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    VSIR V-set immunoregulatory receptor [ Homo sapiens (human) ]

    Gene ID: 64115, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Expression and Prognostic Significance of LAG-3, TIGIT, VISTA, and IDO1 in Endometrial Serous Carcinoma.

    Expression and Prognostic Significance of LAG-3, TIGIT, VISTA, and IDO1 in Endometrial Serous Carcinoma.
    Chen H, Molberg K, Carrick K, Niu S, Rivera Colon G, Gwin K, Lewis C, Lea J, Panwar V, Zheng W, Castrillon DH, Lucas E.

    08/28/2024
    LRIG1 engages ligand VISTA and impairs tumor-specific CD8[+] T cell responses.

    LRIG1 engages ligand VISTA and impairs tumor-specific CD8(+) T cell responses.
    Ta HM, Roy D, Zhang K, Alban T, Juric I, Dong J, Parthasarathy PB, Patnaik S, Delaney E, Gilmour C, Zakeri A, Shukla N, Rupani A, Phoon YP, Liu C, Avril S, Gastman B, Chan T, Wang LL., Free PMC Article

    08/15/2024
    Aberrant expression of B7-H4 and B7-H5 contributes to the development of cutaneous squamous cell carcinoma.

    Aberrant expression of B7-H4 and B7-H5 contributes to the development of cutaneous squamous cell carcinoma.
    Chen L, Zhou B, Tang M, Yao Y, Zhao Y, Hu Y, Lin Y, Ji J, Jiao Q., Free PMC Article

    06/18/2024
    Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma.

    Unraveling the potential of CD8, CD68, and VISTA as diagnostic and prognostic markers in patients with pancreatic ductal adenocarcinoma.
    Rezagholizadeh F, Tajik F, Talebi M, Taha SR, Shariat Zadeh M, Farhangnia P, Hosseini HS, Nazari A, Mollazadeh Ghomi S, Kamrani Mousavi SM, Haeri Moghaddam N, Khorramdelazad H, Joghataei MT, Safari E., Free PMC Article

    02/21/2024
    PD-1H/VISTA mediates immune evasion in acute myeloid leukemia.

    PD-1H/VISTA mediates immune evasion in acute myeloid leukemia.
    Kim TK, Han X, Hu Q, Vandsemb EN, Fielder CM, Hong J, Kim KW, Mason EF, Plowman RS, Wang J, Wang Q, Zhang JP, Badri T, Sanmamed MF, Zheng L, Zhang T, Alawa J, Lee SW, Zeidan AM, Halene S, Pillai MM, Chandhok NS, Lu J, Xu ML, Gore SD, Chen L., Free PMC Article

    02/9/2024
    VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms.

    VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms.
    Zhang K, Zakeri A, Alban T, Dong J, Ta HM, Zalavadia AH, Branicky A, Zhao H, Juric I, Husich H, Parthasarathy PB, Rupani A, Drazba JA, Chakraborty AA, Ching-Cheng Huang S, Chan T, Avril S, Wang LL., Free PMC Article

    02/5/2024
    Dual silencing of tumor-intrinsic VISTA and CTLA-4 stimulates T-cell mediated immune responses and inhibits MCF7 breast cancer development.

    Dual silencing of tumor-intrinsic VISTA and CTLA-4 stimulates T-cell mediated immune responses and inhibits MCF7 breast cancer development.
    Hosseinkhani N, Hemmat N, Baghbani E, Baghbanzadeh A, Kazemi T, Mokhtarzadeh A, Jafarlou M, Amin Doustvandi M, Baradaran B.

    02/1/2024
    Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes.

    Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes.
    Vesely MD, Kidacki M, Gaule P, Gupta S, Chan NNN, Han X, Yeung JT, Chen L.

    12/26/2023
    Characterisation of the protein expression of the emerging immunotherapy targets VISTA, LAG-3 and PRAME in primary uveal melanoma: insights from a southern French patient cohort.

    Characterisation of the protein expression of the emerging immunotherapy targets VISTA, LAG-3 and PRAME in primary uveal melanoma: insights from a southern French patient cohort.
    Lamas NJ, Lassalle S, Martel A, Nahon-Estève S, Macocco A, Zahaf K, Lalvee S, Fayada J, Lespinet-Fabre V, Bordone O, Pedeutour F, Baillif S, Hofman P.

    11/30/2023
    VISTA blockade alleviates immunosuppression of MDSCs in oral squamous cell carcinoma.

    VISTA blockade alleviates immunosuppression of MDSCs in oral squamous cell carcinoma.
    Liu J, Lin WP, Xiao Y, Yang QC, Bushabu Fidele N, Yu HJ, Sun ZJ.

    11/30/2023
    VISTA Expression on Cancer-Associated Endothelium Selectively Prevents T-cell Extravasation.

    VISTA Expression on Cancer-Associated Endothelium Selectively Prevents T-cell Extravasation.
    Luk SJ, Schoppmeyer R, Ijsselsteijn ME, Somarakis A, Acem I, Remst DFG, Cox DT, van Bergen CAM, Briaire-de Bruijn I, Grönloh MLB, van der Meer WJ, Hawinkels LJAC, Koning RI, Bos E, Bovée JVMG, de Miranda NFCC, Szuhai K, van Buul JD, Falkenburg JHF, Heemskerk MHM.

    11/6/2023
    PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea.

    PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea.
    Díaz-García E, García-Sánchez A, Alfaro E, López-Fernández C, Mañas E, Cano-Pumarega I, López-Collazo E, García-Río F, Cubillos-Zapata C., Free PMC Article

    11/1/2023
    VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis.

    VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis.
    Kim SH, Adams TS, Hu Q, Shin HJ, Chae G, Lee SE, Sharma L, Kwon HK, Lee FY, Park HJ, Huh WJ, Manning E, Kaminski N, Sauler M, Chen L, Song JW, Kim TK, Kang MJ., Free PMC Article

    10/20/2023
    Expression of PD-L1 and VISTA in Intraductal Papillary Mucinous Neoplasm With Associated Invasive Carcinoma of the Pancreas.

    Expression of PD-L1 and VISTA in Intraductal Papillary Mucinous Neoplasm With Associated Invasive Carcinoma of the Pancreas.
    Mo S, Zou L, Hu Y, Chang X, Chen J.

    09/25/2023
    A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases.

    A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases.
    Nygaard V, Ree AH, Dagenborg VJ, Børresen-Dale AL, Edwin B, Fretland ÅA, Grzyb K, Haugen MH, Mælandsmo GM, Flatmark K., Free PMC Article

    08/10/2023
    Downregulated VISTA enhances Th17 differentiation and aggravates inflammation in patients with acute-on-chronic liver failure.

    Downregulated VISTA enhances Th17 differentiation and aggravates inflammation in patients with acute-on-chronic liver failure.
    Zhang Y, Zhang X, Han J, Guo Y, Yang F, Li F, Zhu H, Shen Z, Huang Y, Mao R, Zhang J.

    08/1/2023
    Comparison of PD-L1 and VISTA expression status in primary and recurrent/refractory tissue after (chemo)radiotherapy in head and neck cancer.

    Comparison of PD-L1 and VISTA expression status in primary and recurrent/refractory tissue after (chemo)radiotherapy in head and neck cancer.
    Şener GY, Sütcüoğlu O, Öğüt B, Güven DC, Kavuncuoğlu A, Özdemir N, Özet A, Aksoy S, Tezel YGG, Akyürek N, Yazıcı O.

    07/25/2023
    Immune-checkpoint protein VISTA in allergic, autoimmune disease and transplant rejection.

    Immune-checkpoint protein VISTA in allergic, autoimmune disease and transplant rejection.
    Zheng M, Zhang Z, Yu L, Wang Z, Dong Y, Tong A, Yang H., Free PMC Article

    07/13/2023
    Immune checkpoint receptor VISTA on immune cells is associated with expression of T-cell exhaustion marker TOX and worse prognosis in renal cell carcinoma with venous tumor thrombus.

    Immune checkpoint receptor VISTA on immune cells is associated with expression of T-cell exhaustion marker TOX and worse prognosis in renal cell carcinoma with venous tumor thrombus.
    Zapała Ł, Kunc M, Sharma S, Pęksa R, Popęda M, Biernat W, Radziszewski P., Free PMC Article

    07/7/2023
    [Correlation and clinical significance of VISTA expression and cervical squamous cell carcinoma].

    [Correlation and clinical significance of VISTA expression and cervical squamous cell carcinoma].
    Li L, Wang LL, Zhou JY.

    05/25/2023
    Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia.

    Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia.
    Mo J, Deng L, Peng K, Ouyang S, Ding W, Lou L, Lin Z, Zhu J, Li J, Zhang Q, Wang P, Wen Y, Chen X, Yue P, Lu JJ, Zhu K, Zheng Y, Wang Y, Zhang X., Free PMC Article

    03/6/2023
    Expression and clinical significance of VISTA and PD-L1 in adrenocortical carcinoma.

    Expression and clinical significance of VISTA and PD-L1 in adrenocortical carcinoma.
    Zhang Z, Li M, Wang J, Liu M, Chen H, Lou Y, Wang Y, Sun Q, Zhu D, Li P, Bi Y.

    06/11/2022
    Different clinical significance of novel B7 family checkpoints VISTA and HHLA2 in human lung adenocarcinoma.

    Different clinical significance of novel B7 family checkpoints VISTA and HHLA2 in human lung adenocarcinoma.
    Long L, Zhang L, Yang Y, Zhou Y, Chen H.

    05/7/2022
    Kidney VISTA prevents IFN-gamma/IL-9 axis-mediated tubulointerstitial fibrosis after acute glomerular injury.

    Kidney VISTA prevents IFN-γ/IL-9 axis-mediated tubulointerstitial fibrosis after acute glomerular injury.
    Kim MG, Yun D, Kang CL, Hong M, Hwang J, Moon KC, Jeong CW, Kwak C, Kim DK, Oh KH, Joo KW, Kim YS, Lee DS, Han SS., Free PMC Article

    02/19/2022
    Soluble B7-H5 Is a Novel Diagnostic, Severity, and Prognosis Marker in Acute Pancreatitis.

    Soluble B7-H5 Is a Novel Diagnostic, Severity, and Prognosis Marker in Acute Pancreatitis.
    Xu R, Gong J, Chen W, Jin Y, Huang J., Free PMC Article

    02/5/2022
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