| Striatin Gene Variants Are Associated With Salt Sensitivity of Blood Pressure by Mechanisms That Differ in Women and Men. | Striatin Gene Variants Are Associated With Salt Sensitivity of Blood Pressure by Mechanisms That Differ in Women and Men.
Gholami SK, Heydarpour M, Williams JS, Pojoga LH, Adler GK, Williams GH, Romero JR., | 01/29/2024 |
| Placental expression of striatin & endothelial nitric oxide synthase in women with & without pre-eclampsia. | Placental expression of striatin & endothelial nitric oxide synthase in women with & without pre-eclampsia.
Viveka M, Chaturvedula L, Ram AK, Vairappan B., Free PMC Article | 06/14/2023 |
| Phosphorylation of Influenza A Virus Matrix Protein 1 at Threonine 108 Controls Its Multimerization State and Functional Association with the STRIPAK Complex. | Phosphorylation of Influenza A Virus Matrix Protein 1 at Threonine 108 Controls Its Multimerization State and Functional Association with the STRIPAK Complex.
Liu L, Weber A, Linne U, Shehata M, Pleschka S, Kracht M, Schmitz ML., Free PMC Article | 03/2/2023 |
| ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy. | ULK1 phosphorylation of striatin activates protein phosphatase 2A and autophagy.
Hu Z, Sankar DS, Vu B, Leytens A, Vionnet C, Wu W, Stumpe M, Martínez-Martínez E, Stork B, Dengjel J. | 02/12/2022 |
| Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design. | Striatin genotype-based, mineralocorticoid receptor antagonist-driven clinical trial: study rationale and design.
Stone IB, Green JAEM, Koefoed AW, Hornik ES, Williams JS, Adler GK, Williams GH., Free PMC Article | 10/2/2021 |
| we detected novel and related STRN-NTRK3 and STRN3-NTRK3 fusions in 2 fibrosarcomas that occurred in the bone and soft tissue of young adult patients | Novel NTRK3 Fusions in Fibrosarcomas of Adults.
Yamazaki F, Nakatani F, Asano N, Wakai S, Sekimizu M, Mitani S, Kubo T, Kawai A, Ichikawa H, Yoshida A. | 01/18/2020 |
| STRN-ALK gene fusion is associated with radiation-associated Thyroid Cancer. | Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer.
Efanov AA, Brenner AV, Bogdanova TI, Kelly LM, Liu P, Little MP, Wald AI, Hatch M, Zurnadzy LY, Nikiforova MN, Drozdovitch V, Leeman-Neill R, Mabuchi K, Tronko MD, Chanock SJ, Nikiforov YE., Free PMC Article | 03/2/2019 |
| E2 enhanced HUVEC migration, which was inhibited by silencing striatin. In conclusion, our results demonstrated that E2-mediated upregulation of striatin promotes cell migration in HUVECs. | 17β-estradiol upregulates striatin protein levels via Akt pathway in human umbilical vein endothelial cells.
Zheng S, Sun P, Liu H, Li R, Long L, Xu Y, Chen S, Xu J., Free PMC Article | 02/9/2019 |
| striatin-associated Salt Sensitive Blood Pressure is associated with normal plasma renin activity and reduced epinephrine levels | Striatin Gene Polymorphic Variants Are Associated With Salt Sensitive Blood Pressure in Normotensives and Hypertensives.
Gupta T, Connors M, Tan JW, Manosroi W, Ahmed N, Ting PY, Garza AE, Romero JR, Hopkins PN, Williams JS, Williams GH., Free PMC Article | 08/4/2018 |
| The prevalence of STRN-ALK kinase fusions were determined in papillary thyroid cancer of an adult population | ETV6-NTRK3 and STRN-ALK kinase fusions are recurrent events in papillary thyroid cancer of adult population.
Bastos AU, de Jesus AC, Cerutti JM. | 01/13/2018 |
| In this review, we summarize the current understanding of the assembly and functions of STRIPAK complexes( striatin-centered multicomponent supramolecular structures containing both kinases and phosphatases), with a special focus on cell signaling and cancer | STRIPAK complexes in cell signaling and cancer.
Shi Z, Jiao S, Zhou Z. | 09/2/2017 |
| we report 2 cases of renal cell carcinomas harboring a novel STRN-ALK fusion | Two Cases of Renal Cell Carcinoma Harboring a Novel STRN-ALK Fusion Gene.
Kusano H, Togashi Y, Akiba J, Moriya F, Baba K, Matsuzaki N, Yuba Y, Shiraishi Y, Kanamaru H, Kuroda N, Sakata S, Takeuchi K, Yano H. | 07/22/2017 |
| the "multimodulator" scaffold roles of striatins in the initiation and regulation of the formation of various complex particles and structures, are discussed. | Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral adherens junctions in cultures of epithelia- and carcinoma-derived cells.
Franke WW, Rickelt S, Zimbelmann R, Dörflinger Y, Kuhn C, Frey N, Heid H, Rosin-Arbesfeld R., Free PMC Article | 11/21/2015 |
| PP2A/striatin complex modulates microtubule dynamics by regulating MAP2 phosphorylation | Downregulation of striatin leads to hyperphosphorylation of MAP2, induces depolymerization of microtubules and inhibits proliferation of HEK293T cells.
Kaźmierczak-Barańska J, Pęczek Ł, Przygodzka P, Cieślak MJ. | 04/4/2015 |
| the rapid, nongenomic mineralocorticoid receptor pathway (mediated via striatin) has a role in modulating the interaction between salt intake and blood pressure. | Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans.
Garza AE, Rariy CM, Sun B, Williams J, Lasky-Su J, Baudrand R, Yao T, Moize B, Hafiz WM, Romero JR, Adler GK, Ferri C, Hopkins PN, Pojoga LH, Williams GH., Free PMC Article | 02/28/2015 |
| A recurrent STRN/ALK fusion found in thyroid carcinomas. | Identification of a recurrent STRN/ALK fusion in thyroid carcinomas.
Pérot G, Soubeyran I, Ribeiro A, Bonhomme B, Savagner F, Boutet-Bouzamondo N, Hostein I, Bonichon F, Godbert Y, Chibon F., Free PMC Article | 10/4/2014 |
| Our data demonstrate that STRN-ALK fusion occurs in a subset of patients with highly aggressive types of thyroid cancer and provide initial evidence suggesting that it may represent a therapeutic target for these patients. | Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer.
Kelly LM, Barila G, Liu P, Evdokimova VN, Trivedi S, Panebianco F, Gandhi M, Carty SE, Hodak SP, Luo J, Dacic S, Yu YP, Nikiforova MN, Ferris RL, Altschuler DL, Nikiforov YE., Free PMC Article | 05/31/2014 |
| Striatin orchestrates the regulation of Mst3 by PP2A. | Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3.
Gordon J, Hwang J, Carrier KJ, Jones CA, Kern QL, Moreno CS, Karas RH, Pallas DC., Free PMC Article | 03/17/2012 |
| Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. | Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
Martins-de-Souza D, Gattaz WF, Schmitt A, Rewerts C, Maccarrone G, Dias-Neto E, Turck CW. | 01/28/2009 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesGene variants associated with ischemic stroke: the cardiovascular health study.
Luke MM, O'Meara ES, Rowland CM, Shiffman D, Bare LA, Arellano AR, Longstreth WT Jr, Lumley T, Rice K, Tracy RP, Devlin JJ, Psaty BM. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.
Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP, Ellis SG, Tracy RP, Devlin JJ, Psaty BM. | 12/3/2008 |
| Taken together, splicing variation of SG2NA might have some critical roles in differentiation and maturation in metazoan cells. | WD-40 repeat protein SG2NA has multiple splice variants with tissue restricted and growth responsive properties.
Sanghamitra M, Talukder I, Singarapu N, Sindhu KV, Kateriya S, Goswami SK. | 01/21/2010 |
| identify striatin as a molecular scaffold required for rapid, nongenomic estrogen-mediated activation of downstream signaling pathways | Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha.
Lu Q, Pallas DC, Surks HK, Baur WE, Mendelsohn ME, Karas RH., Free PMC Article | 01/21/2010 |