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    UMOD uromodulin [ Homo sapiens (human) ]

    Gene ID: 7369, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Serum uromodulin associates with kidney function and outcome in a cohort of hospitalised COVID-19 patients.

    Serum uromodulin associates with kidney function and outcome in a cohort of hospitalised COVID-19 patients.
    Wendt R, Macholz M, Kalbitz S, Herrmann N, Herbst V, Hammes T, Kai M, Ankersmit HJ, Beige J, Lübbert C, Graf A, Scherberich J., Free PMC Article

    10/31/2024
    Uromodulin in sepsis and severe pneumonia: a two-sample Mendelian randomization study.

    Uromodulin in sepsis and severe pneumonia: a two-sample Mendelian randomization study.
    Eriksson M, Lipcsey M, Ilboudo Y, Yoshiji S, Richards B, Hultström M.

    04/25/2024
    UROMODULIN - A LINK BETWEEN SODIUM EXCRETION AND ALTERATION IN CIRCADIAN BLOOD PRESSURE PATTERN IN PREHYPERTENSIVES.

    UROMODULIN - A LINK BETWEEN SODIUM EXCRETION AND ALTERATION IN CIRCADIAN BLOOD PRESSURE PATTERN IN PREHYPERTENSIVES.
    Josipović J, Šimičević L, Dika Ž, Bulj N, Vrsalović M, Jelaković B., Free PMC Article

    04/3/2024
    The Versatile Role of Uromodulin in Renal Homeostasis and Its Relevance in Chronic Kidney Disease.

    The Versatile Role of Uromodulin in Renal Homeostasis and Its Relevance in Chronic Kidney Disease.
    Takata T, Isomoto H., Free PMC Article

    01/8/2024
    Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene.

    Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene.
    Nanamatsu A, Micanovic R, Khan S, El-Achkar TM, LaFavers KA., Free PMC Article

    09/29/2023
    Longitudinal effects of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in older women and men.

    Longitudinal effects of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in older women and men.
    Algharably EA, Villagomez Fuentes LE, Toepfer S, König M, Regitz-Zagrosek V, Bertram L, Bolbrinker J, Demuth I, Kreutz R., Free PMC Article

    08/10/2023
    Kidney function may partially mediated the protective effect of urinary uromodulin on kidney stone.

    Kidney function may partially mediated the protective effect of urinary uromodulin on kidney stone.
    Jian Z, Yuan C, Xiong Z, Li H, Jin X, Wang K.

    04/12/2023
    A founder UMOD variant is a common cause of hereditary nephropathy in the British population.

    A founder UMOD variant is a common cause of hereditary nephropathy in the British population.
    Valluru MK, Chung NK, Gilchrist M, Butland L, Cook J, Takou A, Dixit A, Weedon MN, Ong ACM, Genomics England Research Consortium., Free PMC Article

    03/24/2023
    SPP1 and UMOD gene variants are synergistically associated with risk of renal stone disease.

    SPP1 and UMOD gene variants are synergistically associated with risk of renal stone disease.
    Patel YP, Patel SG, Patel SB, Parikh A, Soni S, Srivastava R, Raval C, Raval MA, Nand Pandey S, Ganpule AP, Desai MR.

    03/15/2023
    Uromodulin and CKD: insight into variant pathogenicity.

    Uromodulin and CKD: insight into variant pathogenicity.
    Franceschini N, Berg JS.

    03/10/2023
    A UMOD variant with intermediate effects.

    A UMOD variant with intermediate effects.
    Carney EF.

    01/14/2023
    Effect of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in a community-based cohort of older adults.

    Effect of a common UMOD variant on kidney function, blood pressure, cognitive and physical function in a community-based cohort of older adults.
    Villagomez Fuentes LE, Algharably EA, Toepfer S, König M, Demuth I, Bertram L, Kreutz R, Bolbrinker J., Free PMC Article

    11/19/2022
    An intermediate-effect size variant in UMOD confers risk for chronic kidney disease.

    An intermediate-effect size variant in UMOD confers risk for chronic kidney disease.
    Olinger E, Schaeffer C, Kidd K, Elhassan EAE, Cheng Y, Dufour I, Schiano G, Mabillard H, Pasqualetto E, Hofmann P, Fuster DG, Kistler AD, Wilson IJ, Kmoch S, Raymond L, Robert T, Genomics England Research Consortium, Eckardt KU, Bleyer AJ Sr, Köttgen A, Conlon PJ, Wiesener M, Sayer JA, Rampoldi L, Devuyst O., Free PMC Article

    08/27/2022
    Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.

    Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
    Stsiapanava A, Xu C, Nishio S, Han L, Yamakawa N, Carroni M, Tunyasuvunakool K, Jumper J, de Sanctis D, Wu B, Jovine L., Free PMC Article

    04/23/2022
    Systematic analysis of modulating activities of native human urinary Tamm-Horsfall protein on calcium oxalate crystallization, growth, aggregation, crystal-cell adhesion and invasion through extracellular matrix.

    Systematic analysis of modulating activities of native human urinary Tamm-Horsfall protein on calcium oxalate crystallization, growth, aggregation, crystal-cell adhesion and invasion through extracellular matrix.
    Noonin C, Peerapen P, Yoodee S, Kapincharanon C, Kanlaya R, Thongboonkerd V.

    04/2/2022
    Correlation of serum uromodulin levels with renal fibrosis and renal function progression in patients with CKD.

    Correlation of serum uromodulin levels with renal fibrosis and renal function progression in patients with CKD.
    Jie C, Yi-Ying Y, Miao C.

    03/19/2022
    UMOD Polymorphisms Associated with Kidney Function, Serum Uromodulin and Risk of Mortality among Patients with Chronic Kidney Disease, Results from the C-STRIDE Study.

    UMOD Polymorphisms Associated with Kidney Function, Serum Uromodulin and Risk of Mortality among Patients with Chronic Kidney Disease, Results from the C-STRIDE Study.
    Wang J, Liu L, He K, Gao B, Wang F, Zhao M, Zhang L, On Behalf Of The Chinese Cohort Study Of Chronic Kidney Disease C-Stride., Free PMC Article

    02/19/2022
    Polymorphism in the GATM Locus Associated with Dialysis-Independent Chronic Kidney Disease but Not Dialysis-Dependent Kidney Failure.

    Polymorphism in the GATM Locus Associated with Dialysis-Independent Chronic Kidney Disease but Not Dialysis-Dependent Kidney Failure.
    Šalamon Š, Bevc S, Ekart R, Hojs R, Potočnik U., Free PMC Article

    12/18/2021
    A novel likely pathogenic variant in the UMOD gene in a family with autosomal dominant tubulointerstitial kidney disease: a case report.

    A novel likely pathogenic variant in the UMOD gene in a family with autosomal dominant tubulointerstitial kidney disease: a case report.
    Wang Y, Liu H, He Q, Yi Z, Li Y, Dang X., Free PMC Article

    12/18/2021
    Study of Uromodulin Gene Polymorphism in Egyptian Patients with End-Stage Renal Disease.

    Study of Uromodulin Gene Polymorphism in Egyptian Patients with End-Stage Renal Disease.
    Abdelsalam M, Motawea M, Kyrillos F, Abdel-Razik A, Zaki MES, Abdel-Wahab A.

    12/11/2021
    ASSOCIATION OF GENETIC POLYMORPHISM AND EXPRESSION OF UMOD GENE AND CHRONIC KIDNEY DISEASE.

    ASSOCIATION OF GENETIC POLYMORPHISM AND EXPRESSION OF UMOD GENE AND CHRONIC KIDNEY DISEASE.
    Hasan FT, Mohey MA.

    12/4/2021
    Mechanistic interactions of uromodulin with the thick ascending limb: perspectives in physiology and hypertension.

    Mechanistic interactions of uromodulin with the thick ascending limb: perspectives in physiology and hypertension.
    Boder P, Mary S, Mark PB, Leiper J, Dominiczak AF, Padmanabhan S, Rampoldi L, Delles C., Free PMC Article

    10/23/2021
    SPTB related spherocytosis in a three-generation family presenting with kidney failure in adulthood due to co-occurrence of UMOD disease causing variant.

    SPTB related spherocytosis in a three-generation family presenting with kidney failure in adulthood due to co-occurrence of UMOD disease causing variant.
    Meglic A, Debeljak M, Kovac J, Trampus Bakija A, Rajic V, Kojc N, Trebusak Podkrajsek K.

    09/11/2021
    Importance of glycosylation in the interaction of Tamm-Horsfall protein with collectin-11 and acute kidney injury.

    Importance of glycosylation in the interaction of Tamm-Horsfall protein with collectin-11 and acute kidney injury.
    Gong K, Xia M, Wang Y, Bai L, Ying W, Zhu F, Chen Y., Free PMC Article

    09/11/2021
    Association of Serum Uromodulin with Death, Cardiovascular Events, and Kidney Failure in CKD.

    Association of Serum Uromodulin with Death, Cardiovascular Events, and Kidney Failure in CKD.
    Steubl D, Schneider MP, Meiselbach H, Nadal J, Schmid MC, Saritas T, Krane V, Sommerer C, Baid-Agrawal S, Voelkl J, Kotsis F, Köttgen A, Eckardt KU, Scherberich JE, GCKD Study Investigators., Free PMC Article

    09/11/2021
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