U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    TLR1 toll like receptor 1 [ Homo sapiens (human) ]

    Gene ID: 7096, updated on 12-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Investigation of the association between the Toll-like receptor 1 rs4833095 variation and gastric adenocarcinoma recurrence.

    Investigation of the association between the Toll-like receptor 1 rs4833095 variation and gastric adenocarcinoma recurrence.
    Dang Y, Huang J, Lin C, Xu S.

    11/5/2024
    Correlation of polymorphism in Toll-Like Receptor (TLR1 and TLR2) genes with susceptibility of pulmonary tuberculosis in Doda region of India.

    Correlation of polymorphism in Toll-Like Receptor (TLR1 and TLR2) genes with susceptibility of pulmonary tuberculosis in Doda region of India.
    Zargar AS, Borole K, Rai R.

    02/20/2024
    A novel missense compound heterozygous variant in TLR1 gene is associated with susceptibility to rheumatoid arthritis - structural perspective and functional annotations.

    A novel missense compound heterozygous variant in TLR1 gene is associated with susceptibility to rheumatoid arthritis - structural perspective and functional annotations.
    Pasha U, Hanif K, Nisar H, Abid R, Mirza MU, Wajid B, Sadaf S.

    02/6/2024
    Toll-Like Receptor 1 Locus Re-examined in a Genome-Wide Association Study Update on Anti-Helicobacter pylori IgG Titers.

    Toll-Like Receptor 1 Locus Re-examined in a Genome-Wide Association Study Update on Anti-Helicobacter pylori IgG Titers.
    Lam SY, Mommersteeg MC, Yu B, Broer L, Spaander MCW, Frost F, Weiss S, Völzke H, Lerch MM, Schöttker B, Zhang Y, Stocker H, Brenner H, Levy D, Hwang SJ, Wood AC, Rich SS, Rotter JI, Taylor KD, Tracy RP, Kabagambe EK, Leja M, Klovins J, Peculis R, Rudzite D, Nikitina-Zake L, Skenders G, Rovite V, Uitterlinden A, Kuipers EJ, Fuhler GM, Homuth G, Peppelenbosch MP.

    05/7/2022
    Landscape of Cell Communication in Human Dental Pulp.

    Landscape of Cell Communication in Human Dental Pulp.
    Yin W, Liu G, Li J, Bian Z.

    03/26/2022
    Are Pattern Recognition Receptors Associated with Hepatocellular Carcinoma?

    Are Pattern Recognition Receptors Associated with Hepatocellular Carcinoma?
    Dertli R, Asil M, Bıyık M, Karakarcayıldız A, Keskin M, Kayar Y, Başdemirci M, Ataseven H., Free PMC Article

    01/22/2022
    Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn(2+) ions.

    Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn(2+) ions.
    Lushpa VA, Goncharuk MV, Lin C, Zalevsky AO, Talyzina IA, Luginina AP, Vakhrameev DD, Shevtsov MB, Goncharuk SA, Arseniev AS, Borshchevskiy VI, Wang X, Mineev KS., Free PMC Article

    12/11/2021
    Toll-like receptor 1 as a possible target in non-alcoholic fatty liver disease.

    Toll-like receptor 1 as a possible target in non-alcoholic fatty liver disease.
    Baumann A, Nier A, Hernández-Arriaga A, Brandt A, Lorenzo Pisarello MJ, Jin CJ, Pilar E, Camarinha-Silva A, Schattenberg JM, Bergheim I., Free PMC Article

    11/13/2021
    Association of Immune and Inflammatory Gene Polymorphism With the Risk of IgA Nephropathy: A Systematic Review and Meta-Analysis of 45 Studies.

    Association of Immune and Inflammatory Gene Polymorphism With the Risk of IgA Nephropathy: A Systematic Review and Meta-Analysis of 45 Studies.
    Ding X, Mei Y, Mao Z, Long L, Han Q, You Y, Zhu H., Free PMC Article

    10/30/2021
    Altered tonsillar toll-like receptor (TLR)-1 and TLR-2 expression levels between periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), and group A beta-hemolytic streptococcal (GAbetaHS) recurrent tonsillitis patients.

    Altered tonsillar toll-like receptor (TLR)-1 and TLR-2 expression levels between periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA), and group A beta-hemolytic streptococcal (GAβHS) recurrent tonsillitis patients.
    Gazi U, Ozkayalar H, Mujahed MIM, Tosun O, Dalkan C, Sanlidag B, Asım Safak M, Mocan G, Onder Bahceciler N.

    09/4/2021
    Toll-like receptor 1 and 10 variations increase asthma risk and review highlights further research directions.

    Toll-like receptor 1 and 10 variations increase asthma risk and review highlights further research directions.
    Korppi M, Törmänen S.

    09/5/2020
    Toll-like receptor 1 may have a role in favorable prognosis in pancreatic cancer

    Toll-like receptor 1 predicts favorable prognosis in pancreatic cancer.
    Lanki M, Seppänen H, Mustonen H, Hagström J, Haglund C., Free PMC Article

    03/14/2020
    we also investigated the association of breastfeeding duration with DNA methylation at two sites in the promoter of the toll-like receptor-1 (TLR1) gene, as well as the association between DNA methylation of the toll-like receptor-1 (TLR1) gene and susceptibility to different diseases.

    Association of Breastfeeding Duration with Susceptibility to Allergy, Influenza, and Methylation Status of TLR1 Gene.
    Hatmal MM, Issa NN, Alshaer W, Al-Ameer HJ, Abuyaman O, Tayyem R, Hijjawi NS., Free PMC Article

    02/29/2020
    Authors demonstrated that these differences relied on diverse signaling pathways activated by TLR1/2. MAPK and NF-kappaB pathways were engaged by TLR1, whereas the Phosphoinositide 3-kinase (PI3K) pathway was activated by TLR2.

    TLR1/2 orchestrate human plasmacytoid predendritic cell response to gram+ bacteria.
    Raieli S, Trichot C, Korniotis S, Pattarini L, Soumelis V., Free PMC Article

    01/11/2020
    association of rs5743618 with BCG osteitis not found

    Toll-like receptor 1, 2 and 6 polymorphisms: no association with 11 serum cytokine concentrations.
    Korppi M, Teräsjärvi J, Vuononvirta J, Liehu-Martiskainen M, Huhtala H, Kröger L, Pöyhönen L, He Q.

    11/30/2019
    Study identifies TLR1 as a gene associated with a severe phenotype of bacteremic melioidosis. The TLR1 variant rs76600635, common in East Asian populations, may be associated with poor outcomes from melioidosis. This variant has not been previously associated with outcomes in sepsis.

    Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis.
    Wright SW, Emond MJ, Lovelace-Macon L, Ducken D, Kashima J, Hantrakun V, Chierakul W, Teparrukkul P, Chantratita N, Limmathurotsakul D, West TE., Free PMC Article

    07/6/2019
    TLR1 rs4833095 SNP was associated with an increased risk of gastric cancer but not atrophic gastritis in a European population.

    TLR1 and PRKAA1 Gene Polymorphisms in the Development of Atrophic Gastritis and Gastric Cancer.
    Dargiene G, Streleckiene G, Skieceviciene J, Leja M, Link A, Wex T, Kupcinskas L, Malfertheiner P, Kupcinskas J.

    06/29/2019
    Intake of red and processed meat interacted with TLR1, TLR10, so that variant carriers of wild type alleles were at increased risk of colorectal cancer.

    Meat and fiber intake and interaction with pattern recognition receptors (TLR1, TLR2, TLR4, and TLR10) in relation to colorectal cancer in a Danish prospective, case-cohort study.
    Kopp TI, Vogel U, Tjonneland A, Andersen V.

    06/8/2019
    Whole-genome sequencing reveals possible role of deleterious mutation of TLR1 in ossification of the posterior longitudinal ligament of the thoracic spine in the Chinese population.

    Whole-genome sequencing reveals novel genes in ossification of the posterior longitudinal ligament of the thoracic spine in the Chinese population.
    Liang C, Wang P, Liu X, Yang C, Ma Y, Yong L, Zhu B, Liu X, Liu Z., Free PMC Article

    04/13/2019
    Heterozygous genotype of the TLR1 single nucleotide polymorphism rs4833095 showed a statistically significant association with an increased protection from leprosy in Brazilian women.

    The TLR1 gene is associated with higher protection from leprosy in women.
    Alvarenga Niitsuma EN, Fernandes GDR, Lana FCF., Free PMC Article

    04/6/2019
    Studied association of genetic variants of toll like receptor 1 (TLR1) with susceptibility to tuberculosis (TB) in Chinese peopulations; results suggest that SNPs of the TLR1 gene were associated with TB susceptibility in the Chinese Tibetan population.

    Variants of TLR1 associated with tuberculosis susceptibility in the Chinese Tibetan population but not in Han Chinese.
    Zhang M, Tang X, Wang Y, Wu S, Wang M, Liu Q, Sandford AJ, He JQ.

    03/30/2019
    Study findings suggest that TLR1 rs4833095 and TLR10 rs10004195 may play crucial roles in H. pylori susceptibility and gastric pathogenesis in the Thai population.

    Genetic polymorphisms in TLR1, TLR2, TLR4, and TLR10 of Helicobacter pylori-associated gastritis: a prospective cross-sectional study in Thailand.
    Tongtawee T, Bartpho T, Kaewpitoon S, Kaewpitoon N, Dechsukhum C, Leeanansaksiri W, Loyd RA, Talabnin K, Matrakool L, Panpimanmas S., Free PMC Article

    02/23/2019
    mean proportions of European ancestry differed significantly between the genotypes of the TLR6 (P249S) gene in a population of the Atlantic Forest, Sao Paulo, Brazil

    Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.
    Guimarães LO, Bajay MM, Monteiro EF, Wunderlich G, Santos SE, Kirchgatter K.

    08/18/2018
    rs5743618 polymorphism increased the the risk of needing inhaled corticosteroids at 11-13 years of age for postbronchiolitis asthma

    Toll-like receptor 1 and 10 gene polymorphisms are linked to postbronchiolitis asthma in adolescence.
    Törmänen S, Korppi M, Lauhkonen E, Koponen P, Teräsjärvi J, Vuononvirta J, Helminen M, He Q, Nuolivirta K.

    07/28/2018
    Suggest that the TLR1 rs4833095 polymorphism may play a role in the development and progression of IgA nephropathy in a Chinese Han population.

    TLR1 polymorphism rs4833095 as a risk factor for IgA nephropathy in a Chinese Han population: A case-control study.
    Gao J, Wei L, Wei J, Yao G, Wang L, Wang M, Liu X, Dai C, Jin T, Dai Z, Fu R., Free PMC Article

    02/24/2018
    firstprevious page of 7 nextlast