| Structural and thermodynamic characterization of a highly amyloidogenic dimer of transthyretin involved in a severe cardiomyopathy. | Structural and thermodynamic characterization of a highly amyloidogenic dimer of transthyretin involved in a severe cardiomyopathy.
Martins LDA, Ferreira PS, Leitão Dos Santos OA, Martins LO, Cabral Fernandes Barroso LG, Pereira HM, Waddington-Cruz M, Palhano FL, Foguel D., Free PMC Article | 10/9/2024 |
| Transthyretin monomers: a new plasma biomarker for pre-symptomatic transthyretin-related amyloidosis. | Transthyretin monomers: a new plasma biomarker for pre-symptomatic transthyretin-related amyloidosis.
Costa-Rodrigues D, Leite JP, Saraiva MJ, Almeida MR, Gales L. | 09/26/2024 |
| Conservation of kinetic stability, but not the unfolding mechanism, between human transthyretin and a transthyretin-related enzyme. | Conservation of kinetic stability, but not the unfolding mechanism, between human transthyretin and a transthyretin-related enzyme.
Jäger M, Kelly JW, Gruebele M., Free PMC Article | 09/20/2024 |
| Conformational Dynamics of an Amyloidogenic Intermediate of Transthyretin: Implications for Structural Remodeling and Amyloid Formation. | Conformational Dynamics of an Amyloidogenic Intermediate of Transthyretin: Implications for Structural Remodeling and Amyloid Formation.
Leach BI, Ferguson JA, Morgan G, Sun X, Kroon G, Oyen D, Dyson HJ, Wright PE., | 09/12/2024 |
| Cardiovascular autonomic failure in hereditary transthyretin amyloidosis and TTR carriers is an early and progressive disease marker. | Cardiovascular autonomic failure in hereditary transthyretin amyloidosis and TTR carriers is an early and progressive disease marker.
Chiaro G, Stancanelli C, Koay S, Vichayanrat E, Sander L, Ingle GT, McNamara P, Carr AS, Wechalekar AD, Whelan CJ, Gillmore JD, Hawkins PN, Reilly MM, Mathias CJ, Iodice V. | 08/16/2024 |
| Modeling transthyretin (TTR) amyloid diseases, from monomer to amyloid fibrils. | Modeling transthyretin (TTR) amyloid diseases, from monomer to amyloid fibrils.
Criddle RS, Hansen LD, Woodfield BF, Tolley HD., Free PMC Article | 06/17/2024 |
| Scintigraphic and Echocardiographic Study of Patients with Pathogenic or Probably Pathogenic Variants of the TTR Gene without Overt Cardiac Involvement. | Scintigraphic and Echocardiographic Study of Patients with Pathogenic or Probably Pathogenic Variants of the TTR Gene without Overt Cardiac Involvement.
Silva TO, Darzé ES, Costa MM, José Junior L, Ximenes AAB, Fernandes F, Rocha MS, Noya-Rabelo MM, Ritt LEF., Free PMC Article | 05/29/2024 |
| Targeting TNF-alpha-induced expression of TTR and RAGE in rheumatoid arthritis: Apigenin's mediated therapeutic approach. | Targeting TNF-α-induced expression of TTR and RAGE in rheumatoid arthritis: Apigenin's mediated therapeutic approach.
Monu, Agnihotri P, Saquib M, Biswas S. | 05/28/2024 |
| Altered gut microbiota in Taiwanese A97S predominant transthyretin amyloidosis with polyneuropathy. | Altered gut microbiota in Taiwanese A97S predominant transthyretin amyloidosis with polyneuropathy.
Chen CC, Tseng PH, Hsueh HW, Chiang MC, Tzeng SR, Chiang TH, Wu MS, Hsieh ST, Chao CC., Free PMC Article | 03/19/2024 |
| Rare c.302C>T TTR Variant Associated with Transthyretin Amyloidosis. | Rare c.302C>T TTR Variant Associated with Transthyretin Amyloidosis.
Žebrauskienė D, Sadauskienė E, Masiulienė R, Aidietienė S, Šiaudinienė A, Pečeliūnas V, Žukauskaitė G, Žurauskas E, Valevičienė N, Barysienė J, Preikšaitienė E., Free PMC Article | 02/28/2024 |
| Prevalence of transthyretin amyloid cardiomyopathy in patients admitted for acute heart failure. | Prevalence of transthyretin amyloid cardiomyopathy in patients admitted for acute heart failure.
Spaccavento A, Rodríguez MDR, Meretta A, Elissamburu P, Carvelli V, Gobbo M, Rosa D, Masoli O, Conde D, Costabel JP. | 02/20/2024 |
| Transthyretin-Regulated Diabetic Retinopathy Through the VEGFA/PI3K/AKT Pathway. | Transthyretin-Regulated Diabetic Retinopathy Through the VEGFA/PI3K/AKT Pathway.
Liu L, Gao Y, Yao S., Free PMC Article | 01/31/2024 |
| Mapping cellular response to destabilized transthyretin reveals cell- and amyloidogenic protein-specific signatures. | Mapping cellular response to destabilized transthyretin reveals cell- and amyloidogenic protein-specific signatures.
Ghosh S, Villacorta-Martin C, Lindstrom-Vautrin J, Kenney D, Golden CS, Edwards CV, Sanchorawala V, Connors LH, Giadone RM, Murphy GJ. | 01/30/2024 |
| Position statement on the non-invasive diagnosis of patients with ATTR pardiac amyloidosis, endorsed by the Hellenic Society of Nuclear Cardiology, for the Nuclear Medicine practitioners. | Position statement on the non-invasive diagnosis of patients with ATTR pardiac amyloidosis, endorsed by the Hellenic Society of Nuclear Cardiology, for the Nuclear Medicine practitioners.
Koutelou M, Prassopoulos V, Lamprakos L, Zissimopoulos A, Chatzipanagiotou T, Mastorakou A, Doumas A. | 01/4/2024 |
| Characterization of the G-quadruplexes in the transthyretin gene and its role in silencing transthyretin mRNA transcription. | Characterization of the G-quadruplexes in the transthyretin gene and its role in silencing transthyretin mRNA transcription.
Huang P, Li X, Tan Z, Wang Y, Yan J. | 12/27/2023 |
| Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis. | Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis.
Steinebrei M, Baur J, Pradhan A, Kupfer N, Wiese S, Hegenbart U, Schönland SO, Schmidt M, Fändrich M., Free PMC Article | 11/27/2023 |
| A 15-year consolidated overview of data in over 6000 patients from the Transthyretin Amyloidosis Outcomes Survey (THAOS). | A 15-year consolidated overview of data in over 6000 patients from the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Gentile L, Coelho T, Dispenzieri A, Conceição I, Waddington-Cruz M, Kristen A, Wixner J, Diemberger I, Gonzalez-Moreno J, Cariou E, Maurer MS, Planté-Bordeneuve V, Garcia-Pavia P, Tournev I, Gonzalez-Costello J, Duarte AG, Grogan M, Mazzeo A, Chapman D, Gupta P, Glass O, Amass L, THAOS investigators., Free PMC Article | 11/15/2023 |
| Decreased expression of S100A8/A9 in V30M related ATTRv amyloidosis. | Decreased expression of S100A8/A9 in V30M related ATTRv amyloidosis.
Moreira J, Martins S, Saraiva M, Saraiva MJ. | 11/3/2023 |
| Transthyretin promotes the invasion of combined hepatocellular cholangiocarcinoma by tumor-associated macrophages. | Transthyretin promotes the invasion of combined hepatocellular cholangiocarcinoma by tumor-associated macrophages.
Ke K, Lin J, Huang N, Yan L, Liao R, Yang W., Free PMC Article | 10/30/2023 |
| Musculoskeletal manifestations associated with transthyretin-mediated (ATTR) amyloidosis: a systematic review. | Musculoskeletal manifestations associated with transthyretin-mediated (ATTR) amyloidosis: a systematic review.
Aldinc E, Campbell C, Gustafsson F, Beveridge A, Macey R, Marr L, Summers C, Zhang D., Free PMC Article | 09/28/2023 |
| Cardiovascular Disease and Mortality in Black Women Carrying the Amyloidogenic V122I Transthyretin Gene Variant. | Cardiovascular Disease and Mortality in Black Women Carrying the Amyloidogenic V122I Transthyretin Gene Variant.
Haring B, Hunt RP, Shadyab AH, Eaton C, Kaplan R, Martin LW, Panjrath G, Kuller LH, Assimes T, Kooperberg C, Wassertheil-Smoller S., Free PMC Article | 09/13/2023 |
| Clinical Penetrance of the Transthyretin V122I Variant in Older Black Patients With Heart Failure: The SCAN-MP (Screening for Cardiac Amyloidosis With Nuclear Imaging in Minority Populations) Study. | Clinical Penetrance of the Transthyretin V122I Variant in Older Black Patients With Heart Failure: The SCAN-MP (Screening for Cardiac Amyloidosis With Nuclear Imaging in Minority Populations) Study.
Madhani A, Sabogal N, Massillon D, Paul LD, Rodriguez C, Fine D, Helmke S, Winburn M, Kurian D, Raiszadeh F, Teruya S, Cohn E, Einstein AJ, Miller EJ, Connors LH, Maurer MS, Ruberg FL., Free PMC Article | 08/30/2023 |
| Hereditary transthyretin amyloidosis caused by p.Ser43Asn variant. A new endemic variant in Ecuador. | Hereditary transthyretin amyloidosis caused by p.Ser43Asn variant. A new endemic variant in Ecuador.
Porres-López E, de Frutos F, Silva-Hernández L, Galán L, González-López E, García-Pavía P. | 06/30/2023 |
| Transthyretin derived amyloid deposits in the atrium and the aortic valve: insights from multimodality evaluations and mid-term follow up. | Transthyretin derived amyloid deposits in the atrium and the aortic valve: insights from multimodality evaluations and mid-term follow up.
Okada A, Kakuta T, Tadokoro N, Tateishi E, Morita Y, Kitai T, Amaki M, Kanzaki H, Ohta-Ogo K, Ikeda Y, Fukushima S, Fujita T, Kusano K, Noguchi T, Izumi C., Free PMC Article | 06/7/2023 |
| Prevalence of transthyretin-related amyloidosis in Tuscany: Data from the regional population-based registry. | Prevalence of transthyretin-related amyloidosis in Tuscany: Data from the regional population-based registry.
Cappelli F, Del Franco A, Vergaro G, Mazzoni C, Argirò A, Pieroni M, Giacomin E, Poli S, Allinovi M, Olivotto I, Pieroni F, Scaletti C, Emdin M, Perfetto F. | 05/17/2023 |