| Potential prognostic and therapeutic value of ANXA8 in renal cell carcinoma: based on the comprehensive analysis of annexins family. | Potential prognostic and therapeutic value of ANXA8 in renal cell carcinoma: based on the comprehensive analysis of annexins family.
Wang LH, Cao B, Li YL, Qiao BP., Free PMC Article | 07/25/2023 |
| [ANXA8 Regulates Proliferation of Human Non-Small Lung Cancer Cells A549 via EGFR-AKT-mTOR Signaling Pathway]. | [ANXA8 Regulates Proliferation of Human Non-Small Lung Cancer Cells A549 via EGFR-AKT-mTOR Signaling Pathway].
Zhou GZ, Sun YH, Shi YY, Zhang Q, Zhang L, Cui LQ, Sun GC. | 10/30/2021 |
| ANXA8 was significantly highly expressed in ovarian cancer, and high ANXA8 expression was significantly correlated with poor prognosis. | Annexin A8 can serve as potential prognostic biomarker and therapeutic target for ovarian cancer: based on the comprehensive analysis of Annexins.
Gou R, Zhu L, Zheng M, Guo Q, Hu Y, Li X, Liu J, Lin B., Free PMC Article | 07/18/2020 |
| Data show that down-regulation of AnxA8 is both necessary and sufficient for neuronal trans-differentiation of retinal pigment epithelial (RPE) cells and reveal an essential role for AnxA8 as a key regulator of RPE phenotype. | Regulation of retinal pigment epithelial cell phenotype by Annexin A8.
Lueck K, Carr AF, Stampoulis D, Gerke V, Rescher U, Greenwood J, Moss SE., Free PMC Article | 02/2/2019 |
| These findings identify Anxa8 as a regulator of late endosomes/lysosomes cholesterol balance. | Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.
Heitzig N, Kühnl A, Grill D, Ludewig K, Schloer S, Galla HJ, Grewal T, Gerke V, Rescher U. | 06/2/2018 |
| We conclude that AnxA8 affects CD63/VEGFR2/beta1 integrin complex formation, leading to hyperactivation of the VEGF-A signal transduction pathway, and severely disturbed VEGF-A-driven angiogenic sprouting. | Annexin A8 promotes VEGF-A driven endothelial cell sprouting.
Heitzig N, Brinkmann BF, Koerdt SN, Rosso G, Shahin V, Rescher U., Free PMC Article | 03/17/2018 |
| Annexins A2 and A8 in endothelial cell exocytosis and the control of vascular homeostasis | Annexins A2 and A8 in endothelial cell exocytosis and the control of vascular homeostasis.
Gerke V. | 06/24/2017 |
| Increased annexin A8 expression is associated with poor prognosis in early-stage pancreatic cancer. | Annexin A8 Is a Prognostic Marker and Potential Therapeutic Target for Pancreatic Cancer.
Pimiento JM, Chen DT, Centeno BA, Davis-Yadley AH, Husain K, Fulp WJ, Wang C, Zhang A, Malafa MP., Free PMC Article | 11/12/2016 |
| High ANXA8 gene expression is associated with lymph node metastasis in oral squamous cell carcinoma. | Annexin A8 is a novel molecular marker for detecting lymph node metastasis in oral squamous cell carcinoma.
Oka R, Nakashiro K, Goda H, Iwamoto K, Tokuzen N, Hamakawa H., Free PMC Article | 11/5/2016 |
| Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63. | Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.
Poeter M, Brandherm I, Rossaint J, Rosso G, Shahin V, Skryabin BV, Zarbock A, Gerke V, Rescher U. | 12/20/2014 |
| High ANXA8 expression is associated with pancreatic cancer. | Involvement of annexin A8 in the properties of pancreatic cancer.
Hata H, Tatemichi M, Nakadate T. | 04/26/2014 |
| Define a distinct bone-dependent genetic program associated with terminal osteoclast differentiation and identified Anxa8 as a gene strongly induced late in osteoclast differentiation, regulating formation of the cell's characteristic actin ring. | Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.
Crotti TN, O'Sullivan RP, Shen Z, Flannery MR, Fajardo RJ, Ross FP, Goldring SR, McHugh KP. | 11/19/2011 |
| Data suggest that defective transport through the late endocytic pathway and imbalanced signaling in the absence of annexin A8 results from disturbed association of late endosomal membranes with actin and impaired endosome motility. | Annexin A8 regulates late endosome organization and function.
Goebeler V, Poeter M, Zeuschner D, Gerke V, Rescher U., Free PMC Article | 01/21/2010 |
| Annexin A8 is involved in mouse mammary gland involution and progression of human breast cancer | Annexin A8 is up-regulated during mouse mammary gland involution and predicts poor survival in breast cancer.
Stein T, Price KN, Morris JS, Heath VJ, Ferrier RK, Bell AK, Pringle MA, Villadsen R, Petersen OW, Sauter G, Bryson G, Mallon EA, Gusterson BA. | 01/21/2010 |
| binds Ca2+-dependently and with high specificity to phosphatidylinositol (4,5)-bisphosphate (PtdIns(4,5)P2) and is also capable of interacting with F-actin | Annexin A8 displays unique phospholipid and F-actin binding properties.
Goebeler V, Ruhe D, Gerke V, Rescher U. | 01/21/2010 |