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    STIM1 stromal interaction molecule 1 [ Homo sapiens (human) ]

    Gene ID: 6786, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Adaptation of STIM1 structure-function relationships for optogenetic control of calcium signaling.

    Adaptation of STIM1 structure-function relationships for optogenetic control of calcium signaling.
    Zhuang Z, Meng Y, Xue Y, Wang Y, Cheng X, Jing J., Free PMC Article

    10/17/2024
    STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration.

    STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration.
    Hammad AS, Yu F, Al-Hamaq J, Horgen FD, Machaca K.

    10/1/2024
    The effect of genetic polymorphisms in STIM1 and ORAI1 on erythropoietin resistance in Egyptian patients with end-stage renal disease.

    The effect of genetic polymorphisms in STIM1 and ORAI1 on erythropoietin resistance in Egyptian patients with end-stage renal disease.
    Gomaa AAE, Zeid AMA, Nagy IM, Zahran AM.

    09/14/2024
    The miR-641-STIM1 and SATB1 axes play important roles in the regulation of the Th17/Treg balance in ITP.

    The miR-641-STIM1 and SATB1 axes play important roles in the regulation of the Th17/Treg balance in ITP.
    Zhu H, Ruan X, Zhao K, Kuang W, Liu S, Yan W, Fu X, Cheng Z, Li R, Peng H., Free PMC Article

    08/13/2024
    Role of STIM1 in stretch-induced signaling in human airway smooth muscle.

    Role of STIM1 in stretch-induced signaling in human airway smooth muscle.
    Yao Y, Zheng M, Borkar NA, Thompson MA, Zhang EY, Koloko Ngassie ML, Wang S, Pabelick CM, Vogel ER, Prakash YS.

    07/16/2024
    Essential role of N-terminal SAM regions in STIM1 multimerization and function.

    Essential role of N-terminal SAM regions in STIM1 multimerization and function.
    Sallinger M, Humer C, Ong HL, Narayanasamy S, Lin QT, Fahrner M, Grabmayr H, Berlansky S, Choi S, Schmidt T, Maltan L, Atzgerstorfer L, Niederwieser M, Frischauf I, Romanin C, Stathopulos PB, Ambudkar I, Leitner R, Bonhenry D, Schindl R.,

    07/16/2024
    Association of HLA class II gene polymorphisms and expression levels of ORAI1/STIM1 genes in HIV-1-positive patients with HIV-related dermatoses in Latvia.

    Association of HLA class II gene polymorphisms and expression levels of ORAI1/STIM1 genes in HIV-1‒positive patients with HIV-related dermatoses in Latvia.
    Soha A, Azina I, Miskina DA, Murasko V, Zolovs M, Rubins A.

    07/15/2024
    Insights into the dynamics of the Ca2+ release-activated Ca2+ channel pore-forming complex Orai1.

    Insights into the dynamics of the Ca2+ release-activated Ca2+ channel pore-forming complex Orai1.
    Fröhlich M, Söllner J, Derler I.

    06/25/2024
    STIM1 translocation to the nucleus protects cells from DNA damage.

    STIM1 translocation to the nucleus protects cells from DNA damage.
    Sanchez-Lopez I, Orantos-Aguilera Y, Pozo-Guisado E, Alvarez-Barrientos A, Lilla S, Zanivan S, Lachaud C, Martin-Romero FJ., Free PMC Article

    03/25/2024
    STIM1 regulates pancreatic beta-cell behaviour: A modelling study.

    STIM1 regulates pancreatic β-cell behaviour: A modelling study.
    Romero-Campos HE, Dupont G, González-Vélez V.

    03/18/2024
    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation.

    The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation.
    Carreras-Sureda A, Zhang X, Laubry L, Brunetti J, Koenig S, Wang X, Castelbou C, Hetz C, Liu Y, Frieden M, Demaurex N.

    01/5/2024
    Role of STIM1 in the Regulation of Cardiac Energy Substrate Preference.

    Role of STIM1 in the Regulation of Cardiac Energy Substrate Preference.
    Liu P, Yang Z, Wang Y, Sun A., Free PMC Article

    09/14/2023
    Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature.

    Molecular dynamics simulations reveal the hidden EF-hand of EF-SAM as a possible key thermal sensor for STIM1 activation by temperature.
    Neamtu A, Serban DN, Barritt GJ, Isac DL, Vasiliu T, Laaksonen A, Serban IL., Free PMC Article

    09/1/2023
    Chronic suppression of STIM1-mediated calcium signaling in Purkinje cells rescues the cerebellar pathology in spinocerebellar ataxia type 2.

    Chronic suppression of STIM1-mediated calcium signaling in Purkinje cells rescues the cerebellar pathology in spinocerebellar ataxia type 2.
    Egorova PA, Marinina KS, Bezprozvanny IB.

    05/22/2023
    The roles and mechanism of STIM1 in tumorigenesis and metastasis.

    The roles and mechanism of STIM1 in tumorigenesis and metastasis.
    Yan CH, Bai WY, Zhang ZM, Shen JL, Wang YJ, Sun JW.

    05/18/2023
    CAPN1 (Calpain1)-Dependent Cleavage of STIM1 (Stromal Interaction Molecule 1) Results in an Enhanced SOCE (Store-Operated Calcium Entry) in Human Neonatal Platelets.

    CAPN1 (Calpain1)-Dependent Cleavage of STIM1 (Stromal Interaction Molecule 1) Results in an Enhanced SOCE (Store-Operated Calcium Entry) in Human Neonatal Platelets.
    Berna-Erro A, Ramesh G, Delgado E, Corbacho AJ, Ferrer-Marín F, Teruel R, Granados MP, Rosado JA, Redondo PC.

    05/15/2023
    Knockdown of Stromal Interaction Molecule 1 (STIM1) Suppresses Acute Myeloblastic Leukemia-M5 Cell Line Survival Through Inhibition of Reactive Oxygen Species Activities.

    Knockdown of Stromal Interaction Molecule 1 (STIM1) Suppresses Acute Myeloblastic Leukemia-M5 Cell Line Survival Through Inhibition of Reactive Oxygen Species Activities.
    Algariri ES, Mydin RBSMN, Moses EJ, Okekpa SI, Rahim NAA, Yusoff NM., Free PMC Article

    03/3/2023
    Swing-out opening of stromal interaction molecule 1.

    Swing-out opening of stromal interaction molecule 1.
    Horvath F, Berlansky S, Maltan L, Grabmayr H, Fahrner M, Derler I, Romanin C, Renger T, Krobath H., Free PMC Article

    03/1/2023
    Stromal Interaction Molecule 1 (STIM1) is a Potential Prognostic Biomarker and Correlates with Immune Infiltrates in Solid Tumors.

    Stromal Interaction Molecule 1 (STIM1) is a Potential Prognostic Biomarker and Correlates with Immune Infiltrates in Solid Tumors.
    Zhang Z, Wang Z, Liu Y, Zhao L, Fu W.

    02/14/2023
    STIM1 and ORAI1 form a novel cold transduction mechanism in sensory and sympathetic neurons.

    STIM1 and ORAI1 form a novel cold transduction mechanism in sensory and sympathetic neurons.
    Buijs TJ, Vilar B, Tan CH, McNaughton PA., Free PMC Article

    02/11/2023
    The miRNA-185-5p/STIM1 Axis Regulates the Invasiveness of Nasopharyngeal Carcinoma Cell Lines by Modulating EGFR Activation-Stimulated Switch from E- to N-Cadherin.

    The miRNA-185-5p/STIM1 Axis Regulates the Invasiveness of Nasopharyngeal Carcinoma Cell Lines by Modulating EGFR Activation-Stimulated Switch from E- to N-Cadherin.
    Luo Y, Ye J, Deng Y, Huang Y, Liu X, He Q, Chen Y, Li Q, Lin Y, Liang R, Li Y, Wei J, Zhang J., Free PMC Article

    01/28/2023
    MITF is a novel transcriptional regulator of the calcium sensor STIM1: Significance in physiological melanogenesis.

    MITF is a novel transcriptional regulator of the calcium sensor STIM1: Significance in physiological melanogenesis.
    Tanwar J, Sharma A, Saurav S, Shyamveer, Jatana N, Motiani RK., Free PMC Article

    01/14/2023
    Subcellular compartmentalization of STIM1 for the distinction of Darier disease from Hailey-Hailey disease.

    Subcellular compartmentalization of STIM1 for the distinction of Darier disease from Hailey-Hailey disease.
    Stanisz H, Mitteldorf C, Janning H, Bennemann A, Schön MP, Frank J.

    12/24/2022
    Functional Role of STIM-1 and Orai1 in Human Microvascular Aging.

    Functional Role of STIM-1 and Orai1 in Human Microvascular Aging.
    El Assar M, García-Rojo E, Sevilleja-Ortiz A, Sánchez-Ferrer A, Fernández A, García-Gómez B, Romero-Otero J, Rodríguez-Mañas L, Angulo J., Free PMC Article

    12/3/2022
    Nuanced Interactions between AKAP79 and STIM1 with Orai1 Ca[2+] Channels at Endoplasmic Reticulum-Plasma Membrane Junctions Sustain NFAT Activation.

    Nuanced Interactions between AKAP79 and STIM1 with Orai1 Ca(2+) Channels at Endoplasmic Reticulum-Plasma Membrane Junctions Sustain NFAT Activation.
    Lin YP, Scappini E, Landaverde C, Parekh-Glitsch F, Tucker CJ, Mirams GR, Parekh AB., Free PMC Article

    11/26/2022
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