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    TIMP2 TIMP metallopeptidase inhibitor 2 [ Homo sapiens (human) ]

    Gene ID: 7077, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis.

    Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis.
    Zhang F, Li J, Xu J, Jiang X, Chen S, Nasser QA., Free PMC Article

    07/8/2024
    Demethylation of TIMP2 and TIMP3 Inhibits Cell Proliferation, Migration, and Invasion in Pituitary Adenomas.

    Demethylation of TIMP2 and TIMP3 Inhibits Cell Proliferation, Migration, and Invasion in Pituitary Adenomas.
    Yang Y, Huang F, Wu X, Huang C, Li Y.

    06/3/2024
    Association of TIMP2 418 G/C and MMP Gene Polymorphism with Risk of Urinary Cancers: Systematic Review and Meta-analysis.

    Association of TIMP2 418 G/C and MMP Gene Polymorphism with Risk of Urinary Cancers: Systematic Review and Meta-analysis.
    Gowtham P, Girigoswami K, Thirumalai A, Harini K, Pallavi P, Girigoswami A.

    04/10/2024
    TIMP2 ameliorates blood-brain barrier disruption in traumatic brain injury by inhibiting Src-dependent VE-cadherin internalization.

    TIMP2 ameliorates blood-brain barrier disruption in traumatic brain injury by inhibiting Src-dependent VE-cadherin internalization.
    Tang J, Kang Y, Zhou Y, Shang N, Li X, Wang H, Lan J, Wang S, Wu L, Peng Y., Free PMC Article

    02/9/2024
    Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity.

    Neuronal TIMP2 regulates hippocampus-dependent plasticity and extracellular matrix complexity.
    Ferreira AC, Hemmer BM, Philippi SM, Grau-Perales AB, Rosenstadt JL, Liu H, Zhu JD, Kareva T, Ahfeldt T, Varghese M, Hof PR, Castellano JM., Free PMC Article

    12/28/2023
    TIMP-2 as a predictive biomarker in 5-Fu-resistant colorectal cancer.

    TIMP-2 as a predictive biomarker in 5-Fu-resistant colorectal cancer.
    Li Y, Xu C, Zhu R, Shen L, Hu G, Tao K, Tao F, Lu Z, Zhang G.

    10/28/2023
    Serum levels of matrix metalloproteinase 2 and its inhibitor after tonic-clonic seizures.

    Serum levels of matrix metalloproteinase 2 and its inhibitor after tonic-clonic seizures.
    Cudna A, Bronisz E, Mirowska-Guzel D, Kurkowska-Jastrzębska I.

    05/8/2023
    The Biology and Function of Tissue Inhibitor of Metalloproteinase 2 in the Lungs.

    The Biology and Function of Tissue Inhibitor of Metalloproteinase 2 in the Lungs.
    Costanzo L, Soto B, Meier R, Geraghty P., Free PMC Article

    01/14/2023
    Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis.

    Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis.
    Chang RM, Fu Y, Zeng J, Zhu XY, Gao Y., Free PMC Article

    12/31/2022
    Effects of TIMP-2 Polymorphisms on Retinopathy of Prematurity Risk, Severity, Recurrence, and Treatment Response.

    Effects of TIMP-2 Polymorphisms on Retinopathy of Prematurity Risk, Severity, Recurrence, and Treatment Response.
    Wu PL, Ling XC, Kang EY, Chen KJ, Wang NK, Liu L, Chen YP, Hwang YS, Lai CC, Yang SF, Wu WC., Free PMC Article

    12/10/2022
    TIMP2 genetic variation rs4789932 may associate with an increased risk of developing acne scarring based on a case-control study of Chinese Han population.

    TIMP2 genetic variation rs4789932 may associate with an increased risk of developing acne scarring based on a case-control study of Chinese Han population.
    Wen X, Du H, Hao X, Zhang H, Guo Y.

    11/5/2022
    The role of tissue inhibitor of metalloproteinases in the aetiology of inguinal and incisional hernias.

    The role of tissue inhibitor of metalloproteinases in the aetiology of inguinal and incisional hernias.
    Durukan U, Agcaoglu O, Ozoran E, Karahan SN, Ozata I, Duzkoylu Y, Pasaoglu E, Aren A., Free PMC Article

    10/15/2022
    TIMP2 is associated with prognosis and immune infiltrates of gastric and colon cancer.

    TIMP2 is associated with prognosis and immune infiltrates of gastric and colon cancer.
    Jian F, Yanhong J, Limeng W, Guoping N, Yiqing T, Hao L, Zhaoji P.

    08/27/2022
    Elevated Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Predict Drug-Induced Acute Kidney Injury.

    Elevated Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Predict Drug-Induced Acute Kidney Injury.
    Akalya K, Murali TM, Vathsala A, Teo BW, Low S, Dharmasegaran D, Koh LP, Bonney GK, Hong WZ, Da Y, Chua HR.

    08/6/2022
    Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction.

    Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction.
    Wang HS, Cho PS, Zhi H, Kostel SA, DiMartino S, Dagher AM, Davis KH, Cabour LD, Shimmel A, Lee J, Froehlich JW, Zurakowski D, Moses MA, Lee RS., Free PMC Article

    07/30/2022
    USP7 inhibits TIMP2 by up-regulating the expression of EZH2 to activate the NF-kappaB/PD-L1 axis to promote the development of cervical cancer.

    USP7 inhibits TIMP2 by up-regulating the expression of EZH2 to activate the NF-κB/PD-L1 axis to promote the development of cervical cancer.
    Li N, Geng F, Liang SM, Qin X.

    06/25/2022
    Perioperative Urinary TIMP-2*IGFBP7 and Acute Kidney Injury: A Systematic Review.

    Perioperative Urinary TIMP-2*IGFBP7 and Acute Kidney Injury: A Systematic Review.
    Ciuca AM, Bolin LP, Horne C.

    06/11/2022
    The Role of Tissue Inhibitor of Metalloproteinase-1 and 2 in Echinococcus granulosus senso lato-Induced Human Hepatic Fibrosis.

    The Role of Tissue Inhibitor of Metalloproteinase-1 and 2 in Echinococcus granulosus senso lato-Induced Human Hepatic Fibrosis.
    Hasanzadeh A, Rafiei A, Kazemi M, Beiromvand M, Bahreini A, Khanahmad H.

    05/28/2022
    TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.

    TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
    Miao J, Zhao C, Tang K, Xiong X, Wu F, Xue W, Duan B, Zhang H, Jing X, Li W, Sun Y, Hou N, Huang C., Free PMC Article

    04/23/2022
    Genetic variants of tissue inhibitors of matrix metalloproteinase 1 (rs4898) and 2 (rs8179090) in diverticulosis.

    Genetic variants of tissue inhibitors of matrix metalloproteinase 1 (rs4898) and 2 (rs8179090) in diverticulosis.
    Nehring P, Gromadzka G, Giermaziak A, Jastrzębski M, Przybyłkowski A.

    04/23/2022
    [Advances in the clinical value of tissue inhibitors of metalloproteinase-2 and insulin-like growth factor binding protein 7 in sepsis associated-acute kidney injury].

    [Advances in the clinical value of tissue inhibitors of metalloproteinase-2 and insulin-like growth factor binding protein 7 in sepsis associated-acute kidney injury].
    Jiang W, Zheng R.

    03/26/2022
    Evaluating TIMP-2 and IGFBP-7 as a predictive tool for kidney injury in ureteropelvic junction obstruction.

    Evaluating TIMP-2 and IGFBP-7 as a predictive tool for kidney injury in ureteropelvic junction obstruction.
    Mello MF, de Bessa J Júnior, Reis ST, Kondo EY, Yu L, Dénes FT, Lopes RI., Free PMC Article

    03/26/2022
    Prevention of cardiac surgery-associated acute kidney injury by risk stratification using (TIMP-2)*(IGFBP7).

    Prevention of cardiac surgery-associated acute kidney injury by risk stratification using (TIMP-2)*(IGFBP7).
    Couturier C, Maillard N, Mariat C, Morel J, Palao JC, Bouchet JB, Claisse G.

    03/19/2022
    MiR-149-3p promotes the cisplatin resistance and EMT in ovarian cancer through downregulating TIMP2 and CDKN1A.

    MiR-149-3p promotes the cisplatin resistance and EMT in ovarian cancer through downregulating TIMP2 and CDKN1A.
    Wang J, Liu L., Free PMC Article

    02/19/2022
    Relationships between Circulating Matrix Metalloproteinases, Tissue Inhibitor TIMP-2, and Renal Function in Patients with Myocarditis.

    Relationships between Circulating Matrix Metalloproteinases, Tissue Inhibitor TIMP-2, and Renal Function in Patients with Myocarditis.
    Kobusiak-Prokopowicz M, Kaaz K, Marciniak D, Karolko B, Mysiak A.

    02/5/2022
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