| Single-cell analysis reveals androgen receptor regulates the ER-to-Golgi trafficking pathway with CREB3L2 to drive prostate cancer progression. | Single-cell analysis reveals androgen receptor regulates the ER-to-Golgi trafficking pathway with CREB3L2 to drive prostate cancer progression.
Hu L, Chen X, Narwade N, Lim MGL, Chen Z, Tennakoon C, Guan P, Chan UI, Zhao Z, Deng M, Xu X, Sung WK, Cheung E. | 01/8/2022 |
| MicroRNA-92b-3p promotes the progression of liver fibrosis by targeting CREB3L2 through the JAK/STAT signaling pathway. | MicroRNA-92b-3p promotes the progression of liver fibrosis by targeting CREB3L2 through the JAK/STAT signaling pathway.
Huang W, Ji R, Ge S, Zhou D, Liu Z, Sun Y, Huang W, Lu C. | 11/6/2021 |
| Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells. | Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells.
Oh-Hashi K, Yamamoto A, Murase R, Hirata Y., Free PMC Article | 04/24/2021 |
| found BBF2H7-derived small peptide fragments located between the site-1 protease and site-1 protease cleavage sites in cells exposed to ER stress | Production of BBF2H7-derived small peptide fragments via endoplasmic reticulum stress-dependent regulated intramembrane proteolysis.
Matsuhisa K, Saito A, Cai L, Kaneko M, Okamoto T, Sakaue F, Asada R, Urano F, Yanagida K, Okochi M, Kudo Y, Matsumoto M, Nakayama KI, Imaizumi K. | 07/11/2020 |
| Transduction with BBF2H7/CREB3L2 upregulates SEC23A protein in erythroblasts and partially corrects the hypo-glycosylation phenotype associated with CDAII. | Transduction with BBF2H7/CREB3L2 upregulates SEC23A protein in erythroblasts and partially corrects the hypo-glycosylation phenotype associated with CDAII.
Pellegrin S, Haydn-Smith KL, Hampton-O'Neil LA, Hawley BR, Heesom KJ, Fermo E, Bianchi P, Toye AM., Free PMC Article | 01/4/2020 |
| UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage-specific manner. | UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage-specific manner.
Ishikawa T, Toyama T, Nakamura Y, Tamada K, Shimizu H, Ninagawa S, Okada T, Kamei Y, Ishikawa-Fujiwara T, Todo T, Aoyama E, Takigawa M, Harada A, Mori K., Free PMC Article | 09/16/2017 |
| These data suggest that the secreted luminal BBF2H7 C-terminus is involved in Hedgehog ligand-dependent cancer cell proliferation through activation of Hedgehog signaling. BBF2H7 C-terminus may be a novel target for the development of anticancer drugs. | Promotion of Cancer Cell Proliferation by Cleaved and Secreted Luminal Domains of ER Stress Transducer BBF2H7.
Iwamoto H, Matsuhisa K, Saito A, Kanemoto S, Asada R, Hino K, Takai T, Cui M, Cui X, Kaneko M, Arihiro K, Sugiyama K, Kurisu K, Matsubara A, Imaizumi K., Free PMC Article | 02/20/2016 |
| Fbxw7 controls osteogenesis and chondrogenesis by targeting OASIS and BBF2H7, respectively, for degradation. | F-box and WD repeat domain-containing-7 (Fbxw7) protein targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation.
Yumimoto K, Matsumoto M, Onoyama I, Imaizumi K, Nakayama KI., Free PMC Article | 12/7/2013 |
| the BBF2H7-mediated Sec23A pathway is required for ER-to-Golgi procollagen trafficking to promote collagen synthesis | BBF2H7-mediated Sec23A pathway is required for endoplasmic reticulum-to-Golgi trafficking in dermal fibroblasts to promote collagen synthesis.
Ishikura-Kinoshita S, Saeki H, Tsuji-Naito K. | 10/6/2012 |
| FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1. | FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1.
Möller E, Hornick JL, Magnusson L, Veerla S, Domanski HA, Mertens F. | 09/17/2011 |
| We characterized a widely expressed transcript of CREB3L2 generated by an intronic polyadenylation site in intron 4 of the gene. | Characterization of an alternative transcript of the human CREB3L2 gene.
Panagopoulos I, Monsef N, Collin A, Mertens F. | 02/26/2011 |
| The human Creb3L2 can activate SPCG transcription in a heterologous system(Drosophila embryos), which suggests a general and direct role for this family of bZip transcription factors in mediating high-level secretory capacity. | The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity.
Fox RM, Hanlon CD, Andrew DJ., Free PMC Article | 12/11/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Fusion of the FUS and CREB3L2 genes in a supernumerary ring chromosome is associated with low-grade fibromyxoid sarcoma. | Fusion of the FUS and CREB3L2 genes in a supernumerary ring chromosome in low-grade fibromyxoid sarcoma.
Bartuma H, Möller E, Collin A, Domanski HA, Von Steyern FV, Mandahl N, Mertens F. | 06/14/2010 |
| We characterized the promoter region of CREB3L2, showing that it is asymmetrically bidirectional | Characterization of the human CREB3L2 gene promoter.
Panagopoulos I, Mertens F. | 01/21/2010 |
| findings identify a novel CREB3L2-PPARgamma gene fusion mutation in thyroid carcinoma and reveal a thyroid signaling pathway that is regulated by intramembrane proteolysis and disrupted in cancer | CREB3L2-PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis.
Lui WO, Zeng L, Rehrmann V, Deshpande S, Tretiakova M, Kaplan EL, Leibiger I, Leibiger B, Enberg U, Höög A, Larsson C, Kroll TG. | 01/21/2010 |
| CREB3L2 is not only structurally, but also functionally very similar to CREB3L1. | Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimera.
Panagopoulos I, Möller E, Dahlén A, Isaksson M, Mandahl N, Vlamis-Gardikas A, Mertens F. | 01/21/2010 |
| Presence of FUS/CREB3L2 and FUS/CREB3L1 in low-grade fibromyxoid sarcoma and sclerosing epithelioid fibrosarcoma suggests these neoplasms may be related. | Translocation-positive low-grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group.
Guillou L, Benhattar J, Gengler C, Gallagher G, Ranchère-Vince D, Collin F, Terrier P, Terrier-Lacombe MJ, Leroux A, Marquès B, Aubain Somerhausen Nde S, Keslair F, Pedeutour F, Coindre JM. | 01/21/2010 |
| BBF2H7 was fused with FUS in a low grade myxoid liposarcoma. | Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma.
Storlazzi CT, Mertens F, Nascimento A, Isaksson M, Wejde J, Brosjo O, Mandahl N, Panagopoulos I. | 01/21/2010 |
| BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulumm stress transducer. | BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer.
Kondo S, Saito A, Hino S, Murakami T, Ogata M, Kanemoto S, Nara S, Yamashita A, Yoshinaga K, Hara H, Imaizumi K., Free PMC Article | 01/21/2010 |