| Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study. | Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study.
Stetskaya TA, Krapiva AB, Kobzeva KA, Gurtovoy DE, Komkova GV, Polonikov AV, Bushueva OY. | 03/31/2024 |
| An autophagy-related model of 4 key genes for predicting prognosis of patients with laryngeal cancer. | An autophagy-related model of 4 key genes for predicting prognosis of patients with laryngeal cancer.
Luo MS, Huang GJ, Liu HB., Free PMC Article | 09/5/2020 |
| A novel susceptibility gene, ST13, coding for a cochaperone of the glucocorticoid receptor, is associated with exacerbations in asthmatic children and young adults despite their ICS use. | ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.
Vijverberg SJ, Koster ES, Tavendale R, Leusink M, Koenderman L, Raaijmakers JA, Postma DS, Koppelman GH, Turner SW, Mukhopadhyay S, Tse SM, Tantisira KG, Hawcutt DB, Francis B, Pirmohamed M, Pino-Yanes M, Eng C, Burchard EG, Palmer CN, Maitland-van der Zee AH., Free PMC Article | 02/13/2016 |
| St13 is a proliferation regulator that inhibits tumor growth in colorectal neoplasms and may affect cell migration. | ST13, a proliferation regulator, inhibits growth and migration of colorectal cancer cell lines.
Bai R, Shi Z, Zhang JW, Li D, Zhu YL, Zheng S., Free PMC Article | 08/31/2013 |
| Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase. | Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase.
Su CH, Wang CY, Lan KH, Li CP, Chao Y, Lin HC, Lee SD, Lee WP. | 12/31/2011 |
| A single amino acid substitution (L211S) resulted in a loss of Hip function. This mutation also appears to disrupt the interaction of Hip with Hsp70 in vitro | Single-point mutation in a conserved TPR domain of Hip disrupts enhancement of glucocorticoid receptor signaling.
Place SP., Free PMC Article | 12/3/2011 |
| Hip has been identified as a novel substrate of GRK5 in vitro and in cells, and phosphorylation of Hip by GRK5 plays a role in modulating CXCR4 internalization | G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4.
Barker BL, Benovic JL., Free PMC Article | 10/22/2011 |
| These results strongly indicate ST13 mediated by adenovirus triggers colorectal cell apoptosis via ASK1-JNK signaling cascade | ASK1-JNK signaling cascade mediates Ad-ST13-induced apoptosis in colorectal HCT116 cells.
Yang M, Yu M, Guan D, Gu J, Cao X, Wang W, Zheng S, Xu Y, Shen Z, Liu X. | 08/23/2010 |
| S-nitrosoglutathione corrects DeltaF508 CFTR trafficking by inhibiting Hop expression | Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy.
Marozkina NV, Yemen S, Borowitz M, Liu L, Plapp M, Sun F, Islam R, Erdmann-Gilmore P, Townsend RR, Lichti CF, Mantri S, Clapp PW, Randell SH, Gaston B, Zaman K., Free PMC Article | 07/26/2010 |
| The expression levels of ST13 cannot serve as a biomarker for early stages of PD. | Expression analysis of suppression of tumorigenicity 13 gene in patients with Parkinson's disease.
Shadrina MI, Filatova EV, Karabanov AV, Slominsky PA, Illarioshkin SN, Ivanova-Smolenskaya IA, Limborska SA. | 05/31/2010 |
| analysis of similarity between the chloroplast translocon component, Tic40, and the human co-chaperone, Hsp70-interacting protein | Functional similarity between the chloroplast translocon component, Tic40, and the human co-chaperone, Hsp70-interacting protein (Hip).
Bédard J, Kubis S, Bimanadham S, Jarvis P. | 01/21/2010 |
| results suggest that granzyme B-mediated loss of HIP expression occurs in vivo, and in a coordinate fashion with loss of BID, pro-caspase-8 and pro-caspase-3; data implicate the Hsp70 co-chaperone HIP in the proteolytic cascade of some apoptotic pathways | Proteolysis of HIP during apoptosis occurs within a region similar to the BID loop.
Caruso JA, Reiners JJ Jr. | 01/21/2010 |
| The expression of ST13 decreases in colorectal cancer tissue compared with that in adjacent normal tissue. ST13 is mostly expressed in colorectal epithelia and adenocarcinoma cells. | Expression of ST13 in colorectal cancer and adjacent normal tissues.
Wang LB, Zheng S, Zhang SZ, Peng JP, Ye F, Fang SC, Wu JM., Free PMC Article | 01/21/2010 |
| tetratricopeptide repeat domain is required for effects of CHIP on alpha-synuclein inclusion morphology, number of inclusions, and proteasomal degradation as well as the direct interaction of CHIP with Hsp70 implicates their cooperation in these processes | The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways.
Shin Y, Klucken J, Patterson C, Hyman BT, McLean PJ. | 01/21/2010 |
| Hip functions to promote the efficiency of glucocorticoid receptor maturation in cells | The heat shock protein 70 cochaperone hip enhances functional maturation of glucocorticoid receptor.
Nelson GM, Prapapanich V, Carrigan PE, Roberts PJ, Riggs DL, Smith DF. | 01/21/2010 |
| The expression levels of the ST13 gene were significantly decreased in primary tumors compared with adjacent mucosa (P<0.05). | Evaluation of ST13 gene expression in colorectal cancer patients.
Dong QH, Zheng S, Hu Y, Chen GX, Ding JY., Free PMC Article | 01/21/2010 |