| Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer. | Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer.
Kong R, Patel AS, Sato T, Jiang F, Yoo S, Bao L, Sinha A, Tian Y, Fridrikh M, Liu S, Feng J, He X, Jiang J, Ma Y, Grullon K, Yang D, Powell CA, Beasley MB, Zhu J, Snyder EL, Li S, Watanabe H., Free PMC Article | 12/24/2022 |
| Is hypermethylation of SOX1 gene an independent prognostic marker in surgically resected non-small cell lung cancer? | Is hypermethylation of SOX1 gene an independent prognostic marker in surgically resected non-small cell lung cancer?
Kontic M, Jovanovic D, Kern I, Nelson HH, Bojic S, Ognjanovic M, Ognjanovic S. | 12/3/2022 |
| Study of the influence of NGF-beta gene overexpression in human mesenchymal stem cells on the expression level of SOX1 and neural pathway genes. | Study of the influence of NGF-β gene overexpression in human mesenchymal stem cells on the expression level of SOX1 and neural pathway genes.
Morys J, Borkowska P, Zielinska A, Kowalski J. | 07/16/2022 |
| Discordant SOX-1 antibodies results in paraneoplastic Lambert-Eaton syndrome diagnosis by the clinical laboratory. | Discordant SOX-1 antibodies results in paraneoplastic Lambert-Eaton syndrome diagnosis by the clinical laboratory.
Pozo-Giraldez A, Rodríguez-Borja E, Diaz-Gimenez M, Carratala-Calvo A, Magro-Pose P, Perez-Griera J. | 01/1/2022 |
| In Silico Identification of SOX1 Post-Translational Modifications Highlights a Shared Protein Motif. | In Silico Identification of SOX1 Post-Translational Modifications Highlights a Shared Protein Motif.
Ahmad A, Strohbuecker S, Scotti C, Tufarelli C, Sottile V., Free PMC Article | 06/19/2021 |
| SOX1 and PAX1 Are Hypermethylated in Cervical Adenocarcinoma and Associated with Better Prognosis. | SOX1 and PAX1 Are Hypermethylated in Cervical Adenocarcinoma and Associated with Better Prognosis.
Zhao Z, Zhang X, Zhao X, Cai J, Wu NY, Wang J., Free PMC Article | 06/12/2021 |
| SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway. | SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway.
Lei XX, Liu Y, Wang JX, Cai Q, Yan M, He HP, Liu Q, Long ZJ, Guan Z., Free PMC Article | 03/20/2021 |
| The methylation levels ofPAX1, SOX1 and ZNF582 genes were all higher in cancer tissues. | Aberrant DNA methylation of PAX1, SOX1 and ZNF582 genes as potential biomarkers for esophageal squamous cell carcinoma.
Tang L, Liou YL, Wan ZR, Tang J, Zhou Y, Zhuang W, Wang G. | 04/11/2020 |
| a methylation-specific expression gene of cervical adenocarcinoma | Tumor-suppressor gene SOX1 is a methylation-specific expression gene in cervical adenocarcinoma.
Yuan M, Yao L, Abulizi G., Free PMC Article | 10/12/2019 |
| Data show that high levels of SRY-box transcription factor 1 (SOX1) observed in a subset of patients correlate with lower overall survival, and suggest SOX1 as a potential target in the glioma stem cells (GSCs) population in glioblastoma. | Oncogenic activity of SOX1 in glioblastoma.
Garcia I, Aldaregia J, Marjanovic Vicentic J, Aldaz P, Moreno-Cugnon L, Torres-Bayona S, Carrasco-Garcia E, Garros-Regulez L, Egaña L, Rubio A, Pollard S, Stevanovic M, Sampron N, Matheu A., Free PMC Article | 08/10/2019 |
| aberrant methylation of SOX1 and VIM promoters may be potential biomarkers for noninvasive detection of hepatocellular carcinoma and metastasis | Methylation of SOX1 and VIM promoters in serum as potential biomarkers for hepatocellular carcinoma.
Liu XY, Fan YC, Gao S, Zhao J, Chen LY, Li F, Wang K. | 04/27/2019 |
| SOX1 overlapping transcript was found to be highly expressed in differentiated neural stem cells across different time points of differentiation, and its expression correlated with SOX1 gene expression. | Expression of a SOX1 overlapping transcript in neural differentiation and cancer models.
Ahmad A, Strohbuecker S, Tufarelli C, Sottile V., Free PMC Article | 10/28/2017 |
| The sensitivity was found to be 62% and 83% for DAPK1 and SOX1, respectively, when analyzed separately in the singleplex assay, but increased to 90% in the multiplex assay when either or both of the SOX1 and the DAPK1 gene promoters showed methylation. | Development of a multiplex MethyLight assay for the detection of DAPK1 and SOX1 methylation in epithelial ovarian cancer in a north Indian population.
Kaur M, Singh A, Singh K, Gupta S, Sachan M. | 02/18/2017 |
| Taken together, these data suggest that SOX1 can function as a tumor suppressor partly by interfering with Wnt/beta-catenin signaling in breast cancer. | SOX1 inhibits breast cancer cell growth and invasion through suppressing the Wnt/β-catenin signaling pathway.
Song L, Liu D, He J, Wang X, Dai Z, Zhao Y, Kang H, Wang B. | 01/28/2017 |
| the under-expression of SOX1 was associated significantly with SALL4 overexpression. This study was the first to evaluate SOX1 underexpression and its association with poor prognosis in esophageal squamous cell carcinoma. | SOX1 is correlated to stemness state regulator SALL4 through progression and invasiveness of esophageal squamous cell carcinoma.
Rad A, Esmaeili Dizghandi S, Abbaszadegan MR, Taghechian N, Najafi M, Forghanifard MM. | 01/28/2017 |
| The results of the SRY gene amplification of plasma DNA from pregnant women was the same as that of the amniocyte DNA | Isolation and analysis of cell-free fetal DNA from maternal peripheral blood in Chinese women.
Yang WC, Zhu L, Qiu YM, Zhou BX, Cheng JL, Wei CL, Chen HC, Li LY, Fu XD, Fu JJ. | 10/22/2016 |
| The analysis identified a signaling axis between FGF signaling and the transcription factor Sox1, which is preferentially expressed in stem- and mesenchymal-like breast cancers. | Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells.
Dravis C, Spike BT, Harrell JC, Johns C, Trejo CL, Southard-Smith EM, Perou CM, Wahl GM., Free PMC Article | 07/16/2016 |
| downregulation of SOX-1 was correlated with poor prognosis and tumor development in hepatocellular carcinoma. | Prognostic significance of SOX-1 expression in human hepatocelluar cancer.
Lou J, Zhang K, Chen J, Gao Y, Wang R, Chen LB., Free PMC Article | 05/28/2016 |
| SOX 1 suppressed cell growth and invasion in Tu212 cells by inhibiting Wnt pathway, and the anti-tumor effect of SOX 1 could be weakened by SOX 2, which may be a potential molecular basis for clinical treatment of laryngeal squamous cell carcinoma . | SOX 1, contrary to SOX 2, suppresses proliferation, migration, and invasion in human laryngeal squamous cell carcinoma by inhibiting the Wnt/β-catenin pathway.
Yang N, Wang Y, Hui L, Li X, Jiang X. | 04/16/2016 |
| Our results suggest that SOX1 is epigenetically silenced in the majority of NSCLC and restoration of SOX1 inhibited cell migration by regulating actin cytoskeletal remodeling in NSCLC. | Epigenetic inactivation of SOX1 promotes cell migration in lung cancer.
Li N, Li S. | 10/24/2015 |
| SOX1 decreases the expression of beta-catenin in a proteasome-independent manner. | SOX1 down-regulates β-catenin and reverses malignant phenotype in nasopharyngeal carcinoma.
Guan Z, Zhang J, Wang J, Wang H, Zheng F, Peng J, Xu Y, Yan M, Liu B, Cui B, Huang Y, Liu Q., Free PMC Article | 07/25/2015 |
| PAX1 and SOX1 DNA methylation correlate with a cervical intraepithelial neoplasia diagnosis. | PAX1/SOX1 DNA methylation and cervical neoplasia detection: a Taiwanese Gynecologic Oncology Group (TGOG) study.
Lai HC, Ou YC, Chen TC, Huang HJ, Cheng YM, Chen CH, Chu TY, Hsu ST, Liu CB, Hung YC, Wen KC, Yu MH, Wang KL., Free PMC Article | 04/4/2015 |
| we successfully established a three-step inducing protocol to derive Neural stem cells from adipose-derived mesenchymal stem cells with high purity by Sox1 activation | Generation of highly purified neural stem cells from human adipose-derived mesenchymal stem cells by Sox1 activation.
Feng N, Han Q, Li J, Wang S, Li H, Yao X, Zhao RC., Free PMC Article | 10/18/2014 |
| The methylation index of SOX1 recovered from scrapings of uterine cervix adenocarcinomas is significantly higher than in normal controls. | High methylation rate of LMX1A, NKX6-1, PAX1, PTPRR, SOX1, and ZNF582 genes in cervical adenocarcinoma.
Chang CC, Huang RL, Wang HC, Liao YP, Yu MH, Lai HC. | 10/18/2014 |
| Taken together, these data suggest that SOX1 can function as a tumor suppressor partly by interfering with Wnt/beta-catenin signaling in cervical cancer. | SOX1 suppresses cell growth and invasion in cervical cancer.
Lin YW, Tsao CM, Yu PN, Shih YL, Lin CH, Yan MD. | 12/28/2013 |