| Identification of the Thyrotropin-Releasing Hormone (TRH) as a Novel Biomarker in the Prognosis for Acute Myeloid Leukemia. | Identification of the Thyrotropin-Releasing Hormone (TRH) as a Novel Biomarker in the Prognosis for Acute Myeloid Leukemia.
Gao Y, Zhou JF, Mao JY, Jiang L, Li XP., Free PMC Article | 11/5/2022 |
| Is the link between elevated TSH and gestational diabetes mellitus dependant on diagnostic criteria and thyroid antibody status: a systematic review and meta-analysis. | Is the link between elevated TSH and gestational diabetes mellitus dependant on diagnostic criteria and thyroid antibody status: a systematic review and meta-analysis.
Kent NL, Young SL, Akison LK, Cuffe JSM. | 10/30/2021 |
| cg01009664 of TRH as a potential biomarker for oral squamous cell carcinoma and oropharyngeal squamous cell carcinoma. | TRH site-specific methylation in oral and oropharyngeal squamous cell carcinoma.
Puttipanyalears C, Arayataweegool A, Chalertpet K, Rattanachayoto P, Mahattanasakul P, Tangjaturonsasme N, Kerekhanjanarong V, Mutirangura A, Kitkumthorn N., Free PMC Article | 01/12/2019 |
| TRH rs13097335 may have a protective role toward the development of breast cancer. | Biased paternal transmission of TRH variant to female Down syndrome probands: possible correlation with low breast cancer frequency.
Dey A, Chatterjee A, Maiti A, Mukherjee N, Sinha S, Panda CK, Mukhopadhyay K. | 11/28/2015 |
| Data indicate that decrease of cholesterol level impaired the functional coupling between the thyrotropin-releasing hormone receptor and the cognate G proteins. | TRH-receptor mobility and function in intact and cholesterol-depleted plasma membrane of HEK293 cells stably expressing TRH-R-eGFP.
Brejchová J, Sýkora J, Ostašov P, Merta L, Roubalová L, Janáček J, Hof M, Svoboda P. | 10/3/2015 |
| TRH, LH-RH and substance P are not affected in Alzheimer disease and Down's syndrome. | Thyrotropin-releasing hormone, luteinizing hormone-releasing hormone and substance P immuno-reactivity in post-mortem brain from cases of Alzheimer-type dementia and Down's syndrome.
Yates CM, Harmar AJ, Rosie R, Sheward J, de Levy GS, Simpson J, Maloney AF, Gordon A, Fink G. | 10/26/2013 |
| Cpe mutations in mouse may affect processing of prothyrotropin releasing hormone into thyrotropin releasing hormone. | Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice.
Nillni EA, Xie W, Mulcahy L, Sanchez VC, Wetsel WC. | 04/30/2013 |
| TRH inhibits melanin-concentrating hormone (MCH) neurons by increasing synaptic inhibition from local GABA neurons. | Thyrotropin-releasing hormone (TRH) inhibits melanin-concentrating hormone neurons: implications for TRH-mediated anorexic and arousal actions.
Zhang X, van den Pol AN., Free PMC Article | 04/21/2012 |
| This study introduces TRH as a novel, potent, selective, and evolutionarily highly conserved neuroendocrine factor controlling human pigmentation in situ. | Thyrotropin-releasing hormone selectively stimulates human hair follicle pigmentation.
Gáspár E, Nguyen-Thi KT, Hardenbicker C, Tiede S, Plate C, Bodó E, Knuever J, Funk W, Bíró T, Paus R. | 01/14/2012 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Case Report: Isolated idiopathic central hypothyroidism in an adult, possibly caused by thyrotropin releasing hormone (TRH) deficiency. | Isolated idiopathic central hypothyroidism in an adult, possibly caused by thyrotropin releasing hormone (TRH) deficiency.
Prieto-Tenreiro A, Diaz-Guardiola P. | 08/30/2010 |
| Thus, human scalp hair follicles are both a source and a target of TRH, which operates as a potent hair-growth stimulator | Thyrotropin releasing hormone (TRH): a new player in human hair-growth control.
Gáspár E, Hardenbicker C, Bodó E, Wenzel B, Ramot Y, Funk W, Kromminga A, Paus R. | 03/1/2010 |
| study shows: negative regulation of TRH gene by TH involves acetylation & methylation of specific residues of histone tails & changing amount of TR; impairment to histone modifications in TR mutant F455S was hyperacetylation of specific histone tails | Aberrant histone modifications at the thyrotropin-releasing hormone gene in resistance to thyroid hormone: analysis of F455S mutant thyroid hormone receptor.
Umezawa R, Yamada M, Horiguchi K, Ishii S, Hashimoto K, Okada S, Satoh T, Mori M., Free PMC Article | 01/21/2010 |
| Our results support the hypothesis that patients with pseudohypoparathyroidism Ia have impaired sensitivity to both TSH and TRH. | Hypothyroidism in patients with pseudohypoparathyroidism type Ia: clinical evidence of resistance to TSH and TRH.
Balavoine AS, Ladsous M, Velayoudom FL, Vlaeminck V, Cardot-Bauters C, d'Herbomez M, Wemeau JL. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (6) articlesAssociation study of 182 candidate genes in anorexia nervosa.
Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB. Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.
Saus E, Brunet A, Armengol L, Alonso P, Crespo JM, Fernández-Aranda F, Guitart M, Martín-Santos R, Menchón JM, Navinés R, Soria V, Torrens M, Urretavizcaya M, Vallès V, Gratacòs M, Estivill X. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.
Yerges LM, Klei L, Cauley JA, Roeder K, Kammerer CM, Moffett SP, Ensrud KE, Nestlerode CS, Marshall LM, Hoffman AR, Lewis C, Lang TF, Barrett-Connor E, Ferrell RE, Orwoll ES, Zmuda JM, MrOS Research Group. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group. Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension.
Kokubo Y, Tomoike H, Tanaka C, Banno M, Okuda T, Inamoto N, Kamide K, Kawano Y, Miyata T. | 03/13/2008 |
| The presence of TRH in dysplastic nevi may be predictive for the development of melanoma. | Expression of thyrotropin-releasing hormone by human melanoma and nevi.
Ellerhorst JA, Naderi AA, Johnson MK, Pelletier P, Prieto VG, Diwan AH, Johnson MM, Gunn DC, Yekell S, Grimm EA. | 01/21/2010 |
| results show that that leptin can regulate trh gene expression via activation of intracellular signal transducer and activator of transcription 3 (STAT3) proteins in TRH neurons in the hypothalamus | Role of signal transducer and activator of transcription 3 in regulation of hypothalamic trh gene expression by leptin.
Huo L, Münzberg H, Nillni EA, Bjørbaek C. | 01/21/2010 |
| TRH mRNA levels in "mute" thyrotropinomas: cause-effect or coincidence? | TRH synthesis in "mute" thyrotropinomas: cause-effect or coincidence?
Badiu C, Ham J, Carnu R, Coculescu M., Free PMC Article | 01/21/2010 |