Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy. | Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy. Wu W, Jia H, Chen S, Ma X, Zhou S, Qiu L, Wu X, Li P, Chu H, Zhang G., Free PMC Article | 06/7/2024 |
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy. | Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy. Ji H, Zhao Y, Ma X, Wu L, Guo F, Huang F, Song Y, Wang J, Qin G. | 05/31/2024 |
Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons. | Insulin signalling regulates Pink1 mRNA localization via modulation of AMPK activity to support PINK1 function in neurons. Hees JT, Wanderoy S, Lindner J, Helms M, Murali Mahadevan H, Harbauer AB., Free PMC Article | 03/31/2024 |
Pink1 deficiency enhances neurological deficits and inflammatory responses after intracerebral hemorrhage in mice. | Pink1 deficiency enhances neurological deficits and inflammatory responses after intracerebral hemorrhage in mice. Li J, Li J, Guo E, Wang Y, Yang M, Huo H, Shi Y, Zhao L., Free PMC Article | 03/26/2024 |
PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway. | PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway. Zheng F, Zhong J, Chen K, Shi Y, Wang F, Wang S, Tang S, Yuan X, Shen Z, Tang S, Xia D, Wu Y, Lu W., Free PMC Article | 03/15/2024 |
METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy. | METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy. Wang F, Bai J, Zhang X, Wang D, Zhang X, Xue J, Chen H, Wang S, Chi B, Li J, Ma X., Free PMC Article | 03/13/2024 |
PINK1 dominated mitochondria associated genes signature predicts abdominal aortic aneurysm with metabolic syndrome. | PINK1 dominated mitochondria associated genes signature predicts abdominal aortic aneurysm with metabolic syndrome. Wang K, Zhou Z, Huang L, Kan Q, Wang Z, Wu W, Yao C. | 02/16/2024 |
PINK1 restrains periodontitis-induced bone loss by preventing osteoclast mitophagy impairment. | PINK1 restrains periodontitis-induced bone loss by preventing osteoclast mitophagy impairment. Jang JS, Hong SJ, Mo S, Kim MK, Kim YG, Lee Y, Kim HH., Free PMC Article | 02/1/2024 |
Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia-Reperfusion Injury by Promoting Pink1-Parkin-Mediated Mitophagy. | Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia-Reperfusion Injury by Promoting Pink1-Parkin-Mediated Mitophagy. Zhang Y, Wang Z, Jia C, Yu W, Li X, Xia N, Nie H, Wikana LP, Chen M, Ni Y, Han S, Pu L., Free PMC Article | 12/27/2023 |
Critical roles of parkin and PINK1 in coxsackievirus B3-induced viral myocarditis. | Critical roles of parkin and PINK1 in coxsackievirus B3-induced viral myocarditis. Jin U, Park SJ, Lee BG, Kim JB, Kim SJ, Joe EH, Woo HG, Park SM. | 12/20/2023 |
Role of Pink1-mediated mitophagy in adenomyosis. | Role of Pink1-mediated mitophagy in adenomyosis. Chen M, Wang W, Fu X, Yi Y, Wang K, Wang M., Free PMC Article | 12/6/2023 |
PTEN-induced kinase 1 exerts protective effects in diabetic kidney disease by attenuating mitochondrial dysfunction and necroptosis. | PTEN-induced kinase 1 exerts protective effects in diabetic kidney disease by attenuating mitochondrial dysfunction and necroptosis. Sung MJ, An HJ, Ha MH, Park SH, Jeong HY, Baek J, Lee SH, Lee YH, Lee SY., Free PMC Article | 11/14/2023 |
C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy. | C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy. Zhang H, Li C, Liu Q, Li J, Wu H, Xu R, Sun Y, Cheng M, Zhao X, Pan M, Wei Q, Ma B., Free PMC Article | 10/30/2023 |
PTEN-induced kinase 1 is associated with renal aging, via the cGAS-STING pathway. | PTEN-induced kinase 1 is associated with renal aging, via the cGAS-STING pathway. Ha MH, Kim MS, An HJ, Sung MJ, Lee YH, Yang DH, Jung SH, Baek J, Choi Y, Taylor DM, Zhang Y, Lee SY, Jeong HY., Free PMC Article | 09/11/2023 |
Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent. | Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent. Hou X, Chen TH, Koga S, Bredenberg JM, Faroqi AH, Delenclos M, Bu G, Wszolek ZK, Carr JA, Ross OA, McLean PJ, Murray ME, Dickson DW, Fiesel FC, Springer W., Free PMC Article | 08/31/2023 |
HYPERBILIRUBINEMIA AGGRAVATES RENAL ISCHEMIA REPERFUSION INJURY BY EXACERBATING PINK1-PARKIN-MEDIATED MITOPHAGY. | HYPERBILIRUBINEMIA AGGRAVATES RENAL ISCHEMIA REPERFUSION INJURY BY EXACERBATING PINK1-PARKIN-MEDIATED MITOPHAGY. Liao P, Wang X, Dong H, Chai D, Yue Z, Lyu L. | 08/25/2023 |
CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease. | CERS6-derived ceramides aggravate kidney fibrosis by inhibiting PINK1-mediated mitophagy in diabetic kidney disease. Wang X, Song M, Li X, Su C, Yang Y, Wang K, Liu C, Zheng Z, Jia Y, Ren S, Dong W, Chen J, Wang T, Liu L, Guan M, Zhang C, Xue Y., Free PMC Article | 08/9/2023 |
Deficiency of Pink1 promotes the differentiation of Th1 cells. | Deficiency of Pink1 promotes the differentiation of Th1 cells. Mei X, Lei Y, Ouyang L, Zhao M, Lu Q. | 07/27/2023 |
MiRNA-1976 Regulates the Apoptosis of Dopaminergic Neurons by Targeting the PINK1 Gene. | MiRNA-1976 Regulates the Apoptosis of Dopaminergic Neurons by Targeting the PINK1 Gene. Qiu F, Wu Y, Xie G, Cao H, Du M, Jiang H. | 04/6/2023 |
PINK1 deficiency with Ca[2+] changes in the hippocampus exacerbates septic encephalopathy in mice. | PINK1 deficiency with Ca(2+) changes in the hippocampus exacerbates septic encephalopathy in mice. Li C, Yu T, Li W, Gong L, Shi J, Liu H, Yu J. | 03/14/2023 |
PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control. | PINK1 protects against dendritic cell dysfunction during sepsis through the regulation of mitochondrial quality control. Wu Y, Chen L, Qiu Z, Zhang X, Zhao G, Lu Z., Free PMC Article | 02/24/2023 |
Nrf2/PINK1-mediated mitophagy induction alleviates sodium fluoride-induced hepatic injury by improving mitochondrial function, oxidative stress, and inflammation. | Nrf2/PINK1-mediated mitophagy induction alleviates sodium fluoride-induced hepatic injury by improving mitochondrial function, oxidative stress, and inflammation. Song C, Zhang A, Zhang M, Song Y, Huangfu H, Jin S, Sun Y, Zhang C, Shi D, Wang J, Peng W, Luo Q. | 02/23/2023 |
PINK1/Parkin-mediated mitophagy inhibits osteoblast apoptosis induced by advanced oxidation protein products. | PINK1/Parkin-mediated mitophagy inhibits osteoblast apoptosis induced by advanced oxidation protein products. Li W, Jiang WS, Su YR, Tu KW, Zou L, Liao CR, Wu Q, Wang ZH, Zhong ZM, Chen JT, Zhu SY., Free PMC Article | 02/13/2023 |
Protective Effect of Electroacupuncture on the Barrier Function of Intestinal Injury in Endotoxemia through HO-1/PINK1 Pathway-Mediated Mitochondrial Dynamics Regulation. | Protective Effect of Electroacupuncture on the Barrier Function of Intestinal Injury in Endotoxemia through HO-1/PINK1 Pathway-Mediated Mitochondrial Dynamics Regulation. Zhang Y, Meng Z, Wu L, Liu X, Guo C, Yu J, Ming D, Dong S, Cao Y, Jiang X., Free PMC Article | 01/21/2023 |
Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice. | Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice. Cossu D, Yokoyama K, Sato S, Noda S, Sakanishi T, Sechi LA, Hattori N., Free PMC Article | 12/10/2022 |