The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis. | The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis. Zhao W, Ouyang C, Zhang L, Wang J, Zhang J, Zhang Y, Huang C, Xiao Q, Jiang B, Lin F, Zhang C, Zhu M, Xie C, Huang X, Zhang B, Zhao W, He J, Chen S, Liu X, Lin D, Li Q, Wang Z., Free PMC Article | 09/9/2024 |
Human pannexin 1 channel is not phosphorylated by Src tyrosine kinase at Tyr199 and Tyr309. | Human pannexin 1 channel is not phosphorylated by Src tyrosine kinase at Tyr199 and Tyr309. Ruan Z, Lee J, Li Y, Du J, Lü W., Free PMC Article | 09/4/2024 |
Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis. | Early-stage lung cancer is driven by a transitional cell state dependent on a KRAS-ITGA3-SRC axis. Moye AL, Dost AF, Ietswaart R, Sengupta S, Ya V, Aluya C, Fahey CG, Louie SM, Paschini M, Kim CF., Free PMC Article | 08/13/2024 |
Role of the GRP78-c-Src signaling pathway on osteoblast differentiation of periodontal ligament fibroblasts induced by cyclic mechanical stretch. | Role of the GRP78-c-Src signaling pathway on osteoblast differentiation of periodontal ligament fibroblasts induced by cyclic mechanical stretch. Hu J, Cui Z, Huang K, Su R, Zhao S., Free PMC Article | 08/12/2024 |
Regulation of Src tumor activity by its N-terminal intrinsically disordered region. | Regulation of Src tumor activity by its N-terminal intrinsically disordered region. Aponte E, Lafitte M, Sirvent A, Simon V, Barbery M, Fourgous E, Boublik Y, Maffei M, Armand F, Hamelin R, Pannequin J, Fort P, Pons M, Roche S., Free PMC Article | 07/26/2024 |
FAXC interacts with ANXA2 and SRC in mitochondria and promotes tumorigenesis in cholangiocarcinoma. | FAXC interacts with ANXA2 and SRC in mitochondria and promotes tumorigenesis in cholangiocarcinoma. Fujimori H, Shima-Nakamura M, Kanno SI, Shibuya-Takahashi R, Mochizuki M, Mizuma M, Unno M, Wakui Y, Abue M, Iwai W, Fukushi D, Satoh K, Yamaguchi K, Shindo N, Yasuda J, Tamai K., Free PMC Article | 07/8/2024 |
LINC08148 promotes the caveola-mediated endocytosis of Zika virus through upregulating transcription of Src. | LINC08148 promotes the caveola-mediated endocytosis of Zika virus through upregulating transcription of Src. Huo Z, Zhu X, Peng Q, Chen C, Yang X, Huang C, Xiang Y, Tian Q, Liu J, Liu C, Zhang P., | 06/14/2024 |
Oxidative Stress Participates in Age-Related Cataract Formation by Disrupting Connection between Lens Epithelial Cells through c-Src/VEGF Pathway. | Oxidative Stress Participates in Age-Related Cataract Formation by Disrupting Connection between Lens Epithelial Cells through c-Src/VEGF Pathway. Zhang L, Zhang ZF, Hui YN, He F, Guan XR, Zhou J. | 03/25/2024 |
ING3 inhibits the malignant progression of lung adenocarcinoma by negatively regulating ITGB4 expression to inactivate Src/FAK signaling. | ING3 inhibits the malignant progression of lung adenocarcinoma by negatively regulating ITGB4 expression to inactivate Src/FAK signaling. Cheng S, Li M, Zheng W, Li C, Hao Z, Dai Y, Wang J, Zhuo J, Zhang L. | 03/14/2024 |
Superbinder based phosphoproteomic landscape revealed PRKCD_pY313 mediates the activation of Src and p38 MAPK to promote TNBC progression. | Superbinder based phosphoproteomic landscape revealed PRKCD_pY313 mediates the activation of Src and p38 MAPK to promote TNBC progression. Deng Y, Hou Z, Li Y, Yi M, Wu Y, Zheng Y, Yang F, Zhong G, Hao Q, Zhai Z, Wang M, Ma X, Kang H, Ji F, Dong C, Liu H, Dai Z., Free PMC Article | 02/20/2024 |
TIMP2 ameliorates blood-brain barrier disruption in traumatic brain injury by inhibiting Src-dependent VE-cadherin internalization. | TIMP2 ameliorates blood-brain barrier disruption in traumatic brain injury by inhibiting Src-dependent VE-cadherin internalization. Tang J, Kang Y, Zhou Y, Shang N, Li X, Wang H, Lan J, Wang S, Wu L, Peng Y., Free PMC Article | 02/9/2024 |
c-Src regulates delta-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6. | c-Src regulates δ-secretase activation and truncated Tau production by phosphorylating the E3 ligase Traf6. Jiang Y, Li L, Wu R, Wu L, Zhang B, Wang JZ, Liu R, Liu F, Wang J, Wang X., Free PMC Article | 01/31/2024 |
Compartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma. | Compartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma. Herrington CS, Oswald AJ, Stillie LJ, Croy I, Churchman M, Hollis RL., Free PMC Article | 01/29/2024 |
An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function. | An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function. Cuesta-Hernández HN, Contreras J, Soriano-Maldonado P, Sánchez-Wandelmer J, Yeung W, Martín-Hurtado A, Muñoz IG, Kannan N, Llimargas M, Muñoz J, Plaza-Menacho I., Free PMC Article | 10/24/2023 |
Identification and functional validation of SRC and RAPGEF1 as new direct targets of miR-203, involved in regulation of epidermal homeostasis. | Identification and functional validation of SRC and RAPGEF1 as new direct targets of miR-203, involved in regulation of epidermal homeostasis. Golebiewski C, Gastaldi C, Vieu DL, Mari B, Rezzonico R, Bernerd F, Marionnet C., Free PMC Article | 09/12/2023 |
The activated CD36-Src axis promotes lung adenocarcinoma cell proliferation and actin remodeling-involved metastasis in high-fat environment. | The activated CD36-Src axis promotes lung adenocarcinoma cell proliferation and actin remodeling-involved metastasis in high-fat environment. Liu LZ, Wang B, Zhang R, Wu Z, Huang Y, Zhang X, Zhou J, Yi J, Shen J, Li MY, Dong M., Free PMC Article | 08/25/2023 |
SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway. | SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway. Xu R, Song J, Ruze R, Chen Y, Yin X, Wang C, Zhao Y., Free PMC Article | 08/9/2023 |
The c-Src/LIST Positive Feedback Loop Sustains Tumor Progression and Chemoresistance. | The c-Src/LIST Positive Feedback Loop Sustains Tumor Progression and Chemoresistance. Wang X, Wang B, Li F, Li X, Guo T, Gao Y, Wang D, Huang W., Free PMC Article | 07/28/2023 |
PELP1 and SRC kinase as important molecules in the estrogen-mediated pathway in human testis and epididymis. | PELP1 and SRC kinase as important molecules in the estrogen-mediated pathway in human testis and epididymis. Skibińska I, Andrusiewicz M, Jendraszak M, Żbikowska A, Żaba C, Kotwicka M. | 06/23/2023 |
MiR-654-3p targets SRC to suppress tumor growth in non-small cell lung cancer. | MiR-654-3p targets SRC to suppress tumor growth in non-small cell lung cancer. Pang M, Jiang Y, Huang Y, Ren B, He L, Jiang L. | 06/22/2023 |
Casein kinase 1 controls the shuttling of epidermal growth factor receptor and estrogen receptor in endometrial carcinoma induced by breast cancer hormonal therapy: Relevance of GPER1/Src. | Casein kinase 1 controls the shuttling of epidermal growth factor receptor and estrogen receptor in endometrial carcinoma induced by breast cancer hormonal therapy: Relevance of GPER1/Src. Hoang LN, Lee SJ. | 06/14/2023 |
FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC. | FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC. Chen X, Chen J, Feng W, Huang W, Wang G, Sun M, Luo X, Wang Y, Nie Y, Fan D, Wu K, Xia L., Free PMC Article | 03/21/2023 |
Expression of estrogen receptors, PELP1, and SRC in human spermatozoa and their associations with semen quality. | Expression of estrogen receptors, PELP1, and SRC in human spermatozoa and their associations with semen quality. Skibińska I, Andrusiewicz M, Jendraszak M, Żbikowska A, Jędrzejczak P, Kotwicka M., Free PMC Article | 02/28/2023 |
Disordered Domain Shifts the Conformational Ensemble of the Folded Regulatory Domain of the Multidomain Oncoprotein c-Src. | Disordered Domain Shifts the Conformational Ensemble of the Folded Regulatory Domain of the Multidomain Oncoprotein c-Src. Gurumoorthy V, Shrestha UR, Zhang Q, Pingali SV, Boder ET, Urban VS, Smith JC, Petridis L, O'Neill H. | 02/22/2023 |
Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer. | Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer. Zou H, Luo J, Guo Y, Tong T, Liu Y, Chen Y, Xiao Y, Ye L, Zhu C, Deng L, Wang B, Pan Y, Li P., Free PMC Article | 02/11/2023 |