| Nonsense suppression induces read-through of a novel BMPR1A variant in a Chinese family with hereditary colorectal cancer. | Nonsense suppression induces read-through of a novel BMPR1A variant in a Chinese family with hereditary colorectal cancer.
Wang Z, Shi J, Tao D, Xie S, Yang Y, Liu Y. | 09/1/2024 |
| ZEB1-AS1 mediates bone metastasis through targeting miR-320b/BMPR1A axis in lung cancer. | ZEB1-AS1 mediates bone metastasis through targeting miR-320b/BMPR1A axis in lung cancer.
Tan N, Tang J, Chen G, Jiang W, Liu Z., Free PMC Article | 06/11/2024 |
| Hsa-miR-27b-5p suppresses the osteogenic and odontogenic differentiation of stem cells from human exfoliated deciduous teeth via targeting BMPR1A: An ex vivo study. | Hsa-miR-27b-5p suppresses the osteogenic and odontogenic differentiation of stem cells from human exfoliated deciduous teeth via targeting BMPR1A: An ex vivo study.
Guo R, Gu T, Xiao Y, Xiao T, Liu Q, Li Z, Yu J. | 09/15/2023 |
| Adenomatous Polyposis Phenotype in BMPR1A and SMAD4 Variant Carriers. | Adenomatous Polyposis Phenotype in BMPR1A and SMAD4 Variant Carriers.
Rosner G, Petel-Galil Y, Laish I, Levi Z, Kariv R, Strul H, Gilad O, Gluck N., Free PMC Article | 11/5/2022 |
| Lysosomal protein transmembrane 5 promotes lung-specific metastasis by regulating BMPR1A lysosomal degradation. | Lysosomal protein transmembrane 5 promotes lung-specific metastasis by regulating BMPR1A lysosomal degradation.
Jiang B, Zhao X, Chen W, Diao W, Ding M, Qin H, Li B, Cao W, Chen W, Fu Y, He K, Gao J, Chen M, Lin T, Deng Y, Yan C, Guo H., Free PMC Article | 07/30/2022 |
| Bone morphogenetic protein receptor 1alpha promotes osteolytic lesion of oral squamous cell carcinoma by SHH-dependent osteoclastogenesis. | Bone morphogenetic protein receptor 1α promotes osteolytic lesion of oral squamous cell carcinoma by SHH-dependent osteoclastogenesis.
Qiao Q, Xu L, Li Q, Wang Y, Lu H, Zhao N, Pu Y, Wang L, Guo Y, Guo C., Free PMC Article | 05/28/2022 |
| BMP4/ALK3 deficiency leads to Meckel's cartilage truncation mimicking the mandible Tessier 30 cleft. | BMP4/ALK3 deficiency leads to Meckel's cartilage truncation mimicking the mandible Tessier 30 cleft.
Zhang J, Lin C, Song Y, Chen J. | 05/14/2022 |
| Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant. | Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant.
MacFarland SP, Ebrahimzadeh JE, Zelley K, Begum L, Bass LM, Brand RE, Dudley B, Fishman DS, Ganzak A, Karloski E, Latham A, Llor X, Plon S, Riordan MK, Scollon SR, Stadler ZK, Syngal S, Ukaegbu C, Weiss JM, Yurgelun MB, Brodeur GM, Mamula P, Katona BW., Free PMC Article | 04/30/2022 |
| Expression of GALNT8 and O-glycosylation of BMP receptor 1A suppress breast cancer cell proliferation by upregulating ERalpha levels. | Expression of GALNT8 and O-glycosylation of BMP receptor 1A suppress breast cancer cell proliferation by upregulating ERα levels.
Huang T, Wu Q, Huang H, Zhang C, Wang L, Wang L, Liu Y, Li W, Zhang J, Liu Y. | 01/15/2022 |
| Anti-Mullerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survival. | Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survival.
Chauvin M, Garambois V, Choblet S, Colombo PE, Chentouf M, Gros L, De Brauwere DP, Duonor-Cerutti M, Dumas K, Robert B, Jarlier M, Martineau P, Navarro-Teulon I, Pépin D, Chardès T, Pèlegrin A., Free PMC Article | 12/11/2021 |
| Bone morphogenetic protein signaling regulates skin inflammation via modulating dendritic cell function. | Bone morphogenetic protein signaling regulates skin inflammation via modulating dendritic cell function.
Sconocchia T, Hochgerner M, Schwarzenberger E, Tam-Amersdorfer C, Borek I, Benezeder T, Bauer T, Zyulina V, Painsi C, Passegger C, Wolf P, Sibilia M, Strobl H. | 09/25/2021 |
| BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation. | BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation.
Mang T, Kleinschmidt-Doerr K, Ploeger F, Schoenemann A, Lindemann S, Gigout A. | 07/3/2021 |
| Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant carriers. | Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant carriers.
Blatter R, Tschupp B, Aretz S, Bernstein I, Colas C, Evans DG, Genuardi M, Hes FJ, Hüneburg R, Järvinen H, Lalloo F, Moeslein G, Renkonen-Sinisalo L, Resta N, Spier I, Varvara D, Vasen H, Latchford AR, Heinimann K., Free PMC Article | 05/8/2021 |
| BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency. | BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency.
Renault L, Patiño LC, Magnin F, Delemer B, Young J, Laissue P, Binart N, Beau I. | 01/9/2021 |
| Variable Features of Juvenile Polyposis Syndrome With Gastric Involvement Among Patients With a Large Genomic Deletion of BMPR1A. | Variable Features of Juvenile Polyposis Syndrome With Gastric Involvement Among Patients With a Large Genomic Deletion of BMPR1A.
Lieberman S, Beeri R, Walsh T, Schechter M, Keret D, Half E, Gulsuner S, Tomer A, Jacob H, Cohen S, Basel-Salmon L, Mansur M, Berger R, Katz LH, Golomb E, Peretz T, Levy Z, Kedar I, King MC, Levy-Lahad E, Goldberg Y., Free PMC Article | 09/5/2020 |
| dentified an interstitial 10q23.1q23.3 deletion in a buccal mucosa sample of Patient 1 that encompassed PTEN, BMPR1A, and KLLN, among others. In contrast, neither sequencing nor array-CGH analysis identified a pathogenic variant in PTEN or BMPR1A in a blood sample of Patient 2 | Looking for the hidden mutation: Bannayan-Riley-Ruvalcaba syndrome caused by constitutional and mosaic 10q23 microdeletions involving PTEN and BMPR1A.
Golas MM, Auber B, Ripperger T, Pabst B, Schmidt G, Morlot M, Diebold U, Steinemann D, Schlegelberger B, Morlot S. | 07/11/2020 |
| This high expression of BMPR1A is further increased upon BMP4 exposure. | A new signaling cascade linking BMP4, BMPR1A, ΔNp73 and NANOG impacts on stem-like human cell properties and patient outcome.
Voeltzel T, Flores-Violante M, Zylbersztejn F, Lefort S, Billandon M, Jeanpierre S, Joly S, Fossard G, Milenkov M, Mazurier F, Nehme A, Belhabri A, Paubelle E, Thomas X, Michallet M, Louache F, Nicolini FE, Caron de Fromentel C, Maguer-Satta V., Free PMC Article | 11/16/2019 |
| IL-6 may be responsible for coformation of new bone and excessive adipose tissue in rhBMP-2-induced bone voids. | IL-6 potentiates BMP-2-induced osteogenesis and adipogenesis via two different BMPR1A-mediated pathways.
Huang RL, Sun Y, Ho CK, Liu K, Tang QQ, Xie Y, Li Q., Free PMC Article | 08/3/2019 |
| Study findings highlight that BMPR1a mutations are not a major contributor of Familial colorectal cancer type X incidence in Newfoundland. | Screening of BMPR1a for pathogenic mutations in familial colorectal cancer type X families from Newfoundland.
Evans DR, Green JS, Woods MO. | 02/2/2019 |
| Single nucleotide polymorphisms of the BMPR-1A gene were significantly associated with the development of ossification of the posterior longitudinal ligament of the cervical spine. | Genetic polymorphisms in bone morphogenetic protein receptor type IA gene predisposes individuals to ossification of the posterior longitudinal ligament of the cervical spine via the smad signaling pathway.
Wang H, Jin W, Li H., Free PMC Article | 09/1/2018 |
| The binding free energies indicate that ALK-3 preferably binds to BMP-2 instead of BMP-9. The structural analysis shows that ALK-3 binding with BMP-2 occurs in a perfectly symmetry pathway, whereas this symmetry is lost for possible ALK-3 interactions with BMP-9 | BMP-2 and BMP-9 binding specificities with ALK-3 in aqueous solution with dynamics.
Coskuner O, Uversky VN. | 07/28/2018 |
| BMPR1A mutation in superior coloboma | Morphogenetic defects underlie Superior Coloboma, a newly identified closure disorder of the dorsal eye.
Hocking JC, Famulski JK, Yoon KH, Widen SA, Bernstein CS, Koch S, Weiss O, FORGE Canada Consortium, Agarwala S, Inbal A, Lehmann OJ, Waskiewicz AJ., Free PMC Article | 07/14/2018 |
| Knockdown of BMPR1a of breast cancer cells suppresses their production of RANKL via p38 pathway and inhibits cancer-induced osteoclastogenesis. | Knockdown of Bone Morphogenetic Proteins Type 1a Receptor (BMPR1a) in Breast Cancer Cells Protects Bone from Breast Cancer-Induced Osteolysis by Suppressing RANKL Expression.
Liu Y, Zhang RX, Yuan W, Chen HQ, Tian DD, Li H, Jiang X, Deng ZL, Wang Y. | 05/19/2018 |
| both bone morphogenetic protein 2 (BMP2) and BMP6 are proangiogenic in vitro and ex vivo and that the BMP type I receptors, activin receptor-like kinase 3 (ALK3) and ALK2, play crucial and distinct roles in this process. | Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence.
Benn A, Hiepen C, Osterland M, Schütte C, Zwijsen A, Knaus P., Free PMC Article | 11/25/2017 |
| BMPR1A and the ubiquitous isoform of BMPR1B differed in mode of translocation into the endoplasmic reticulum; and (ii) BMPR1A was N-glycosylated while BMPR1B was not, resulting in greater efficiency of processing and plasma membrane expression of BMPR1A. | Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.
Hirschhorn T, Levi-Hofman M, Danziger O, Smorodinsky NI, Ehrlich M., Free PMC Article | 09/2/2017 |