| Defining the landscape of TIA1 and SQSTM1 digenic myopathy. | Defining the landscape of TIA1 and SQSTM1 digenic myopathy.
Panos-Basterra P, Theuriet J, Nadaj-Pakleza A, Magot A, Lannes B, Marcorelles P, Behin A, Masingue M, Caillon F, Malek Y, Fenouil T, Bas J, Menassa R, Michel-Calemard L, Streichenberger N, Simon JP, Bouhour F, Evangelista T, Métay C, Pegat A, Stojkovic T, Fernández-Eulate G. | 09/5/2024 |
| The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics. | The miR-30-5p/TIA-1 axis directs cellular senescence by regulating mitochondrial dynamics.
Tak H, Cha S, Hong Y, Jung M, Ryu S, Han S, Jeong SM, Kim W, Lee EK., Free PMC Article | 06/20/2024 |
| RAMP2-AS1 stabilized RAPM2 mRNA through TIA1 to inhibit the progression of non-small cell lung cancer. | RAMP2-AS1 stabilized RAPM2 mRNA through TIA1 to inhibit the progression of non-small cell lung cancer.
Wang S, Xu C, Shan Y, Zhang Y. | 02/1/2024 |
| Distal myopathy due to digenic inheritance of TIA1 and SQSTM1 variants in two unrelated Spanish patients. | Distal myopathy due to digenic inheritance of TIA1 and SQSTM1 variants in two unrelated Spanish patients.
Bermejo-Guerrero L, de Fuenmayor Fernández-de la Hoz CP, González-Quereda L, Segarra-Casas A, Nedkova V, Gallano P, Martín-Jiménez P, Hernández-Laín A, Olivé M, Arteche-López A, Domínguez-González C. | 12/21/2023 |
| Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein. | Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein.
Zhang D, Qiao L, Lei X, Dong X, Tong Y, Wang J, Wang Z, Zhou R., Free PMC Article | 06/28/2023 |
| The role of peritumoral CD8 + /TIA1 + lymphocytes in hepatocellular carcinoma aggressiveness and recurrence after surgical resection. | The role of peritumoral CD8 + /TIA1 + lymphocytes in hepatocellular carcinoma aggressiveness and recurrence after surgical resection.
Bertuzzi C, Germinario G, Righi S, Ravaioli M, Agostinelli C, Pession A, D'Errico A, Sabattini E, Vasuri F. | 10/29/2022 |
| ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures. | ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures.
Sekiyama N, Takaba K, Maki-Yonekura S, Akagi KI, Ohtani Y, Imamura K, Terakawa T, Yamashita K, Inaoka D, Yonekura K, Kodama TS, Tochio H., Free PMC Article | 10/1/2022 |
| Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling. | Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling.
Li MZ, Liu EJ, Zhou QZ, Li SH, Liu SJ, Yu HT, Pan QH, Sun F, He T, Wang WJ, Ke D, Feng YQ, Li J, Wang JZ., Free PMC Article | 07/16/2022 |
| Amyotrophic lateral sclerosis (ALS) linked mutation in Ubiquilin 2 affects stress granule assembly via TIA-1. | Amyotrophic lateral sclerosis (ALS) linked mutation in Ubiquilin 2 affects stress granule assembly via TIA-1.
Peng G, Gu A, Niu H, Chen L, Chen Y, Zhou M, Zhang Y, Liu J, Cai L, Liang D, Liu X, Liu M., Free PMC Article | 05/14/2022 |
| The Multifunctional Faces of T-Cell Intracellular Antigen 1 in Health and Disease. | The Multifunctional Faces of T-Cell Intracellular Antigen 1 in Health and Disease.
Fernández-Gómez A, Izquierdo JM., Free PMC Article | 04/16/2022 |
| Disease-associated mutations affect TIA1 phase separation and aggregation in a proline-dependent manner. | Disease-associated mutations affect TIA1 phase separation and aggregation in a proline-dependent manner.
Ding X, Gu S, Xue S, Luo SZ. | 03/19/2022 |
| Identification of TIA1 mRNA targets during human neuronal development. | Identification of TIA1 mRNA targets during human neuronal development.
Byres LP, Mufteev M, Yuki KE, Wei W, Piekna A, Wilson MD, Rodrigues DC, Ellis J., Free PMC Article | 01/29/2022 |
| Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1. | Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1.
Loughlin FE, West DL, Gunzburg MJ, Waris S, Crawford SA, Wilce MCJ, Wilce JA., Free PMC Article | 03/27/2021 |
| Typical Stress Granule Proteins Interact with the 3' Untranslated Region of Enterovirus D68 To Inhibit Viral Replication. | Typical Stress Granule Proteins Interact with the 3' Untranslated Region of Enterovirus D68 To Inhibit Viral Replication.
Cheng J, Gao S, Zhu C, Liu S, Li J, Kang J, Wang Z, Wang T., Free PMC Article | 09/19/2020 |
| Single-nucleotide polymorphism in the human TIA1 gene interacts with stressful life events to predict the development of pathological anxiety symptoms in a Swedish population. | Single-nucleotide polymorphism in the human TIA1 gene interacts with stressful life events to predict the development of pathological anxiety symptoms in a Swedish population.
Rayman JB, Melas PA, Schalling M, Forsell Y, Kandel ER, Lavebratt C. | 08/22/2020 |
| identification of a TIA1 variant that drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations | TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.
Lee Y, Jonson PH, Sarparanta J, Palmio J, Sarkar M, Vihola A, Evilä A, Suominen T, Penttilä S, Savarese M, Johari M, Minot MC, Hilton-Jones D, Maddison P, Chinnery P, Reimann J, Kornblum C, Kraya T, Zierz S, Sue C, Goebel H, Azfer A, Ralston SH, Hackman P, Bucelli RC, Taylor JP, Weihl CC, Udd B., Free PMC Article | 07/20/2019 |
| TIA1 variants are not associated with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) in European patient cohort. | No supportive evidence for TIA1 gene mutations in a European cohort of ALS-FTD spectrum patients.
Baradaran-Heravi Y, Dillen L, Nguyen HP, Van Mossevelde S, Baets J, De Jonghe P, Engelborghs S, De Deyn PP, Vandenbulcke M, Vandenberghe R, Van Damme P, Cras P, Salmon E, Synofzik M, Heutink P, Wilke C, Simon-Sanchez J, Rojas-Garcia R, Turon-Sans J, Lleó A, Illán-Gala I, Clarimón J, Borroni B, Padovani A, Pastor P, Diez-Fairen M, Aguilar M, Gelpi E, Sanchez-Valle R, Borrego-Ecija S, Matej R, Parobkova E, Nacmias B, Sorbi S, Bagnoli S, de Mendonça A, Ferreira C, Fraidakis MJ, Diehl-Schmid J, Alexopoulos P, Almeida MR, Santana I, Van Broeckhoven C, van der Zee J, BELNEU Consortium, EU EOD Consortium. | 07/6/2019 |
| These findings suggest that Zn(2+) is a physiological ligand of TIA-1, acting as a stress-inducible second messenger to promote multimerization of TIA-1 and subsequent localization into stress granules. | TIA-1 Self-Multimerization, Phase Separation, and Recruitment into Stress Granules Are Dynamically Regulated by Zn(2).
Rayman JB, Karl KA, Kandel ER. | 03/30/2019 |
| The repression of TIA-1 by miR-487a promoted cell proliferation and suppressed cell apoptosis in vitro, and the knockdown of miR-487a had the opposite effects. | miR-487a promotes progression of gastric cancer by targeting TIA1.
Yang X, Wang M, Lin B, Yao D, Li J, Tang X, Li S, Liu Y, Xie R, Yu S. | 12/1/2018 |
| TIA1 mutation is an uncommon genetic cause for ALS in the Chinese population. | Mutation screening of the TIA1 gene in Chinese patients with amyotrophic lateral sclerosis/frontotemporal dementia.
Gu X, Chen Y, Wei Q, Cao B, Ou R, Yuan X, Hou Y, Zhang L, Liu H, Chen X, Shang HF. | 10/20/2018 |
| TIA1 LCD mutations are not common in Chinese ALS/ALS-FTD | Genetic analysis of TIA1 gene in Chinese patients with amyotrophic lateral sclerosis.
Zhang K, Liu Q, Shen D, Tai H, Fu H, Liu S, Wang Z, Shi J, Ding Q, Li X, Liu M, Cui L, Zhang X. | 10/6/2018 |
| TIA1 is a novel causative gene of amyotrophic lateral sclerosis. | Mutation analysis of the TIA1 gene in Chinese patients with amyotrophic lateral sclerosis and frontotemporal dementia.
Yuan Z, Jiao B, Hou L, Xiao T, Liu X, Wang J, Xu J, Zhou L, Yan X, Tang B, Shen L. | 09/29/2018 |
| The purpose of this report is to provide a detailed description of the clinical and neuropathological features associated with the recently identified TIA1 mutations that cause ALS +/- FTD. | Clinical and neuropathological features of ALS/FTD with TIA1 mutations.
Hirsch-Reinshagen V, Pottier C, Nicholson AM, Baker M, Hsiung GR, Krieger C, Sengdy P, Boylan KB, Dickson DW, Mesulam M, Weintraub S, Bigio E, Zinman L, Keith J, Rogaeva E, Zivkovic SA, Lacomis D, Taylor JP, Rademakers R, Mackenzie IRA., Free PMC Article | 08/18/2018 |
| TIA-1 knockdown by siRNA mimicked the effect of SAHA on COX-2 expression. These findings suggest SAHA can prevent TGF-beta1-induced COX-2 repression in lung fibroblasts post-transcriptionally through a novel TIA-1-dependent mechanism and provide new insights into the mechanisms underlying its potential antifibrotic activity | Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation.
Pasini A, Brand OJ, Jenkins G, Knox AJ, Pang L., Free PMC Article | 07/14/2018 |
| expressions of TIA-1 and MFF were augmented in the cancerous liver tissues compared to the corresponding non-tumor tissues at mRNA and protein level, while the levels of miR-200a-3p and miR-27a/b were relatively lower in the cancerous liver tissues | Potential use of TIA-1, MFF, microRNA-200a-3p, and microRNA-27 as a novel marker for hepatocellular carcinoma.
Tak H, Kang H, Ji E, Hong Y, Kim W, Lee EK. | 04/14/2018 |