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    TFRC transferrin receptor [ Homo sapiens (human) ]

    Gene ID: 7037, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The Plasmodium vivax MSP1P-19 is involved in binding of reticulocytes through interactions with the membrane proteins band3 and CD71.

    The Plasmodium vivax MSP1P-19 is involved in binding of reticulocytes through interactions with the membrane proteins band3 and CD71.
    Zuo S, Lu J, Sun Y, Song J, Han S, Feng X, Han ET, Cheng Y., Free PMC Article

    06/6/2024
    Transferrin receptor 1 promotes hepatocellular carcinoma progression and metastasis by activating the mTOR signaling pathway.

    Transferrin receptor 1 promotes hepatocellular carcinoma progression and metastasis by activating the mTOR signaling pathway.
    Wang F, Xu WQ, Zhang WQ, Xu RC, Sun JL, Zhang GC, Liu ZY, Qi ZR, Dong L, Weng SQ, Shen XZ, Liu TT, Fang Y, Zhu JM.

    04/17/2024
    E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma.

    E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma.
    Shao M, Qi K, Wang L, Yu X, Zhang Q, Yu L, Wang L, Yang C, Fan L.

    04/12/2024
    TFR1-Mediated Iron Metabolism Orchestrates Tumor Ferroptosis and Immunity in Non-Small Cell Lung Cancer.

    TFR1-Mediated Iron Metabolism Orchestrates Tumor Ferroptosis and Immunity in Non-Small Cell Lung Cancer.
    Wang Z, Yao X, Wang K, Wang B.

    03/21/2024
    Correlation between ferroptosis and adriamycin resistance in breast cancer regulated by transferrin receptor and its molecular mechanism.

    Correlation between ferroptosis and adriamycin resistance in breast cancer regulated by transferrin receptor and its molecular mechanism.
    Yu X, Cheng L, Liu S, Wang M, Zhang H, Wang X, Zhang H, Yang Z, Wu S.

    03/14/2024
    Human transferrin receptor can mediate SARS-CoV-2 infection.

    Human transferrin receptor can mediate SARS-CoV-2 infection.
    Liao Z, Wang C, Tang X, Yang M, Duan Z, Liu L, Lu S, Ma L, Cheng R, Wang G, Liu H, Yang S, Xu J, Tadese DA, Mwangi J, Kamau PM, Zhang Z, Yang L, Liao G, Zhao X, Peng X, Lai R., Free PMC Article

    02/29/2024
    METTL3 regulates TFRC ubiquitination and ferroptosis through stabilizing NEDD4L mRNA to impact stroke.

    METTL3 regulates TFRC ubiquitination and ferroptosis through stabilizing NEDD4L mRNA to impact stroke.
    Su W, Yu X, Wang S, Wang X, Dai Z, Li Y., Free PMC Article

    02/12/2024
    Transferrin receptor levels and its rare variant are associated with human obesity.

    Transferrin receptor levels and its rare variant are associated with human obesity.
    Qiu J, Zhang Z, Hu Y, Guo Y, Liu C, Chen Y, Wang D, Su J, Wang S, Ni M, Xu S, Yu J, Hu T, Song G, Ma X, Gu X, Wang J, Xu L., Free PMC Article

    02/7/2024
    Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition.

    Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition.
    Yu L, Wang YF, Xiao J, Shen QQ, Chi SS, Gao YL, Lin DZ, Ding J, Fang YF, Chen Y.,

    10/12/2023
    The hepatic niche leads to aggressive natural killer cell leukemia proliferation through the transferrin-transferrin receptor 1 axis.

    The hepatic niche leads to aggressive natural killer cell leukemia proliferation through the transferrin-transferrin receptor 1 axis.
    Kameda K, Yanagiya R, Miyatake Y, Carreras J, Higuchi H, Murayama H, Ishida T, Ito A, Iida S, Fukuhara N, Harigae H, Fujioka Y, Takahashi N, Wada H, Ishida F, Nakazawa H, Ishihara R, Murakami Y, Tagawa H, Matsuura T, Nakagawa S, Iwabuchi S, Hashimoto S, Imadome KI, Nakamura N, Ishizawa K, Kanda Y, Ando K, Kotani A.

    07/31/2023
    H3K9 trimethylation dictates neuronal ferroptosis through repressing Tfr1.

    H3K9 trimethylation dictates neuronal ferroptosis through repressing Tfr1.
    Lan T, Hu L, Sun T, Wang X, Xiao Z, Shen D, Wu W, Luo Z, Wei C, Wang X, Liu M, Guo Y, Wang L, Wang Y, Lu Y, Yu Y, Yang F, Zhang C, Li Q., Free PMC Article

    07/21/2023
    TfR1 gene expression as a potential biomarker for iron deficiency in heart failure.

    TfR1 gene expression as a potential biomarker for iron deficiency in heart failure.
    Mutoli M, Martelli F, Spinetti G.

    06/22/2023
    Cultured CD71[+] erythroid cells modulate the host immune response.

    Cultured CD71(+) erythroid cells modulate the host immune response.
    Alshalani A, Beuger BM, van Bruggen R, Acker JP, Juffermans NP.

    06/16/2023
    Influenza A virus exploits transferrin receptor recycling to enter host cells.

    Influenza A virus exploits transferrin receptor recycling to enter host cells.
    Mazel-Sanchez B, Niu C, Williams N, Bachmann M, Choltus H, Silva F, Serre-Beinier V, Karenovics W, Iwaszkiewicz J, Zoete V, Kaiser L, Hartley O, Wehrle-Haller B, Schmolke M., Free PMC Article

    05/19/2023
    NUF2 Drives Cholangiocarcinoma Progression and Migration via Inhibiting Autophagic Degradation of TFR1.

    NUF2 Drives Cholangiocarcinoma Progression and Migration via Inhibiting Autophagic Degradation of TFR1.
    Shan J, Jiang W, Chang J, Zhou T, Chen Y, Zhang Y, Wang J, Wang Y, Wang Y, Xu X, Liu S, Shi X, Fan S, Chen R, Li C, Li X., Free PMC Article

    04/19/2023
    Elevated expression of receptors for EGF, PDGF, transferrin and folate within murine and human lupus nephritis kidneys.

    Elevated expression of receptors for EGF, PDGF, transferrin and folate within murine and human lupus nephritis kidneys.
    Xie S, Louis Sam Titus ASC, Mohan C.

    03/7/2023
    Transferrin Receptor Protein 1 Is an Entry Factor for Rabies Virus.

    Transferrin Receptor Protein 1 Is an Entry Factor for Rabies Virus.
    Wang X, Wen Z, Cao H, Luo J, Shuai L, Wang C, Ge J, Wang X, Bu Z, Wang J., Free PMC Article

    03/3/2023
    Regulation of transferrin receptor trafficking by optineurin and its disease-associated mutants.

    Regulation of transferrin receptor trafficking by optineurin and its disease-associated mutants.
    Moharir SC, Sirohi K, Swarup G.

    02/10/2023
    TFR1 expression in induced sputum is associated with asthma severity.

    TFR1 expression in induced sputum is associated with asthma severity.
    Wang Y, Gu LF, Zhao X, Hu C, Chen Q., Free PMC Article

    01/21/2023
    Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus.

    Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus.
    Voss K, Sewell AE, Krystofiak ES, Gibson-Corley KN, Young AC, Basham JH, Sugiura A, Arner EN, Beavers WN, Kunkle DE, Dickson ME, Needle GA, Skaar EP, Rathmell WK, Ormseth MJ, Major AS, Rathmell JC., Free PMC Article

    01/21/2023
    Relationship Between Soluble Transferrin Receptor and Clinical Outcomes in Patients With Heart Failure According to Ejection Fraction Phenotype: The New Zealand PEOPLE Study.

    Relationship Between Soluble Transferrin Receptor and Clinical Outcomes in Patients With Heart Failure According to Ejection Fraction Phenotype: The New Zealand PEOPLE Study.
    Fitzsimons S, Poppe KK, Choi Y, Devlin G, Lund M, Lam CSP, Troughton R, Richards AM, Doughty RN.

    08/20/2022
    TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.

    TFRC upregulation promotes ferroptosis in CVB3 infection via nucleus recruitment of Sp1.
    Yi L, Hu Y, Wu Z, Li Y, Kong M, Kang Z, Zuoyuan B, Yang Z., Free PMC Article

    07/23/2022
    Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells.

    Iron metabolism protein transferrin receptor 1 involves in cervical cancer progression by affecting gene expression and alternative splicing in HeLa cells.
    Huang N, Wei Y, Cheng Y, Wang X, Wang Q, Chen D, Li W.

    05/28/2022
    Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections.

    Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections.
    Hickerson BT, Daniels-Wells TR, Payes C, Clark LE, Candelaria PV, Bailey KW, Sefing EJ, Zink S, Ziegenbein J, Abraham J, Helguera G, Penichet ML, Gowen BB., Free PMC Article

    02/26/2022
    Integrated analysis identifies TfR1 as a prognostic biomarker which correlates with immune infiltration in breast cancer.

    Integrated analysis identifies TfR1 as a prognostic biomarker which correlates with immune infiltration in breast cancer.
    Chen F, Fan Y, Hou J, Liu B, Zhang B, Shang Y, Chang Y, Cao P, Tan K., Free PMC Article

    01/15/2022
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