| Long non-coding RNA KCNQ10T1/miR-19a-3p/SMAD5 axis promotes osteogenic differentiation of mouse bone mesenchymal stem cells. | Long non-coding RNA KCNQ10T1/miR-19a-3p/SMAD5 axis promotes osteogenic differentiation of mouse bone mesenchymal stem cells.
Lin H, Nie L, Lu G, Wu H, Xu T., Free PMC Article | 12/18/2023 |
| Cardiac miR-19a/19b was induced and hijacked by CVB3 to facilitate virus replication via targeting viral genomic RdRp-encoding region. | Cardiac miR-19a/19b was induced and hijacked by CVB3 to facilitate virus replication via targeting viral genomic RdRp-encoding region.
Wu Y, Yue Y, Xiong S. | 08/30/2023 |
| MicroRNA-19a Inhibition Directly and Indirectly Ameliorates Th2 Airway Inflammation in Asthma by Targeting RUNX3. | MicroRNA-19a Inhibition Directly and Indirectly Ameliorates Th2 Airway Inflammation in Asthma by Targeting RUNX3.
He S, Zhou J, Ma Y, Wang W, Yang J. | 03/2/2023 |
| Antagonizing microRNA-19a/b augments PTH anabolic action and restores bone mass in osteoporosis in mice. | Antagonizing microRNA-19a/b augments PTH anabolic action and restores bone mass in osteoporosis in mice.
Taipaleenmäki H, Saito H, Schröder S, Maeda M, Mettler R, Ring M, Rollmann E, Gasser A, Haasper C, Gehrke T, Weiss A, Grimm SK, Hesse E., Free PMC Article | 11/19/2022 |
| Exosomal miR-19a decreases insulin production by targeting Neurod1 in pancreatic cancer associated diabetes. | Exosomal miR-19a decreases insulin production by targeting Neurod1 in pancreatic cancer associated diabetes.
Su J, Pang W, Zhang A, Li L, Yao W, Dai X. | 04/9/2022 |
| Inhibition of the lncRNA DANCR attenuates cardiomyocyte injury induced by oxygen-glucose deprivation via the miR-19a-3p/MAPK1 axis. | Inhibition of the lncRNA DANCR attenuates cardiomyocyte injury induced by oxygen-glucose deprivation via the miR-19a-3p/MAPK1 axis.
Ruan Y, Li H, Cao X, Meng S, Jia R, Pu L, Fu H, Jin Z. | 02/12/2022 |
| HDAC3 Downregulation Improves Cerebral Ischemic Injury via Regulation of the SDC1-Dependent JAK1/STAT3 Signaling Pathway Through miR-19a Upregulation. | HDAC3 Downregulation Improves Cerebral Ischemic Injury via Regulation of the SDC1-Dependent JAK1/STAT3 Signaling Pathway Through miR-19a Upregulation.
Fang H, Li HF, He MH, Yang M, Zhang JP. | 12/11/2021 |
| Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer. | Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer.
Wu K, Feng J, Lyu F, Xing F, Sharma S, Liu Y, Wu SY, Zhao D, Tyagi A, Deshpande RP, Pei X, Ruiz MG, Takahashi H, Tsuzuki S, Kimura T, Mo YY, Shiozawa Y, Singh R, Watabe K., Free PMC Article | 09/18/2021 |
| Changes in circulating miRNA19a-3p precede insulin resistance programmed by intra-uterine growth retardation in mice. | Changes in circulating miRNA19a-3p precede insulin resistance programmed by intra-uterine growth retardation in mice.
Saget S, Cong R, Decourtye L, Endale ML, Martinerie L, Girardet C, Perret C, Clemessy M, Leneuve P, Dinard L, Mohand Oumoussa B, Farabos D, Lamazière A, Lombès M, Moldes M, Fève B, Tregouet D, Le Bouc Y, Kappeler L., Free PMC Article | 09/11/2021 |
| MicroRNA-19a Targets Fibroblast Growth Factor-Inducible Molecule 14 and Prevents Tubular Damage in Septic AKI. | MicroRNA-19a Targets Fibroblast Growth Factor-Inducible Molecule 14 and Prevents Tubular Damage in Septic AKI.
Hong J, Hu BC, Xu L, Zheng Y, Shao ZQ, Zhang R, Yang XH, Sun RH, Mo SJ., Free PMC Article | 05/29/2021 |
| Low miR19a expression is associated with pulmonary fibrosis. | Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis.
Souma K, Shichino S, Hashimoto S, Ueha S, Tsukui T, Nakajima T, Suzuki HI, Shand FHW, Inagaki Y, Nagase T, Matsushima K., Free PMC Article | 12/21/2019 |
| In summary, we showed that TBK1 is a target gene of miR-19a in the NF-kappaB pathway and that miR-19a can attenuate the activation of the NF-kappaB signalling pathway by targeting TBK1, thereby reducing the production of pro-inflammatory cytokines and alleviating LPS-induced inflammation.Therefore, miR-19a might possibly be used as a target for the treatment of endometritis. | MiR-19a mediates the negative regulation of the NF-κB pathway in lipopolysaccharide-induced endometritis by targeting TBK1.
Yin N, Yang Y, Wang X, Yang C, Ma X, Shaukat A, Zhao G, Deng G. | 08/3/2019 |
| MiR-19a may mediate gluconeogenesis in hepatocytes by downregulating PTEN expression. | MiR-19a mediates gluconeogenesis by targeting PTEN in hepatocytes.
Dou L, Wang S, Huang X, Sun X, Zhang Y, Shen T, Guo J, Man Y, Tang W, Li J. | 08/18/2018 |
| Delayed Cell Cycle Progression in STHdh(Q111)/Hdh(Q111) Cells, a Cell Model for Huntington's Disease Mediated by microRNA-19a, microRNA-146a and microRNA-432 | Delayed Cell Cycle Progression in STHdh(Q111)/Hdh(Q111) Cells, a Cell Model for Huntington's Disease Mediated by microRNA-19a, microRNA-146a and microRNA-432.
Das E, Jana NR, Bhattacharyya NP. | 07/30/2016 |
| Data indicate phosphatase and tensin homolog protein (PTEN) as the target of microRNA miR-19a. | MiR-19a regulates PTEN expression to mediate glycogen synthesis in hepatocytes.
Dou L, Meng X, Sui X, Wang S, Shen T, Huang X, Guo J, Fang W, Man Y, Xi J, Li J., Free PMC Article | 06/28/2016 |
| antagonism of miR-19a/b in aged mice improves blood flow recovery after ischemia and reduces repression of these targets. | Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling.
Landskroner-Eiger S, Qiu C, Perrotta P, Siragusa M, Lee MY, Ulrich V, Luciano AK, Zhuang ZW, Corti F, Simons M, Montgomery RL, Wu D, Yu J, Sessa WC., Free PMC Article | 01/30/2016 |
| upregulation of miR-19a in asthma may be an indicator and a cause of increased TH2 cytokine production in the airways. | A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.
Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM., Free PMC Article | 01/24/2015 |
| findings support the hypothesis that miR-19a-3p, which regulates tumor-associated macrophages(TAMs)in the breast tumor microenvironment,is able to regulate the phenotype of TAMs by targeting the Fra-1 gene and other genes in its downstream signaling pathway | MicroRNA-19a-3p inhibits breast cancer progression and metastasis by inducing macrophage polarization through downregulated expression of Fra-1 proto-oncogene.
Yang J, Zhang Z, Chen C, Liu Y, Si Q, Chuang TH, Li N, Gomez-Cabrero A, Reisfeld RA, Xiang R, Luo Y. | 07/26/2014 |
| Expression of miR-19a was significantly reduced and TNF-alpha was remarkably increased in dextran sodium sulfate-induced ulcerative colitis in mice, and miR-19a directly regulated TNF-alpha expression. | Role of miR-19a targeting TNF-α in mediating ulcerative colitis.
Chen B, She S, Li D, Liu Z, Yang X, Zeng Z, Liu F. | 02/22/2014 |
| Baitouweng Decoction treatment caused an increased miR-19a expression in mice with ulcerative colitis. | [Effect of Baitouweng Decoction on intestinal miR-19a expression in mice with ulcerative colitis].
Zhou P, Liu F, Luo Q, Sun Y, Ding F, Chen B. | 08/31/2013 |
| Show that miR-19 is sufficient to promote leukaemogenesis in Notch1-induced T-cell acute lymphoblastic leukaemia in vivo. | Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia.
Mavrakis KJ, Wolfe AL, Oricchio E, Palomero T, de Keersmaecker K, McJunkin K, Zuber J, James T, Khan AA, Leslie CS, Parker JS, Paddison PJ, Tam W, Ferrando A, Wendel HG., Free PMC Article | 05/10/2011 |