| [High expression of Circ-PALLD in heart failure is transcriptionally regulated by the transcription factor GATA4]. | [High expression of Circ-PALLD in heart failure is transcriptionally regulated by the transcription factor GATA4].
Huang Z, Zeng Z, Li J, Cai R, He W, Hu S., Free PMC Article | 09/20/2023 |
| Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities. | Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities.
Mastrototaro G, Carullo P, Zhang J, Scellini B, Piroddi N, Nemska S, Filomena MC, Serio S, Otey CA, Tesi C, Emrich F, Linke WA, Poggesi C, Boncompagni S, Bang ML., Free PMC Article | 04/10/2023 |
| Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation. | Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation.
Ouali BEF, Liu TY, Lu CY, Cheng PY, Huang CL, Li CC, Chiang YC, Wang HV., Free PMC Article | 03/20/2021 |
| Palladin operates downstream of mTOR to modulate axon morphogenesis | Palladin Is a Neuron-Specific Translational Target of mTOR Signaling That Regulates Axon Morphogenesis.
Umegaki Y, Brotons AM, Nakanishi Y, Luo Z, Zhang H, Bonni A, Ikeuchi Y., Free PMC Article | 10/26/2019 |
| Taken together, this study demonstrates that palladin plays an important role in themorphology and dynamic behavior of podocytes in vivo and in vitro. | The Role of Palladin in Podocytes.
Artelt N, Ludwig TA, Rogge H, Kavvadas P, Siegerist F, Blumenthal A, van den Brandt J, Otey CA, Bang ML, Amann K, Chadjichristos CE, Chatziantoniou C, Endlich K, Endlich N., Free PMC Article | 09/14/2019 |
| Study shows palladin is expressed with proper spatio-temporal pattern in the neural folds. It plays a crucial role in regulating mouse cranial neural tube closure by modulating cytoskeleton, proliferation, differentiation, apoptosis, and adhesion of neural epithelium | Lacking of palladin leads to multiple cellular events changes which contribute to NTD.
Tan J, Chen XJ, Shen CL, Zhang HX, Tang LY, Lu SY, Wu WT, Kuang Y, Fei J, Wang ZG., Free PMC Article | 03/31/2018 |
| these results show a new function for PALLD as a crucial regulator of the early phase of phagocytosis by elaborating dynamic actin polymerization and depolymerization | PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.
Sun HM, Chen XL, Chen XJ, Liu J, Ma L, Wu HY, Huang QH, Xi XD, Yin T, Zhu J, Chen Z, Chen SJ. | 09/30/2017 |
| Interactions with phosphatidylinositol 4,5-bisphosphate decrease the actin polymerizing activity of Ig domain 3 of palladin (Palld-Ig3). | Phosphoinositide Binding Inhibits Actin Crosslinking and Polymerization by Palladin.
Yadav R, Vattepu R, Beck MR., Free PMC Article | 06/24/2017 |
| The aggregation of palladin(+/-) platelets was increased in response to low levels of thrombin, U46619, and collagen. This study also reports enhanced spreading of palladin(+/-) platelets on immobilized fibrinogen (Fg) and increased rate of clot retraction in platelet-rich plasma (PRP) containing palladin(+/-) platelets. | Palladin is involved in platelet activation and arterial thrombosis.
Chen X, Fan X, Tan J, Shi P, Wang X, Wang J, Kuang Y, Fei J, Liu J, Dang S, Wang Z. | 04/15/2017 |
| The inhibition of palladin in myoblasts stimulates them to exit the cell cycle and express myogenic markers at the early phases of myogenesis, but retards the formation of multinucleated myotubes via the enhanced activation of myostatin. | Dual roles of palladin protein in in vitro myogenesis: inhibition of early induction but promotion of myotube maturation.
Nguyen NU, Wang HV., Free PMC Article | 04/23/2016 |
| Suggesting that FSH signaling during Sertoli cell maturation regulates subcellular localization of palladin. | Actin dynamics regulate subcellular localization of the F-actin-binding protein PALLD in mouse Sertoli cells.
Niedenberger BA, Chappell VA, Otey CA, Geyer CB. | 05/23/2015 |
| Palladin is required for migration behavior and differentiation potential of cultured myoblast cells. | Actin-associated protein palladin is required for migration behavior and differentiation potential of C2C12 myoblast cells.
Nguyen NU, Liang VR, Wang HV. | 02/28/2015 |
| High levels of palladin expression in cancer associated fibroblasts enhance their ability to remodel the extracellular matrix by regulating the activity of Cdc42. | Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts.
Goicoechea SM, García-Mata R, Staub J, Valdivia A, Sharek L, McCulloch CG, Hwang RF, Urrutia R, Yeh JJ, Kim HJ, Otey CA., Free PMC Article | 05/3/2014 |
| 140 kDa isoform of PALLD predominates in Sertoli cells, and that it is apparently cleaved, with the C-terminus localizing to the nucleus while the N-terminus remains cytoplasmic. | Nuclear localization of the actin regulatory protein Palladin in sertoli cells.
Niedenberger BA, Chappell VK, Kaye EP, Renegar RH, Geyer CB. | 12/14/2013 |
| Palladin mutations that disrupt actin binding show altered cellular distributions and morphology of actin in cells, revealing a functional requirement for the interaction between palladin and actin in vivo. | Structure and function of palladin's actin binding domain.
Beck MR, Dixon RD, Goicoechea SM, Murphy GS, Brungardt JG, Beam MT, Srinath P, Patel J, Mohiuddin J, Otey CA, Campbell SL., Free PMC Article | 12/14/2013 |
| upregulation of 85-90 kDa palladin isoform may play a role in the establishment of the tumor-associated fibroblasts phenotype, and thus in the formation of a desmoplastic tumor microenvironment | Isoform-specific upregulation of palladin in human and murine pancreas tumors.
Goicoechea SM, Bednarski B, Stack C, Cowan DW, Volmar K, Thorne L, Cukierman E, Rustgi AK, Brentnall T, Hwang RF, McCulloch CA, Yeh JJ, Bentrem DJ, Hochwald SN, Hingorani SR, Kim HJ, Otey CA., Free PMC Article | 06/18/2011 |
| Actin associated protein palladin is important for the early smooth muscle cell differentiation. | The actin associated protein palladin is important for the early smooth muscle cell differentiation.
Jin L, Gan Q, Zieba BJ, Goicoechea SM, Owens GK, Otey CA, Somlyo AV., Free PMC Article | 02/26/2011 |
| palladin is dispensable for normal neurite outgrowth in mice | Target deletion of the cytoskeleton-associated protein palladin does not impair neurite outgrowth in mice.
Shu RZ, Zhang F, Liu XS, Li CL, Wang L, Tai YL, Wu XL, Yang X, Liao XD, Jin Y, Gu MM, Huang L, Pang XF, Wang ZG., Free PMC Article | 02/8/2010 |
| results indicate that alpha-actinin, CLP36 and palladin form a protein complex and contribute to regulation of the actin cytoskeleton | Characterization of interaction between CLP36 and palladin.
Maeda M, Asano E, Ito D, Ito S, Hasegawa Y, Hamaguchi M, Senga T. | 01/21/2010 |
| Palladin is essential for expression of the full complement of contractile proteins necessary for optimal force development of smooth muscle cells derived from embryoid bodies | The actin-associated protein Palladin is required for development of normal contractile properties of smooth muscle cells derived from embryoid bodies.
Jin L, Yoshida T, Ho R, Owens GK, Somlyo AV., Free PMC Article | 01/21/2010 |
| expression analysis of the murine palladin isoforms | Comparative expression analysis of the murine palladin isoforms.
Wang HV, Moser M. | 01/21/2010 |
| palladin is crucial for definitive erythropoiesis and erythroblastic island formation | Disruption of palladin leads to defects in definitive erythropoiesis by interfering with erythroblastic island formation in mouse fetal liver.
Liu XS, Li XH, Wang Y, Shu RZ, Wang L, Lu SY, Kong H, Jin YE, Zhang LJ, Fei J, Chen SJ, Chen Z, Gu MM, Lu ZY, Wang ZG. | 01/21/2010 |
| Here, we demonstrate that palladin is a binding partner for profilin, interacting with profilin via a poly proline-containing sequence in the amino-terminal half of palladin. | The proline-rich protein palladin is a binding partner for profilin.
Boukhelifa M, Moza M, Johansson T, Rachlin A, Parast M, Huttelmaier S, Roy P, Jockusch BM, Carpen O, Karlsson R, Otey CA. | 01/21/2010 |
| We propose that palladin is required for the initiation of neural tube closure and provides an important new candidate that may be implicated in the etiology of human NTDs. | Disruption of palladin results in neural tube closure defects in mice.
Luo H, Liu X, Wang F, Huang Q, Shen S, Wang L, Xu G, Sun X, Kong H, Gu M, Chen S, Chen Z, Wang Z. | 01/21/2010 |
| The actin-associated protein palladin may play an important role in recruiting VASP to sites of actin filament growth, anchorage, and crosslinking. | Palladin is a novel binding partner for Ena/VASP family members.
Boukhelifa M, Parast MM, Bear JE, Gertler FB, Otey CA. | 01/21/2010 |