| Elevated expression of Aurora-A/AURKA in breast cancer associates with younger age and aggressive features. | Elevated expression of Aurora-A/AURKA in breast cancer associates with younger age and aggressive features.
Ingebriktsen LM, Humlevik ROC, Svanøe AA, Sæle AKM, Winge I, Toska K, Kalvenes MB, Davidsen B, Heie A, Knutsvik G, Askeland C, Stefansson IM, Hoivik EA, Akslen LA, Wik E., Free PMC Article | 09/11/2024 |
| Transcription Factor ETV4 Activates AURKA to Promote PD-L1 Expression and Mediate Immune Escape in Lung Adenocarcinoma. | Transcription Factor ETV4 Activates AURKA to Promote PD-L1 Expression and Mediate Immune Escape in Lung Adenocarcinoma.
Yang P, He S, Ye L, Weng H. | 09/9/2024 |
| Aurora Kinase A Is Overexpressed in Human Retinoblastoma and Correlates with Histopathologic High-Risk Factors: Implications for Targeted Therapy. | Aurora Kinase A Is Overexpressed in Human Retinoblastoma and Correlates with Histopathologic High-Risk Factors: Implications for Targeted Therapy.
Borah NA, Mittal R, Sucharita S, Rath S, Kaliki S, Patnaik S, Tripathy D, Reddy MM. | 08/31/2024 |
| Hsa_circRNA_007630 knockdown delays colon cancer progression by modulation of ferroptosis via miR-506-3p/AURKA axis. | Hsa_circRNA_007630 knockdown delays colon cancer progression by modulation of ferroptosis via miR-506-3p/AURKA axis.
Hu Y, Wu X, Tan X, Zhang J. | 07/22/2024 |
| Involvement of Endolysosomes and Aurora Kinase A in the Regulation of Amyloid beta Protein Levels in Neurons. | Involvement of Endolysosomes and Aurora Kinase A in the Regulation of Amyloid β Protein Levels in Neurons.
Afghah Z, Khan N, Datta G, Halcrow PW, Geiger JD, Chen X., Free PMC Article | 06/25/2024 |
| SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation. | SOX9 is regulated by AURKA in response to Helicobacter pylori infection via EIF4E-mediated cap-dependent translation.
Gomaa A, Maacha S, Peng D, Soutto M, Genoula M, Bhat N, Cao L, Zhu S, Castells A, Chen Z, Zaika A, McDonald OG, El-Rifai W., | 06/20/2024 |
| AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis. | AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis.
Deng B, Liu F, Chen N, Li X, Lei J, Chen N, Wu J, Wang X, Lu J, Fang M, Chen A, Zhang Z, He B, Yan M, Zhang Y, Wang Z, Liu Q., Free PMC Article | 04/17/2024 |
| AURKA Enhances the Glycolysis and Development of Ovarian Endometriosis Through ERbeta. | AURKA Enhances the Glycolysis and Development of Ovarian Endometriosis Through ERβ.
Sun Y, Zhang S, Zhang X, Li G, Sun F, Wang M, Ren C, Jiang A, Yang T. | 03/21/2024 |
| AURKA inhibition induces Ewing's sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis. | AURKA inhibition induces Ewing's sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis.
Chen H, Hu J, Xiong X, Chen H, Lin B, Chen Y, Li Y, Cheng D, Li Z., Free PMC Article | 02/7/2024 |
| The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m[6]A-dependent stabilization of AURKA mRNA. | The PIN1-YTHDF1 axis promotes breast tumorigenesis via the m(6)A-dependent stabilization of AURKA mRNA.
Shrestha P, Kim G, Kang H, Bhattarai PY, Choi HS. | 01/16/2024 |
| An emerging biomarker for the diagnosis and treatment of esophageal squamous cell carcinoma - Aurora A. | An emerging biomarker for the diagnosis and treatment of esophageal squamous cell carcinoma - Aurora A.
Zhou W, Guo S, Zhang J, Yan Y, Wu J, Liu X. | 01/12/2024 |
| Combined Aurora Kinase A and CHK1 Inhibition Enhances Radiosensitivity of Triple-Negative Breast Cancer Through Induction of Apoptosis and Mitotic Catastrophe Associated With Excessive DNA Damage. | Combined Aurora Kinase A and CHK1 Inhibition Enhances Radiosensitivity of Triple-Negative Breast Cancer Through Induction of Apoptosis and Mitotic Catastrophe Associated With Excessive DNA Damage.
Li C, Liao J, Wang X, Chen FX, Guo X, Chen X. | 11/20/2023 |
| Computational completion of the Aurora interaction region of N-Myc in the Aurora a kinase complex. | Computational completion of the Aurora interaction region of N-Myc in the Aurora a kinase complex.
Altiner P, Çınaroğlu SS, Timucin AC, Timucin E., Free PMC Article | 11/15/2023 |
| CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly. | CENP-E activation by Aurora A and B controls kinetochore fibrous corona disassembly.
Eibes S, Rajendraprasad G, Guasch-Boldu C, Kubat M, Steblyanko Y, Barisic M., Free PMC Article | 09/7/2023 |
| E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA. | E2F1-mediated KDM4A-AS1 up-regulation promotes EMT of hepatocellular carcinoma cells by recruiting ILF3 to stabilize AURKA mRNA.
Shen HM, Zhang D, Xiao P, Qu B, Sun YF., Free PMC Article | 07/21/2023 |
| AURKA is a prognostic potential therapeutic target in skin cutaneous melanoma modulating the tumor microenvironment, apoptosis, and hypoxia. | AURKA is a prognostic potential therapeutic target in skin cutaneous melanoma modulating the tumor microenvironment, apoptosis, and hypoxia.
Long S, Zhang XF. | 07/7/2023 |
| Differential translation of mRNA isoforms underlies oncogenic activation of cell cycle kinase Aurora A. | Differential translation of mRNA isoforms underlies oncogenic activation of cell cycle kinase Aurora A.
Cacioppo R, Akman HB, Tuncer T, Erson-Bensan AE, Lindon C., Free PMC Article | 07/5/2023 |
| CDCA2 promotes melanoma progression by inhibiting ubiquitin-mediated degradation of Aurora kinase A. | CDCA2 promotes melanoma progression by inhibiting ubiquitin-mediated degradation of Aurora kinase A.
Sun W, Jin Y, Wei C, Xu Y, Liu W, Zhong J, Zou Z, Lin X, Xiang Y, Chen Y. | 06/25/2023 |
| Aurora A kinase inhibition compromises its antitumor efficacy by elevating PD-L1 expression. | Aurora A kinase inhibition compromises its antitumor efficacy by elevating PD-L1 expression.
Wang X, Huang J, Liu F, Yu Q, Wang R, Wang J, Zhu Z, Yu J, Hou J, Shim JS, Jiang W, Li Z, Zhang Y, Dang Y., Free PMC Article | 05/8/2023 |
| STIL/AURKA axis promotes cell proliferation by influencing primary cilia formation in bladder cancer. | STIL/AURKA axis promotes cell proliferation by influencing primary cilia formation in bladder cancer.
Li J, Qi Y, Li B, Liu Y, Yang K, Zhang Z, Zhu J, Du E., Free PMC Article | 05/3/2023 |
| The involvement of Aurora-A and p53 in oxaliplatin-resistant colon cancer cells. | The involvement of Aurora-A and p53 in oxaliplatin-resistant colon cancer cells.
Chen MC, Yang BZ, Kuo WW, Wu SH, Wang TF, Yeh YL, Chen MC, Huang CY. | 04/20/2023 |
| Phospho PTEN mediated dephosphorylation of mitotic kinase PLK1 and Aurora Kinase A prevents aneuploidy and preserves genomic stability. | Phospho PTEN mediated dephosphorylation of mitotic kinase PLK1 and Aurora Kinase A prevents aneuploidy and preserves genomic stability.
Ghosh G, Misra S, Ray R, Chowdhury SG, Karmakar P. | 04/19/2023 |
| The promotion action of AURKA on post-ischemic angiogenesis in diabetes-related limb ischemia. | The promotion action of AURKA on post-ischemic angiogenesis in diabetes-related limb ischemia.
Bai T, Li M, Liu Y, Qiao Z, Zhang X, Wang Y, Wang Z., Free PMC Article | 04/1/2023 |
| AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation. | AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.
Asteriti IA, Polverino F, Stagni V, Sterbini V, Ascanelli C, Naso FD, Mastrangelo A, Rosa A, Paiardini A, Lindon C, Guarguaglini G., Free PMC Article | 02/22/2023 |
| CCNB1 and AURKA are critical genes for prostate cancer progression and castration-resistant prostate cancer resistant to vinblastine. | CCNB1 and AURKA are critical genes for prostate cancer progression and castration-resistant prostate cancer resistant to vinblastine.
Chen X, Ma J, Wang X, Zi T, Qian D, Li C, Xu C., Free PMC Article | 01/14/2023 |