| Morphological and biological properties of silica nanoparticles for CRTC3-siRNA delivery and downregulation of the RGS2 expression in preadipocytes. | Morphological and biological properties of silica nanoparticles for CRTC3-siRNA delivery and downregulation of the RGS2 expression in preadipocytes.
Mares-García AS, Ortiz Magdaleno M, Gordillo-Moscoso A, Cárdenas-Galindo MG, Ávila Hernández IN, Escobar-García DM, Márquez-Lucero A, Pozos-Guillén A. | 02/26/2022 |
| TORC2/3-mediated DUSP1 upregulation is essential for human decidualization. | TORC2/3-mediated DUSP1 upregulation is essential for human decidualization.
Xu C, Zhao W, Huang X, Jiang Z, Liu L, Cui L, Li X, Li D, Du M. | 01/8/2022 |
| Colorectal cancer risk variants rs10161980 and rs7495132 are associated with cancer survival outcome by a recessive mode of inheritance. | Colorectal cancer risk variants rs10161980 and rs7495132 are associated with cancer survival outcome by a recessive mode of inheritance.
He Y, Timofeeva M, Zhang X, Xu W, Li X, Din FVN, Svinti V, Farrington SM, Campbell H, Dunlop MG, Theodoratou E., Free PMC Article | 11/13/2021 |
| Pancreatic mucoepidermoid carcinoma does not have CRTC1/3-MAML2 fusion gene and MAML2 gene rearrangement. | "Pancreatic Mucoepidermoid Carcinoma" Is not a Pancreatic Counterpart of CRTC1/3-MAML2 Fusion Gene-related Mucoepidermoid Carcinoma of the Salivary Gland, and May More Appropriately be Termed Pancreatic Adenosquamous Carcinoma With Mucoepidermoid Carcinoma-like Features.
Saeki K, Ohishi Y, Matsuda R, Mochidome N, Miyasaka Y, Yamamoto H, Koga Y, Maehara Y, Nakamura M, Oda Y. | 09/7/2019 |
| CRTC3-MAML2 gene fusion occurs in hidradenomas. | A novel fusion gene CRTC3-MAML2 in hidradenoma: histopathological significance.
Kuma Y, Yamada Y, Yamamoto H, Kohashi K, Ito T, Furue M, Oda Y. | 10/20/2018 |
| CRTC3 polymorphism was associated with the onset of acute coronary syndrome in Han Chinese patients, which may be related to the imbalance of the lipid metabolism | Cyclic adenosine monophosphate-regulated transcriptional co-activator 3 polymorphism in Chinese patients with acute coronary syndrome.
Zhu L, Wang Y, Jiang J, Zhou R, Ye J., Free PMC Article | 07/21/2018 |
| findings suggest further characterization of MECs is needed before considering the CRTC1/3-MAML2 gene fusion as a prognostic biomarker | Correlation of Crtc1/3-Maml2 fusion status, grade and survival in mucoepidermoid carcinoma.
Birkeland AC, Foltin SK, Michmerhuizen NL, Hoesli RC, Rosko AJ, Byrd S, Yanik M, Nor JE, Bradford CR, Prince ME, Carey TE, McHugh JB, Spector ME, Brenner JC., Free PMC Article | 03/31/2018 |
| revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions in cutaneous hidradenoma | Cutaneous hidradenoma: a study of 21 neoplasms revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions.
Kyrpychova L, Kacerovska D, Vanecek T, Grossmann P, Michal M, Kerl K, Kazakov DV. | 03/4/2017 |
| The CRTC3 polymorphism rs3862434 is associated with the plasma level of total cholesterol, and rs11635252 is associated with the risks of overweight and hypertriglyceridemia in a Chinese Han population. | CRTC3 polymorphisms were associated with the plasma level of total cholesterol and the risks of overweight and hypertriglyceridemia in a Chinese Han population.
Ou Z, Wang G, Li Q, Ma Z, Dai M, Zou F. | 08/30/2014 |
| Metaplastic Warthin tumor and metaplastic pleomorphic adenoma of salivary glands did not harbor CRTC1-MAML2 and CRTC3-MAML2 fusion transcripts, respectively, or MAML2 gene rearrangement. | CRTC1-MAML2 and CRTC3-MAML2 fusions were not detected in metaplastic Warthin tumor and metaplastic pleomorphic adenoma of salivary glands.
Skálová A, Vanecek T, Simpson RH, Vazmitsel MA, Majewska H, Mukensnabl P, Hauer L, Andrle P, Hosticka L, Grossmann P, Michal M. | 12/14/2013 |
| mucoepidermoid carcinoma of the salivary glands positive for CRTC1-MAML2 or CRTC3-MAML2 fusion formed a favourable tumour subset that was distinct from fusion-negative cases | Impact of CRTC1/3-MAML2 fusions on histological classification and prognosis of mucoepidermoid carcinoma.
Okumura Y, Miyabe S, Nakayama T, Fujiyoshi Y, Hattori H, Shimozato K, Inagaki H. | 12/3/2011 |
| CRTC3 plays a selective role in mitochondrial biogenesis in response to rotenone | Role of cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) in the initiation of mitochondrial biogenesis and stress response in liver cells.
Than TA, Lou H, Ji C, Win S, Kaplowitz N., Free PMC Article | 09/3/2011 |
| As a common human CRTC3 variant with increased transcriptional activity is associated with adiposity in two distinct Mexican-American cohorts, results suggest that adipocyte CRTC3 may play a role in the development of obesity in humans | CRTC3 links catecholamine signalling to energy balance.
Song Y, Altarejos J, Goodarzi MO, Inoue H, Guo X, Berdeaux R, Kim JH, Goode J, Igata M, Paz JC, Hogan MF, Singh PK, Goebel N, Vera L, Miller N, Cui J, Jones MR, CHARGE Consortium, GIANT Consortium, Chen YD, Taylor KD, Hsueh WA, Rotter JI, Montminy M., Free PMC Article | 02/26/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Mucoepidermoid carcinomas possessing CRTC3-MAML2 fusion may be associated with favorable clinicopathological features and patients may be younger than those with CRTC1-MAML2 fusion or those with no detectable gene fusion. | Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma.
Nakayama T, Miyabe S, Okabe M, Sakuma H, Ijichi K, Hasegawa Y, Nagatsuka H, Shimozato K, Inagaki H. | 02/1/2010 |
| study reports for the first time a CRTC3-MAML2 fusion gene in a mucoepidermoid carcinoma, as determined by RT-PCR and sequencing. | A new type of MAML2 fusion in mucoepidermoid carcinoma.
Fehr A, Röser K, Heidorn K, Hallas C, Löning T, Bullerdiek J. | 01/21/2010 |
| BCL3 functions as a repressor of HTLV-1 LTR-mediated transcription through interactions with TORC3 | BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3.
Hishiki T, Ohshima T, Ego T, Shimotohno K. | 01/21/2010 |
| transducer of regulated cyclic AMP-response element-binding protein 3 (TORC3), a co-activator of CREB, is involved in Tax-induced transcriptional activation from the HTLV-I LTR | Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3.
Koga H, Ohshima T, Shimotohno K. | 01/21/2010 |
| These results strongly suggest that TORCs play a key role in linking these external signals to the transcriptional program of adaptive mitochondrial biogenesis by activating PGC-1alpha gene transcription. | Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.
Wu Z, Huang X, Feng Y, Handschin C, Feng Y, Gullicksen PS, Bare O, Labow M, Spiegelman B, Stevenson SC., Free PMC Article | 01/21/2010 |