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    ZEB1 zinc finger E-box binding homeobox 1 [ Homo sapiens (human) ]

    Gene ID: 6935, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CCT2 Regulates ZEB1-Induced EMT Gene Transcription to Promote the Metastasis and Tumorigenesis of Papillary Thyroid Carcinoma.

    CCT2 Regulates ZEB1-Induced EMT Gene Transcription to Promote the Metastasis and Tumorigenesis of Papillary Thyroid Carcinoma.
    Liu W, Lin R, Zhu C, Chen Y, Gao Q, Zhong J.

    10/1/2024
    ZEB1 interferes with human periodontal ligament stem cell proliferation and differentiation.

    ZEB1 interferes with human periodontal ligament stem cell proliferation and differentiation.
    Qian L, Ni J, Zhang Z.

    09/23/2024
    Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition.

    Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition.
    Schwab A, Rao Z, Zhang J, Gollowitzer A, Siebenkäs K, Bindel N, D'Avanzo E, van Roey R, Hajjaj Y, Özel E, Armstark I, Bereuter L, Su F, Grander J, Bonyadi Rad E, Groenewoud A, Engel FB, Bell GW, Henry WS, Angeli JPF, Stemmler MP, Brabletz S, Koeberle A, Brabletz T., Free PMC Article

    09/13/2024
    Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.

    Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
    Li T, Wei L, Zhang X, Fu B, Zhou Y, Yang M, Cao M, Chen Y, Tan Y, Shi Y, Wu L, Xuan C, Du Q, Hu R.

    09/3/2024
    Correlation of FBXO45 Expression Levels with Cancer Severity by ZEB1 Ubiquitin in Non-Small-Cell Lung Cancer.

    Correlation of FBXO45 Expression Levels with Cancer Severity by ZEB1 Ubiquitin in Non-Small-Cell Lung Cancer.
    Zhang F, Wang Y, He Y, Dong B.

    08/5/2024
    Endothelial cell specific molecule 1 promotes epithelial-mesenchymal transition of cervical cancer via the E-box binding homeobox 1.

    Endothelial cell specific molecule 1 promotes epithelial-mesenchymal transition of cervical cancer via the E-box binding homeobox 1.
    Qi J, Li J, Zhu X, Zhao S., Free PMC Article

    07/24/2024
    CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis.

    CircAGFG1 Promotes Ovarian Cancer Progression Through the miR-409-3 p/ZEB1 Axis.
    Luo J, Zhong H, Guo M, Xiao P, Cao R, Zhao M, Jing Y., Free PMC Article

    07/15/2024
    ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions.

    ZEB1 controls a lineage-specific transcriptional program essential for melanoma cell state transitions.
    Durand S, Tang Y, Pommier RM, Benboubker V, Grimont M, Boivin F, Barbollat-Boutrand L, Cumunel E, Dupeuble F, Eberhardt A, Plaschka M, Dalle S, Caramel J., Free PMC Article

    07/11/2024
    LINC01806 Promotes Breast Cancer Growth and Metastasis via Sponging miR-1286 to Disinhibit ZEB1 Expression.

    LINC01806 Promotes Breast Cancer Growth and Metastasis via Sponging miR-1286 to Disinhibit ZEB1 Expression.
    Liu Y, Xiang Q, Yang T, Wang J, Li H.

    07/5/2024
    GINS1 promotes ZEB1-mediated epithelial-mesenchymal transition and tumor metastasis via beta-catenin signaling in hepatocellular carcinoma.

    GINS1 promotes ZEB1-mediated epithelial-mesenchymal transition and tumor metastasis via β-catenin signaling in hepatocellular carcinoma.
    Liang J, Yao N, Deng B, Li J, Jiang Y, Liu T, Hu Y, Cao M, Hong J.

    05/31/2024
    Extracellular matrix marker LAMC2 targets ZEB1 to promote TNBC malignancy via up-regulating CD44/STAT3 signaling pathway.

    Extracellular matrix marker LAMC2 targets ZEB1 to promote TNBC malignancy via up-regulating CD44/STAT3 signaling pathway.
    Wang D, Keyoumu K, Yu R, Wen D, Jiang H, Liu X, Di X, Zhang S., Free PMC Article

    05/21/2024
    miR-200b-3p relieved inflammation in patients with heart failure by regulating ZEB1 expression.

    miR-200b-3p relieved inflammation in patients with heart failure by regulating ZEB1 expression.
    Wei B, Li Z, Wang L, Zhang H, Gou W., Free PMC Article

    05/20/2024
    The deubiquitinase BRCC3 increases the stability of ZEB1 and promotes the proliferation and metastasis of triple-negative breast cancer cells.

    The deubiquitinase BRCC3 increases the stability of ZEB1 and promotes the proliferation and metastasis of triple-negative breast cancer cells.
    Huang Q, Zheng S, Gu H, Yang Z, Lu Y, Yu X, Guo G., Free PMC Article

    05/2/2024
    Long Non-coding RNA X-Inactive Specific Transcript Promotes Esophageal Squamous Cell Carcinoma Progression via the MicroRNA 34a/Zinc Finger E-box-Binding Homeobox 1 Pathway.

    Long Non-coding RNA X-Inactive Specific Transcript Promotes Esophageal Squamous Cell Carcinoma Progression via the MicroRNA 34a/Zinc Finger E-box-Binding Homeobox 1 Pathway.
    Guo B, He M, Ma M, Tian Z, Jin J, Tian G., Free PMC Article

    04/30/2024
    ZEB1 Is Regulated by K811 Acetylation to Promote Stability, NuRD Complex Interactions, EMT, and NSCLC Metastasis.

    ZEB1 Is Regulated by K811 Acetylation to Promote Stability, NuRD Complex Interactions, EMT, and NSCLC Metastasis.
    Perez-Oquendo M, Manshouri R, Tian Y, Fradette JJ, Rodriguez BL, Kundu ST, Gibbons DL., Free PMC Article

    03/29/2024
    ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.

    ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion.
    Bassani B, Simonetti G, Cancila V, Fiorino A, Ciciarello M, Piva A, Khorasani AM, Chiodoni C, Lecis D, Gulino A, Fonzi E, Botti L, Portararo P, Costanza M, Brambilla M, Colombo G, Schwaller J, Tzankov A, Ponzoni M, Ciceri F, Bolli N, Curti A, Tripodo C, Colombo MP, Sangaletti S.

    03/5/2024
    Loss-of-function variants in ZEB1 cause dominant anomalies of the corpus callosum with favourable cognitive prognosis.

    Loss-of-function variants in ZEB1 cause dominant anomalies of the corpus callosum with favourable cognitive prognosis.
    Heide S, Argilli E, Valence S, Boutaud L, Roux N, Mignot C, Nava C, Keren B, Giraudat K, Faudet A, Gerasimenko A, Garel C, Blondiaux E, Rastetter A, Grevent D, Le C, Mackenzie L, Richards L, Attié-Bitach T, Depienne C, Sherr E, Héron D.

    02/23/2024
    miR-186 regulates epithelial-mesenchymal transformation to promote nasopharyngeal carcinoma metastasis by targeting ZEB1.

    miR-186 regulates epithelial-mesenchymal transformation to promote nasopharyngeal carcinoma metastasis by targeting ZEB1.
    Tang L, Xiang Y, Zhou J, Li T, Jia T, Du G., Free PMC Article

    01/30/2024
    Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPalpha axis.

    Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis.
    Chen XJ, Guo CH, Wang ZC, Yang Y, Pan YH, Liang JY, Sun MG, Fan LS, Liang L, Wang W., Free PMC Article

    01/26/2024
    miR-200a-3p regulates epithelial-mesenchymal transition and inflammation in chronic rhinosinusitis with nasal polyps by targeting ZEB1 via ERK/p38 pathway.

    miR-200a-3p regulates epithelial-mesenchymal transition and inflammation in chronic rhinosinusitis with nasal polyps by targeting ZEB1 via ERK/p38 pathway.
    Wu Y, Sun K, Tu Y, Li P, Hao D, Yu P, Chen A, Wan Y, Shi L.

    01/26/2024
    ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer.

    ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer.
    Fernandez-De-Los-Reyes I, Gomez-Dorronsoro M, Monreal-Santesteban I, Fernandez-Fernandez A, Fraga M, Azcue P, Alonso L, Fernandez-Marlasca B, Suarez J, Cordoba-Iturriagagoitia A, Guerrero-Setas D., Free PMC Article

    12/20/2023
    lncRNA799/TBL1XR1/ZEB1 Axis Forms a Feedback Loop to Promote the Epithelial-Mesenchymal Transition of Cervical Cancer Cells.

    lncRNA799/TBL1XR1/ZEB1 Axis Forms a Feedback Loop to Promote the Epithelial-Mesenchymal Transition of Cervical Cancer Cells.
    Liao L, Huang P, Zhao J, Wang Z, Chen H, Zhang C, Huang L.

    12/20/2023
    The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2.

    The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2.
    Ninfali C, Siles L, Esteve-Codina A, Postigo A.

    12/5/2023
    Loss of Key EMT-Regulating miRNAs Highlight the Role of ZEB1 in EGFR Tyrosine Kinase Inhibitor-Resistant NSCLC.

    Loss of Key EMT-Regulating miRNAs Highlight the Role of ZEB1 in EGFR Tyrosine Kinase Inhibitor-Resistant NSCLC.
    Gohlke L, Alahdab A, Oberhofer A, Worf K, Holdenrieder S, Michaelis M, Cinatl J Jr, Ritter CA., Free PMC Article

    11/15/2023
    PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.

    PRMT1 accelerates cell proliferation, migration, and tumor growth by upregulating ZEB1/H4R3me2as in thyroid carcinoma.
    Feng G, Chen C, Luo Y., Free PMC Article

    11/13/2023
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