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    KLF5 KLF transcription factor 5 [ Homo sapiens (human) ]

    Gene ID: 688, updated on 24-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma.

    KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma.
    Yang Z, Peng Y, Wang Y, Yang P, Huang Z, Quan T, Xu X, Sun P, Sun Y, Lv J, Wei D, Zhou GQ.

    06/17/2024
    Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition.

    Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition.
    Zhang Z, Liu Y, Xu Y, Xu Z, Jia J, Jin Y, Wang W, Liu L., Free PMC Article

    05/2/2024
    KLF5 promotes the ossification process of ligamentum flavum by transcriptionally activating CX43.

    KLF5 promotes the ossification process of ligamentum flavum by transcriptionally activating CX43.
    Guo H, Yang L, Liu J, Chen L, Huang Y, Li J., Free PMC Article

    04/22/2024
    Ubiquitin specific peptidase 38 epigenetically regulates KLF transcription factor 5 to augment malignant progression of lung adenocarcinoma.

    Ubiquitin specific peptidase 38 epigenetically regulates KLF transcription factor 5 to augment malignant progression of lung adenocarcinoma.
    Zhang T, Su F, Wang B, Liu L, Lu Y, Su H, Ling R, Yue P, Dai H, Yang T, Yang J, Chen R, Wu R, Zhu K, Zhao D, Hou X.

    04/18/2024
    Depression of LncRNA DANCR alleviates tubular injury in diabetic nephropathy by regulating KLF5 through sponge miR-214-5p.

    Depression of LncRNA DANCR alleviates tubular injury in diabetic nephropathy by regulating KLF5 through sponge miR-214-5p.
    Kuang Y, Yang J, Sun M, Rui T, Yang Z, Shi M., Free PMC Article

    04/17/2024
    [Overexpression of tuftelin and KLF-5 and its clinicopathological features in hepatitis B virus-related hepatocellular carcinoma].

    [Overexpression of tuftelin and KLF-5 and its clinicopathological features in hepatitis B virus-related hepatocellular carcinoma].
    Yang JL, Fang RF, Xie Q, Tai BJ, Yao DF, Yao M.

    04/4/2024
    KLF5 inhibits the migration and invasion in cervical cancer cell lines by regulating SNAI1.

    KLF5 inhibits the migration and invasion in cervical cancer cell lines by regulating SNAI1.
    Qu X, Xu C, Yang W, Li Q, Tu S, Gao C., Free PMC Article

    04/3/2024
    Suppression of KLF5 basal expression in oral carcinoma-derived cells through three intact CREB1-binding sites in the silencer region.

    Suppression of KLF5 basal expression in oral carcinoma-derived cells through three intact CREB1-binding sites in the silencer region.
    Katsuumi R, Negishi T, Imai K, Mihara N.

    03/8/2024
    Circ_0068481 Affects the Human Pulmonary Artery Smooth Muscle Cells' Progression by miR-361-3p/KLF5 Axis.

    Circ_0068481 Affects the Human Pulmonary Artery Smooth Muscle Cells' Progression by miR-361-3p/KLF5 Axis.
    Li HR, Chen GL, Fang XL, Cai XJ, Xu RL, Li DD, Zhang ZW.

    12/22/2023
    KLF5/MDM2 Axis Modulates Oxidative Stress and Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells: The Role in Diabetic Cataract.

    KLF5/MDM2 Axis Modulates Oxidative Stress and Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells: The Role in Diabetic Cataract.
    Li X, Chen D, Ouyang B, Wang S, Li Y, Li L, Zhu S, Zheng G.

    11/22/2023
    KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian Cancer.

    KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian Cancer.
    Wu Y, Chen S, Shao Y, Su Y, Li Q, Wu J, Zhu J, Wen H, Huang Y, Zheng Z, Chen X, Ju X, Huang S, Wu X, Hu Z., Free PMC Article

    11/10/2023
    Analysis of KLF7 and KLF5 transcription factors gene variants in coronary artery disease.

    Analysis of KLF7 and KLF5 transcription factors gene variants in coronary artery disease.
    Akbari Kordkheyli V, Poursheikhani A, Sharobandi SH, Hosseini SM.

    10/6/2023
    LncRNA H19 aggravates primary graft dysfunction after lung transplantation via KLF5-mediated activation of CCL28.

    LncRNA H19 aggravates primary graft dysfunction after lung transplantation via KLF5-mediated activation of CCL28.
    Li J, Han Z, Zhu Z, Wei L.

    10/4/2023
    Suppression of Kruppel-like factor 5 basal expression by CREB1 binding to far distal element.

    Suppression of Krüppel-like factor 5 basal expression by CREB1 binding to far distal element.
    Mihara N, Imai K.

    09/12/2023
    KLF5-mediated CDCA5 expression promotes tumor development and progression of epithelial ovarian carcinoma.

    KLF5-mediated CDCA5 expression promotes tumor development and progression of epithelial ovarian carcinoma.
    Chen X, Zhou M, Ma S, Wu H, Cai H.

    06/16/2023
    KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress.

    KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress.
    Yang Y, Bhargava D, Chen X, Zhou T, Dursuk G, Jiang W, Wang J, Zong Z, Katz SI, Lomberk GA, Urrutia RA, Katz JP., Free PMC Article

    05/19/2023
    Targeting the KLF5-EphA2 axis can restrain cancer stemness and overcome chemoresistance in basal-like breast cancer.

    Targeting the KLF5-EphA2 axis can restrain cancer stemness and overcome chemoresistance in basal-like breast cancer.
    Zhao P, Sun J, Huang X, Zhang X, Liu X, Liu R, Du G, Gan W, Yang C, Tang Y, Chen C, Jiang D., Free PMC Article

    04/19/2023
    KLF5-mediated aquaporin 3 activated autophagy to facilitate cisplatin resistance of gastric cancer.

    KLF5-mediated aquaporin 3 activated autophagy to facilitate cisplatin resistance of gastric cancer.
    Dai X, Chen Y, Chen N, Dou J, Zhuang H, Wang J, Zhao X, Zhang X, Zhao H.

    03/28/2023
    Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer.

    Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer.
    Zou H, Luo J, Guo Y, Tong T, Liu Y, Chen Y, Xiao Y, Ye L, Zhu C, Deng L, Wang B, Pan Y, Li P., Free PMC Article

    02/11/2023
    Long non-coding RNA ERVK13-1 aggravates osteosarcoma through the involvement of microRNA-873-5p/KLF5 axis.

    Long non-coding RNA ERVK13-1 aggravates osteosarcoma through the involvement of microRNA-873-5p/KLF5 axis.
    Xie H, Dai L, Ye B, Chen R, Wang B, Zhang N, Miao H, Liang W.

    12/31/2022
    LINC00665 affects the malignant biological behavior of ovarian cancer via the miR-148b-3p/KLF5.

    LINC00665 affects the malignant biological behavior of ovarian cancer via the miR-148b-3p/KLF5.
    Wang S, Liu C, Li Y, Qiao J, Chen X, Bao J, Li R, Xing Y.

    10/29/2022
    [MiR-21 Regulates the Proliferation of Multiple Myeloma Cells by Inhibiting the Expression of KLF5].

    [MiR-21 Regulates the Proliferation of Multiple Myeloma Cells by Inhibiting the Expression of KLF5].
    Zhou N, Cao SX, Luo JM, Liu XJ, Yang L.

    10/15/2022
    Kruppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency.

    Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency.
    Ai Z, Xiang X, Xiang Y, Szczerbinska I, Qian Y, Xu X, Ma C, Su Y, Gao B, Shen H, Bin Ramli MN, Chen D, Liu Y, Hao JJ, Ng HH, Zhang D, Chan YS, Liu W, Liang H.

    09/3/2022
    KLF5 promotes KIF1A expression through transcriptional repression of microRNA-338 in the development of pediatric neuroblastoma.

    KLF5 promotes KIF1A expression through transcriptional repression of microRNA-338 in the development of pediatric neuroblastoma.
    Zhou Y, Tang X, Huang Z, Wen J, Xiang Q, Liu D.

    08/20/2022
    CircCDK14 ameliorates interleukin-1beta-induced chondrocyte damage by the miR-1183/KLF5 pathway in osteoarthritis.

    CircCDK14 ameliorates interleukin-1β-induced chondrocyte damage by the miR-1183/KLF5 pathway in osteoarthritis.
    Lai X, Song Y, Tian J.

    08/6/2022
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