Cooperation between SIX1 and DHX9 transcriptionally regulates integrin-focal adhesion signaling mediated metastasis and sunitinib resistance in KIRC. | Cooperation between SIX1 and DHX9 transcriptionally regulates integrin-focal adhesion signaling mediated metastasis and sunitinib resistance in KIRC. Huang S, Hu J, Hu M, Hou Y, Zhang B, Liu J, Liu X, Chen Z, Wang L. | 10/1/2024 |
BCLAF1 drives esophageal squamous cell carcinoma progression through regulation of YTHDF2-dependent SIX1 mRNA degradation. | BCLAF1 drives esophageal squamous cell carcinoma progression through regulation of YTHDF2-dependent SIX1 mRNA degradation. Zhang P, Zhang W, Wang X, Li L, Lin Y, Wu N, Mao R, Lin J, Kang M, Ding C. | 08/6/2024 |
Adipose Mesenchymal Stem Cell-derived Exosomes Enhanced Glycolysis through the SIX1/HBO1 Pathway against Oxygen and Glucose Deprivation Injury in Human Umbilical Vein Endothelial Cells. | Adipose Mesenchymal Stem Cell-derived Exosomes Enhanced Glycolysis through the SIX1/HBO1 Pathway against Oxygen and Glucose Deprivation Injury in Human Umbilical Vein Endothelial Cells. Zhang X, Zhang X, Chen L, Zhao J, Raj A, Wang Y, Li S, Zhang C, Yang J, Sun D. | 06/27/2024 |
SIX1 amplification modulates stemness and tumorigenesis in breast cancer. | SIX1 amplification modulates stemness and tumorigenesis in breast cancer. Guo L, Li F, Liu H, Kong D, Chen C, Sun S., Free PMC Article | 01/31/2024 |
Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumor. | Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumor. Stevenson MJ, Phanor SK, Patel U, Gisselbrecht SS, Bulyk ML, O'Brien LL., Free PMC Article | 11/22/2023 |
Phenotypic and molecular basis of SIX1 variants linked to non-syndromic deafness and atypical branchio-otic syndrome in South Korea. | Phenotypic and molecular basis of SIX1 variants linked to non-syndromic deafness and atypical branchio-otic syndrome in South Korea. Lee S, Yun Y, Cha JH, Han JH, Lee DH, Song JJ, Park MK, Lee JH, Oh SH, Choi BY, Lee SY., Free PMC Article | 10/26/2023 |
[Effect of Inhibiting SIX1 Expression on Drug-resistance of Acute Myeloid Leukemia Cell Line HL-60/ADR Cells]. | [Effect of Inhibiting SIX1 Expression on Drug-resistance of Acute Myeloid Leukemia Cell Line HL-60/ADR Cells]. Li LY, Nie ZY, Zhang XY, Luo JM, Yang L, Wang Q. | 08/9/2023 |
Association of SIX1-SIX6 polymorphisms with peripapillary retinal nerve fibre layer thickness in children. | Association of SIX1-SIX6 polymorphisms with peripapillary retinal nerve fibre layer thickness in children. Lu SY, Zhang XJ, Wang YM, Yuan N, Kam KW, Chan PP, Tam PO, Yip WW, Young AL, Tham CC, Pang CP, Yam JC, Chen LJ. | 07/27/2023 |
FOXC2-induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression. | FOXC2-induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression. Zou J, Huang Y, Chen Y, Wu Z, Xie H, Zhou H, Xing C. | 07/21/2023 |
LRRC75A-AS1 delivered by M2 macrophage exosomes promotes cervical cancer progression via enhancing SIX1 expression. | LRRC75A-AS1 delivered by M2 macrophage exosomes promotes cervical cancer progression via enhancing SIX1 expression. Sui HY, Cui XY, Shi CX, Yan ZP, Li HC, Wang F., Free PMC Article | 06/7/2023 |
The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer. | The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer. Ge W, Meng L, Cao S, Hou C, Zhu X, Huang D, Li Q, Peng Y, Jiang K., Free PMC Article | 03/27/2023 |
Lack of association between SIX1/SIX6 locus polymorphisms and pseudoexfoliation syndrome in a population from the Republic of Korea. | Lack of association between SIX1/SIX6 locus polymorphisms and pseudoexfoliation syndrome in a population from the Republic of Korea. Lee YC, Lee MY, Shin HY., Free PMC Article | 01/11/2023 |
Impairment of a NIK-SIX Feedback Axis Results in Dysregulation of Intestinal Immune Homeostasis and Promotes Early-onset Fatal Spontaneous Colitis. | Impairment of a NIK-SIX Feedback Axis Results in Dysregulation of Intestinal Immune Homeostasis and Promotes Early-onset Fatal Spontaneous Colitis. Zhao YX, Mei H, Huang YX, Chen JQ. | 10/15/2022 |
Association of Polymorphisms at the SIX1/SIX6 Locus With Normal Tension Glaucoma in a Korean Population. | Association of Polymorphisms at the SIX1/SIX6 Locus With Normal Tension Glaucoma in a Korean Population. Shin HY, Lee YC, Lee MY. | 09/17/2022 |
Homeoprotein SIX1 compromises antitumor immunity through TGF-beta-mediated regulation of collagens. | Homeoprotein SIX1 compromises antitumor immunity through TGF-β-mediated regulation of collagens. Liu W, Gao M, Li L, Chen Y, Fan H, Cai Q, Shi Y, Pan C, Liu J, Cheng LS, Yang H, Cheng G., Free PMC Article | 04/9/2022 |
Secondary structures, dynamics, and DNA binding of the homeodomain of human SIX1. | Secondary structures, dynamics, and DNA binding of the homeodomain of human SIX1. Li Y, Ng EY, Loh YR, Gea CY, Huang Q, Li Q, Kang C. | 03/19/2022 |
Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease. | Generation of a new six1-null line in Xenopus tropicalis for study of development and congenital disease. Coppenrath K, Tavares ALP, Shaidani NI, Wlizla M, Moody SA, Horb M., Free PMC Article | 03/19/2022 |
Phenotype-genotype correlation in patients with typical and atypical branchio-oto-renal syndrome. | Phenotype-genotype correlation in patients with typical and atypical branchio-oto-renal syndrome. Masuda M, Kanno A, Nara K, Mutai H, Morisada N, Iijima K, Morimoto N, Nakano A, Sugiuchi T, Okamoto Y, Masuda S, Katsunuma S, Ogawa K, Matsunaga T., Free PMC Article | 03/5/2022 |
Unexpected role of SIX1 variants in craniosynostosis: expanding the phenotype of SIX1-related disorders. | Unexpected role of SIX1 variants in craniosynostosis: expanding the phenotype of SIX1-related disorders. Calpena E, Wurmser M, McGowan SJ, Atique R, Bertola DR, Cunningham ML, Gustafson JA, Johnson D, Morton JEV, Passos-Bueno MR, Timberlake AT, Lifton RP, Wall SA, Twigg SRF, Maire P, Wilkie AOM., Free PMC Article | 03/5/2022 |
Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse. | Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse. Ciceri S, Montalvão-de-Azevedo R, Tajbakhsh A, Bertolotti A, Spagnuolo RD, Boschetti L, Capasso M, D'Angelo P, Serra A, Diomedi-Camassei F, Meli M, Nantron M, Quarello P, Buccoliero AM, Tamburini A, Ciniselli CM, Verderio P, Collini P, Radice P, Spreafico F, Perotti D. | 02/26/2022 |
Long non-coding RNA (LncRNA) CASC9/microRNA(miR)-590-3p/sine oculis homeobox 1 (SIX1)/NF-kappaB axis promotes proliferation and migration in breast cancer. | Long non-coding RNA (LncRNA) CASC9/microRNA(miR)-590-3p/sine oculis homeobox 1 (SIX1)/NF-κB axis promotes proliferation and migration in breast cancer. Chang J, Zhang Y, Ye X, Guo H, Lu K, Liu Q, Guo Y., Free PMC Article | 02/19/2022 |
A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance. | A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance. Liao Y, Liu Y, Shao Z, Xia X, Deng Y, Cai J, Yao L, He J, Yu C, Hu T, Sun W, Liu F, Tang D, Liu J, Huang H. | 12/25/2021 |
SIX1 transcription factor: A review of cellular functions and regulatory dynamics. | SIX1 transcription factor: A review of cellular functions and regulatory dynamics. Rafiq A, Aashaq S, Jan I, Beigh MA. | 12/25/2021 |
Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4alpha and SIX1/4. | Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4α and SIX1/4. Camolotto SA, Belova VK, Torre-Healy L, Vahrenkamp JM, Berrett KC, Conway H, Shea J, Stubben C, Moffitt R, Gertz J, Snyder EL., Free PMC Article | 12/4/2021 |
Silencing SIX1 inhibits epithelial mesenchymal transition through regulating TGF-beta/Smad2/3 signaling pathway in papillary thyroid carcinoma. | Silencing SIX1 inhibits epithelial mesenchymal transition through regulating TGF-β/Smad2/3 signaling pathway in papillary thyroid carcinoma. Min WP, Wei XF. | 11/13/2021 |