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    SOD2 superoxide dismutase 2 [ Homo sapiens (human) ]

    Gene ID: 6648, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Investigation of the association between the CASP8rs1045485 and SOD2 rs4880 single nucleotide polymorphisms (SNPs) with breast cancer.

    Investigation of the association between the CASP8rs1045485 and SOD2 rs4880 single nucleotide polymorphisms (SNPs) with breast cancer.
    Shikholeslami SR, Keshavarzi F.

    10/10/2024
    Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.

    Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
    Azadmanesh J, Slobodnik K, Struble LR, Lutz WE, Coates L, Weiss KL, Myles DAA, Kroll T, Borgstahl GEO., Free PMC Article

    08/14/2024
    Superoxide dismutase 2 scavenges ROS to promote osteogenic differentiation of human periodontal ligament stem cells by regulating Smad3 in alveolar bone-defective rats.

    Superoxide dismutase 2 scavenges ROS to promote osteogenic differentiation of human periodontal ligament stem cells by regulating Smad3 in alveolar bone-defective rats.
    Qiu W, Sun Q, Li N, Chen Z, Wu H, Chen Z, Guo X, Fang F.

    07/19/2024
    SOD2 promotes the immunosuppressive function of mesenchymal stem cells at the expense of adipocyte differentiation.

    SOD2 promotes the immunosuppressive function of mesenchymal stem cells at the expense of adipocyte differentiation.
    Li Y, Wang T, Li X, Li W, Lei Y, Shang Q, Zheng Z, Fang J, Cao L, Yu D, Meng Z, Zhang S, Liu R, Liu C, Xu C, Ding Y, Chen Y, Candi E, Melino G, Wang Y, Shi Y, Shao C.,

    04/11/2024
    SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential.

    SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential.
    Tamagawa S, Sakai D, Nojiri H, Nakamura Y, Warita T, Matsushita E, Schol J, Soma H, Ogasawara S, Munesada D, Koike M, Shimizu T, Sato M, Ishijima M, Watanabe M., Free PMC Article

    04/1/2024
    Variants rs2758346, rs5746094, and rs2758331 of SOD2 gene: association study with breast cancer in a Mexican population and their analysis in silico.

    Variants rs2758346, rs5746094, and rs2758331 of SOD2 gene: association study with breast cancer in a Mexican population and their analysis in silico.
    Gallegos-Arreola MP, Garibaldi-Ríos AF, Figuera LE, Salas-Aragón A, Gómez-Meda BC, Zúñiga-González GM, Delgado-Saucedo JI, Rivera-Cameras A, Dávalos-Rodriguez IP, Ruiz-Ramírez AV, Puebla-Pérez AM.

    03/27/2024
    Methyltransferase METTL3-mediated maturation of miR-4654 facilitates high glucose-induced apoptosis and oxidative stress in lens epithelial cells via decreasing SOD2.

    Methyltransferase METTL3-mediated maturation of miR-4654 facilitates high glucose-induced apoptosis and oxidative stress in lens epithelial cells via decreasing SOD2.
    Guo M, Su F, Chen Y, Su B.

    03/1/2024
    SOD2 confers anlotinib resistance via regulation of mitochondrial damage in OSCC.

    SOD2 confers anlotinib resistance via regulation of mitochondrial damage in OSCC.
    Li S, Cao C, Huang Z, Tang D, Chen J, Wang A, He Q.

    03/1/2024
    The impact of the association between Val16Ala-SOD2 SNP and SOD2 immunohistochemistry expression in the prognosis of patients with esophageal cancer.

    The impact of the association between Val16Ala-SOD2 SNP and SOD2 immunohistochemistry expression in the prognosis of patients with esophageal cancer.
    Dos Santos AV, Kaul AJ, Dos Santos GT, Dal Berto M, Manfroi LM, Rizzotto G, Roehe AV, Alves RCS, Lutz A, Beck P, Alves RJV, Cruz IBM, Bica CG.

    02/2/2024
    Overexpression of manganese superoxide dismutase mitigates ACL injury-induced muscle atrophy, weakness and oxidative damage.

    Overexpression of manganese superoxide dismutase mitigates ACL injury-induced muscle atrophy, weakness and oxidative damage.
    Latham CM, Balawender PJ, Thomas NT, Keeble AR, Brightwell CR, Ismaeel A, Wen Y, Fry JL, Sullivan PG, Johnson DL, Noehren B, Owen AM, Fry CS.,

    01/29/2024
    Association of a single nucleotide polymorphism in SOD2 with susceptibility for the development of diabetic nephropathy in patients with type 2 diabetes: A Saudi population study.

    Association of a single nucleotide polymorphism in SOD2 with susceptibility for the development of diabetic nephropathy in patients with type 2 diabetes: A Saudi population study.
    Sultan S, Alharbi M, Alrayes N, Makki N, Faruqui H, Basuni L, Alhozali A, Abdulnoor R, Borai A, Almalki A, Alzahrani A, Alamoudi R, Almaghrabi M., Free PMC Article

    11/16/2023
    Identification of the regulatory network and potential markers for type 2 diabetes mellitus related to internal exposure to metals in Chinese adults.

    Identification of the regulatory network and potential markers for type 2 diabetes mellitus related to internal exposure to metals in Chinese adults.
    Wang Y, Shi P, Zhao C, Shi J, Qi Z, Xu S, Wang X, Su N, Gao Z, Zhu J, He M.

    09/16/2023
    The role of SOD2 and NOS2 genes in the molecular aspect of bladder cancer pathophysiology.

    The role of SOD2 and NOS2 genes in the molecular aspect of bladder cancer pathophysiology.
    Grębowski R, Saluk J, Bijak M, Szemraj J, Wigner-Jeziorska P., Free PMC Article

    09/8/2023
    Association of SOD2 rs2758339, rs5746136 and rs2842980 polymorphisms with increased risk of breast cancer: a haplotype-based case-control study.

    Association of SOD2 rs2758339, rs5746136 and rs2842980 polymorphisms with increased risk of breast cancer: a haplotype-based case-control study.
    Asadi S, Abkar M, Zamanzadeh Z, Taghipour Kamalabad S, Sedghi M, Yousefnia S.

    08/22/2023
    Gene expression, levels and polymorphism (Ala16Val) of mitochondrial superoxide dismutase in tuberculosis patients of Rajasthan.

    Gene expression, levels and polymorphism (Ala16Val) of mitochondrial superoxide dismutase in tuberculosis patients of Rajasthan.
    Gauba K, Gupta S, Shekhawat J, Dutt N, Yadav D, Nag VL, Rao M, Sharma P, Banerjee M.

    08/11/2023
    Variation of the genes encoding antioxidant enzymes SOD2 (rs4880), GPX1 (rs1050450), and CAT (rs1001179) and susceptibility to male infertility: a genetic association study and in silico analysis.

    Variation of the genes encoding antioxidant enzymes SOD2 (rs4880), GPX1 (rs1050450), and CAT (rs1001179) and susceptibility to male infertility: a genetic association study and in silico analysis.
    Fallah F, Colagar AH, Saleh HA, Ranjbar M.

    08/10/2023
    Knockdown of circSOD2 ameliorates osteoarthritis progression via the miR-224-5p/PRDX3 axis.

    Knockdown of circSOD2 ameliorates osteoarthritis progression via the miR-224-5p/PRDX3 axis.
    Li H, Cao Y, Chang C, Huang W, Su S, Peng Z, Zhang J., Free PMC Article

    06/22/2023
    NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation.

    NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation.
    Su IC, Su YK, Setiawan SA, Yadav VK, Fong IH, Yeh CT, Lin CM, Liu HW., Free PMC Article

    05/19/2023
    FTO promotes Bortezomib resistance via m6A-dependent destabilization of SOD2 expression in multiple myeloma.

    FTO promotes Bortezomib resistance via m6A-dependent destabilization of SOD2 expression in multiple myeloma.
    Wang C, Li L, Li M, Wang W, Jiang Z.

    04/19/2023
    CircSOD2 Contributes to Tumor Progression, Immune Evasion and Anti-PD-1 Resistance in Hepatocellular Carcinoma by Targeting miR-497-5p/ANXA11 Axis.

    CircSOD2 Contributes to Tumor Progression, Immune Evasion and Anti-PD-1 Resistance in Hepatocellular Carcinoma by Targeting miR-497-5p/ANXA11 Axis.
    Ye R, Lu X, Liu J, Duan Q, Xiao J, Duan X, Yue Z, Liu F.

    04/6/2023
    Polymorphisms of Antioxidant Enzymes SOD2 (rs4880) and GPX1 (rs1050450) Are Associated with Bladder Cancer Risk or Its Aggressiveness.

    Polymorphisms of Antioxidant Enzymes SOD2 (rs4880) and GPX1 (rs1050450) Are Associated with Bladder Cancer Risk or Its Aggressiveness.
    Nikic P, Dragicevic D, Jerotic D, Savic S, Djukic T, Stankovic B, Kovacevic L, Simic T, Matic M., Free PMC Article

    01/28/2023
    Endothelial superoxide dismutase 2 is decreased in sickle cell disease and regulates fibronectin processing.

    Endothelial superoxide dismutase 2 is decreased in sickle cell disease and regulates fibronectin processing.
    Dosunmu-Ogunbi A, Yuan S, Shiwarski DJ, Tashman JW, Reynolds M, Feinberg A, Novelli EM, Shiva S, Straub AC., Free PMC Article

    01/14/2023
    Oxidative stress-related genes (EPHX1 and MnSOD) polymorphism and risk of pre-eclampsia: a meta-analysis.

    Oxidative stress-related genes (EPHX1 and MnSOD) polymorphism and risk of pre-eclampsia: a meta-analysis.
    Zhao G, Liu J, Meng T.

    11/26/2022
    Genetic polymorphism impact superoxide dismutase and glutathione peroxidase activity in charcoal workers.

    Genetic polymorphism impact superoxide dismutase and glutathione peroxidase activity in charcoal workers.
    Miglani K, Kumar S, Yadav A, Aggarwal N, Gupta R.

    11/5/2022
    The Association of Polymorphisms in Genes Encoding Antioxidant Enzymes GPX1 (rs1050450), SOD2 (rs4880) and Transcriptional Factor Nrf2 (rs6721961) with the Risk and Development of Prostate Cancer.

    The Association of Polymorphisms in Genes Encoding Antioxidant Enzymes GPX1 (rs1050450), SOD2 (rs4880) and Transcriptional Factor Nrf2 (rs6721961) with the Risk and Development of Prostate Cancer.
    Djokic M, Radic T, Santric V, Dragicevic D, Suvakov S, Mihailovic S, Stankovic V, Cekerevac M, Simic T, Nikitovic M, Coric V., Free PMC Article

    11/5/2022
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