| NKX2-1 gene is targeted by H19 lncRNA and is found to be overexpressed in benign nodular goiter tissues. | NKX2-1 gene is targeted by H19 lncRNA and is found to be overexpressed in benign nodular goiter tissues.
Javadirad SM., Free PMC Article | 08/30/2024 |
| NKX2-1 re-expression induces cell death through apoptosis and necrosis in dedifferentiated thyroid carcinoma cells. | NKX2-1 re-expression induces cell death through apoptosis and necrosis in dedifferentiated thyroid carcinoma cells.
Ito Y, Furuya F, Taki K, Suzuki H, Shimura H., Free PMC Article | 07/27/2024 |
| Diagnostic Value of Immunostaining for Thyroid Transcription Factor 1 (TTF1) and Paired Box 8 (PAX8) in Distinguishing Pulmonary Metastases of Mesonephric and Mesonephric-like Adenocarcinomas from Primary Lung Adenocarcinomas. | Diagnostic Value of Immunostaining for Thyroid Transcription Factor 1 (TTF1) and Paired Box 8 (PAX8) in Distinguishing Pulmonary Metastases of Mesonephric and Mesonephric-like Adenocarcinomas from Primary Lung Adenocarcinomas.
Ji N, Lee Y, Lee SH, Kim HS. | 06/5/2024 |
| Functional characterization of two novel NKX2-1 frameshift variants that cause pulmonary surfactant dysfunction. | Functional characterization of two novel NKX2-1 frameshift variants that cause pulmonary surfactant dysfunction.
Wang H, Jiang G, Dai D, Hong D, Zhou W, Qian L. | 03/1/2024 |
| Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer. | Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer.
Heylen E, Verstraete P, Van Aerschot L, Geeraerts SL, Venken T, Timcheva K, Nittner D, Verbeeck J, Royaert J, Gijbels M, Uyttebroeck A, Segers H, Lambrechts D, Cools J, De Keersmaecker K, Kampen KR., Free PMC Article | 05/8/2023 |
| Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma. | Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma.
Ebisudani T, Hamamoto J, Togasaki K, Mitsuishi A, Sugihara K, Shinozaki T, Fukushima T, Kawasaki K, Seino T, Oda M, Hanyu H, Toshimitsu K, Emoto K, Hayashi Y, Asakura K, Johnson TA, Terai H, Ikemura S, Kawada I, Ishii M, Hishida T, Asamura H, Soejima K, Nakagawa H, Fujii M, Fukunaga K, Yasuda H, Sato T. | 04/4/2023 |
| Expression landscapes in non-small cell lung cancer shaped by the thyroid transcription factor 1. | Expression landscapes in non-small cell lung cancer shaped by the thyroid transcription factor 1.
Gloriane C Luna H, Severino Imasa M, Juat N, Hernandez KV, May Sayo T, Cristal-Luna G, Marie Asur-Galang S, Bellengan M, John Duga K, Brian Buenaobra B, De Los Santos MI, Medina D, Samo J, Minerva Literal V, Andrew Bascos N, Sy-Naval S. | 02/24/2023 |
| Exploring the values, preferences, and information needs of patients with NKX2-1-related disorders: A qualitative study protocol. | Exploring the values, preferences, and information needs of patients with NKX2-1-related disorders: A qualitative study protocol.
Martín-Gómez C, Ortigoza-Escobar JD, Nou-Fontanet L, Molina-Linde JM, Bachoud-Lévi AC, Léger J, Blasco-Amaro JA, NKX2-1-Related Disorders Guideline Working Group., Free PMC Article | 02/15/2023 |
| Relationship between brain metastasis and thyroid transcription factor 1. | Relationship between brain metastasis and thyroid transcription factor 1.
Kut E, Menekşe S., Free PMC Article | 02/10/2023 |
| Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer. | Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer.
Kong R, Patel AS, Sato T, Jiang F, Yoo S, Bao L, Sinha A, Tian Y, Fridrikh M, Liu S, Feng J, He X, Jiang J, Ma Y, Grullon K, Yang D, Powell CA, Beasley MB, Zhu J, Snyder EL, Li S, Watanabe H., Free PMC Article | 12/24/2022 |
| Optimized thyroid transcription factor-1 core promoter-driven microRNA-7 expression effectively inhibits the growth of human non-small-cell lung cancer cells. | Optimized thyroid transcription factor-1 core promoter-driven microRNA-7 expression effectively inhibits the growth of human non-small-cell lung cancer cells.
Chen S, Guan L, Zhao X, Yang J, Chen L, Guo M, Zhao J, Chen C, Zhou Y, Han Y, Xu L., Free PMC Article | 12/3/2022 |
| FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma. | FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.
Orstad G, Fort G, Parnell TJ, Jones A, Stubben C, Lohman B, Gillis KL, Orellana W, Tariq R, Klingbeil O, Kaestner K, Vakoc CR, Spike BT, Snyder EL., Free PMC Article | 08/20/2022 |
| Mutational and bioinformatics analysis of the NKX2.1 gene in a cohort of Iranian pediatric patients with congenital hypothyroidism (CH). | Mutational and bioinformatics analysis of the NKX2.1 gene in a cohort of Iranian pediatric patients with congenital hypothyroidism (CH).
Heidari MM, Madani Manshadi SA, Eshghi AR, Talebi F, Khatami M, Bragança J, Ordooei M, Chamani R, Ghasemi F. | 08/6/2022 |
| SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas. | SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas.
Tanaka I, Dayde D, Tai MC, Mori H, Solis LM, Tripathi SC, Fahrmann JF, Unver N, Parhy G, Jain R, Parra ER, Murakami Y, Aguilar-Bonavides C, Mino B, Celiktas M, Dhillon D, Casabar JP, Nakatochi M, Stingo F, Baladandayuthapani V, Wang H, Katayama H, Dennison JB, Lorenzi PL, Do KA, Fujimoto J, Behrens C, Ostrin EJ, Rodriguez-Canales J, Hase T, Fukui T, Kajino T, Kato S, Yatabe Y, Hosoda W, Kawaguchi K, Yokoi K, Chen-Yoshikawa TF, Hasegawa Y, Gazdar AF, Wistuba II, Hanash S, Taguchi A., Free PMC Article | 04/30/2022 |
| Altered pituitary morphology as a sign of benign hereditary chorea caused by TITF1/NKX2.1 mutations. | Altered pituitary morphology as a sign of benign hereditary chorea caused by TITF1/NKX2.1 mutations.
Thust S, Veneziano L, Parkinson MH, Bhatia KP, Mantuano E, Gonzalez-Robles C, Davagnanam I, Giunti P., Free PMC Article | 04/23/2022 |
| Working memory, attention and planning abilities in NKX2.1-related chorea. | Working memory, attention and planning abilities in NKX2.1-related chorea.
Graziola F, Garone G, Grasso M, Schirinzi T, Capuano A. | 02/5/2022 |
| NKX2.1 run-on mutation associated to familial brain-lung-thyroid syndrome. | NKX2.1 run-on mutation associated to familial brain-lung-thyroid syndrome.
Cavaliere E, Gortan AJ, Passon N, Fabbro D, Marin D, Carecchio M, Baldan F, Credendino SC, Gallo R, Cogo P, Damante G, De Vita G., Free PMC Article | 12/25/2021 |
| TTF-1 and c-MYC-defined Phenotypes of Large Cell Neuroendocrine Carcinoma and Delta-like Protein 3 Expression for Treatment Selection. | TTF-1 and c-MYC-defined Phenotypes of Large Cell Neuroendocrine Carcinoma and Delta-like Protein 3 Expression for Treatment Selection.
Miyagawa-Hayashino A, Okada S, Takeda-Miyata N, Takashima Y, Yamada T, Takemura Y, Uchino J, Inoue M, Takayama K, Konishi E., Free PMC Article | 12/25/2021 |
| Deletion of conserved non-coding sequences downstream from NKX2-1: A novel disease-causing mechanism for benign hereditary chorea. | Deletion of conserved non-coding sequences downstream from NKX2-1: A novel disease-causing mechanism for benign hereditary chorea.
Liao J, Coffman KA, Locker J, Padiath QS, Nmezi B, Filipink RA, Hu J, Sathanoori M, Madan-Khetarpal S, McGuire M, Schreiber A, Moran R, Friedman N, Hoffner L, Rajkovic A, Yatsenko SA, Surti U., Free PMC Article | 12/11/2021 |
| Thoracic nuclear protein in testis (NUT) carcinoma: expanded pathological spectrum with expression of thyroid transcription factor-1 and neuroendocrine markers. | Thoracic nuclear protein in testis (NUT) carcinoma: expanded pathological spectrum with expression of thyroid transcription factor-1 and neuroendocrine markers.
Hung YP, Chen AL, Taylor MS, Huynh TG, Kem M, Selig MK, Nielsen GP, Lennerz JK, Azzoli CG, Dagogo-Jack I, Kradin RL, Mino-Kenudson M. | 11/22/2021 |
| SMARCA4 (BRG1) and SMARCB1 (INI1) expression in TTF-1 negative neuroendocrine carcinomas including merkel cell carcinoma. | SMARCA4 (BRG1) and SMARCB1 (INI1) expression in TTF-1 negative neuroendocrine carcinomas including merkel cell carcinoma.
Gandhi JS, Alnoor F, Sadiq Q, Solares J, Gradowski JF. | 11/22/2021 |
| Aberrant expression of thyroid transcription factor-1 in meningeal solitary fibrous tumor/hemangiopericytoma. | Aberrant expression of thyroid transcription factor-1 in meningeal solitary fibrous tumor/hemangiopericytoma.
Wu H, Du J, Li H, Li Y, Zhang W, Zhou W, Wang W. | 09/18/2021 |
| Aberrant TTF-1 Expression in Peripheral T-Cell Lymphomas: A Diagnostic Pitfall. | Aberrant TTF-1 Expression in Peripheral T-Cell Lymphomas: A Diagnostic Pitfall.
Chang ST, Chen SW, Chen BJ, Pan ST, Karube K, Chuang SS. | 08/21/2021 |
| CRISPRi-mediated functional analysis of NKX2-1-binding sites in the lung. | CRISPRi-mediated functional analysis of NKX2-1-binding sites in the lung.
Stuart WD, Fink-Baldauf IM, Tomoshige K, Guo M, Maeda Y., Free PMC Article | 08/14/2021 |
| Programmed death-ligand 1 (PD-L1)/thyroid transcription factor-1 double immunohistochemical staining facilitates scoring of tumor PD-L1 expression in cytopathology specimens from lung adenocarcinoma patients. | Programmed death-ligand 1 (PD-L1)/thyroid transcription factor-1 double immunohistochemical staining facilitates scoring of tumor PD-L1 expression in cytopathology specimens from lung adenocarcinoma patients.
Lin YY, Lin LY, Hang JF, Lin CH, Ho HL, Chou TY. | 08/7/2021 |