| Human antigen R transfers miRNA to Syntaxin 5 to synergize miRNA export from activated macrophages. | Human antigen R transfers miRNA to Syntaxin 5 to synergize miRNA export from activated macrophages.
Hom Choudhury S, Bhattacharjee S, Mukherjee K, Bhattacharyya SN., Free PMC Article | 05/24/2024 |
| Syntaxin 5 determines Weibel-Palade body size and von Willebrand factor secretion by controlling Golgi architecture. | Syntaxin 5 determines Weibel-Palade body size and von Willebrand factor secretion by controlling Golgi architecture.
Kat M, Karampini E, Hoogendijk AJ, Bürgisser PE, Mulder AA, Van Alphen FPJ, Olins J, Geerts D, Van den Biggelaar M, Margadant C, Voorberg J, Bierings R., Free PMC Article | 08/6/2022 |
| Congenital disorder of glycosylation caused by starting site-specific variant in syntaxin-5. | Congenital disorder of glycosylation caused by starting site-specific variant in syntaxin-5.
Linders PTA, Gerretsen ECF, Ashikov A, Vals MA, de Boer R, Revelo NH, Arts R, Baerenfaenger M, Zijlstra F, Huijben K, Raymond K, Muru K, Fjodorova O, Pajusalu S, Õunap K, Ter Beest M, Lefeber D, van den Bogaart G., Free PMC Article | 01/1/2022 |
| Golgin45-Syntaxin5 Interaction Contributes to Structural Integrity of the Golgi Stack. | Golgin45-Syntaxin5 Interaction Contributes to Structural Integrity of the Golgi Stack.
Tiwari N, Graham M, Liu X, Yue X, Zhu L, Meshram D, Choi S, Qian Y, Rothman JE, Lee I., Free PMC Article | 10/24/2020 |
| Expression of the Syn5 K270R mutant in cells impairs post-mitotic Golgi reassembly | Monoubiquitination of Syntaxin 5 Regulates Golgi Membrane Dynamics during the Cell Cycle.
Huang S, Tang D, Wang Y., Free PMC Article | 06/24/2017 |
| Together, these data strongly suggest that syntaxin 5-mediated retrograde transport to the Golgi apparatus is a broadly conserved feature of adeno-associated virus trafficking. | Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction.
Nonnenmacher ME, Cintrat JC, Gillet D, Weber T., Free PMC Article | 04/11/2015 |
| Stx5 might play a role in modulating VLDL-R physiology by participating in an abrasively described or completely novel Golgi-bypass pathway. | Stx5 is a novel interactor of VLDL-R to affect its intracellular trafficking and processing.
Wagner T, Dieckmann M, Jaeger S, Weggen S, Pietrzik CU. | 09/21/2013 |
| serum anti-STX5 autoantibody, which was discovered by a proteomic approach, is a potential new serum marker for the diagnosis of endometriosis. | Identification of anti-syntaxin 5 autoantibody as a novel serum marker of endometriosis.
Nabeta M, Abe Y, Takaoka Y, Kusanagi Y, Ito M. | 12/31/2011 |
| Depletion of syntaxin-5 complex components results in the accumulation of autophagosomes as a result of lysosomal dysfunction, leading to decreased degradation of autophagic substrates. | Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex.
Renna M, Schaffner C, Winslow AR, Menzies FM, Peden AA, Floto RA, Rubinsztein DC., Free PMC Article | 08/6/2011 |
| Study shows that the SM protein, Sly1, interacts directly with the conserved oligomeric Golgi (COG) tethering complex; Sly1-COG interaction is mediated by the Cog4 subunit, which also interacts with Syntaxin 5 through a different binding site. | Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing.
Laufman O, Kedan A, Hong W, Lev S., Free PMC Article | 01/21/2010 |
| depletion of GM130 by RNA interference slows the rate of ER to Golgi trafficking in vivo; interactions of GM130 with syntaxin 5 and Rab1 are regulated by mitotic phosphorylation | Coordination of golgin tethering and SNARE assembly: GM130 binds syntaxin 5 in a p115-regulated manner.
Diao A, Frost L, Morohashi Y, Lowe M. | 01/21/2010 |
| hypothesize that syntaxin 5 also has trafficking-independent functions | Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins.
Amessou M, Fradagrada A, Falguières T, Lord JM, Smith DC, Roberts LM, Lamaze C, Johannes L., Free PMC Article | 01/21/2010 |
| Syx5 is required for the maintenance of the Golgi structures but may not play a major role in the transport of vesicles carrying proteins between the ER and the Golgi compartment. | RNA interference-mediated silencing of the syntaxin 5 gene induces Golgi fragmentation but capable of transporting vesicles.
Suga K, Hattori H, Saito A, Akagawa K. | 01/21/2010 |