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    SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 [ Homo sapiens (human) ]

    Gene ID: 6602, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis.

    Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis.
    Zhao Y, Liu Y, Zhao G, Lu H, Liu Y, Xue C, Chang Z, Liu H, Deng Y, Liang W, Wang H, Rom O, Garcia-Barrio MT, Zhu T, Guo Y, Chang L, Lin J, Chen YE, Zhang J., Free PMC Article

    11/13/2023
    Integrated analysis reveals SMARCD1 is a potential biomarker and therapeutic target in skin cutaneous melanoma.

    Integrated analysis reveals SMARCD1 is a potential biomarker and therapeutic target in skin cutaneous melanoma.
    Chen J, Yu N, Ou S, Wang X, Li H, Zhu H.

    09/1/2023
    microRNA-99a-5p induces cellular senescence in gemcitabine-resistant bladder cancer by targeting SMARCD1.

    microRNA-99a-5p induces cellular senescence in gemcitabine-resistant bladder cancer by targeting SMARCD1.
    Tamai M, Tatarano S, Okamura S, Fukumoto W, Kawakami I, Osako Y, Sakaguchi T, Sugita S, Yonemori M, Yamada Y, Nakagawa M, Enokida H, Yoshino H., Free PMC Article

    04/23/2022
    Assembly and interaction of core subunits of BAF complexes and crystal study of the SMARCC1/SMARCE1 binary complex.

    Assembly and interaction of core subunits of BAF complexes and crystal study of the SMARCC1/SMARCE1 binary complex.
    Dong C, Zhang R, Xu L, Liu B, Chu X.

    03/19/2022
    Smarcd1 Inhibits the Malignant Phenotypes of Human Glioblastoma Cells via Crosstalk with Notch1.

    Smarcd1 Inhibits the Malignant Phenotypes of Human Glioblastoma Cells via Crosstalk with Notch1.
    Zhu Y, Wang H, Fei M, Tang T, Niu W, Zhang L., Free PMC Article

    10/30/2021
    NMR spectroscopy uncovers direct interaction between BAF60A and p53.

    NMR spectroscopy uncovers direct interaction between BAF60A and p53.
    Han J, Kim T, Moon S, Park JH, Lee W, Ko YJ, Ryu KS, Yun JH, Lee W.

    04/17/2021
    SMARCD1 is a transcriptional target of specific non-hotspot mutant p53 forms.

    SMARCD1 is a transcriptional target of specific non-hotspot mutant p53 forms.
    Adduri RSR, George SA, Kavadipula P, Bashyam MD.

    03/13/2021
    hsa-miR-100-5p, an overexpressed miRNA in human ovarian endometriotic stromal cells, promotes invasion through attenuation of SMARCD1 expression.

    hsa-miR-100-5p, an overexpressed miRNA in human ovarian endometriotic stromal cells, promotes invasion through attenuation of SMARCD1 expression.
    Takebayashi K, Nasu K, Okamoto M, Aoyagi Y, Hirakawa T, Narahara H., Free PMC Article

    02/6/2021
    BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation.

    BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation.
    Chang Z, Zhao G, Zhao Y, Lu H, Xiong W, Liang W, Sun J, Wang H, Zhu T, Rom O, Guo Y, Fan Y, Chang L, Yang B, Garcia-Barrio MT, Lin JD, Chen YE, Zhang J., Free PMC Article

    11/28/2020
    Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy.

    Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy.
    McGeachie MJ, Sordillo JE, Dahlin A, Wang AL, Lutz SM, Tantisira KG, Panganiban R, Lu Q, Sajuthi S, Urbanek C, Kelly R, Saef B, Eng C, Oh SS, Kho AT, Croteau-Chonka DC, Weiss ST, Raby BA, Mak ACY, Rodriguez-Santana JR, Burchard EG, Seibold MA, Wu AC., Free PMC Article

    10/24/2020
    Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues.

    Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues.
    Chow MZ, Sadrian SN, Keung W, Geng L, Ren L, Kong CW, Wong AO, Hulot JS, Chen CS, Costa KD, Hajjar RJ, Li RA., Free PMC Article

    10/24/2020
    Enhanced SMARCD1, a subunit of the SWI/SNF complex, promotes liver cancer growth through the mTOR pathway.

    Enhanced SMARCD1, a subunit of the SWI/SNF complex, promotes liver cancer growth through the mTOR pathway.
    Zhou Y, Xu Q, Tao L, Chen Y, Shu Y, Wu Z, Lu C, Shi Y, Bu H.

    10/10/2020
    MITF promoted BAF60A recruitment to melanocyte-specific promoters, and BAF60A was required to promote BRG1 recruitment and chromatin remodeling.

    BAF60A mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation.
    Aras S, Saladi SV, Basuroy T, Marathe HG, Lorès P, de la Serna IL., Free PMC Article

    05/9/2020
    identification of a human neurodevelopmental disorder caused by SMARCD1 mutations

    A Syndromic Neurodevelopmental Disorder Caused by Mutations in SMARCD1, a Core SWI/SNF Subunit Needed for Context-Dependent Neuronal Gene Regulation in Flies.
    Nixon KCJ, Rousseau J, Stone MH, Sarikahya M, Ehresmann S, Mizuno S, Matsumoto N, Miyake N, DDD Study, Baralle D, McKee S, Izumi K, Ritter AL, Heide S, Héron D, Depienne C, Titheradge H, Kramer JM, Campeau PM., Free PMC Article

    02/8/2020
    miR-223 targets the expression of SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinomas.

    miR-223 potentially targets SWI/SNF complex protein SMARCD1 in atypical proliferative serous tumor and high-grade ovarian serous carcinoma.
    Arts FA, Keogh L, Smyth P, O'Toole S, Ta R, Gleeson N, O'Leary JJ, Flavin R, Sheils O.

    10/20/2018
    BAF57, BAF60a and SNF5 might act as novel pro-senescence factors in both normal and tumor human skin cells

    Cellular senescence regulated by SWI/SNF complex subunits through p53/p21 and p16/pRB pathway.
    He L, Chen Y, Feng J, Sun W, Li S, Ou M, Tang L.

    11/18/2017
    the association of EGFR, CALM3 and SMARCD1 gene polymorphisms with bone mineral density in white women, as conducted.

    Comprehensive analysis of the association of EGFR, CALM3 and SMARCD1 gene polymorphisms with BMD in Caucasian women.
    Zhou QH, Zhao LJ, Wang P, Badr R, Xu XJ, Bu FX, Lappe J, Recker R, Zhou Y, Ye A, Zhou BT., Free PMC Article

    07/25/2015
    SMARCD1/BAF60a is an androgen receptor cofactor that modulates TMPRSS2 expression

    Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.
    van de Wijngaart DJ, Dubbink HJ, Molier M, de Vos C, Trapman J, Jenster G., Free PMC Article

    02/22/2010
    In addition to previously identified BAF250, BAF60a may provide another critical and direct link between nuclear receptors and the BRG1 complex that is required for promoter recruitment and subsequent chromatin remodeling

    BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.
    Hsiao PW, Fryer CJ, Trotter KW, Wang W, Archer TK., Free PMC Article

    01/21/2010
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