A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development.
Zhang R, Wu M, Xiang D, Zhu J, Zhang Q, Zhong H, Peng Y, Wang Z, Ma G, Li G, Liu F, Ye W, Shi R, Zhou X, Babarinde IA, Su H, Chen J, Zhang X, Qin D, Hutchins AP, Pei D, Li D.

Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance.
Boughanem H, Pilo J, García-Flores LA, Arranz I, Ramos-Fernandez M, Ortega-Castan M, Crujeiras AB, Sandoval J, Macias-Gonzalez M., Free PMC Article

Sfrp2 promotes renal dysfunction of diabetic kidney disease via modulating Fzd5-induced cytosolic calcium ion concentration and CaMKII/Mek/Erk pathway in mesangial cells.
Lv D, Lin Z, Liao X, Peng R, Liu H, Wu T, Wu K, Sun Y, Zhang Z.

Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma.
Jayabal P, Zhou F, Ma X, Bondra KM, Blackman B, Weintraub ST, Chen Y, Chévez-Barrios P, Houghton PJ, Gallie B, Shiio Y., Free PMC Article

The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway.
Yang M, Li L, Huang X, Xing H, Hong L, Jiang C., Free PMC Article

Novel method of differentiating human induced pluripotent stem cells to mature cardiomyocytes via Sfrp2.
Hsueh YC, Pratt RE, Dzau VJ, Hodgkinson CP., Free PMC Article

SFRP2 Overexpression Induces an Osteoblast-like Phenotype in Prostate Cancer Cells.
Akova Ölken E, Aszodi A, Taipaleenmäki H, Saito H, Schönitzer V, Chaloupka M, Apfelbeck M, Böcker W, Saller MM., Free PMC Article

Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from "first contact" interactions in the tumor microenvironment.
Charles Jacob HK, Signorelli R, Charles Richard JL, Kashuv T, Lavania S, Middleton A, Gomez BA, Ferrantella A, Amirian H, Tao J, Ergonul AB, Boone MM, Hadisurya M, Tao WA, Iliuk A, Kashyap MK, Garcia-Buitrago M, Dawra R, Saluja AK., Free PMC Article

Evaluation of combined detection of multigene mutation and SDC2/SFRP2 methylation in stool specimens for colorectal cancer early diagnosis.
Lin J, Zhang L, Chen M, Chen J, Wu Y, Wang T, Lu Y, Ba Z, Cheng X, Xu R, Tian T, Sun A, Zhang T, Chen M.

Downregulation of SFRP2 facilitates cancer stemness and radioresistance of glioma cells via activating Wnt/β-catenin signaling.
Wu Q, Yin X, Zhao W, Xu W, Chen L., Free PMC Article

SFRP2 induces a mesenchymal subtype transition by suppression of SOX2 in glioblastoma.
Guo M, Goudarzi KM, Abedi S, Pieber M, Sjöberg E, Behnan J, Zhang XM, Harris RA, Bartek J, Lindström MS, Nistér M, Hägerstrand D., Free PMC Article

MicroRNA-522-3p plays an oncogenic role in glioblastoma through activating Wnt/β-catenin signaling pathway via targeting SFRP2.
Zhang L, Zhang P, Tan Y, Feng Q, Zhao R.

Value of Plasma Methylated SFRP2 in Prognosis of Gastric Cancer.
Yan H, Chen W, Ge K, Mao X, Li X, Liu W, Wu J.

Secreted frizzled-related protein 2: a key player in noncanonical Wnt signaling and tumor angiogenesis.
van Loon K, Huijbers EJM, Griffioen AW., Free PMC Article

sFRP2 Supersedes VEGF as an Age-related Driver of Angiogenesis in Melanoma, Affecting Response to Anti-VEGF Therapy in Older Patients.
Fane ME, Ecker BL, Kaur A, Marino GE, Alicea GM, Douglass SM, Chhabra Y, Webster MR, Marshall A, Colling R, Espinosa O, Coupe N, Maroo N, Campo L, Middleton MR, Corrie P, Xu X, Karakousis GC, Weeraratna AT., Free PMC Article

[Value of combined detection of ITGA4 and SFRP2 gene methylation in stool DNA in diagnosis and prognostic evaluation of colorectal tumors].
Jin H, Pang L, Li H, Xu M, Yan H, Li R., Free PMC Article

Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer.
Boughanem H, Cabrera-Mulero A, Hernández-Alonso P, Clemente-Postigo M, Casanueva FF, Tinahones FJ, Morcillo S, Crujeiras AB, Macias-Gonzalez M., Free PMC Article

Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population.
Kasashima H, Duran A, Martinez-Ordoñez A, Nakanishi Y, Kinoshita H, Linares JF, Reina-Campos M, Kudo Y, L'Hermitte A, Yashiro M, Ohira M, Bao F, Tauriello DVF, Batlle E, Diaz-Meco MT, Moscat J., Free PMC Article

Hypermethylation of secreted frizzled related protein 2 gene promoter serves as a noninvasive biomarker for HBV-associated hepatocellular carcinoma.
Xiang L, Chen LM, Zhai YJ, Sun WJ, Yang JR, Fan YC, Wang K.

DNA methylation and gene expression of sFRP2, sFRP4, Dkk 1, and Wif1 during osteoblastic differentiation of bone marrow derived mesenchymal stem cells.
Mashhadikhan M, Kheiri H, Dehghanifard A.

Feasibility of Plasma-Methylated SFRP2 for Early Detection of Gastric Cancer.
Miao J, Liu Y, Zhao G, Liu X, Ma Y, Li H, Li S, Zhu Y, Xiong S, Zheng M, Fei S., Free PMC Article

Secreted Frizzled-Related Protein 2 and Extracellular Volume Fraction in Patients with Heart Failure.
Yang S, Chen H, Tan K, Cai F, Du Y, Lv W, Hu Q, Hu Y, Huang Y., Free PMC Article

SFRP2 promotes stem cells from apical papilla-mediated periodontal tissue regeneration in miniature pig.
Li G, Han N, Yang H, Zhang X, Cao Y, Cao Y, Shi R, Wang S, Fan Z.

LUCAT1 Epigenetically Downregulates the Tumor Suppressor Genes CXXC4 and SFRP2 in Gastric Cancer.
Byun HJ, Yoon JH, Lee SK., Free PMC Article

A novel plasma based early colorectal cancer screening assay base on methylated SDC2 and SFRP2.
Zhao G, Ma Y, Li H, Li S, Zhu Y, Liu X, Xiong S, Liu Y, Miao J, Fei S, Zheng M, Zhao X.