| Correlations of PSGL-1 VNTR polymorphism with the susceptibility to severe HFMD associated with EV-71 and the immune status after infection. | Correlations of PSGL-1 VNTR polymorphism with the susceptibility to severe HFMD associated with EV-71 and the immune status after infection.
Wang X, Qian J, Mi Y, Li Y, Cao Y, Qiao K., Free PMC Article | 09/25/2024 |
| PSGL-1 decorated with sialyl Lewis[a/x] promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement. | PSGL-1 decorated with sialyl Lewis(a/x) promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement.
O'Dwyer M, Kirkham-McCarthy L, Cerreto M, Foà R, Natoni A., Free PMC Article | 01/30/2024 |
| PSGL-1 is an evolutionarily conserved antiviral restriction factor. | PSGL-1 is an evolutionarily conserved antiviral restriction factor.
Jiang C, Mei M, Liu Y, Hou M, Jiao J, Tan Y, Tan X., Free PMC Article | 01/3/2024 |
| PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea. | PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea.
Díaz-García E, García-Sánchez A, Alfaro E, López-Fernández C, Mañas E, Cano-Pumarega I, López-Collazo E, García-Río F, Cubillos-Zapata C., Free PMC Article | 11/1/2023 |
| PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated Macrophages. | PSGL-1 Blockade Induces Classical Activation of Human Tumor-associated Macrophages.
Kauffman K, Manfra D, Nowakowska D, Zafari M, Nguyen PA, Phennicie R, Vollmann EH, O'Nuallain B, Basinski S, Komoroski V, Rooney K, Culyba EK, Wahle J, Ries C, Brehm M, Sazinsky S, Feldman I, Novobrantseva TI., Free PMC Article | 10/28/2023 |
| The effects of SCARB2 and SELPLG gene polymorphisms on EV71 infection in hand, foot and mouth disease. | The effects of SCARB2 and SELPLG gene polymorphisms on EV71 infection in hand, foot and mouth disease.
Duan FY, Du ZQ, Wang Y, Luo L, Du LJ, Jiang H, Ma Y, Yang YL., Free PMC Article | 09/8/2023 |
| Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation. | Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation.
Goth CK, Mehta AY, McQuillan AM, Baker KJ, Hanes MS, Park SS, Stavenhagen K, Hjortø GM, Heimburg-Molinaro J, Chaikof EL, Rosenkilde MM, Cummings RD., Free PMC Article | 08/25/2023 |
| PSGL-1 attenuates early TCR signaling to suppress CD8[+] T cell progenitor differentiation and elicit terminal CD8[+] T cell exhaustion. | PSGL-1 attenuates early TCR signaling to suppress CD8(+) T cell progenitor differentiation and elicit terminal CD8(+) T cell exhaustion.
Hope JL, Otero DC, Bae EA, Stairiker CJ, Palete AB, Faso HA, Lin M, Henriquez ML, Roy S, Seo H, Lei X, Wang ES, Chow S, Tinoco R, Daniels GA, Yip K, Campos AR, Yin J, Adams PD, Rao A, Bradley LM., Free PMC Article | 06/7/2023 |
| Lnc-SELPLG-2:1 enhanced osteosarcoma oncogenesis via hsa-miR-10a-5p and the BTRC cascade. | Lnc-SELPLG-2:1 enhanced osteosarcoma oncogenesis via hsa-miR-10a-5p and the BTRC cascade.
Li S, Zeng M, Yang L, Tan J, Yang J, Guan H, Kuang M, Li J., Free PMC Article | 10/15/2022 |
| P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells. | P-selectin glycoprotein ligand-1 (PSGL-1/CD162) is incorporated into clinical HIV-1 isolates and can mediate virus capture and subsequent transfer to permissive cells.
Burnie J, Persaud AT, Thaya L, Liu Q, Miao H, Grabinsky S, Norouzi V, Lusso P, Tang VA, Guzzo C., Free PMC Article | 05/28/2022 |
| SELPLG Expression Was Potentially Correlated With Metastasis and Prognosis of Osteosarcoma. | SELPLG Expression Was Potentially Correlated With Metastasis and Prognosis of Osteosarcoma.
Wang B, Sun Y., Free PMC Article | 02/26/2022 |
| P-Selectin Glycoprotein Ligand-1 Deficiency Protects Against Aortic Aneurysm Formation Induced by DOCA Plus Salt. | P-Selectin Glycoprotein Ligand-1 Deficiency Protects Against Aortic Aneurysm Formation Induced by DOCA Plus Salt.
Wu X, Liu X, Yang H, Chen Q, Zhang N, Li Y, Du X, Liu X, Jiang X, Jiang Y, Zhou Z, Yang Z. | 02/26/2022 |
| Myeloid Mineralocorticoid Receptor Transcriptionally Regulates P-Selectin Glycoprotein Ligand-1 and Promotes Monocyte Trafficking and Atherosclerosis. | Myeloid Mineralocorticoid Receptor Transcriptionally Regulates P-Selectin Glycoprotein Ligand-1 and Promotes Monocyte Trafficking and Atherosclerosis.
Man JJ, Lu Q, Moss ME, Carvajal B, Baur W, Garza AE, Freeman R, Anastasiou M, Ngwenyama N, Adler GK, Alcaide P, Jaffe IZ., Free PMC Article | 11/27/2021 |
| P-selectin glycoprotein ligand 1 deficiency prevents development of acute pancreatitis by attenuating leukocyte infiltration. | P-selectin glycoprotein ligand 1 deficiency prevents development of acute pancreatitis by attenuating leukocyte infiltration.
Zhang X, Zhu M, Jiang XL, Liu X, Liu X, Liu P, Wu XX, Yang ZW, Qin T., Free PMC Article | 08/21/2021 |
| Circulating P-Selectin Glycoprotein Ligand 1 and P-Selectin Levels in Obstructive Sleep Apnea Patients. | Circulating P-Selectin Glycoprotein Ligand 1 and P-Selectin Levels in Obstructive Sleep Apnea Patients.
Horváth P, Lázár Z, Gálffy G, Puskás R, Kunos L, Losonczy G, Mészáros M, Tárnoki ÁD, Tárnoki DL, Bikov A., Free PMC Article | 06/5/2021 |
| Virion-incorporated host transmembrane proteins PSGL-1 and CD43 inhibit attachment of HIV-1 particles to target cells. Co-clustering of HIV-1 structural protein Gag with PSGL-1 and subsequent progeny virion release contribute to depletion of PSGL-1 from an infected cell surface. In addition, study reports a previously unidentified role for Gag in viral down-regulation of antiviral proteins. | Virion-incorporated PSGL-1 and CD43 inhibit both cell-free infection and transinfection of HIV-1 by preventing virus-cell binding.
Murakami T, Carmona N, Ono A., Free PMC Article | 07/25/2020 |
| VISTA is an acidic pH-selective ligand for PSGL-1 | VISTA is an acidic pH-selective ligand for PSGL-1.
Johnston RJ, Su LJ, Pinckney J, Critton D, Boyer E, Krishnakumar A, Corbett M, Rankin AL, Dibella R, Campbell L, Martin GH, Lemar H, Cayton T, Huang RY, Deng X, Nayeem A, Chen H, Ergel B, Rizzo JM, Yamniuk AP, Dutta S, Ngo J, Shorts AO, Ramakrishnan R, Kozhich A, Holloway J, Fang H, Wang YK, Yang Z, Thiam K, Rakestraw G, Rajpal A, Sheppard P, Quigley M, Bahjat KS, Korman AJ. | 11/23/2019 |
| PSGL-1 contributed to cytotoxic CD4 T cell homing to the culprit coronary artery and promoted plaque instability in ACS. | P-Selectin Glycoprotein Ligand-1 (PSGL-1) Expressing CD4 T Cells Contribute Plaque Instability in Acute Coronary Syndrome.
Kitamura K, Sato K, Sawabe M, Yoshida M, Hagiwara N. | 11/9/2019 |
| Consensus sequence analysis revealed enterovirus 71 with mutations at E145G and S241L and partial mutations at V146I of VP1, and a T to C substitution at nucleotide 494 of the 5'-UTR exhibited higher binding affinity for virus receptor, human P-selectin glycoprotein ligand-1 (hPSGL-1). | Mutations in VP1 and 5'-UTR affect enterovirus 71 virulence.
Chang CK, Wu SR, Chen YC, Lee KJ, Chung NH, Lu YJ, Yu SL, Liu CC, Chow YH., Free PMC Article | 10/19/2019 |
| PSGL-1 was identified as an HIV-1 restriction factor downregulated by HIV-1 Vpu, which binds to PSGL-1 and induces its ubiquitination and degradation through the ubiquitin ligase SCF(beta-TrCP2). | Proteomic profiling of HIV-1 infection of human CD4(+) T cells identifies PSGL-1 as an HIV restriction factor.
Liu Y, Fu Y, Wang Q, Li M, Zhou Z, Dabbagh D, Fu C, Zhang H, Li S, Zhang T, Gong J, Kong X, Zhai W, Su J, Sun J, Zhang Y, Yu XF, Shao Z, Zhou F, Wu Y, Tan X. | 06/29/2019 |
| PSGL-1 VNTR polymorphism may have limited contribution to the thrombotic tendency in patients with Behcet's disease. | The association between P selectin glycoprotein ligand 1 gene variable number of tandem repeats polymorphism and risk of thrombosis in Behçet's disease.
Cosan F, Oku B, Gedar Totuk OM, Abaci N, Ustek D, Diz Kucukkaya R, Gul A. | 06/1/2019 |
| PSGL-1 polymorphisms (rs7137098 and rs8179137) were significantly associated with severe EV71 infection (OR 1.46, 95% CI 1.1-1.96; and OR 1.47, 95% CI 1.07-2.03, respectively). | Polymorphisms in enterovirus 71 receptors associated with susceptibility and clinical severity.
Yen TY, Shih WL, Huang YC, Lee JT, Huang LM, Chang LY., Free PMC Article | 04/27/2019 |
| PI3K is a signal linker between L-selectin and PSGL-1 in IL-18 transcriptional activation at the promoter level. | PI3K Is a Linker Between L-selectin and PSGL-1 Signaling to IL-18 Transcriptional Activation at the Promoter Level.
Luo J. | 10/6/2018 |
| These data indicate that cardiac surgery influences the expression of CD162, CD166 and CD195 and that the intensity of the immune system response, displayed as the change in the CD162, CD166, CD195 expression, varies, depending on the surgical technique used. | Effects of conventional CPB and mini-CPB on neutrophils CD162, CD166 and CD195 expression.
Holmannova D, Kolackova M, Mandak J, Kunes P, Holubcova Z, Holubec T, Krejsek J. | 08/4/2018 |
| PSGL1 mediated leukocyte rolling and the inflammatory response in general.PSGL1 is a ligand for Siglec-5 and interacts with Siglec-5 ectodomain. | Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity.
Pepin M, Mezouar S, Pegon J, Muczynski V, Adam F, Bianchini EP, Bazaa A, Proulle V, Rupin A, Paysant J, Panicot-Dubois L, Christophe OD, Dubois C, Lenting PJ, Denis CV., Free PMC Article | 07/14/2018 |