| Increased serum extracellular vesicle miR-144-3p and miR-486a-3p in a mouse model of adipose tissue regeneration promote hepatocyte proliferation by targeting Txnip. | Increased serum extracellular vesicle miR-144-3p and miR-486a-3p in a mouse model of adipose tissue regeneration promote hepatocyte proliferation by targeting Txnip.
Niitsu Y, Komiya C, Takeuchi A, Hara K, Horino M, Aoki J, Okazaki R, Murakami M, Tsujimoto K, Ikeda K, Yamada T., Free PMC Article | 05/11/2023 |
| Circ_0001058 represses the progression of lung adenocarcinoma through governing of the miR-486-5p/TEK signaling axis. | Circ_0001058 represses the progression of lung adenocarcinoma through governing of the miR-486-5p/TEK signaling axis.
Li W, Wang H, Zheng Y. | 08/27/2022 |
| miR-486 is essential for muscle function and suppresses a dystrophic transcriptome. | miR-486 is essential for muscle function and suppresses a dystrophic transcriptome.
Samani A, Hightower RM, Reid AL, English KG, Lopez MA, Doyle JS, Conklin MJ, Schneider DA, Bamman MM, Widrick JJ, Crossman DK, Xie M, Jee D, Lai EC, Alexander MS., Free PMC Article | 05/14/2022 |
| Transcriptional inhibition of miR-486-3p by BCL6 upregulates Snail and induces epithelial-mesenchymal transition during radiation-induced pulmonary fibrosis. | Transcriptional inhibition of miR-486-3p by BCL6 upregulates Snail and induces epithelial-mesenchymal transition during radiation-induced pulmonary fibrosis.
Yan Z, Ao X, Liang X, Chen Z, Liu Y, Wang P, Wang D, Liu Z, Liu X, Zhu J, Zhou S, Zhou P, Gu Y., Free PMC Article | 05/7/2022 |
| Hormonally Regulated Myogenic miR-486 Influences Sex-specific Differences in Cancer-induced Skeletal Muscle Defects. | Hormonally Regulated Myogenic miR-486 Influences Sex-specific Differences in Cancer-induced Skeletal Muscle Defects.
Wang R, Bhat-Nakshatri P, Zhong X, Zimmers T, Nakshatri H., Free PMC Article | 12/18/2021 |
| Radiation induces submandibular gland damage by affecting Cdkn1a expression and regulating expression of miR-486a-3p in a xerostomia mouse model. | Radiation induces submandibular gland damage by affecting Cdkn1a expression and regulating expression of miR-486a-3p in a xerostomia mouse model.
Wang W, Xiao C, Chen H, Li F, Xia D. | 10/9/2021 |
| Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p. | Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p.
Zhao H, Yang H, Geng C, Chen Y, Tang Y, Li Z, Pang J, Shu T, Nie Y, Liu Y, Jia K, Wang J., Free PMC Article | 07/31/2021 |
| Downregulation of miR4865p alleviates LPSinduced inflammatory injury, oxidative stress and apoptosis in Chondrogenic cell ATDC5 by targeting NRF1. | Downregulation of miR‑486‑5p alleviates LPS‑induced inflammatory injury, oxidative stress and apoptosis in Chondrogenic cell ATDC5 by targeting NRF1.
Chang Q, Ji M, Li C, Geng R. | 04/24/2021 |
| Long noncoding RNA Kcnq1ot1 promotes sC5b-9-induced podocyte pyroptosis by inhibiting miR-486a-3p and upregulating NLRP3. | Long noncoding RNA Kcnq1ot1 promotes sC5b-9-induced podocyte pyroptosis by inhibiting miR-486a-3p and upregulating NLRP3.
Zhang C, Gong Y, Li N, Liu X, Zhang Y, Ye F, Guo Q, Zheng J. | 04/3/2021 |
| MicroRNA-486-5p Promotes Acute Lung Injury via Inducing Inflammation and Apoptosis by Targeting OTUD7B. | MicroRNA-486-5p Promotes Acute Lung Injury via Inducing Inflammation and Apoptosis by Targeting OTUD7B.
Luo Q, Zhu J, Zhang Q, Xie J, Yi C, Li T. | 04/3/2021 |
| The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatin. | The green tea polyphenol epigallocatechin-3-gallate attenuates age-associated muscle loss via regulation of miR-486-5p and myostatin.
Chang YC, Liu HW, Chan YC, Hu SH, Liu MY, Chang SJ. | 11/21/2020 |
| This study indicates that miR-486 promotes proliferation and suppresses apoptosis in myeloid cells by targeting Cebpa in vitro, suggesting that miR-486 and Cebpa might be involved in the expansion of TM-MDSCs in tumor-bearing mice. | MiR-486 promotes proliferation and suppresses apoptosis in myeloid cells by targeting Cebpa in vitro.
Jiang J, Gao Q, Gong Y, Huang L, Lin H, Zhou X, Liang X, Guo W., Free PMC Article | 11/16/2019 |
| Findings indicate that miR-486 is one of the intermediary molecules connecting myostatin signaling and the IGF-1/Akt/mTOR pathway in the regulation of skeletal muscle size. | Myostatin signaling regulates Akt activity via the regulation of miR-486 expression.
Hitachi K, Nakatani M, Tsuchida K. | 11/8/2014 |
| Skeletal muscle-specific miR-486 overexpression in Dmdmdx-5Cv animals decreased levels of DOCK3, reduced PTEN expression, and subsequently increased levels of phosphorylated AKT, which resulted in an overall beneficial effect. | MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.
Alexander MS, Casar JC, Motohashi N, Vieira NM, Eisenberg I, Marshall JL, Gasperini MJ, Lek A, Myers JA, Estrella EA, Kang PB, Shapiro F, Rahimov F, Kawahara G, Widrick JJ, Kunkel LM., Free PMC Article | 08/23/2014 |
| FoxO1 is a dominant mediator of chronic kidney disease-induced muscle wasting, and miR-486 coordinately decreases FoxO1 and PTEN to protect against this catabolic response. | Transcription factor FoxO1, the dominant mediator of muscle wasting in chronic kidney disease, is inhibited by microRNA-486.
Xu J, Li R, Workeneh B, Dong Y, Wang X, Hu Z., Free PMC Article | 10/26/2013 |
| miR-206 and -486 are induced during myoblast differentiation and downregulate Pax7 by directly targeting its 3' untranslated region | miR-206 and -486 induce myoblast differentiation by downregulating Pax7.
Dey BK, Gagan J, Dutta A., Free PMC Article | 01/29/2011 |