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    SLC16A1 solute carrier family 16 member 1 [ Homo sapiens (human) ]

    Gene ID: 6566, updated on 7-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Oncogenic circ-SLC16A1 promotes progression of non-small cell lung cancer via regulation of the miR-1287-5p/profilin 2 axis.

    Oncogenic circ-SLC16A1 promotes progression of non-small cell lung cancer via regulation of the miR-1287-5p/profilin 2 axis.
    Jin M, Yuan T, Tian K, Li J, Huang Q, Chi Y, Huang G., Free PMC Article

    04/1/2024
    To initiate or not to initiate: A critical assessment of eIF2A, eIF2D, and MCT-1.DENR to deliver initiator tRNA to ribosomes.

    To initiate or not to initiate: A critical assessment of eIF2A, eIF2D, and MCT-1·DENR to deliver initiator tRNA to ribosomes.
    Grove DJ, Russell PJ, Kearse MG.

    03/5/2024
    MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.

    MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation.
    Chi W, Kang N, Sheng L, Liu S, Tao L, Cao X, Liu Y, Zhu C, Zhang Y, Wu B, Chen R, Cheng L, Wang J, Sun X, Liu X, Deng H, Yang J, Li Z, Liu W, Chen L., Free PMC Article

    01/9/2024
    Role of monocarboxylate transporter I/lactate dehydrogenase B-mediated lactate recycling in tamoxifen-resistant breast cancer cells.

    Role of monocarboxylate transporter I/lactate dehydrogenase B-mediated lactate recycling in tamoxifen-resistant breast cancer cells.
    Choi MC, Kim SK, Choi YJ, Choi YJ, Kim S, Jegal KH, Lim SC, Kang KW.

    12/26/2023
    SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle.

    SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle.
    She X, Wu Q, Rao Z, Song D, Huang C, Feng S, Liu A, Liu L, Wan K, Li X, Yu C, Qiu C, Luo X, Hu J, Wang G, Xu F, Sun L., Free PMC Article

    10/10/2023
    Comprehensive analysis of pan-cancer reveals the potential of SLC16A1 as a prognostic and immunological biomarker.

    Comprehensive analysis of pan-cancer reveals the potential of SLC16A1 as a prognostic and immunological biomarker.
    Chen L, Li Y, Deng X., Free PMC Article

    04/19/2023
    Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review.

    Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review.
    Silva A, Cerqueira MC, Rosa B, Sobral C, Pinto-Ribeiro F, Costa MF, Baltazar F, Afonso J., Free PMC Article

    03/30/2023
    Immunohistochemical evaluation and prognostic value of monocarboxylate transporter 1 (MCT1) and 4 (MCT4) in T-cell non-Hodgkin lymphoma.

    Immunohistochemical evaluation and prognostic value of monocarboxylate transporter 1 (MCT1) and 4 (MCT4) in T-cell non-Hodgkin lymphoma.
    Zhao H, Chen Y, Liao YP, Chen HM, Yang QH, Xiao Y, Luo J, Chen ZZ, Yi L, Hu GY.

    02/27/2023
    Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis.

    Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis.
    Sheng G, Gao Y, Wu H, Liu Y, Yang Y., Free PMC Article

    02/24/2023
    Involvement of SLC16A1/MCT1 and SLC16A3/MCT4 in l-lactate transport in the hepatocellular carcinoma cell line.

    Involvement of SLC16A1/MCT1 and SLC16A3/MCT4 in l-lactate transport in the hepatocellular carcinoma cell line.
    Mukai Y, Yamaguchi A, Sakuma T, Nadai T, Furugen A, Narumi K, Kobayashi M.

    01/28/2023
    Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10.

    Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10.
    Ohtsu N, Ohgaki R, Jin C, Xu M, Okanishi H, Takahashi R, Matsui A, Kishimoto W, Ishiguro N, Kanai Y.

    08/13/2022
    Transmission Distortion of MCT1 rs1049434 among Polish Elite Athletes.

    Transmission Distortion of MCT1 rs1049434 among Polish Elite Athletes.
    Dzitkowska-Zabielska M, Bojarczuk A, Borczyk M, Piechota M, Korostyński M, Adamczyk JG, Trybek G, Massidda M, Cięszczyk P., Free PMC Article

    06/11/2022
    A Novel Metabolic Reprogramming Strategy for the Treatment of Diabetes-Associated Breast Cancer.

    A Novel Metabolic Reprogramming Strategy for the Treatment of Diabetes-Associated Breast Cancer.
    Hao Q, Huang Z, Li Q, Liu D, Wang P, Wang K, Li J, Cao W, Deng W, Wu K, Su R, Liu Z, Vadgama J, Wu Y., Free PMC Article

    03/26/2022
    Influence of the MCT1-T1470A polymorphism (rs1049434) on repeated sprint ability and blood lactate accumulation in elite football players: a pilot study.

    Influence of the MCT1-T1470A polymorphism (rs1049434) on repeated sprint ability and blood lactate accumulation in elite football players: a pilot study.
    Massidda M, Flore L, Kikuchi N, Scorcu M, Piras F, Cugia P, Cięszczyk P, Tocco F, Calò CM.

    02/19/2022
    Coexpression of MCT1 and MCT4 in ALK-positive Anaplastic Large Cell Lymphoma: Diagnostic and Therapeutic Implications.

    Coexpression of MCT1 and MCT4 in ALK-positive Anaplastic Large Cell Lymphoma: Diagnostic and Therapeutic Implications.
    Choi JW, Lee Y, Kim H, Cho HY, Min SK, Kim YS.

    02/19/2022
    Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition.

    Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition.
    Vander Linden C, Corbet C, Bastien E, Martherus R, Guilbaud C, Petit L, Wauthier L, Loriot A, De Smet C, Feron O.

    02/12/2022
    Overexpression of Cell-Surface Marker SLC16A1 Shortened Survival in Human High-Grade Gliomas.

    Overexpression of Cell-Surface Marker SLC16A1 Shortened Survival in Human High-Grade Gliomas.
    Lin HH, Tsai WC, Tsai CK, Chen SH, Huang LC, Hueng DY, Hung KC.

    01/8/2022
    Monocarboxylate transporter-1 (MCT1) protein expression in head and neck cancer affects clinical outcome.

    Monocarboxylate transporter-1 (MCT1) protein expression in head and neck cancer affects clinical outcome.
    Leu M, Kitz J, Pilavakis Y, Hakroush S, Wolff HA, Canis M, Rieken S, Schirmer MA., Free PMC Article

    12/25/2021
    miR-31-NUMB Cascade Modulates Monocarboxylate Transporters to Increase Oncogenicity and Lactate Production of Oral Carcinoma Cells.

    miR-31-NUMB Cascade Modulates Monocarboxylate Transporters to Increase Oncogenicity and Lactate Production of Oral Carcinoma Cells.
    Chou CH, Chiang CF, Yang CC, Liu YC, Chang SR, Chang KW, Lin SC., Free PMC Article

    12/18/2021
    Monocarboxylate transporter 1 promotes proliferation and invasion of renal cancer cells by mediating acetate transport.

    Monocarboxylate transporter 1 promotes proliferation and invasion of renal cancer cells by mediating acetate transport.
    Li M, Long X, Wan H, Yin M, Yang B, Zhang F, Guo X.

    11/27/2021
    Excess exogenous pyruvate inhibits lactate dehydrogenase activity in live cells in an MCT1-dependent manner.

    Excess exogenous pyruvate inhibits lactate dehydrogenase activity in live cells in an MCT1-dependent manner.
    Rao Y, Gammon ST, Sutton MN, Zacharias NM, Bhattacharya P, Piwnica-Worms D., Free PMC Article

    08/28/2021
    Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report).

    Tissue expression of lactate transporters (MCT1 and MCT4) and prognosis of malignant pleural mesothelioma (brief report).
    Dell'Anno I, Barone E, Mutti L, Rassl DM, Marciniak SJ, Silvestri R, Landi S, Gemignani F., Free PMC Article

    07/10/2021
    LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1.

    LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1.
    Logotheti S, Marquardt S, Gupta SK, Richter C, Edelhäuser BAH, Engelmann D, Brenmoehl J, Söhnchen C, Murr N, Alpers M, Singh KP, Wolkenhauer O, Heckl D, Spitschak A, Pützer BM., Free PMC Article

    05/29/2021
    Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1.

    Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1.
    Granlund KL, Tee SS, Vargas HA, Lyashchenko SK, Reznik E, Fine S, Laudone V, Eastham JA, Touijer KA, Reuter VE, Gonen M, Sosa RE, Nicholson D, Guo YW, Chen AP, Tropp J, Robb F, Hricak H, Keshari KR., Free PMC Article

    05/15/2021
    Delayed Myelination Pattern and an Abnormal Thyroid Profile Caused by a Novel Mutation in the SLC16A2 Gene.

    Delayed Myelination Pattern and an Abnormal Thyroid Profile Caused by a Novel Mutation in the SLC16A2 Gene.
    Sharawat IK, Suthar R, Saini AG, Vyas S.

    05/8/2021
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