| Identification of Tensin-3 as a MALT1 substrate that controls B cell adhesion and lymphoma dissemination. | Identification of Tensin-3 as a MALT1 substrate that controls B cell adhesion and lymphoma dissemination.
Juilland M, Alouche N, Ubezzi I, Gonzalez M, Rashid HO, Scarpellino L, Erdmann T, Grau M, Lenz G, Luther SA, Thome M., Free PMC Article | 01/3/2024 |
| Tensin-3 is involved in osteogenic versus adipogenic fate of human bone marrow stromal cells. | Tensin-3 is involved in osteogenic versus adipogenic fate of human bone marrow stromal cells.
Zhang S, van de Peppel J, Koedam M, van Leeuwen JPTM, van der Eerden BCJ., Free PMC Article | 09/6/2023 |
| Abnormal TNS3 gene methylation in patients with congenital scoliosis. | Abnormal TNS3 gene methylation in patients with congenital scoliosis.
Wu Y, Zhang HQ, Tang M, Guo C, Liu S, Li J, Wang Y, Xiao L, Yang G., Free PMC Article | 09/3/2022 |
| Tensin Regulates Fundamental Biological Processes by Interacting with Integrins of Tonsil-Derived Mesenchymal Stem Cells. | Tensin Regulates Fundamental Biological Processes by Interacting with Integrins of Tonsil-Derived Mesenchymal Stem Cells.
Park GC, Kim JM, Shin SC, Cheon YI, Sung ES, Lee M, Lee JC, Lee BJ., Free PMC Article | 08/20/2022 |
| PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins. | PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.
Zuidema A, Atherton P, Kreft M, Hoekman L, Bleijerveld OB, Nagaraj N, Chen N, Fässler R, Sonnenberg A., Free PMC Article | 06/18/2022 |
| MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity. | MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity.
Zheng JY, Wang CY, Gao C, Xiao Q, Huang CW, Wu M, Li LY., Free PMC Article | 09/25/2021 |
| Tensin-3 Regulates Integrin-Mediated Proliferation and Differentiation of Tonsil-Derived Mesenchymal Stem Cells. | Tensin-3 Regulates Integrin-Mediated Proliferation and Differentiation of Tonsil-Derived Mesenchymal Stem Cells.
Park GC, Kim HS, Park HY, Seo Y, Kim JM, Shin SC, Kwon HK, Sung ES, Lee JC, Lee BJ., Free PMC Article | 08/15/2020 |
| These findings suggested a critical role of MSI1-TNS3 axis in regulating glioblastoma migration. | Musashi-1 Enhances Glioblastoma Cell Migration and Cytoskeletal Dynamics through Translational Inhibition of Tensin3.
Chen HY, Lin LT, Wang ML, Laurent B, Hsu CH, Pan CM, Jiang WR, Chen PY, Ma HI, Chen YW, Huang PI, Chiou A, Chiou SH., Free PMC Article | 03/23/2019 |
| Our work identifies Tns3 as a crucial focal adhesion component regulated by, and functionally contributing to, the switch between adhesive and non-adhesive states in MDA-MB-468 cancer cells. | A dual phenotype of MDA-MB-468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity.
Veß A, Blache U, Leitner L, Kurz ARM, Ehrenpfordt A, Sixt M, Posern G. | 03/31/2018 |
| A phosphorylation-mediated molecular switch comprising DLC), TNS3, PTEN and PI3K controls the spatiotemporal activation of Rac1 and RhoA, thereby initiating directional cell migration induced by growth factors. | A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration.
Cao X, Kaneko T, Li JS, Liu AD, Voss C, Li SS., Free PMC Article | 04/23/2016 |
| The depletion of tensin-3 suppressed breast cancer cell invasiveness. | SUV420H2 suppresses breast cancer cell invasion through down regulation of the SH2 domain-containing focal adhesion protein tensin-3.
Shinchi Y, Hieda M, Nishioka Y, Matsumoto A, Yokoyama Y, Kimura H, Matsuura S, Matsuura N. | 08/15/2015 |
| The phenotypic changes observed in proband cells may arise from TNS3 haploinsufficiency, causing partial loss of full-length Tensin3 protein. Tensin3 plays a rol in cytoskeletal organisation and cell motility. | Functional characterisation of human cells harbouring a novel t(2p;7p) translocation involving TNS3 and EXOC6B genes.
Ludwig D, Carter J, Smith JR, Borsani G, Barlati S, Hafizi S., Free PMC Article | 09/13/2014 |
| These results reveal a differential methylation pattern in the TNS3 promoter occurring in human renal cell carcinoma. | CpG dinucleotide-specific hypermethylation of the TNS3 gene promoter in human renal cell carcinoma.
Carter JA, Górecki DC, Mein CA, Ljungberg B, Hafizi S., Free PMC Article | 02/22/2014 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Tensin3 mRNA is expressed abundantly in all twelve functional adenomas at almost the same level as in normal thyroid tissue. | Increased expression levels of tensin3 mRNA in thyroid functional adenomas as compared to non-functioning adenomas.
Maeda I, Yamada H, Takano T, Nishihara E, Ito Y, Matsuzuka F, Miya A, Kobayashi K, Yoshida H, Miyauchi A, Hidaka Y. | 01/21/2010 |
| Tensins may represent a novel group of metastasis suppressors in the kidney, the loss of which leads to greater tumor cell motility and consequent metastasis. | Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.
Martuszewska D, Ljungberg B, Johansson M, Landberg G, Oslakovic C, Dahlbäck B, Hafizi S., Free PMC Article | 01/21/2010 |
| TNS3-EXOC6B and EXOC6B-TNS3 fusion transcripts are detected in a premature male newborn with a complex multisystemic phenotype associated with a balanced translocation. | Cytogenetic and molecular characterization of a de-novo t(2p;7p) translocation involving TNS3 and EXOC6B genes in a boy with a complex syndromic phenotype.
Borsani G, Piovani G, Zoppi N, Bertini V, Bini R, Notarangelo L, Barlati S. | 01/21/2010 |
| Data show that EGF downregulates tensin-3 expression, and concomitantly upregulates cten, a tensin family member that lacks the actin-binding domain. | A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.
Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y. | 01/21/2010 |
| Tensin3 may function as a platform for the disassembly of EGF-related signaling complexes at focal adhesions. | Epidermal growth factor modulates tyrosine phosphorylation of a novel tensin family member, tensin3.
Cui Y, Liao YC, Lo SH. | 01/21/2010 |