| Mesenchymal stem cell-derived extracellular vesicles ameliorate renal interstitial fibrosis via the miR-13474/ADAM17 axis. | Mesenchymal stem cell-derived extracellular vesicles ameliorate renal interstitial fibrosis via the miR-13474/ADAM17 axis.
Shi L, Hu Y, Zeng H, Shi H, Xu W, Sun Y, Chu H, Ji C, Qian H., Free PMC Article | 09/10/2024 |
| TACE inhibition: a promising therapeutic intervention against AATF-mediated steatohepatitis to hepatocarcinogenesis. | TACE inhibition: a promising therapeutic intervention against AATF-mediated steatohepatitis to hepatocarcinogenesis.
Srinivas AN, Suresh D, Vishwanath PM, Satish S, Santhekadur PK, Koka S, Kumar DP., Free PMC Article | 08/9/2024 |
| Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17. | Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17.
Dolla G, Nicolas S, Dos Santos LR, Bourgeois A, Pardossi-Piquard R, Bihl F, Zaghrini C, Justino J, Payré C, Mansuelle P, Garbers C, Ronco P, Checler F, Lambeau G, Petit-Paitel A., Free PMC Article | 07/29/2024 |
| Downregulation of the metalloproteinases ADAM10 or ADAM17 promotes osteoclast differentiation. | Downregulation of the metalloproteinases ADAM10 or ADAM17 promotes osteoclast differentiation.
Babendreyer A, Kieselhorst J, Rinkens C, Lyashenko AM, Düsterhöft S, Jahr H, Craveiro RB, Wolf M, Ludwig A., Free PMC Article | 06/25/2024 |
| Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals. | Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals.
Lu F, Zhao H, Dai Y, Wang Y, Lee CH, Freeman M., Free PMC Article | 06/17/2024 |
| Regulation of Mertk Surface Expression via ADAM17 and gamma-Secretase Proteolytic Processing. | Regulation of Mertk Surface Expression via ADAM17 and γ-Secretase Proteolytic Processing.
Lahey KC, Varsanyi C, Wang Z, Aquib A, Gadiyar V, Rodrigues AA, Pulica R, Desind S, Davra V, Calianese DC, Liu D, Cho JH, Kotenko SV, De Lorenzo MS, Birge RB., Free PMC Article | 05/7/2024 |
| The Important Role of Phosphatidylserine, ADAM17, TNF-Alpha, and Soluble MER on Efferocytosis Activity in Central Obesity. | The Important Role of Phosphatidylserine, ADAM17, TNF-Alpha, and Soluble MER on Efferocytosis Activity in Central Obesity.
Purnama CA, Meiliana A, Barliana MI, Lestari K, Wijaya A., Free PMC Article | 04/3/2024 |
| MiR-145 Alleviates Sepsis-Induced Inflammatory Responses and Organ Injury by Targeting ADAM17. | MiR-145 Alleviates Sepsis-Induced Inflammatory Responses and Organ Injury by Targeting ADAM17.
Lin Y, Liu L, Lin Y, Yang R, Liao S, Xu M, He J, Liu Q. | 03/1/2024 |
| Tumor-derived exosomal ADAM17 promotes pre-metastatic niche formation by enhancing vascular permeability in colorectal cancer. | Tumor-derived exosomal ADAM17 promotes pre-metastatic niche formation by enhancing vascular permeability in colorectal cancer.
Li K, Xue W, Lu Z, Wang S, Zheng J, Lu K, Li M, Zong Y, Xu F, Dai J, Yang Y, Sun J., Free PMC Article | 02/29/2024 |
| Expression of ADAM17 and its clinical value for patients with pernicious placenta previa: A retrospective study of 148 PPP patients underwent cesarean section. | Expression of ADAM17 and its clinical value for patients with pernicious placenta previa: A retrospective study of 148 PPP patients underwent cesarean section.
Huang X, Wang X, Xiao X, Li J, Yuan H, Hou L., Free PMC Article | 02/27/2024 |
| m[6]A-modified HOXC10 promotes HNSCC progression via co-activation of ADAM17/EGFR and Wnt/beta-catenin signaling. | m(6)A‑modified HOXC10 promotes HNSCC progression via co‑activation of ADAM17/EGFR and Wnt/β‑catenin signaling.
Zhou Y, Huang Q, Wu C, Xu Y, Guo Y, Yuan X, Xu C, Zhou L., Free PMC Article | 01/10/2024 |
| The protease ADAM17 at the crossroads of disease: revisiting its significance in inflammation, cancer, and beyond. | The protease ADAM17 at the crossroads of disease: revisiting its significance in inflammation, cancer, and beyond.
Saad MI, Jenkins BJ. | 01/4/2024 |
| Neuraminidase-induced externalization of phosphatidylserine activates ADAM17 and impairs insulin signaling in endothelial cells. | Neuraminidase-induced externalization of phosphatidylserine activates ADAM17 and impairs insulin signaling in endothelial cells.
Ferreira-Santos L, Ramirez-Perez FI, Foote CA, Augenreich MA, McMillan NJ, Williams MB, Gonzalez-Vallejo JD, Power G, Wheeler AA, Manrique-Acevedo C, Martinez-Lemus LA, Padilla J., | 01/3/2024 |
| Predictive Roles of ADAM17 in Patient Survival and Immune Cell Infiltration in Hepatocellular Carcinoma. | Predictive Roles of ADAM17 in Patient Survival and Immune Cell Infiltration in Hepatocellular Carcinoma.
Ding T, Yu Y, Gao L, Xiang L, Xu B, Gu B, Chen H., Free PMC Article | 12/20/2023 |
| Genetic Predisposition to Elevated Levels of Circulating ADAM17 Is Associated with the Risk of Severe COVID-19. | Genetic Predisposition to Elevated Levels of Circulating ADAM17 Is Associated with the Risk of Severe COVID-19.
Pan M, Goncalves I, Edsfeldt A, Sun J, Swärd P., Free PMC Article | 11/18/2023 |
| The estrogen/miR-338-3p/ADAM17 axis enhances the viability of breast cancer cells via suppressing NK cell's function. | The estrogen/miR-338-3p/ADAM17 axis enhances the viability of breast cancer cells via suppressing NK cell's function.
Shi Y, Pan J, Hang C, Tan L, Hu L, Yan Z, Zhu J. | 10/20/2023 |
| The basis of complications in the context of SARS-CoV-2 infection: Pathological activation of ADAM17. | The basis of complications in the context of SARS-CoV-2 infection: Pathological activation of ADAM17.
Jiang S, Yang H, Sun Z, Zhang Y, Li Y, Li J. | 10/2/2023 |
| miR-4299 inhibits tumor progression in pancreatic cancer through targeting ADAM17. | miR-4299 inhibits tumor progression in pancreatic cancer through targeting ADAM17.
Liu J, Ye L, Lin K, Zhong T, Luo J, Wang T, Suo L, Mo Q, Li S, Chen Q, Yu Y. | 08/24/2023 |
| EGFR stimulation enables IL-6 trans-signalling via iRhom2-dependent ADAM17 activation in mammary epithelial cells. | EGFR stimulation enables IL-6 trans-signalling via iRhom2-dependent ADAM17 activation in mammary epithelial cells.
Schumacher N, Thomsen I, Brundert F, Hejret V, Düsterhöft S, Tichý B, Schmidt-Arras D, Voss M, Rose-John S. | 08/20/2023 |
| ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways. | ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways.
Rubina A, Patel M, Nightingale K, Potts M, Fielding CA, Kollnberger S, Lau B, Ladell K, Miners KL, Nichols J, Nobre L, Roberts D, Trinca TM, Twohig JP, Vlahava VM, Davison AJ, Price DA, Tomasec P, Wilkinson GWG, Weekes MP, Stanton RJ, Wang ECY., Free PMC Article | 08/16/2023 |
| Ectodomain Shedding by ADAM17 Increases the Release of Soluble CD40 from Human Endothelial Cells under Pro-Inflammatory Conditions. | Ectodomain Shedding by ADAM17 Increases the Release of Soluble CD40 from Human Endothelial Cells under Pro-Inflammatory Conditions.
Klersy A, Meyer S, Leuschner F, Kessler T, Hecker M, Wagner AH., Free PMC Article | 08/14/2023 |
| ADAM17 Aggravates the Inflammatory Response by Modulating Microglia Polarization Through the TGF-beta1/Smad Pathway Following Experimental Traumatic Brain Injury. | ADAM17 Aggravates the Inflammatory Response by Modulating Microglia Polarization Through the TGF-β1/Smad Pathway Following Experimental Traumatic Brain Injury.
Chen X, Yao J, Lai J, Lin L, Chen Y, Lin Y, Fang W, Ding C, Kang D. | 07/17/2023 |
| Investigation of CD56, ADAM17 and FGF21 Expressions in the Placentas of Preeclampsia Cases. | Investigation of CD56, ADAM17 and FGF21 Expressions in the Placentas of Preeclampsia Cases.
Darka Aslan I, Sel G, Barut F, Baser Acikgoz R, Balci S, Ozmen U, Barut A, Harma M, Harma MI., Free PMC Article | 07/7/2023 |
| ARPC5 is transcriptionally activated by KLF4, and promotes cell migration and invasion in prostate cancer via up-regulating ADAM17 : ARPC5 serves as an oncogene in prostate cancer. | ARPC5 is transcriptionally activated by KLF4, and promotes cell migration and invasion in prostate cancer via up-regulating ADAM17 : ARPC5 serves as an oncogene in prostate cancer.
Qu G, Zhang Y, Duan H, Tang C, Yang G, Chen D, Xu Y. | 06/13/2023 |
| ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression. | ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression.
Yang JT, Lee IN, Huang C, Huang HC, Wu YP, Chong ZY, Chen JC., Free PMC Article | 05/19/2023 |