| LINC00520 promotes colorectal cancer progression through miRNA-195-3p / NAT2 axis. | LINC00520 promotes colorectal cancer progression through miRNA-195-3p / NAT2 axis.
Liu H, Zhang G, Li C, Song X. | 10/8/2024 |
| Endothelial cells LEENE on noncoding RNAs in diabetic vasculopathy. | Endothelial cells LEENE on noncoding RNAs in diabetic vasculopathy.
Kallapur A, Sallam T., Free PMC Article | 02/11/2023 |
| Long noncoding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models. | Long noncoding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models.
Tang X, Luo Y, Yuan D, Calandrelli R, Malhi NK, Sriram K, Miao Y, Lou CH, Tsark W, Tapia A, Chen AT, Zhang G, Roeth D, Kalkum M, Wang ZV, Chien S, Natarajan R, Cooke JP, Zhong S, Chen ZB., Free PMC Article | 02/11/2023 |
| LINC00520 up-regulates SOX5 to promote cell proliferation and invasion by miR-4516 in human hepatocellular carcinoma. | LINC00520 up-regulates SOX5 to promote cell proliferation and invasion by miR-4516 in human hepatocellular carcinoma.
Li Q, Wang W, Yang T, Li D, Huang Y, Bai G, Li Q. | 06/18/2022 |
| LINC00520: A Potential Diagnostic and Prognostic Biomarker in Cancer. | LINC00520: A Potential Diagnostic and Prognostic Biomarker in Cancer.
Zhang Q, Shen J, Wu Y, Ruan W, Zhu F, Duan S., Free PMC Article | 05/14/2022 |
| SP1-induced overexpression of LINC00520 facilitates non-small cell lung cancer progression through miR-577/CCNE2 pathway and predicts poor prognosis. | SP1-induced overexpression of LINC00520 facilitates non-small cell lung cancer progression through miR-577/CCNE2 pathway and predicts poor prognosis.
Wang JF, Xi ZN, Su HJ, Bao Z, Qiao YH. | 10/9/2021 |
| Characterization of lncRNA LINC00520 and functional polymorphisms associated with breast cancer susceptibility in Chinese Han population. | Characterization of lncRNA LINC00520 and functional polymorphisms associated with breast cancer susceptibility in Chinese Han population.
Guo Q, Xu L, Peng R, Ma Y, Wang Y, Chong F, Song M, Dai L, Song C., Free PMC Article | 04/24/2021 |
| Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis. | Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant melanoma by inducing the miR-125b-5p/EIF5A2 axis.
Luan W, Ding Y, Yuan H, Ma S, Ruan H, Wang J, Lu F, Bu X., Free PMC Article | 02/6/2021 |
| Overexpression of LINC00520 contributes to the aggravation of Acute kidney injury by targeting miR-27b-3p/ OSMR. | LINC00520 targeting miR-27b-3p regulates OSMR expression level to promote acute kidney injury development through the PI3K/AKT signaling pathway.
Tian X, Ji Y, Liang Y, Zhang J, Guan L, Wang C. | 05/30/2020 |
| LINC00520 expression is up-regulated in nasopharyngeal carcinoma (NPC) tissues and cells, and its overexpression is associated with poor prognosis. Its knockdown showed tumor-suppressive roles via repressing NPC cell proliferation and tumor growth. LINC00520 mediates its function through functioning as a ceRNA for miR-26b, releasing the miR-26b inhibitory role for its target gene USP39. | Long non-coding RNA 520 is a negative prognostic biomarker and exhibits pro-oncogenic function in nasopharyngeal carcinoma carcinogenesis through regulation of miR-26b-3p/USP39 axis.
Xie T, Pi G, Yang B, Ren H, Yu J, Ren Q, Zhou X, Hu D, Zhang H, Zhang H, Zhang Q, Hu L, Li Y, Zhou F. | 06/29/2019 |
| LINC00520-targeted EGFR inhibition might result in the inactivation of the PI3K/Akt pathway, thus inhibiting cutaneous squamous cell carcinoma (cSCC) development. | Long noncoding RNA LINC00520 prevents the progression of cutaneous squamous cell carcinoma through the inactivation of the PI3K/Akt signaling pathway by downregulating EGFR.
Mei XL, Zhong S., Free PMC Article | 06/1/2019 |
| Long non-coding RNA LEENE (gene name LINC00520, aka C14orf34) enhances endothelial nitric oxide synthase (eNOS) transcription and endothelial cells (ECs) function. | Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function.
Miao Y, Ajami NE, Huang TS, Lin FM, Lou CH, Wang YT, Li S, Kang J, Munkacsi H, Maurya MR, Gupta S, Chien S, Subramaniam S, Chen Z., Free PMC Article | 03/10/2018 |
| Expression of LINC00520 is regulated by oncogenic Src, PIK3CA and STAT3, and may contribute to the molecular etiology of breast cancer. | LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer.
Henry WS, Hendrickson DG, Beca F, Glass B, Lindahl-Allen M, He L, Ji Z, Struhl K, Beck AH, Rinn JL, Toker A., Free PMC Article | 02/17/2018 |