| Complement 3a induces the synapse loss via C3aR in mitochondria-dependent NLRP3 activating mechanisms during the development and progression of Alzheimer's disease. | Complement 3a induces the synapse loss via C3aR in mitochondria-dependent NLRP3 activating mechanisms during the development and progression of Alzheimer's disease.
Ge TQ, Guan PP, Wang P. | 09/23/2024 |
| Increased expression of complement C3c, iC3b, and cells containing CD11b or CD14 in experimentally induced psoriatic lesion. | Increased expression of complement C3c, iC3b, and cells containing CD11b or CD14 in experimentally induced psoriatic lesion.
Rahkola D, Harvima RJ, Harvima IT., Free PMC Article | 07/15/2024 |
| Complement decay-accelerating factor inhibits inflammation-induced myopia development. | Complement decay-accelerating factor inhibits inflammation-induced myopia development.
Chou YL, Hsu YA, Lin CF, Chen CS, Tien PT, Wang YC, Chang CY, Lin ES, Chen JJ, Wu MY, Chuang CY, Lin HJ, Wan L. | 06/21/2024 |
| Subsequent correlated changes in complement component 3 and amyloid beta oligomers in the blood of patients with Alzheimer's disease. | Subsequent correlated changes in complement component 3 and amyloid beta oligomers in the blood of patients with Alzheimer's disease.
Shim KH, Kim D, Kang MJ, Pyun JM, Park YH, Youn YC, Park KW, Suk K, Lee HW, Gomes BF, Zetterberg H, An SSA, Kim S, Alzheimer's Disease All Markers (ADAM) Research group., Free PMC Article | 04/30/2024 |
| Defective C3d caused by C3 p.W1034R in inherited atypical hemolytic uremic syndrome. | Defective C3d caused by C3 p.W1034R in inherited atypical hemolytic uremic syndrome.
Tsuchida M, Goto S, Watanabe H, Goto S, Yamaguchi H, Narita I., Free PMC Article | 02/7/2024 |
| HylS', a fragment of truncated hyaluronidase of Streptococcus suis, contributes to immune evasion by interaction with host complement factor C3b. | HylS', a fragment of truncated hyaluronidase of Streptococcus suis, contributes to immune evasion by interaction with host complement factor C3b.
Xu J, Chen L, Pang S, Zhang Q, Deng S, Zhu J, Chen X, Langford PR, Huang Q, Zhou R, Li L., Free PMC Article | 02/6/2024 |
| Serum Uric Acid Associates with Systemic Complement C3 Activation in Severe ANCA-Associated Renal Vasculitides. | Serum Uric Acid Associates with Systemic Complement C3 Activation in Severe ANCA-Associated Renal Vasculitides.
Baier E, Kluge IA, Hakroush S, Korsten P, Tampe B., Free PMC Article | 01/31/2024 |
| Complement C3 as a potential drug target in periodontitis: Evidence from the cis-Mendelian randomization approach. | Complement C3 as a potential drug target in periodontitis: Evidence from the cis-Mendelian randomization approach.
Alayash Z, Baumeister SE, Holtfreter B, Kocher T, Baurecht H, Ehmke B, Nolde M, Reckelkamm SL. | 01/29/2024 |
| Trypanosoma brucei Invariant Surface gp65 Inhibits the Alternative Pathway of Complement by Accelerating C3b Degradation. | Trypanosoma brucei Invariant Surface gp65 Inhibits the Alternative Pathway of Complement by Accelerating C3b Degradation.
Lorentzen J, Olesen HG, Hansen AG, Thiel S, Birkelund S, Andersen CBF, Andersen GR. | 08/25/2023 |
| Serum complement component 3, complement component 4 and complement component 1q levels predict progressive visual field loss in older women with primary angle closure glaucoma. | Serum complement component 3, complement component 4 and complement component 1q levels predict progressive visual field loss in older women with primary angle closure glaucoma.
Li S, Qiu Y, Yu J, Shao M, Li Y, Cao W, Sun X. | 06/23/2023 |
| Roles of mesangial C3 and C1q deposition in the clinical manifestations and prognosis of IgAN. | Roles of mesangial C3 and C1q deposition in the clinical manifestations and prognosis of IgAN.
Wang S, Dong L, Qin A, Tan J, Zhou X, Qin W. | 06/19/2023 |
| Complement protein C3a enhances adaptive immune responses towards FVIII products. | Complement protein C3a enhances adaptive immune responses towards FVIII products.
Ringler E, Iannazzo SO, Herzig J, Weiss LM, Anzaghe M, Miller L, Waibler Z., Free PMC Article | 06/13/2023 |
| Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction. | Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
Sülzen H, Began J, Dhillon A, Kereïche S, Pompach P, Votrubova J, Zahedifard F, Šubrtova A, Šafner M, Hubalek M, Thompson M, Zoltner M, Zoll S., Free PMC Article | 05/8/2023 |
| Association of Complement C3 With Incident Type 2 Diabetes and the Mediating Role of BMI: A 10-Year Follow-Up Study. | Association of Complement C3 With Incident Type 2 Diabetes and the Mediating Role of BMI: A 10-Year Follow-Up Study.
Jiang J, Wang H, Liu K, He S, Li Z, Yuan Y, Yu K, Long P, Wang J, Diao T, Zhang X, He M, Guo H, Wu T. | 03/10/2023 |
| Targeted genotyping of COVID-19 patients reveals a signature of complement C3 and factor B coding SNPs associated with severe infection. | Targeted genotyping of COVID-19 patients reveals a signature of complement C3 and factor B coding SNPs associated with severe infection.
Tsiftsoglou SA, Gavriilaki E, Touloumenidou T, Koravou EE, Koutra M, Papayanni PG, Karali V, Papalexandri A, Varelas C, Chatzopoulou F, Chatzidimitriou M, Chatzidimitriou D, Veleni A, Rapti E, Kioumis I, Kaimakamis E, Bitzani M, Boumpas DT, Tsantes A, Sotiropoulos D, Papadopoulou A, Sakellari I, Kokoris S, Anagnostopoulos A., Free PMC Article | 03/8/2023 |
| A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration. | A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration.
Hallam TM, Cox TE, Smith-Jackson K, Brocklebank V, Baral AJ, Tzoumas N, Steel DH, Wong EKS, Shuttleworth VG, Lotery AJ, Harris CL, Marchbank KJ, Kavanagh D., Free PMC Article | 01/21/2023 |
| Complement component 3 protects human bronchial epithelial cells from cigarette smoke-induced oxidative stress and prevents incessant apoptosis. | Complement component 3 protects human bronchial epithelial cells from cigarette smoke-induced oxidative stress and prevents incessant apoptosis.
Pei Y, Zhang J, Qu J, Rao Y, Li D, Gai X, Chen Y, Liang Y, Sun Y., Free PMC Article | 01/14/2023 |
| Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood. | Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood.
Landsem A, Emblem Å, Lau C, Christiansen D, Gerogianni A, Karlsen BO, Mollnes TE, Nilsson PH, Brekke OL., Free PMC Article | 01/14/2023 |
| Implication of platelets and complement C3 as link between innate immunity and tubulointerstitial injury in renal vasculitis with MPO-ANCA seropositivity. | Implication of platelets and complement C3 as link between innate immunity and tubulointerstitial injury in renal vasculitis with MPO-ANCA seropositivity.
Baier E, Tampe D, Kluge IA, Hakroush S, Tampe B., Free PMC Article | 12/3/2022 |
| Complement 3 Is a Potential Biomarker for Cerebral Amyloid Angiopathy. | Complement 3 Is a Potential Biomarker for Cerebral Amyloid Angiopathy.
Saito S, Yamashiro T, Yamauchi M, Yamamoto Y, Noguchi M, Tomita T, Kawakami D, Shikata M, Tanaka T, Ihara M. | 09/17/2022 |
| Association between peripheral blood WBCs C3aR mRNA level and plasma C3a, C3aR, IL-1beta concentrations and acute exacerbation of chronic obstructive pulmonary disease. | Association between peripheral blood WBCs C3aR mRNA level and plasma C3a, C3aR, IL-1β concentrations and acute exacerbation of chronic obstructive pulmonary disease.
Li Z, He P, Ding H, Gong L, Wu J, Zhong C, Liu D. | 07/30/2022 |
| Human Melanoma-Associated Mast Cells Display a Distinct Transcriptional Signature Characterized by an Upregulation of the Complement Component 3 That Correlates With Poor Prognosis. | Human Melanoma-Associated Mast Cells Display a Distinct Transcriptional Signature Characterized by an Upregulation of the Complement Component 3 That Correlates With Poor Prognosis.
Bahri R, Kiss O, Prise I, Garcia-Rodriguez KM, Atmoko H, Martínez-Gómez JM, Levesque MP, Dummer R, Smith MP, Wellbrock C, Bulfone-Paus S., Free PMC Article | 06/18/2022 |
| Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology. | Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology.
Jiao Y, Jiang S, Wang Y, Yu T, Zou G, Zhuo L, Li W., Free PMC Article | 05/21/2022 |
| Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia. | Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia.
Raballah E, Anyona SB, Cheng Q, Munde EO, Hurwitz IF, Onyango C, Ndege C, Hengartner NW, Pacheco MA, Escalante AA, Lambert CG, Ouma C, Obama HCJT, Schneider KA, Seidenberg PD, McMahon BH, Perkins DJ., Free PMC Article | 05/7/2022 |
| Fibrogenesis Marker PRO-C3 Is Higher in Advanced Liver Fibrosis and Improves in Patients Undergoing Bariatric Surgery. | Fibrogenesis Marker PRO-C3 Is Higher in Advanced Liver Fibrosis and Improves in Patients Undergoing Bariatric Surgery.
Bel Lassen P, Nori N, Bedossa P, Genser L, Aron-Wisnewsky J, Poitou C, Surabattula R, Juul Nielsen M, Asser Karsdal M, Julie Leeming D, Schuppan D, Clément K. | 04/23/2022 |