus-Lewintre E, Camps C. | 11/8/2014 |
Our study suggested that VEGF-B was an angiogenesis factor in vitro and that ERK1/2 and p38-related signaling pathways were involved in these VEGF-B activities. | Effects of vascular endothelial growth factor B on proliferation and migration in EA.Hy926 cells. Zhang GH, Qin R, Zhang SH, Zhu H. | 10/4/2014 |
VEGF-B has possible roles in cardiac protection, energy metabolism support, and neuroprotectin [review] | Vascular endothelial growth factor-B in physiology and disease. Bry M, Kivelä R, Leppänen VM, Alitalo K. | 09/6/2014 |