| Global analysis of binding sites of U2AF1 and ZRSR2 reveals RNA elements required for mutually exclusive splicing by the U2- and U12-type spliceosome. | Global analysis of binding sites of U2AF1 and ZRSR2 reveals RNA elements required for mutually exclusive splicing by the U2- and U12-type spliceosome.
Kwon YS, Jin SW, Song H., Free PMC Article | 02/15/2024 |
| Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis. | Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis.
Gurule NJ, Malcolm KC, Harris C, Knapp JR, O'Connor BP, McClendon J, Janssen WJ, Lee FFY, Price C, Osaghae-Nosa J, Wheeler EA, McMahon CM, Pietras EM, Pollyea DA, Alper S., Free PMC Article | 12/5/2023 |
| U2AF1 in various neoplastic diseases and relevant targeted therapies for malignant cancers with complex mutations (Review). | U2AF1 in various neoplastic diseases and relevant targeted therapies for malignant cancers with complex mutations (Review).
Nian Q, Li Y, Li J, Zhao L, Rodrigues Lima F, Zeng J, Liu R, Ye Z., Free PMC Article | 11/30/2023 |
| Patients with telomere biology disorders show context specific somatic mosaic states with high frequency of U2AF1 variants. | Patients with telomere biology disorders show context specific somatic mosaic states with high frequency of U2AF1 variants.
Ferrer A, Lasho T, Fernandez JA, Steinauer NP, Simon RA, Finke CM, Carmona EM, Wylam ME, Ongie LJ, Burnap BN, Arana Yi C, Sproat LZ, Foran J, Badar T, Mangaonkar AA, Patnaik MM. | 11/18/2023 |
| U2AF1 pathogenic variants in myeloid neoplasms and precursor states: distribution of co-mutations and prognostic heterogeneity. | U2AF1 pathogenic variants in myeloid neoplasms and precursor states: distribution of co-mutations and prognostic heterogeneity.
Badar T, Vanegas YAM, Nanaa A, Foran JM, Al-Kali A, Mangaonkar A, Murthy H, Alkhateeb HB, Viswanatha D, He R, Shah M, Yi CA, Litzow MR, Gangat N, Tefferi A, Patnaik MM., Free PMC Article | 09/27/2023 |
| Full-length transcript alterations in human bronchial epithelial cells with U2AF1 S34F mutations. | Full-length transcript alterations in human bronchial epithelial cells with U2AF1 S34F mutations.
Soulette CM, Hrabeta-Robinson E, Arevalo C, Felton C, Tang AD, Marin MG, Brooks AN., Free PMC Article | 08/3/2023 |
| Clinical and molecular spectrum and prognostic outcomes of U2AF1 mutant clonal hematopoiesis- a prospective mayo clinic cohort study. | Clinical and molecular spectrum and prognostic outcomes of U2AF1 mutant clonal hematopoiesis- a prospective mayo clinic cohort study.
Pritzl SL, Gurney M, Badar T, Ferrer A, Lasho T, Finke C, Mangaonkar A, McCullough K, Gangat N, Fernandez J, Al-Kali A, Viswanatha D, He R, Foran J, Patnaik MM. | 02/4/2023 |
| U2AF1 and EZH2 mutations are associated with nonimmune hemolytic anemia in myelodysplastic syndromes. | U2AF1 and EZH2 mutations are associated with nonimmune hemolytic anemia in myelodysplastic syndromes.
Komrokji R, Aguirre LE, Al Ali N, Hussaini M, Sallman D, Rollison D, Padron E., Free PMC Article | 01/11/2023 |
| U2AF1 mutation connects DNA damage to the alternative splicing of RAD51 in lung adenocarcinomas. | U2AF1 mutation connects DNA damage to the alternative splicing of RAD51 in lung adenocarcinomas.
Chen C, Zhou P, Zhang Z, Liu Y. | 06/18/2022 |
| Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies. | Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.
Biancon G, Joshi P, Zimmer JT, Hunck T, Gao Y, Lessard MD, Courchaine E, Barentine AES, Machyna M, Botti V, Qin A, Gbyli R, Patel A, Song Y, Kiefer L, Viero G, Neuenkirchen N, Lin H, Bewersdorf J, Simon MD, Neugebauer KM, Tebaldi T, Halene S., Free PMC Article | 04/16/2022 |
| Decreased CD177(pos) neutrophils in myeloid neoplasms is associated with NPM1, RUNX1, TET2, and U2AF1 S34F mutations. | Decreased CD177(pos) neutrophils in myeloid neoplasms is associated with NPM1, RUNX1, TET2, and U2AF1 S34F mutations.
Alayed K, Meyerson HJ. | 03/5/2022 |
| Identification of a small molecule splicing inhibitor targeting UHM domains. | Identification of a small molecule splicing inhibitor targeting UHM domains.
Kobayashi A, Clément MJ, Craveur P, El Hage K, Salone JM, Bollot G, Pastré D, Maucuer A. | 02/19/2022 |
| Bilineal evolution of a U2AF1-mutated clone associated with acquisition of distinct secondary mutations. | Bilineal evolution of a U2AF1-mutated clone associated with acquisition of distinct secondary mutations.
Montgomery ND, Galeotti J, Johnson SM, Commander L, Weimer ET, Chandra PK, Nazir T, Alexander TB, Zeidner JF, Foster MC., Free PMC Article | 01/15/2022 |
| Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations. | Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations.
Cheruiyot A, Li S, Nonavinkere Srivatsan S, Ahmed T, Chen Y, Lemacon DS, Li Y, Yang Z, Wadugu BA, Warner WA, Pruett-Miller SM, Obeng EA, Link DC, He D, Xiao F, Wang X, Bailis JM, Walter MJ, You Z., Free PMC Article | 01/8/2022 |
| Splice site m(6)A methylation prevents binding of U2AF35 to inhibit RNA splicing. | Splice site m(6)A methylation prevents binding of U2AF35 to inhibit RNA splicing.
Mendel M, Delaney K, Pandey RR, Chen KM, Wenda JM, Vågbø CB, Steiner FA, Homolka D, Pillai RS., Free PMC Article | 01/8/2022 |
| [Effect of U2AF1 Mutation to Inflammatory Cytokine Expression in SKM-1 Cells through FOXO3a-Bim Signaling Pathway]. | [Effect of U2AF1 Mutation to Inflammatory Cytokine Expression in SKM-1 Cells through FOXO3a-Bim Signaling Pathway].
Zhu YQ, Wu LY. | 12/18/2021 |
| U2AF1 mutation promotes tumorigenicity through facilitating autophagy flux mediated by FOXO3a activation in myelodysplastic syndromes. | U2AF1 mutation promotes tumorigenicity through facilitating autophagy flux mediated by FOXO3a activation in myelodysplastic syndromes.
Zhu Y, Song D, Guo J, Jin J, Tao Y, Zhang Z, Xu F, He Q, Li X, Chang C, Wu L., Free PMC Article | 09/25/2021 |
| Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence. | Prevalent intron retention fine-tunes gene expression and contributes to cellular senescence.
Yao J, Ding D, Li X, Shen T, Fu H, Zhong H, Wei G, Ni T., Free PMC Article | 09/4/2021 |
| U2AF1 expression is a novel and independent prognostic indicator of childhood T-lineage acute lymphoblastic leukemia. | U2AF1 expression is a novel and independent prognostic indicator of childhood T-lineage acute lymphoblastic leukemia.
Zhang P, Zhang Y, Li X, Ying P, Tang Y. | 08/21/2021 |
| Down regulation of U2AF1 promotes ARV7 splicing and prostate cancer progression. | Down regulation of U2AF1 promotes ARV7 splicing and prostate cancer progression.
Cao H, Wang D, Gao R, Chen L, Feng Y. | 08/14/2021 |
| Prognostic significance of U2AF1 mutations in myelodysplastic syndromes: a meta-analysis. | Prognostic significance of U2AF1 mutations in myelodysplastic syndromes: a meta-analysis.
Li B, Zou D, Yang S, Ouyang G, Mu Q., Free PMC Article | 06/19/2021 |
| U2AF - Hypoxia-induced fas alternative splicing regulator. | U2AF - Hypoxia-induced fas alternative splicing regulator.
Vilys L, Peciuliene I, Jakubauskiene E, Zinkeviciute R, Makino Y, Kanopka A. | 06/19/2021 |
| The core spliceosomal factor U2AF1 controls cell-fate determination via the modulation of transcriptional networks. | The core spliceosomal factor U2AF1 controls cell-fate determination via the modulation of transcriptional networks.
Laaref AM, Manchon L, Bareche Y, Lapasset L, Tazi J., Free PMC Article | 05/15/2021 |
| The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation. | The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation.
Herdt O, Reich S, Medenbach J, Timmermann B, Olofsson D, Preußner M, Heyd F., Free PMC Article | 05/15/2021 |
| Deoxynivalenol globally affects the selection of 3' splice sites in human cells by suppressing the splicing factors, U2AF1 and SF1. | Deoxynivalenol globally affects the selection of 3' splice sites in human cells by suppressing the splicing factors, U2AF1 and SF1.
Hu Z, Sun Y, Chen J, Zhao Y, Qiao H, Chen R, Wen X, Deng Y, Wen J., Free PMC Article | 05/1/2021 |