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    ERAP2 endoplasmic reticulum aminopeptidase 2 [ Homo sapiens (human) ]

    Gene ID: 64167, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response.

    The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response.
    Sæterstad S, Østvik AE, Hansen MD, Bruland T, van Beelen Granlund A., Free PMC Article

    08/21/2024
    A study of the association between single nucleotide polymorphisms of the endoplasmic reticulum aminopeptidase 2 (ERAP2) gene and the risk of ankylosing spondylitis in Egyptians.

    A study of the association between single nucleotide polymorphisms of the endoplasmic reticulum aminopeptidase 2 (ERAP2) gene and the risk of ankylosing spondylitis in Egyptians.
    Mesahel RMI, Fotoh DS, Hadhoud MM, Ali Assar MF., Free PMC Article

    05/8/2024
    A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs.

    A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs.
    Venema WJ, Hiddingh S, van Loosdregt J, Bowes J, Balliu B, de Boer JH, Ossewaarde-van Norel J, Thompson SD, Langefeld CD, de Ligt A, van der Veken LT, Krijger PHL, de Laat W, Kuiper JJW., Free PMC Article

    02/14/2024
    ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes.

    ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes.
    Tedeschi V, Paldino G, Alba J, Molteni E, Paladini F, Scrivo R, Congia M, Cauli A, Caccavale R, Paroli M, Di Franco M, Tuosto L, Sorrentino R, D'Abramo M, Fiorillo MT., Free PMC Article

    09/18/2023
    Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.

    Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.
    Marusina AI, Ji-Xu A, Le ST, Toussi A, Tsoi LC, Li Q, Luxardi G, Nava J, Downing L, Leal AR, Kuzminykh NY, Kruglinskaya O, Brüggen MC, Adamopoulos IE, Merleev AA, Gudjonsson JE, Maverakis E.

    06/26/2023
    A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2.

    A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2.
    Hur B, Wong V, Lee ED., Free PMC Article

    03/2/2023
    ERAP2 supports TCR recognition of three immunotherapy targeted tumor epitopes.

    ERAP2 supports TCR recognition of three immunotherapy targeted tumor epitopes.
    Schmidt K, Leisegang M, Kloetzel PM.

    02/25/2023
    The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities.

    The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities.
    Martín-Esteban A, Rodriguez JC, Peske D, Lopez de Castro JA, Shastri N, Sadegh-Nasseri S., Free PMC Article

    12/31/2022
    ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer.

    ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer.
    Yu P, Luo S, Cai J, Li J, Peng C., Free PMC Article

    10/29/2022
    ERAP2 is a novel target involved in autophagy and activation of pancreatic stellate cells via UPR signaling pathway.

    ERAP2 is a novel target involved in autophagy and activation of pancreatic stellate cells via UPR signaling pathway.
    Guan W, Nakata K, Sagara A, Iwamoto C, Endo S, Matsuda R, Matsumoto S, Ikenaga N, Shindo K, Moriyama T, Onishi H, Ohuchida K, Oda Y, Nakamura M.

    04/2/2022
    ERAP2 Is Associated With Immune Infiltration and Predicts Favorable Prognosis in SqCLC.

    ERAP2 Is Associated With Immune Infiltration and Predicts Favorable Prognosis in SqCLC.
    Yang Z, Tian H, Bie F, Xu J, Zhou Z, Yang J, Li R, Peng Y, Bai G, Tian Y, Chen Y, Liu L, Fan T, Xiao C, Zheng Y, Zheng B, Wang J, Li C, Gao S, He J., Free PMC Article

    02/19/2022
    ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers.

    ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers.
    Gelfman S, Monnet D, Ligocki AJ, Tabary T, Moscati A, Bai X, Freudenberg J, Cooper B, Kosmicki JA, Wolf S, Ferreira MAR, Overton J, Weyne J, Stahl EA, Baras A, Romano C, Cohen JHM, Coppola G, Brézin A, Regeneron Genetics Center., Free PMC Article

    11/27/2021
    Association of the genetic variants in the endoplasmic reticulum aminopeptidase 2 gene with ankylosing spondylitis susceptibility.

    Association of the genetic variants in the endoplasmic reticulum aminopeptidase 2 gene with ankylosing spondylitis susceptibility.
    Ebrazeh M, Ezzatifar F, Torkamandi S, Mohammadi FS, Salimifard S, Gowhari Shabgah A, Hemmatzadeh M, Aslani S, Babaie F, Jadidi-Niaragh F, Gholizadeh Navashenaq J, Mohammadi H.

    11/13/2021
    Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.

    Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
    Ferreira LC, Gomes CEM, Duggal P, De Paula Holanda I, de Lima AS, do Nascimento PRP, Jeronimo SMB., Free PMC Article

    10/30/2021
    Synergy of endoplasmic reticulum aminopeptidase 1 and 2 (ERAP1 and ERAP2) polymorphisms in atopic dermatitis: Effects on disease prevalence.

    Synergy of endoplasmic reticulum aminopeptidase 1 and 2 (ERAP1 and ERAP2) polymorphisms in atopic dermatitis: Effects on disease prevalence.
    Niepiekło-Miniewska W, Matusiak Ł, Narbutt J, Lesiak A, Kuna P, Wiśniewski A, Piekarska K, Nowak I, Kuśnierczyk P.

    10/9/2021
    ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29.

    ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29.
    Venema WJ, Hiddingh S, de Boer JH, Claas FHJ, Mulder A, den Hollander AI, Stratikos E, Sarkizova S, van der Veken LT, Janssen GMC, van Veelen PA, Kuiper JJW., Free PMC Article

    09/25/2021
    Overexpression of ERAP2N in Human Trophoblast Cells Promotes Cell Death.

    Overexpression of ERAP2N in Human Trophoblast Cells Promotes Cell Death.
    Lospinoso K, Dozmorov M, El Fawal N, Raghu R, Chae WJ, Lee ED., Free PMC Article

    09/18/2021
    ERAPs Reduce In Vitro HIV Infection by Activating Innate Immune Response.

    ERAPs Reduce In Vitro HIV Infection by Activating Innate Immune Response.
    Saulle I, Marventano I, Saresella M, Vanetti C, Garziano M, Fenizia C, Trabattoni D, Clerici M, Biasin M., Free PMC Article

    08/28/2021
    Endoplasmic reticulum aminopeptidase 2 gene single nucleotide polymorphisms in association with susceptibility to ankylosing spondylitis in an Iranian population.

    Endoplasmic reticulum aminopeptidase 2 gene single nucleotide polymorphisms in association with susceptibility to ankylosing spondylitis in an Iranian population.
    Ebrazeh M, Nojavan M, Abdi-Shayan S, Salimifard S, Dolatshahi E, Aslani S, Hemmatzadeh M, Babaie F, Ghanavatinejad A, Azizi G, Jadidi-Niaragh F, Zamani N, Mohammadi H.

    07/10/2021
    Association of ERAP2 polymorphisms in Colombian HLA-B27+ or HLA-B15+ patients with SpA and its relationship with clinical presentation: axial or peripheral predominance.

    Association of ERAP2 polymorphisms in Colombian HLA-B27+ or HLA-B15+ patients with SpA and its relationship with clinical presentation: axial or peripheral predominance.
    Londono J, Santos AM, Rueda JC, Calvo-Paramo E, Burgos-Vargas R, Vargas-Alarcon G, Martinez-Rodriguez N, Arias-Correal S, Muñoz GN, Padilla D, Cuervo F, Reyes-Martinez V, Bernal-Macías S, Villota-Eraso C, Avila-Portillo LM, Romero C, Medina JF., Free PMC Article

    07/3/2021
    Modulation of Natural HLA-B*27:05 Ligandome by Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 2 (ERAP2).

    Modulation of Natural HLA-B*27:05 Ligandome by Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 2 (ERAP2).
    Lorente E, Fontela MG, Barnea E, Martín-Galiano AJ, Mir C, Galocha B, Admon A, Lauzurica P, López D., Free PMC Article

    06/5/2021
    The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia.

    The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia.
    Seamon K, Kurlak LO, Warthan M, Stratikos E, Strauss JF 3rd, Mistry HD, Lee ED., Free PMC Article

    03/20/2021
    Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population.

    Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population.
    Li C, Li Y, Yan Z, Dai S, Liu S, Wang X, Wang J, Zhang X, Shi L, Yao Y., Free PMC Article

    01/16/2021
    Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection.

    Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection.
    Saulle I, Ibba SV, Torretta E, Vittori C, Fenizia C, Piancone F, Minisci D, Lori EM, Trabattoni D, Gelfi C, Clerici M, Biasin M., Free PMC Article

    10/24/2020
    A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?

    A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?
    Saulle I, Vanetti C, Goglia S, Vicentini C, Tombetti E, Garziano M, Clerici M, Biasin M., Free PMC Article

    09/26/2020
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