Deciphering the neuroprotective mechanisms of RACK1 in cerebral ischemia-reperfusion injury: Pioneering insights into mitochondrial autophagy and the PINK1/Parkin axis. | Deciphering the neuroprotective mechanisms of RACK1 in cerebral ischemia-reperfusion injury: Pioneering insights into mitochondrial autophagy and the PINK1/Parkin axis. Zhao L, Chen Y, Li H, Ding X, Li J., Free PMC Article | 08/7/2024 |
Sgt1 Regulates alpha-Synuclein Subcellular Localization and Expression of Parkinson's Disease Related Genes, PINK1 and PARK9. | Sgt1 Regulates α-Synuclein Subcellular Localization and Expression of Parkinson's Disease Related Genes, PINK1 and PARK9. Bohush A, Góral A, Sierant M, Nawrot B, Leśniak W, Filipek A., Free PMC Article | 07/29/2024 |
PINK1/Park2-Mediated Mitophagy Relieve Non-Alcoholic Fatty Liver Disease. | PINK1/Park2-Mediated Mitophagy Relieve Non-Alcoholic Fatty Liver Disease. He H, Tang Y, Zhuang L, Zheng Y, Huang X., Free PMC Article | 06/1/2024 |
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy. | Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy. Ji H, Zhao Y, Ma X, Wu L, Guo F, Huang F, Song Y, Wang J, Qin G. | 05/31/2024 |
The SCF-FBW7beta E3 ligase mediates ubiquitination and degradation of the serine/threonine protein kinase PINK1. | The SCF-FBW7β E3 ligase mediates ubiquitination and degradation of the serine/threonine protein kinase PINK1. Jeon SJ, Chung KC., Free PMC Article | 05/24/2024 |
PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway. | PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway. Zheng F, Zhong J, Chen K, Shi Y, Wang F, Wang S, Tang S, Yuan X, Shen Z, Tang S, Xia D, Wu Y, Lu W., Free PMC Article | 03/15/2024 |
METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy. | METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy. Wang F, Bai J, Zhang X, Wang D, Zhang X, Xue J, Chen H, Wang S, Chi B, Li J, Ma X., Free PMC Article | 03/13/2024 |
PINK1 dominated mitochondria associated genes signature predicts abdominal aortic aneurysm with metabolic syndrome. | PINK1 dominated mitochondria associated genes signature predicts abdominal aortic aneurysm with metabolic syndrome. Wang K, Zhou Z, Huang L, Kan Q, Wang Z, Wu W, Yao C. | 02/16/2024 |
PINK1-mediated mitophagy reduced inflammatory responses to Porphyromonas gingivalis in macrophages. | PINK1-mediated mitophagy reduced inflammatory responses to Porphyromonas gingivalis in macrophages. Jiang K, Li J, Jiang L, Li H, Lei L. | 01/30/2024 |
[Interaction of SENP6 with PINK1 Promotes Temozolomide Resistance in Neuroglioma Cells via Inducing the Mitophagy]. | [Interaction of SENP6 with PINK1 Promotes Temozolomide Resistance in Neuroglioma Cells via Inducing the Mitophagy]. Wang YW, Jia KG, Xing HJ, Pan Y, Zeng CS, Chen L, Su QJ, Shen WT, Chen J, Chen C, Cao Q, Wang YY. | 01/5/2024 |
Role of Pink1-mediated mitophagy in adenomyosis. | Role of Pink1-mediated mitophagy in adenomyosis. Chen M, Wang W, Fu X, Yi Y, Wang K, Wang M., Free PMC Article | 12/6/2023 |
Mitochondria-Endoplasmic Reticulum Contact Sites Dynamics and Calcium Homeostasis Are Differentially Disrupted in PINK1-PD or PRKN-PD Neurons. | Mitochondria-Endoplasmic Reticulum Contact Sites Dynamics and Calcium Homeostasis Are Differentially Disrupted in PINK1-PD or PRKN-PD Neurons. Grossmann D, Malburg N, Glaß H, Weeren V, Sondermann V, Pfeiffer JF, Petters J, Lukas J, Seibler P, Klein C, Grünewald A, Hermann A. | 11/1/2023 |
AI molecular property prediction for Parkinson's Disease reveals potential repurposing drug candidates based on the increase of the expression of PINK1. | AI molecular property prediction for Parkinson's Disease reveals potential repurposing drug candidates based on the increase of the expression of PINK1. Haneczok J, Delijewski M, Moldzio R. | 09/11/2023 |
Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent. | Alpha-synuclein-associated changes in PINK1-PRKN-mediated mitophagy are disease context dependent. Hou X, Chen TH, Koga S, Bredenberg JM, Faroqi AH, Delenclos M, Bu G, Wszolek ZK, Carr JA, Ross OA, McLean PJ, Murray ME, Dickson DW, Fiesel FC, Springer W., Free PMC Article | 08/31/2023 |
PINK1 and oxidative stress in lean and obese patients with type 2 diabetes mellitus. | PINK1 and oxidative stress in lean and obese patients with type 2 diabetes mellitus. Almeida EA, Mehndiratta M, Madhu SV, Kar R, Puri D. | 08/4/2023 |
Intrafamilial and interfamilial heterogeneity of PINK1-associated Parkinson's disease in Sudan. | Intrafamilial and interfamilial heterogeneity of PINK1-associated Parkinson's disease in Sudan. Bakhit Y, Ibrahim MO, Tesson C, Elhassan AA, Ahmed MA, Alebeed MA, Elrasheed SM, Omar MA, Abubaker R, Eltom K, Shaheen MT, Ibrahim YA, Almak ME, Ali HA, Abugrain AA, Almahal MA, MohamedSharif AA, Tahir MY, Malik SM, Eldirdiri Abdelrahman H, Khidir RJ, Mohamed MT, Abdalla A, Elsayed LEO, Lesage S, Corvol JC, Seidi O, Wüllner U. | 06/15/2023 |
Substitution of PINK1 Gly411 modulates substrate receptivity and turnover. | Substitution of PINK1 Gly411 modulates substrate receptivity and turnover. Fiesel FC, Fričová D, Hayes CS, Coban MA, Hudec R, Bredenberg JM, Broadway BJ, Markham BN, Yan T, Boneski PK, Fiorino G, Watzlawik JO, Hou X, McCarty AM, Lewis-Tuffin LJ, Zhong J, Madden BJ, Ordureau A, An H, Puschmann A, Wszolek ZK, Ross OA, Harper JW, Caulfield TR, Springer W., Free PMC Article | 06/14/2023 |
RHOA, a small G-protein, signals to mitophagy through regulation of PINK1 protein stability and protects cardiomyocytes against ischemia. | RHOA, a small G-protein, signals to mitophagy through regulation of PINK1 protein stability and protects cardiomyocytes against ischemia. Tu M, Miyamoto S., Free PMC Article | 06/14/2023 |
PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool. | PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool. Chen B, Das NK, Talukder I, Singhal R, Castillo C, Andren A, Mancias JD, Lyssiotis CA, Shah YM., Free PMC Article | 06/13/2023 |
PINK1-PRKN mediated mitophagy: differences between in vitro and in vivo models. | PINK1-PRKN mediated mitophagy: differences between in vitro and in vivo models. Han R, Liu Y, Li S, Li XJ, Yang W., Free PMC Article | 06/5/2023 |
MicroRNA-593-5p contributes to cell death following exposure to 1-methyl-4-phenylpyridinium by targeting PTEN-induced putative kinase 1. | MicroRNA-593-5p contributes to cell death following exposure to 1-methyl-4-phenylpyridinium by targeting PTEN-induced putative kinase 1. Yoo M, Choi DC, Murphy A, Ahsan AM, Junn E., Free PMC Article | 06/2/2023 |
Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis. | Inhibition of PINK1-Mediated Mitophagy Contributes to Postoperative Cognitive Dysfunction through Activation of Caspase-3/GSDME-Dependent Pyroptosis. Wang W, Zhao B, Gao W, Song W, Hou J, Zhang L, Xia Z. | 04/7/2023 |
Mitochondrial ROS driven by NOX4 upregulation promotes hepatocellular carcinoma cell survival after incomplete radiofrequency ablation by inducing of mitophagy via Nrf2/PINK1. | Mitochondrial ROS driven by NOX4 upregulation promotes hepatocellular carcinoma cell survival after incomplete radiofrequency ablation by inducing of mitophagy via Nrf2/PINK1. Peng C, Li X, Ao F, Li T, Guo J, Liu J, Zhang X, Gu J, Mao J, Zhou B., Free PMC Article | 03/28/2023 |
Targeting ATAD3A-PINK1-mitophagy axis overcomes chemoimmunotherapy resistance by redirecting PD-L1 to mitochondria. | Targeting ATAD3A-PINK1-mitophagy axis overcomes chemoimmunotherapy resistance by redirecting PD-L1 to mitochondria. Xie XQ, Yang Y, Wang Q, Liu HF, Fang XY, Li CL, Jiang YZ, Wang S, Zhao HY, Miao JY, Ding SS, Liu XD, Yao XH, Yang WT, Jiang J, Shao ZM, Jin G, Bian XW., Free PMC Article | 03/7/2023 |
PINK1 regulates apoptosis of osteosarcoma as the target gene of cisplatin. | PINK1 regulates apoptosis of osteosarcoma as the target gene of cisplatin. Si Z, Shen Z, Luan F, Yan J., Free PMC Article | 02/27/2023 |