| Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes. | Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes.
Riise R, Odqvist L, Mattsson J, Monkley S, Abdillahi SM, Tyrchan C, Muthas D, Yrlid LF., Free PMC Article | 11/21/2020 |
| Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs. | Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.
Wu H, Li L, Chen KM, Homolka D, Gos P, Fleury-Olela F, McCarthy AA, Pillai RS. | 10/3/2020 |
| the BLMH gene single nucleotide polymorphism A1450G (rs1050565) influences BLMH activity and late pulmonary toxicity. | Effect of Bleomycin Hydrolase Gene Polymorphism on Late Pulmonary Complications of Treatment for Hodgkin Lymphoma.
Jóna Á, Miltényi Z, Póliska S, Bálint BL, Illés Á., Free PMC Article | 07/29/2017 |
| Ubc9 plays different roles of action in antitumor agents in chemotherapy. The process requires bleomycin hydrolase and poly(ADP-ribose) polymerase-1. The results are beneficial to deeply understanding of Ubc9 functions and for precise prediction of chemotherapy outcomes in tumors. | Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents.
Chen Y, Zhang H, He Q. | 04/8/2017 |
| Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of filaggrin gene mutations | Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.
Pellerin L, Paul C, Schmitt AM, Serre G, Simon M. | 02/7/2015 |
| This study findings suggest that Blmh interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis. | Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration.
Suszyńska-Zajczyk J, Luczak M, Marczak L, Jakubowski H. | 12/20/2014 |
| We also detected significant association between XRCC1, XRCC3, and BLHX polymorphisms and a high frequency of chromosomal damage | Association among XRCC1, XRCC3, and BLHX gene polymorphisms and chromosome instability in lymphocytes from patients with endometriosis and ovarian cancer.
Monteiro MS, Vilas Boas DB, Gigliotti CB, Salvadori DM. | 11/8/2014 |
| The caspase-dependent cleavage of BLH was confirmed by cleavage of partly-purified human bleomycin hydrolase with caspase-3. | Cleavage of bleomycin hydrolase by caspase-3 during apoptosis.
Chen Y, Xu R, Chen J, Li X, He Q. | 03/1/2014 |
| BH may play an important role during the late stage of epidermal differentiation. | Expression of bleomycin hydrolase in keratinization disorders.
Kamata Y, Maejima H, Watarai A, Saito N, Katsuoka K, Takeda A, Ishihara K. | 05/12/2012 |
| present study suggests that our new method can detect novel genes of interest and that BLMH is a suppressor gene in HCC | Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method.
Okamura Y, Nomoto S, Hayashi M, Hishida M, Nishikawa Y, Yamada S, Fujii T, Sugimoto H, Takeda S, Kodera Y, Nakao A. | 12/3/2011 |
| This first report on BLMH carrier status in Tunisia shows o association between carrying the BLMH-G genotype and Alzheimer's disease in epsilon4 negative or positive subjects. | Analysis of association between bleomycin hydrolase and apolipoprotein E polymorphism in Alzheimer's disease.
Smach MA, Charfeddine B, Lammouchi T, Othman LB, Letaief A, Nafati S, Dridi H, Bennamou S, Limem K. | 10/1/2011 |
| Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin. | Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin.
Ratovitski T, Chighladze E, Waldron E, Hirschhorn RR, Ross CA., Free PMC Article | 07/23/2011 |
| BH activity and expression were markedly decreased in AD lesional skin, suggesting a defect of the filaggrin degradation pathway in AD. | Bleomycin hydrolase is regulated biphasically in a differentiation- and cytokine-dependent manner: relevance to atopic dermatitis.
Kamata Y, Yamamoto M, Kawakami F, Tsuboi R, Takeda A, Ishihara K, Hibino T., Free PMC Article | 05/14/2011 |
| The homozygous variant G/G of BLMH gene SNP A1450G is associated with reduced survival and higher prevalence of early relapses in TC patients treated with bleomycin-containing chemotherapy. | Variation in bleomycin hydrolase gene is associated with reduced survival after chemotherapy for testicular germ cell cancer.
de Haas EC, Zwart N, Meijer C, Nuver J, Boezen HM, Suurmeijer AJ, Hoekstra HJ, van der Steege G, Sleijfer DT, Gietema JA, de Haas EC, Zwart N, Meijer C, Nuver J, Boezen HM, Suurmeijer AJ, Hoekstra HJ, van der Steege G, Sleijfer DT, Gietema JA. | 01/21/2010 |
| Significant effect of BLHX variant alleles (A/G, G/G) on the chromosome damage induced by bleomycin. | Micronuclei frequency induced by bleomycin in human peripheral lymphocytes: correlating BLHX polymorphism with mutagen sensitivity.
Maffei F, Carbone F, Angelini S, Forti GC, Norppa H, Hrelia P, Maffei F, Carbone F, Angelini S, Forti GC, Norppa H, Hrelia P. | 01/21/2010 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation in bleomycin hydrolase gene is associated with reduced survival after chemotherapy for testicular germ cell cancer.
de Haas EC, Zwart N, Meijer C, Nuver J, Boezen HM, Suurmeijer AJ, Hoekstra HJ, van der Steege G, Sleijfer DT, Gietema JA, de Haas EC, Zwart N, Meijer C, Nuver J, Boezen HM, Suurmeijer AJ, Hoekstra HJ, van der Steege G, Sleijfer DT, Gietema JA. | 04/23/2008 |
| Meta-analysis of gene-disease association. (HuGE Navigator) | Meta-analysis of genetic variability in the beta-amyloid production, aggregation and degradation metabolic pathways and the risk of Alzheimer's disease.
Llorca J, Rodríguez-Rodríguez E, Dierssen-Sotos T, Delgado-Rodríguez M, Berciano J, Combarros O. | 03/13/2008 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Genetic polymorphisms of DNA repair and xenobiotic-metabolizing enzymes: role in mutagen sensitivity.
Tuimala J, Szekely G, Gundy S, Hirvonen A, Norppa H. | 03/13/2008 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesMicronuclei frequency induced by bleomycin in human peripheral lymphocytes: correlating BLHX polymorphism with mutagen sensitivity.
Maffei F, Carbone F, Angelini S, Forti GC, Norppa H, Hrelia P, Maffei F, Carbone F, Angelini S, Forti GC, Norppa H, Hrelia P. Genetic variation in the bleomycin hydrolase gene and bleomycin-induced pulmonary toxicity in germ cell cancer patients.
Nuver J, Lutke Holzik MF, van Zweeden M, Hoekstra HJ, Meijer C, Suurmeijer AJ, Groen HJ, Hofstra RM, Sluiter WJ, Groen H, Sleijfer DT, Gietema JA. Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.
Prince JA, Feuk L, Sawyer SL, Gottfries J, Ricksten A, Nägga K, Bogdanovic N, Blennow K, Brookes AJ. Genetic risk factors of sporadic Alzheimer's disease among Chinese in Taiwan.
Hu CJ, Sung SM, Liu HC, Hsu WC, Lee LS, Lee CC, Tsai CH, Chang JG. | 03/13/2008 |
| Polymorphism is associated with neurodegenerative diseases, notably Alzheimer disease. | [Apolipoprotein E and bleomycin hydrolase. Polymorphisms: association with neurodegenerative diseases].
Nivet-Antoine V, Coulhon MP, Le Denmat C, Hamon B, Dulcire X, Lefebvre M, Piette F, Davous P, Durand D, Duchassaing D. | 01/21/2010 |