| Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPARgamma. | Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPARγ.
Cheng WL, Chao SP, Zhao F, Cai HH, Zeng Z, Cao JL, Jin Z, Deng KQ, Hu X, Wang H, Lu Z. | 05/28/2024 |
| Silencing of TRAF5 enhances necroptosis in hepatocellular carcinoma by inhibiting LTBR-mediated NF-kappaB signaling. | Silencing of TRAF5 enhances necroptosis in hepatocellular carcinoma by inhibiting LTBR-mediated NF-κB signaling.
Wu G, Wu F, Zhou YQ, Lu W, Hu FL, Fan X., Free PMC Article | 07/5/2023 |
| LncRNA HCG18 upregulates TRAF4/TRAF5 to facilitate proliferation, migration and EMT of epithelial ovarian cancer by targeting miR-29a/b. | LncRNA HCG18 upregulates TRAF4/TRAF5 to facilitate proliferation, migration and EMT of epithelial ovarian cancer by targeting miR-29a/b.
Zhang F, Luo BH, Wu QH, Li QL, Yang KD., Free PMC Article | 04/2/2022 |
| Association of methylation level and transcript level in TRAF5 gene with ankylosing spondylitis: a case-control study. | Association of methylation level and transcript level in TRAF5 gene with ankylosing spondylitis: a case-control study.
Xu S, Gao X, Ma Y, Deng J, Xu S, Pan F. | 01/22/2022 |
| Single nucleotide polymorphisms of TRAF2 and TRAF5 gene in ankylosing spondylitis: a case-control study. | Single nucleotide polymorphisms of TRAF2 and TRAF5 gene in ankylosing spondylitis: a case-control study.
Xu S, Kong J, Huang L, Xie H, Wang F, Zhou T, Zhang X, Yu L, Xu S, Pan F. | 01/22/2022 |
| Tumor-Associated Macrophages Promote Oxaliplatin Resistance via METTL3-Mediated m(6)A of TRAF5 and Necroptosis in Colorectal Cancer. | Tumor-Associated Macrophages Promote Oxaliplatin Resistance via METTL3-Mediated m(6)A of TRAF5 and Necroptosis in Colorectal Cancer.
Lan H, Liu Y, Liu J, Wang X, Guan Z, Du J, Jin K. | 11/6/2021 |
| Down-regulated HDAC3 elevates microRNA-495-3p to restrain epithelial-mesenchymal transition and oncogenicity of melanoma cells via reducing TRAF5. | Down-regulated HDAC3 elevates microRNA-495-3p to restrain epithelial-mesenchymal transition and oncogenicity of melanoma cells via reducing TRAF5.
Ma Y, Duan J, Hao X., Free PMC Article | 06/19/2021 |
| LINC00467 promotes cell proliferation and metastasis by binding with IGF2BP3 to enhance the mRNA stability of TRAF5 in hepatocellular carcinoma. | LINC00467 promotes cell proliferation and metastasis by binding with IGF2BP3 to enhance the mRNA stability of TRAF5 in hepatocellular carcinoma.
Jiang W, Cheng X, Wang T, Song X, Zheng Y, Wang L. | 06/5/2021 |
| TRAF5 promotes the occurrence and development of colon cancer via the activation of PI3K/AKT/NF-kappaB signaling pathways. | TRAF5 promotes the occurrence and development of colon cancer via the activation of PI3K/AKT/NF-κB signaling pathways.
Sun G, Zheng C, Deng Z, Huang C, Huang J. | 11/21/2020 |
| Overexpression of miRNA-410-3p protects hypoxia-induced cardiomyocyte injury via targeting TRAF5. | Overexpression of miRNA-410-3p protects hypoxia-induced cardiomyocyte injury via targeting TRAF5.
Teng YL, Ren F, Xu H, Song HJ. | 10/24/2020 |
| miR-141-3p and TRAF5 Network Contributes to the Progression of T-Cell Acute Lymphoblastic Leukemia. | miR-141-3p and TRAF5 Network Contributes to the Progression of T-Cell Acute Lymphoblastic Leukemia.
Zhou R, Mo W, Wang S, Zhou W, Chen X, Pan S., Free PMC Article | 09/19/2020 |
| TRAF5 acts as a positive regulator of plasmacytoid DCs differentiation from bone marrow progenitors. | TRAF5 promotes plasmacytoid dendritic cell development from bone marrow progenitors.
Kobayashi S, Shiota Y, Kawabe T, Phung HT, Maruyama T, Owada Y, So T, Ishii N. | 08/1/2020 |
| miR-141-3p inhibited the proliferation, migration, and invasion via directly targeting tumor necrosis factor receptor-associated factor 5 (TRAF5). | MiR-141-3p inhibits cell proliferation, migration and invasion by targeting TRAF5 in colorectal cancer.
Liang Z, Li X, Liu S, Li C, Wang X, Xing J. | 06/20/2020 |
| The study highlights the importance of miR-135a-5p and TRAF5 in gliomagenesis and progression and implies their potential prognostic and therapeutic values in malignant glioma. | miR-135a-5p Functions as a Glioma Proliferation Suppressor by Targeting Tumor Necrosis Factor Receptor-Associated Factor 5 and Predicts Patients' Prognosis.
Luo W, Sun C, Zhou J, Wang Q, Yu L, Bian XW, Zhou X, Hua D, Wang R, Rao C, Jiang Z, Shi C, Yu S. | 10/26/2019 |
| These findings suggest that upregulation of miR-29b-3p could protect cardiomyocytes against hypoxia-induced injury through downregulation of TRAF5. | Upregulation of miR-29b-3p protects cardiomyocytes from hypoxia-induced apoptosis by targeting TRAF5.
Cai Y, Li Y., Free PMC Article | 05/18/2019 |
| High TRAF5 expression is associated with colorectal cancer. | miR‑873 inhibits colorectal cancer cell proliferation by targeting TRAF5 and TAB1.
Gong H, Fang L, Li Y, Du J, Zhou B, Wang X, Zhou H, Gao L, Wang K, Zhang J., Free PMC Article | 09/1/2018 |
| Study presents the characterization of the peptide binding preferences of TRAFs 2, 3, and 5 using deep mutational scanning. The three TRAF proteins demonstrated different preferences for binding to members of the CD40 library, and three peptides from that library individually showed striking differences in affinity for the three TRAFs. | Comparison of the peptide binding preferences of three closely related TRAF paralogs: TRAF2, TRAF3, and TRAF5.
Foight GW, Keating AE., Free PMC Article | 04/29/2017 |
| These findings indicate that miR-26b might influence TRAF5-MAPK signaling pathways to facilitate the malignant progression of melanoma cells. | MiR-26b inhibits melanoma cell proliferation and enhances apoptosis by suppressing TRAF5-mediated MAPK activation.
Li M, Long C, Yang G, Luo Y, Du H. | 07/16/2016 |
| findings reveal a direct link between TRAF5-mediated ubiquitination and RORgammat protein regulation | TRAF5-mediated Lys-63-linked Polyubiquitination Plays an Essential Role in Positive Regulation of RORγt in Promoting IL-17A Expression.
Wang X, Yang J, Han L, Zhao K, Wu Q, Bao L, Li Z, Lv L, Li B., Free PMC Article | 03/19/2016 |
| RIG-I-like receptor mediated antiviral innate immune responses in the lower respiratory tract involves TRAF3 and TRAF5 signaling. | Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5.
Chiba Y, Matsumiya T, Satoh T, Hayakari R, Furudate K, Xing F, Yoshida H, Tanji K, Mizukami H, Imaizumi T, Ito E. | 02/6/2016 |
| This study provides evidence that TRAF5 and TRAF3IP2 genes are involved in the development of Behcet's disease (BD) and Vogt-Koyanagi-Harada (VKH) syndrome. | TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behçet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
Xiang Q, Chen L, Hou S, Fang J, Zhou Y, Bai L, Liu Y, Kijlstra A, Yang P., Free PMC Article | 09/13/2014 |
| Data indicate that TNF receptor-associated factor 5 (TRAF5) gene is involved in the development of acute anterior uveitis (AAU) and pediatric uveitis. | TNF receptor-associated factor 5 gene confers genetic predisposition to acute anterior uveitis and pediatric uveitis.
Xiang Q, Chen L, Fang J, Hou S, Wei L, Bai L, Liu Y, Zhou Y, Kijlstra A, Yang P., Free PMC Article | 08/9/2014 |
| Data indicate that in monocyte- derived macrophages (MDMs) acutely infected with HIV-1 and treated with HCV rCore and HIV-1 rNef, the HIV-1 replication depends on an upstream signal mediated through TRAF2, TRAF5 and TRAF6. | HIV-1 Nef interacts with HCV Core, recruits TRAF2, TRAF5 and TRAF6, and stimulates HIV-1 replication in macrophages.
Khan KA, Abbas W, Varin A, Kumar A, Di Martino V, Dichamp I, Herbein G., Free PMC Article | 07/5/2014 |
| TRAF3 and TRAF5 are overexpressed in inflammatory bowel disease | Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory bowel disease.
Shen J, Qiao YQ, Ran ZH, Wang TR., Free PMC Article | 07/13/2013 |
| Numbl interacted with tumor necrosis factor receptor-associated factor 5, which signals upstream and is required for the activation of NF-kappaB, and committed it to proteasomal degradation by promoting K48-linked polyubiquitination of TRAF5 | Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation.
Tao T, Cheng C, Ji Y, Xu G, Zhang J, Zhang L, Shen A., Free PMC Article | 12/22/2012 |