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    SNAI2 snail family transcriptional repressor 2 [ Homo sapiens (human) ]

    Gene ID: 6591, updated on 29-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cisplatin-resistant germ cell tumor models: An exploration of the epithelial-mesenchymal transition regulator SLUG.

    Cisplatin‑resistant germ cell tumor models: An exploration of the epithelial‑mesenchymal transition regulator SLUG.
    Cardoso IIV, Rosa MN, Moreno DA, Tufi LMB, Ramos LP, Pereira LAB, Silva L, Galvão JMS, Tosi IC, Lengert AVH, Da Cruz MC, Teixeira SA, Reis RM, Lopes LF, Pinto MT., Free PMC Article

    10/22/2024
    Homeobox B9 promotes the invasion and metastasis of hepatocellular carcinoma cells via the EZH2-MIR203A-SNAI2 axis.

    Homeobox B9 promotes the invasion and metastasis of hepatocellular carcinoma cells via the EZH2-MIR203A-SNAI2 axis.
    Zhang D, Qiu Y, Zhang W, Du D, Liu Y, Liu L, Li J, Chen Z, Yu X, Ye M, Wang W, Li Z, Shao J., Free PMC Article

    10/19/2024
    P4HA2 involved in SLUG-associated EMT predicts poor prognosis of patients with KRAS-positive colorectal cancer.

    P4HA2 involved in SLUG-associated EMT predicts poor prognosis of patients with KRAS-positive colorectal cancer.
    El-Deek HEM, El-Naggar MS, Morsy AMM, Sedik MF, Osman HA, Ahmed AM., Free PMC Article

    10/3/2024
    TGFbeta1, SNAIL2, and PAPP-A Expression in Placenta of Gestational Diabetes Mellitus Patients.

    TGFβ1, SNAIL2, and PAPP-A Expression in Placenta of Gestational Diabetes Mellitus Patients.
    He Y, Yang X, Wu N., Free PMC Article

    09/16/2024
    SNAI2/FTH1P3/miR-218-5p Positive Feedback Loop Promotes Colorectal Cancer Metastasis.

    SNAI2/FTH1P3/miR-218-5p Positive Feedback Loop Promotes Colorectal Cancer Metastasis.
    Deng H, Zhang Q, Zhao Z, Wang M, Xu Q.

    07/5/2024
    T-plastin contributes to epithelial-mesenchymal transition in human lung cancer cells through FAK/AKT/Slug axis signaling pathway.

    T-plastin contributes to epithelial-mesenchymal transition in human lung cancer cells through FAK/AKT/Slug axis signaling pathway.
    Park SY, Choi H, Choi SM, Wang S, Shim S, Jun W, Lee J, Chung JW., Free PMC Article

    07/5/2024
    The deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis.

    The deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis.
    Zhang R, Zhang D, Han F, Song X, Zhang Y, Zhang J, Zhu Q, Qin Y., Free PMC Article

    05/20/2024
    Downregulation of miR-95 in gastric cancer promotes EMT via regulation of Slug, thereby promoting migration and invasion.

    Downregulation of miR-95 in gastric cancer promotes EMT via regulation of Slug, thereby promoting migration and invasion.
    Zhang W, Sun J, Chen J, Xu C, Zhang L.

    02/21/2024
    Hsa_circ_0001707 regulates endothelial-mesenchymal transition in esophageal squamous cell carcinoma via miR-203a-3p/Snail2 pathway.

    Hsa_circ_0001707 regulates endothelial-mesenchymal transition in esophageal squamous cell carcinoma via miR-203a-3p/Snail2 pathway.
    Gao H, Sun M, Gao Z, Song J, Tang D, Liu R.

    02/8/2024
    SNAI2 promotes the malignant transformation of oral leukoplakia by modulating p-EMT.

    SNAI2 promotes the malignant transformation of oral leukoplakia by modulating p-EMT.
    Shang Q, Peng J, Jiang Y, Qing M, Zhou Y, Xu H, Chen Q.

    12/15/2023
    Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.

    Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.
    Vacondio D, Nogueira Pinto H, Coenen L, Mulder IA, Fontijn R, van Het Hof B, Fung WK, Jongejan A, Kooij G, Zelcer N, Rozemuller AJ, de Vries HE, de Wit NM., Free PMC Article

    12/1/2023
    A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma.

    A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma.
    Sreenivas P, Wang L, Wang M, Challa A, Modi P, Hensch NR, Gryder B, Chou HC, Zhao XR, Sunkel B, Moreno-Campos R, Khan J, Stanton BZ, Ignatius MS., Free PMC Article

    11/29/2023
    Specific intracellular retention of circSKA3 promotes colorectal cancer metastasis by attenuating ubiquitination and degradation of SLUG.

    Specific intracellular retention of circSKA3 promotes colorectal cancer metastasis by attenuating ubiquitination and degradation of SLUG.
    Deng J, Liao S, Chen C, Han F, Lei S, Lai X, Ye K, Han Q, E F, Lu C, Lai M, Liu F, Zhang H., Free PMC Article

    11/21/2023
    FSCN1 and epithelial mesenchymal transformation transcription factor expression in human pancreatic intraepithelial neoplasia and ductal adenocarcinoma.

    FSCN1 and epithelial mesenchymal transformation transcription factor expression in human pancreatic intraepithelial neoplasia and ductal adenocarcinoma.
    Morris HT, Bamlet WR, Razidlo GL, Machesky LM.

    11/18/2023
    ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression.

    ZNF451 favors triple-negative breast cancer progression by enhancing SLUG-mediated CCL5 transcriptional expression.
    Zhang Y, Wang W, Min J, Liu S, Wang Q, Wang Y, Xiao Y, Li X, Zhou Z, Liu S.

    10/16/2023
    PAK5 potentiates slug transactivation of N-cadherin to facilitate metastasis of renal cell carcinoma.

    PAK5 potentiates slug transactivation of N-cadherin to facilitate metastasis of renal cell carcinoma.
    Liu X, Pan YJ, Kang MJ, Jiang X, Guo ZY, Pei DS.

    09/6/2023
    A negative feedback loop between KLF9 and the EMT program dictates metastasis of hepatocellular carcinoma.

    A negative feedback loop between KLF9 and the EMT program dictates metastasis of hepatocellular carcinoma.
    Wang T, Feng L, Shi Z, Yang L, Yu X, Wu J, Sun J, Zhang J, Feng Y, Wang W., Free PMC Article

    08/19/2023
    Comprehensively prognostic and immunological analysis of snail family transcriptional repressor 2 in pan-cancer and identification in pancreatic carcinoma.

    Comprehensively prognostic and immunological analysis of snail family transcriptional repressor 2 in pan-cancer and identification in pancreatic carcinoma.
    Zhang D, Jiang Z, Hu J, Sun X, Zheng Y, Shen Y., Free PMC Article

    06/3/2023
    lncRNA AC005224.4/miR-140-3p/SNAI2 regulating axis facilitates the invasion and metastasis of ovarian cancer through epithelial-mesenchymal transition.

    lncRNA AC005224.4/miR-140-3p/SNAI2 regulating axis facilitates the invasion and metastasis of ovarian cancer through epithelial-mesenchymal transition.
    Xiong T, Wang Y, Zhang Y, Yuan J, Zhu C, Jiang W., Free PMC Article

    06/2/2023
    Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.

    Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.
    Zhang J, Hu Z, Chung HH, Tian Y, Lau KW, Ser Z, Lim YT, Sobota RM, Leong HF, Chen BJ, Yeo CJ, Tan SYX, Kang J, Tan DEK, Sou IF, McClurg UL, Lakshmanan M, Vaiyapuri TS, Raju A, Wong ESM, Tergaonkar V, Rajarethinam R, Pathak E, Tam WL, Tan EY, Tee WW., Free PMC Article

    05/3/2023
    SNAI2 Attenuated the Stem-like Phenotype by Reducing the Expansion of EPCAM[high] Cells in Cervical Cancer Cells.

    SNAI2 Attenuated the Stem-like Phenotype by Reducing the Expansion of EPCAM(high) Cells in Cervical Cancer Cells.
    Liu X, Zhang N, Chen Q, Feng Q, Zhang Y, Wang Z, Yue X, Li H, Cui N., Free PMC Article

    01/28/2023
    Sensitization to Ionizing Radiation by MEK Inhibition Is Dependent on SNAI2 in Fusion-Negative Rhabdomyosarcoma.

    Sensitization to Ionizing Radiation by MEK Inhibition Is Dependent on SNAI2 in Fusion-Negative Rhabdomyosarcoma.
    Hensch NR, Bondra K, Wang L, Sreenivas P, Zhao XR, Modi P, Vaseva AV, Houghton PJ, Ignatius MS., Free PMC Article

    01/11/2023
    CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug.

    CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug.
    Liang Y, Cen J, Huang Y, Fang Y, Wang Y, Shu G, Pan Y, Huang K, Dong J, Zhou M, Xu Y, Luo J, Liu M, Zhang J., Free PMC Article

    12/31/2022
    LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex.

    LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex.
    Li D, Shen L, Zhang X, Chen Z, Huang P, Huang C, Qin S., Free PMC Article

    12/10/2022
    LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug.

    LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug.
    Cutano V, Ferreira Mendes JM, Escudeiro-Lopes S, Machado S, Vinaixa Forner J, Gonzales-Morena JM, Prevorovsky M, Zemlianski V, Feng Y, Kralova Viziova P, Hartmanova A, Malcekova B, Jakoube P, Iyer S, Keckesova Z., Free PMC Article

    11/19/2022
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