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    TGFBR2 transforming growth factor beta receptor 2 [ Homo sapiens (human) ]

    Gene ID: 7048, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CD9 promotes TbetaR2-TbetaR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.

    CD9 promotes TβR2-TβR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.
    Huang W, Zhang Z, Li X, Zheng Q, Wu C, Liu L, Chen Y, Zhang J, Jiang X., Free PMC Article

    10/5/2024
    Polymorphism of Transforming Growth Factor TGFB and Its Receptors TGFBRI, TGFBRII, TGFBRIIII Genes in Western Siberia Patients with Open-Angle Glaucoma.

    Polymorphism of Transforming Growth Factor TGFB and Its Receptors TGFBRI, TGFBRII, TGFBRIIII Genes in Western Siberia Patients with Open-Angle Glaucoma.
    Shevchenko AV, Prokofiev VF, Konenkov VI, Chernykh VV, Trunov AN.

    06/17/2024
    ITGB5 facilitates gastric cancer metastasis by promoting TGFBR2 endosomal recycling.

    ITGB5 facilitates gastric cancer metastasis by promoting TGFBR2 endosomal recycling.
    Lei T, Lin Y, Lai X, Zhang Y, Ma Y, Wang X, Liu W, Tang Q, Yang T, Feng W, Song W.

    06/8/2024
    Ubiquitin-specific peptidase 11 promotes development of keloid derived fibroblasts by de-ubiquitinating TGF-beta receptorII.

    Ubiquitin-specific peptidase 11 promotes development of keloid derived fibroblasts by de-ubiquitinating TGF-β receptorII.
    Li T, Huang J, Zeng A, Yu N, Long X.

    04/15/2024
    Molecular insights into gastric cancer: The impact of TGFBR2 and hsa-mir-107 revealed by microarray sequencing and bioinformatics.

    Molecular insights into gastric cancer: The impact of TGFBR2 and hsa-mir-107 revealed by microarray sequencing and bioinformatics.
    Jin Z, Huang Z, Wu C, Zhang F, Gao Y, Guo S, Tao X, Lu S, Zhang J, Huang J, Zhai Y, Shi R, Ye P, Wu J.

    03/28/2024
    MiR-27a-3p exacerbates cell migration and invasion in right-sided/left-sided colorectal cancer by targeting TGFBR2/TCF7L2.

    MiR-27a-3p exacerbates cell migration and invasion in right-sided/left-sided colorectal cancer by targeting TGFBR2/TCF7L2.
    Bi L, Zhou Y, Zhang Y, Zhang X.

    03/21/2024
    Declined circular RNA mitofusin 2 constrains the deterioration of Wilms tumor via modulating microRNA-372-3p/transforming growth factor-beta receptor type 2 axis.

    Declined circular RNA mitofusin 2 constrains the deterioration of Wilms tumor via modulating microRNA-372-3p/transforming growth factor-β receptor type 2 axis.
    Xiao M, Pu X, Tong W, Xiao X.

    03/14/2024
    Circ_CHMP5 aggravates oxidized low-density lipoprotein-induced damage to human umbilical vein endothelial cells through miR-516b-5p/TGFbetaR2 axis.

    Circ_CHMP5 aggravates oxidized low-density lipoprotein-induced damage to human umbilical vein endothelial cells through miR-516b-5p/TGFβR2 axis.
    Wang Y, Liu P, Chen X, Yang W.

    01/12/2024
    TGF-betaRII/EP300/SMAD4 cascade signaling pathway promotes invasion and glycolysis in oral squamous cell carcinoma.

    TGF-βRII/EP300/SMAD4 cascade signaling pathway promotes invasion and glycolysis in oral squamous cell carcinoma.
    Zhang D, Peng Y, Lin G, Xiao Q, Liu H, Nan X, Han J, Zhao R, Wang Y, Liu J, Liu Y.

    07/19/2023
    Transforming growth factor beta isoforms and TGF-betaR1 and TGF-betaR2 expression in systemic sclerosis patients.

    Transforming growth factor beta isoforms and TGF-βR1 and TGF-βR2 expression in systemic sclerosis patients.
    Lomelí-Nieto JA, Muñoz-Valle JF, Baños-Hernández CJ, Navarro-Zarza JE, Godínez-Rubí JM, García-Arellano S, Ramírez-Dueñas MG, Parra-Rojas I, Villanueva-Pérez A, Hernández-Bello J.

    05/30/2023
    Proinflammatory plasticity towards Th17 paradigm of regulatory T cells consistent with elevated prevalence of TGFBR2 variants in elderly patients with primary immune thrombocytopenia.

    Proinflammatory plasticity towards Th17 paradigm of regulatory T cells consistent with elevated prevalence of TGFBR2 variants in elderly patients with primary immune thrombocytopenia.
    Cao J, Zhan Y, Ji L, Chen P, Cheng L, Li F, Zhuang X, Min Z, Sun L, Hua F, Chen H, Wu B, Cheng Y., Free PMC Article

    04/12/2023
    Suppression of CD56[bright] NK cells in breast cancer patients is associated with the PD-1 and TGF-betaRII expression.

    Suppression of CD56(bright) NK cells in breast cancer patients is associated with the PD-1 and TGF-βRII expression.
    Arianfar E, Khandoozi SR, Mohammadi S, Memarian A.

    02/23/2023
    Loss of Function TGFBR2 Variant as a Contributing Factor in Generalized Pustular Psoriasis and Adult-Onset Immunodeficiency.

    Loss of Function TGFBR2 Variant as a Contributing Factor in Generalized Pustular Psoriasis and Adult-Onset Immunodeficiency.
    Kantaputra P, Daroontum T, Chuamanochan M, Chaowattanapanit S, Intachai W, Olsen B, Sastraruji T, Tongsima S, Ngamphiw C, Kampuansai J, Cox TC, Kiratikanon S, Kantaputra P, Daroontum T, Chuamanochan M, Chaowattanapanit S, Intachai W, Olsen B, Sastraruji T, Tongsima S, Ngamphiw C, Kampuansai J, Cox TC, Kiratikanon S., Free PMC Articles: PMC9859322, PMC9859322

    02/11/2023
    Loss of Function TGFBR2 Variant as a Contributing Factor in Generalized Pustular Psoriasis and Adult-Onset Immunodeficiency.

    Loss of Function TGFBR2 Variant as a Contributing Factor in Generalized Pustular Psoriasis and Adult-Onset Immunodeficiency.
    Kantaputra P, Daroontum T, Chuamanochan M, Chaowattanapanit S, Intachai W, Olsen B, Sastraruji T, Tongsima S, Ngamphiw C, Kampuansai J, Cox TC, Kiratikanon S, Kantaputra P, Daroontum T, Chuamanochan M, Chaowattanapanit S, Intachai W, Olsen B, Sastraruji T, Tongsima S, Ngamphiw C, Kampuansai J, Cox TC, Kiratikanon S., Free PMC Articles: PMC9859322, PMC9859322

    02/10/2023
    Characterization of TGF-beta signaling in a human organotypic skin model reveals that loss of TGF-betaRII induces invasive tissue growth.

    Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth.
    Ye Z, Kilic G, Dabelsteen S, Marinova IN, Thøfner JFB, Song M, Rudjord-Levann AM, Bagdonaite I, Vakhrushev SY, Brakebusch CH, Olsen JV, Wandall HH.

    12/3/2022
    Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.

    Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
    Li B, Chen J, Wu Y, Luo H, Ke Y., Free PMC Article

    08/27/2022
    USP8 promotes cancer progression and extracellular vesicle-mediated CD8+ T cell exhaustion by deubiquitinating the TGF-beta receptor TbetaRII.

    USP8 promotes cancer progression and extracellular vesicle-mediated CD8+ T cell exhaustion by deubiquitinating the TGF-β receptor TβRII.
    Xie F, Zhou X, Li H, Su P, Liu S, Li R, Zou J, Wei X, Pan C, Zhang Z, Zheng M, Liu Z, Meng X, Ovaa H, Ten Dijke P, Zhou F, Zhang L., Free PMC Article

    08/27/2022
    Breast cancer cell-derived extracellular vesicles promote CD8(+) T cell exhaustion via TGF-beta type II receptor signaling.

    Breast cancer cell-derived extracellular vesicles promote CD8(+) T cell exhaustion via TGF-β type II receptor signaling.
    Xie F, Zhou X, Su P, Li H, Tu Y, Du J, Pan C, Wei X, Zheng M, Jin K, Miao L, Wang C, Meng X, van Dam H, Ten Dijke P, Zhang L, Zhou F., Free PMC Article

    08/6/2022
    Transforming Growth Factor Beta Receptor 2 (TGFBR2) Promoter Region Polymorphisms May Be Involved in Mandibular Retrognathism.

    Transforming Growth Factor Beta Receptor 2 (TGFBR2) Promoter Region Polymorphisms May Be Involved in Mandibular Retrognathism.
    Kirschneck M, Zbidat N, Paddenberg E, Reis CLB, Madalena IR, de Menezes-Oliveira MAH, Lepri CP, Proff P, Kirschneck C, Küchler EC., Free PMC Article

    07/2/2022
    GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma.

    GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma.
    Fang Z, Zhang N, Yuan X, Xing X, Li X, Qin X, Liu Z, Neo S, Liu C, Kong F, Björkholm M, Fan Y, Xu D., Free PMC Article

    06/11/2022
    The novel mechanism of Med12-mediated drug resistance in a TGFBR2-independent manner.

    The novel mechanism of Med12-mediated drug resistance in a TGFBR2-independent manner.
    Han Y, Dong Q, Liu T, Chen X, Yu C, Zhang Y.

    05/28/2022
    Upregulation of TGF-beta type II receptor in high glucose-induced vascular smooth muscle cells.

    Upregulation of TGF-β type II receptor in high glucose-induced vascular smooth muscle cells.
    Ghasempour G, Mohammadi A, Zamani-Garmsiri F, Soleimani AA, Najafi M.

    04/9/2022
    Downregulation of acylglycerol kinase suppresses high-glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells through regulating the LPAR1/TGF-beta/Notch signaling pathway.

    Downregulation of acylglycerol kinase suppresses high-glucose-induced endothelial-mesenchymal transition in human retinal microvascular endothelial cells through regulating the LPAR1/TGF-β/Notch signaling pathway.
    Wang H, Feng Z, Han X, Xing Y, Zhang X.

    02/26/2022
    Optimization strategies for expression of a novel bifunctional anti-PD-L1/TGFBR2-ECD fusion protein.

    Optimization strategies for expression of a novel bifunctional anti-PD-L1/TGFBR2-ECD fusion protein.
    Gao ZZ, Li C, Chen G, Yuan JJ, Zhou YQ, Jiao JY, Nie L, Qi J, Yang Y, Chen SQ, Wang HB.

    02/12/2022
    Familial exudative vitreoretinopathy with TGFBR2 mutation without signs of Loeys-Dietz syndrome.

    Familial exudative vitreoretinopathy with TGFBR2 mutation without signs of Loeys-Dietz syndrome.
    Asano T, Oku K, Kondo H.

    01/29/2022
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