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    SNAP25 synaptosome associated protein 25 [ Homo sapiens (human) ]

    Gene ID: 6616, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Neuronal-specific TNFAIP1 ablation attenuates postoperative cognitive dysfunction via targeting SNAP25 for K48-linked ubiquitination.

    Neuronal-specific TNFAIP1 ablation attenuates postoperative cognitive dysfunction via targeting SNAP25 for K48-linked ubiquitination.
    Wang W, Gao W, Gong P, Song W, Bu X, Hou J, Zhang L, Zhao B., Free PMC Article

    12/26/2023
    The Role of SNAP-25 in Autism Spectrum Disorders Onset Patterns.

    The Role of SNAP-25 in Autism Spectrum Disorders Onset Patterns.
    Bolognesi E, Guerini FR, Carta A, Chiappedi M, Sotgiu S, Mensi MM, Agliardi C, Zanzottera M, Clerici M., Free PMC Article

    09/30/2023
    Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults.

    Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults.
    Saloner R, Paolillo EW, Wojta KJ, Fonseca C, Gontrum EQ, Lario-Lago A, Rabinovici GD, Yokoyama JS, Rexach JE, Kramer JH, Casaletto KB., Free PMC Article

    08/11/2023
    Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.

    Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients.
    Yazar V, Kühlwein JK, Knehr A, Grozdanov V, Ekici AB, Ludolph AC, Danzer KM., Free PMC Article

    07/27/2023
    Role of SNAP25 on the occurrence and development of eosinophilic gastritis.

    Role of SNAP25 on the occurrence and development of eosinophilic gastritis.
    Zhang J, Hou S, Chi XQ, Shan HF, Li XW, Zhang QJ, Wang JL, Kang CB., Free PMC Article

    07/25/2023
    Non-coding variants in VAMP2 and SNAP25 affect gene expression: potential implications in migraine susceptibility.

    Non-coding variants in VAMP2 and SNAP25 affect gene expression: potential implications in migraine susceptibility.
    Felício D, Dias A, Martins S, Carvalho E, Lopes AM, Pinto N, Lemos C, Santos M, Alves-Ferreira M., Free PMC Article

    07/7/2023
    miR-23a-3p and miR-181a-5p modulate SNAP-25 expression.

    miR-23a-3p and miR-181a-5p modulate SNAP-25 expression.
    Agostini S, Bolognesi E, Mancuso R, Marventano I, Citterio LA, Guerini FR, Clerici M., Free PMC Article

    01/21/2023
    Investigation of possible associations of the BDNF, SNAP-25 and SYN III genes with the neurocognitive measures: BDNF and SNAP-25 genes might be involved in attention domain, SYN III gene in executive function.

    Investigation of possible associations of the BDNF, SNAP-25 and SYN III genes with the neurocognitive measures: BDNF and SNAP-25 genes might be involved in attention domain, SYN III gene in executive function.
    Bolat H, Ünsel-Bolat G, Özgül S, Parıltay E, Tahıllıoğlu A, Rohde LA, Akın H, Ercan ES.

    11/12/2022
    Role of SNAP-25 MnlI variant in impaired working memory and brain functions in attention deficit/hyperactivity disorder.

    Role of SNAP-25 MnlI variant in impaired working memory and brain functions in attention deficit/hyperactivity disorder.
    Fang D, Yang B, Wang P, Mo T, Gan Y, Liang G, Huang R, Zeng H., Free PMC Article

    10/22/2022
    Cerebrospinal Fluid Synaptosomal-Associated Protein 25 Levels in Patients with Alzheimer's Disease: A Meta-Analysis.

    Cerebrospinal Fluid Synaptosomal-Associated Protein 25 Levels in Patients with Alzheimer's Disease: A Meta-Analysis.
    Liu Q, Liu H, Zhang S, Yang Q, Shen L, Jiao B.

    09/17/2022
    Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer's disease.

    Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer's disease.
    Kivisäkk P, Carlyle BC, Sweeney T, Quinn JP, Ramirez CE, Trombetta BA, Mendes M, Brock M, Rubel C, Czerkowicz J, Graham D, Arnold SE., Free PMC Article

    05/14/2022
    Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via autophagy induction.

    Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via autophagy induction.
    Jung Y, Lee SE, Kang I, Cho SM, Kang KS, Kwon HJ., Free PMC Article

    04/16/2022
    Machine Learning Prediction of ADHD Severity: Association and Linkage to ADGRL3, DRD4, and SNAP25.

    Machine Learning Prediction of ADHD Severity: Association and Linkage to ADGRL3, DRD4, and SNAP25.
    Cervantes-Henríquez ML, Acosta-López JE, Martinez AF, Arcos-Burgos M, Puentes-Rozo PJ, Vélez JI.

    03/26/2022
    Effects of the SNAP25 on Integration Ability of Brain Functions in Children With ADHD.

    Effects of the SNAP25 on Integration Ability of Brain Functions in Children With ADHD.
    Yang Y, Peng G, Zeng H, Fang D, Zhang L, Xu S, Yang B.

    02/26/2022
    Family-based association study identifies SNAP25 as a susceptibility gene for autism in the Han Chinese population.

    Family-based association study identifies SNAP25 as a susceptibility gene for autism in the Han Chinese population.
    Wang Z, Li J, Zhang T, Lu T, Wang H, Jia M, Liu J, Xiong J, Zhang D, Wang L.

    01/1/2022
    Oligomeric alpha-Syn and SNARE complex proteins in peripheral extracellular vesicles of neural origin are biomarkers for Parkinson's disease.

    Oligomeric α-Syn and SNARE complex proteins in peripheral extracellular vesicles of neural origin are biomarkers for Parkinson's disease.
    Agliardi C, Meloni M, Guerini FR, Zanzottera M, Bolognesi E, Baglio F, Clerici M.

    12/11/2021
    Cognitively normal APOE epsilon4 carriers have specific elevation of CSF SNAP-25.

    Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25.
    Butt OH, Long JM, Henson RL, Herries E, Sutphen CL, Fagan AM, Cruchaga C, Ladenson JH, Holtzman DM, Morris JC, Ances BM, Schindler SE, Alzheimer's Disease Neuroimaging Initiative., Free PMC Article

    12/11/2021
    Sarcopenia associates with SNAP-25 SNPs and a miRNAs profile which is modulated by structured rehabilitation treatment.

    Sarcopenia associates with SNAP-25 SNPs and a miRNAs profile which is modulated by structured rehabilitation treatment.
    Agostini S, Mancuso R, Costa AS, Guerini FR, Trecate F, Miglioli R, Menna E, Arosio B, Clerici M, SA. M. B. A. project., Free PMC Article

    09/18/2021
    Amyloid-beta Peptides Disrupt Interactions Between VAMP-2 and SNAP-25 in Neuronal Cells as Determined by FRET/FLIM.

    Amyloid-β Peptides Disrupt Interactions Between VAMP-2 and SNAP-25 in Neuronal Cells as Determined by FRET/FLIM.
    Sharda N, Pengo T, Wang Z, Kandimalla KK.

    09/11/2021
    The role of synaptic biomarkers in the spectrum of neurodegenerative diseases.

    The role of synaptic biomarkers in the spectrum of neurodegenerative diseases.
    Mazzucchi S, Palermo G, Campese N, Galgani A, Della Vecchia A, Vergallo A, Siciliano G, Ceravolo R, Hampel H, Baldacci F.

    08/21/2021
    SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.

    SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes.
    Liang T, Qin T, Kang F, Kang Y, Xie L, Zhu D, Dolai S, Greitzer-Antes D, Baker RK, Feng D, Tuduri E, Ostenson CG, Kieffer TJ, Banks K, Pessin JE, Gaisano HY., Free PMC Article

    06/26/2021
    De novo variants in SNAP25 cause an early-onset developmental and epileptic encephalopathy.

    De novo variants in SNAP25 cause an early-onset developmental and epileptic encephalopathy.
    Klöckner C, Sticht H, Zacher P, Popp B, Babcock HE, Bakker DP, Barwick K, Bonfert MV, Bönnemann CG, Brilstra EH, Care4Rare Canada Consortium, Chung WK, Clarke AJ, Devine P, Donkervoort S, Fraser JL, Friedman J, Gates A, Ghoumid J, Hobson E, Horvath G, Keller-Ramey J, Keren B, Kurian MA, Lee V, Leppig KA, Lundgren J, McDonald MT, McLaughlin HM, McTague A, Mefford HC, Mignot C, Mikati MA, Nava C, Raymond FL, Sampson JR, Sanchis-Juan A, Shashi V, Shieh JTC, Shinawi M, Slavotinek A, Stödberg T, Stong N, Sullivan JA, Taylor AC, Toler TL, van den Boogaard MJ, van der Crabben SN, van Gassen KLI, van Jaarsveld RH, Van Ziffle J, Wadley AF, Wagner M, Wigby K, Wortmann SB, Zarate YA, Møller RS, Lemke JR, Platzer K.

    06/12/2021
    Association between SNAP25 and human glioblastoma multiform: a comprehensive bioinformatic analysis.

    Association between SNAP25 and human glioblastoma multiform: a comprehensive bioinformatic analysis.
    Yu C, Yin J, Wang X, Chen L, Wei Y, Lu C, You Y., Free PMC Article

    04/3/2021
    Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies.

    Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies.
    Alten B, Zhou Q, Shin OH, Esquivies L, Lin PY, White KI, Sun R, Chung WK, Monteggia LM, Brunger AT, Kavalali ET., Free PMC Article

    02/13/2021
    Relationship of SNAP25 variants with schizophrenia and antipsychotic-induced weight change in large-scale schizophrenia patients.

    Relationship of SNAP25 variants with schizophrenia and antipsychotic-induced weight change in large-scale schizophrenia patients.
    Guan F, Zhang T, Han W, Zhu L, Ni T, Lin H, Liu D, Chen G, Xiao J, Li T.

    01/23/2021
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