| SPRR3 Contributes to Aggressiveness of Pancreatic Cancer Cells via NF-kappaB Signaling Pathway. | SPRR3 Contributes to Aggressiveness of Pancreatic Cancer Cells via NF-κB Signaling Pathway.
Xie Y, Li H, Zhong B, Zhu X, Ye R, Xie B, Zhang J., Free PMC Article | 02/11/2023 |
| Small Proline-Rich Protein 3 Regulates IL-33/ILC2 Axis to Promote Allergic Airway Inflammation. | Small Proline-Rich Protein 3 Regulates IL-33/ILC2 Axis to Promote Allergic Airway Inflammation.
Zhu G, Cai H, Ye L, Mo Y, Zhu M, Zeng Y, Song X, Yang C, Gao X, Wang J, Jin M., Free PMC Article | 02/26/2022 |
| Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes. | Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes.
Bae JE, Choi H, Shin DW, Na HW, Park NY, Kim JB, Jo DS, Cho MJ, Lyu JH, Chang JH, Lee EH, Lee TR, Kim HJ, Cho DH., Free PMC Article | 09/19/2020 |
| SPRR3v2 mRNA level in non-lesional AD skin correlated with severity of AD, and SPRR3 protein level in non-lesional AD skin correlated inversely with pruritus. | Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype.
Trzeciak M, Sakowicz-Burkiewicz M, Wesserling M, Dobaczewska D, Gleń J, Nowicki R, Pawelczyk T. | 01/28/2017 |
| Results implicate that SPRR3 might serve as a radiation-sensitive predictor of ESCC. | Small proline-rich repeat protein 3 enhances the sensitivity of esophageal cancer cells in response to DNA damage-induced apoptosis.
Luo A, Chen H, Ding F, Zhang Y, Wang M, Xiao Z, Liu Z., Free PMC Article | 04/19/2014 |
| This study demonstrates that SPRR3 promotes BC cell proliferation by enhancing p53 degradation via the AKT and MAPK pathways | Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer.
Kim JC, Yu JH, Cho YK, Jung CS, Ahn SH, Gong G, Kim YS, Cho DH. | 11/17/2012 |
| The quantitative analysis of SPRR3 mRNA is a robust and reliable method to monitor the malignant transformation of the healthy esophageal mucosa into esophageal squamous cell carcinoma. | Quantitative evaluation of SPRR3 expression in esophageal squamous cell carcinoma by qPCR and its potential use as a biomarker.
de A Simão T, Souza-Santos PT, de Oliveira DS, Bernardo V, Lima SC, Rapozo DC, Kruel CD, Faria PA, Ribeiro Pinto LF, Albano RM. | 11/26/2011 |
| The SPRR3 variant associated with eczema carried an extra 24-bp repeat in the central domain, which may alter the physical properties of the cornified cell envelope | Association screening in the Epidermal Differentiation Complex (EDC) identifies an SPRR3 repeat number variant as a risk factor for eczema.
Marenholz I, Rivera VA, Esparza-Gordillo J, Bauerfeind A, Lee-Kirsch MA, Ciechanowicz A, Kurek M, Piskackova T, Macek M, Lee YA. | 10/8/2011 |
| Results suggest that increased expression of SPRR3 is involved in colorectal tumorigenesis. | Upregulation of SPRR3 promotes colorectal tumorigenesis.
Cho DH, Jo YK, Roh SA, Na YS, Kim TW, Jang SJ, Kim YS, Kim JC., Free PMC Article | 11/13/2010 |
| two isoforms of SPRR3 were characterized from saliva of preterm human newborn and autoptic fetal oral mucosa, parotid and submandibular gland samples. | Characterization of two isoforms of human SPRR3 from saliva of preterm human newborn and autoptic fetal oral mucosa, parotid and submandibular gland samples.
Manconi B, Cabras T, Pisano E, Nemolato S, Inzitari R, Iavarone F, Fanali C, Sanna MT, Tirone C, Vento G, Romagnoli C, Faa G, Castagnola M, Messana I. | 09/13/2010 |
| Sciellin, SPRR3, and periplakin transcripts were all upregulated (4.67-, 4.95-, 2.77-fold, respectively) by prolonged exposure to cyclic strain (24-72 h), but not at earlier time points. | Biomechanical stress induces novel arterial intima-enriched genes: implications for vascular adaptation to stress.
Pyle AL, Li B, Maupin AB, Guzman RJ, Crimmins DL, Olson S, Atkinson JB, Young PP., Free PMC Article | 05/10/2010 |
| Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. | Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families.
Kainu K, Kivinen K, Zucchelli M, Suomela S, Kere J, Inerot A, Baker BS, Powles AV, Fry L, Samuelsson L, Saarialho-Kere U. | 05/7/2010 |
| These data suggest that SPRR3 may play a role in vascular smooth muscle cells adaptation to local biomechanical stress within the plaque microenvironment. | Regulation of the atheroma-enriched protein, SPRR3, in vascular smooth muscle cells through cyclic strain is dependent on integrin alpha1beta1/collagen interaction.
Pyle AL, Atkinson JB, Pozzi A, Reese J, Eckes B, Davidson JM, Crimmins DL, Young PP., Free PMC Article | 01/21/2010 |
| Esophagin/SPRR3 may play a role in the maintenance of normal esophageal epithelial homeostasis, and aberrant expression of Esophagin/SPRR3 may contribute to the tumorigenesis of esophageal squamous cell carcinoma | Exogenous expression of Esophagin/SPRR3 attenuates the tumorigenicity of esophageal squamous cell carcinoma cells via promoting apoptosis.
Zhang Y, Feng YB, Shen XM, Chen BS, Du XL, Luo ML, Cai Y, Han YL, Xu X, Zhan QM, Wang MR. | 01/21/2010 |
| A marker of human esophageal neoplastic progression | Esophagin and proliferating cell nuclear antigen (PCNA) are biomarkers of human esophageal neoplastic progression.
Kimos MC, Wang S, Borkowski A, Yang GY, Yang CS, Perry K, Olaru A, Deacu E, Sterian A, Cottrell J, Papadimitriou J, Sisodia L, Selaru FM, Mori Y, Xu Y, Yin J, Abraham JM, Meltzer SJ. | 01/21/2010 |
| SPR3 transcripts were significantly increased in human papillomavirus 11-infected tissues and minimally increased in human papillomavirus 59-infected tissues | Infection with Human Papillomavirus alters expression of the small proline rich proteins 2 and 3.
Lehr E, Hohl D, Huber M, Brown D. | 01/21/2010 |