SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment. | SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment. Wu D, Zhou Y, Shi X, Yi X, Sheng Z, Fan L, Ge J, Cheng W, Zhou W, He H, Fu D. | 06/13/2024 |
Systemic assessment of solute carrier family 11-member A1 (rs17235409) gene polymorphism and Mycobacterium Tuberculosis Risk in Asian and caucasian population: A comprehensive updated meta-analysis. | Systemic assessment of solute carrier family 11-member A1 (rs17235409) gene polymorphism and Mycobacterium Tuberculosis Risk in Asian and caucasian population: A comprehensive updated meta-analysis. Pauline R, Devaraj DV, Sivasubramanian J, Velmurugan S, Stephen SB, Yasam SK, Kulanthaivel L, Subbaraj GK. | 12/28/2023 |
The expression of Nramp1 modulates the uptake of Mycobacterium tuberculosis by macrophages through alternating inflammatory responses. | The expression of Nramp1 modulates the uptake of Mycobacterium tuberculosis by macrophages through alternating inflammatory responses. Meng C, Chen G, Wen D, Dong L, Cui X, Jing X, Cui J, Gao Y, Liu Y, Bu H, Wu C. | 12/6/2023 |
Serum iron levels in tuberculosis patients and household contacts and its association with natural resistance-associated macrophage protein 1 polymorphism and expression. | Serum iron levels in tuberculosis patients and household contacts and its association with natural resistance-associated macrophage protein 1 polymorphism and expression. Waworuntu W, Tanoerahardjo FS, Mallongi A, Ahmad A, Amin M, Djaharuddin I, Bukhari A, Tabri NA, Bahar B, Hidayah N, Halik H, Massi MN., Free PMC Article | 09/18/2023 |
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1. | USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1. Duan J, Huang D, Liu C, Lv Y, Zhang L, Chang F, Zeng X, Li L, Wang W, Shao G., Free PMC Article | 07/12/2023 |
Solute carrier family 11 member 1 genetic polymorphisms rs17235409 and rs3731865 associate with susceptibility to extremity post-traumatic osteomyelitis in a Chinese Han population. | Solute carrier family 11 member 1 genetic polymorphisms rs17235409 and rs3731865 associate with susceptibility to extremity post-traumatic osteomyelitis in a Chinese Han population. Jiang N, Zhong YC, Lin QR, Song CS, Yu B, Hu YJ. | 05/17/2023 |
Association of SLC11A1 polymorphisms with anthropometric and biochemical parameters describing Type 2 Diabetes Mellitus. | Association of SLC11A1 polymorphisms with anthropometric and biochemical parameters describing Type 2 Diabetes Mellitus. Kavian Z, Sargazi S, Majidpour M, Sarhadi M, Saravani R, Shahraki M, Mirinejad S, Heidari Nia M, Piri M., Free PMC Article | 04/19/2023 |
SLC11A1 genetic variation and low expression may cause immune response impairment in TB patients. | SLC11A1 genetic variation and low expression may cause immune response impairment in TB patients. Shahzad F, Bashir N, Ali A, Nadeem A, Ammar A, Kashif M, Javaid K, Jahan S, Tahir R, Rizwan M, Mushtaq A, Afzal N. | 07/30/2022 |
Polymorphisms of SLC11A1(NRAMP1) rs17235409 associated with and susceptibility to spinal tuberculosis in a southern Han Chinese population. | Polymorphisms of SLC11A1(NRAMP1) rs17235409 associated with and susceptibility to spinal tuberculosis in a southern Han Chinese population. Li T, Wang L, Guo C, Zhang H, Xu P, Liu S, Hu X, Gao Q. | 05/21/2022 |
Mutation analysis of seven SLC family transporters for early-onset Parkinson's disease in Chinese population. | Mutation analysis of seven SLC family transporters for early-onset Parkinson's disease in Chinese population. Li C, Ou R, Chen Y, Gu X, Wei Q, Cao B, Zhang L, Hou Y, Liu K, Chen X, Song W, Zhao B, Wu Y, Shang H. | 12/25/2021 |
Association of genetic variants in autophagy-lysosome pathway genes with susceptibility and survival to prostate cancer. | Association of genetic variants in autophagy-lysosome pathway genes with susceptibility and survival to prostate cancer. Zhu Q, Meng Y, Li S, Xin J, Du M, Wang M, Cheng G. | 12/4/2021 |
LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2. | LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2. Ni K, Muegge K., Free PMC Article | 10/9/2021 |
The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation. | The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation. Xu X, Ni K, He Y, Ren J, Sun C, Liu Y, Aladjem MI, Burkett S, Finney R, Ding X, Sharan SK, Muegge K., Free PMC Article | 07/3/2021 |
The polymorphism of the SLC11A1 gene (rs3731865) was associated with visceral leishmaniasis-HIV coinfection, suggesting a possible genetic mechanism involved in the susceptibility to visceral leishmaniasis in HIV patients. | SLC11A1 (rs3731865) polymorphism and susceptibility to visceral leishmaniasis in HIV-coinfected patients from Northeastern Brazil. Barbosa Júnior WL, Justo AM, Dos Santos AMA, do Carmo RF, de Melo FL, Vasconcelos LRS, de Medeiros ZM. | 04/11/2020 |
expressed in the syncytiotrophoblast of the placenta at multiple gestational ages | SLC11A1 is expressed in the human placenta across multiple gestational ages. Perry ID, Krishnan L, Murphy SP. | 03/21/2020 |
TT genotype (OR=0.338, 95%CI=0.278-1.214, P=0.028) and T allele (OR=0.608, 95%CI=0.298-0.956, P=0.005) showed close association with reduced risk of rheumatoid arthritis (RA). For rs1059823, no obvious diversity was uncovered in either genotype or allele distribution between the 2 groups. Interaction analysis showed that smoking decreased the protective function of TT in rs17221959. | Correlation of Polymorphisms of Natural Resistance-Associated Macrophage Protein 1 (NRAMP1) Gene and Smoking with the Risk of Rheumatoid Arthritis in Chinese Han People. Zou Q, Zhao Y, Wang Y, Fang Y, Liu Y., Free PMC Article | 02/15/2020 |
These findings indicate a critical role for LSH as a biomarker and therapeutic target in follicular germinal center B-cell lymphoma. | Chromatin remodeling factor lymphoid-specific helicase links with Epstein-Barr virus associated the follicular germinal center B cell lymphomas. Ouyang C, Deng Z, Zhou J, Fu C, Liu S, Tao Y, Xiao D. | 08/3/2019 |
the association between natural resistance-associated macrophage protein 1 (NRAMP1) polymorphisms and rheumatoid arthritis (Meta-Analysis) | Association between rheumatoid arthritis and genetic variants of natural resistance-associated macrophage protein 1 gene: A meta-analysis. Wang H, Yuan FF, Dai ZW, Wang B, Ye DQ. | 05/4/2019 |
important roles for c-Src tyrosine kinase in phosphorylation and activation of SLC11A1 in macrophages | c-Src kinase is involved in the tyrosine phosphorylation and activity of SLC11A1 in differentiating macrophages. Xu YZ, Thuraisingam T, Kanagaratham C, Tao S, Radzioch D., Free PMC Article | 08/4/2018 |
3'UTR-NRAMP1 gene and VDR-Taq1 gene Polymorphisms are statistically associated with the susceptibility of TB in Andhra Pradesh Population in India. | NRAMP1 and VDR gene polymorphisms in susceptibility to pulmonary tuberculosis among Andhra Pradesh population in India: a case-control study. Medapati RV, Suvvari S, Godi S, Gangisetti P., Free PMC Article | 06/2/2018 |
Nramp1 is expressed in microglia and neurons in the striatum of human brain and response for degrading alpha-synuclein oligomers in microglia. | The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload condition. Wu KC, Liou HH, Kao YH, Lee CY, Lin CJ. | 03/24/2018 |
This study identified several important polymorphisms in the ITPKC and SLC11A1 genes in Koreans. | ITPKC and SLC11A1 Gene Polymorphisms and Gene-Gene Interactions in Korean Patients with Kawasaki Disease. Kim KY, Bae YS, Ji W, Shin D, Kim HS, Kim DS., Free PMC Article | 03/10/2018 |
Studied the role of natural resistance associated macrophage protein 1 (NRAMP1) polymorphisms (D543N, INT4) in pulmonary tuberculosis risk. For D543NA/G polymorphism, no associations were found in all genetic models. For INT4C/G polymorphism, significant increased PTB risk was observed in recessive model. | NRAMP1 D543N and INT4 polymorphisms in susceptibility to pulmonary tuberculosis: A meta-analysis. Yuan L, Ke Z, Guo Y, Xi X, Luo Z. | 02/3/2018 |
This study shows that genetic variations in the candidate gene SLC11A1 do not affect susceptibility to cutaneous leishmaniasis in the sample population from Pakistan. | SLC11A1 polymorphisms and host susceptibility to cutaneous leishmaniasis in Pakistan. Sophie M, Hameed A, Muneer A, Samdani AJ, Saleem S, Azhar A., Free PMC Article | 01/13/2018 |
in patients with non-muscle-invasive bladder cancer, the NRAMP1 D534N polymorphism could increase the risk of recurrence | [The relationship between tumor recurrence and polymorphisms of hGPX1 and NRAMP1 in superficial bladder cancer patients: a meta-analysis]. Souraka TDM, Shi MJ, Meng XY., Free PMC Article | 12/9/2017 |