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    SLC17A9 solute carrier family 17 member 9 [ Homo sapiens (human) ]

    Gene ID: 63910, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The HHEX-ABI2/SLC17A9 axis induces cancer stem cell-like properties and tumorigenesis in HCC.

    The HHEX-ABI2/SLC17A9 axis induces cancer stem cell-like properties and tumorigenesis in HCC.
    Li H, Liu J, Lai J, Su X, Wang X, Cao J, Mao S, Zhang T, Gu Q., Free PMC Article

    10/22/2024
    LINC01836 Promotes Colorectal Cancer Progression and Functions as ceRNA to Target SLC17A9 by Sponging miR-1226-3p.

    LINC01836 Promotes Colorectal Cancer Progression and Functions as ceRNA to Target SLC17A9 by Sponging miR-1226-3p.
    Xu Z, Yu Y, Ni H, Sun W, Kuang Y.

    03/12/2024
    Single-nucleotide polymorphisms of the SLC17A9 and P2RY12 genes are significantly associated with phantom tooth pain.

    Single-nucleotide polymorphisms of the SLC17A9 and P2RY12 genes are significantly associated with phantom tooth pain.
    Soeda M, Ohka S, Nishizawa D, Hasegawa J, Nakayama K, Ebata Y, Fukuda KI, Ikeda K., Free PMC Article

    04/16/2022
    [VNUT Is a Therapeutic Target for Type 2 Diabetes and NASH].

    [VNUT Is a Therapeutic Target for Type 2 Diabetes and NASH].
    Hasuzawa N, Tatsushima K, Tokubuchi R, Kabashima M, Nomura M.

    07/3/2021
    Transient Receptor Potential Vanilloid 4 Regulation of Adenosine Triphosphate Release by the Adenosine Triphosphate Transporter Vesicular Nucleotide Transporter, a Novel Therapeutic Target for Gastrointestinal Baroreception and Chronic Inflammation.

    Transient Receptor Potential Vanilloid 4 Regulation of Adenosine Triphosphate Release by the Adenosine Triphosphate Transporter Vesicular Nucleotide Transporter, a Novel Therapeutic Target for Gastrointestinal Baroreception and Chronic Inflammation.
    Mihara H, Boudaka A, Tominaga M, Sugiyama T., Free PMC Article

    08/13/2020
    High expression of SLC17A9 was associated with gastric cancer.

    High SLC17A9 expression correlates with poor survival in gastric carcinoma.
    Li J, Su T, Yang L, Deng L, Zhang C, He Y.

    05/30/2020
    our data suggested that SLC17A9 may play an important role in the progression of colorectal cancer

    High expression of SLC17A9 correlates with poor prognosis in colorectal cancer.
    Yang L, Chen Z, Xiong W, Ren H, Zhai E, Xu K, Yang H, Zhang Z, Ding L, He Y, Song X, Liu J.

    11/16/2019
    expression of TRPV4 and VNUT in normal human gastrointestinal cell derived cell lines

    Involvement of VNUT-exocytosis in transient receptor potential vanilloid 4-dependent ATP release from gastrointestinal epithelium.
    Mihara H, Uchida K, Koizumi S, Moriyama Y., Free PMC Article

    04/6/2019
    Data (including data from studies using knockout mice) suggest that VNUT/SLC17A9 localized in tertiary/secretory granules of neutrophils is responsible for vesicular ATP release and subsequent neutrophil migration/infiltration.

    Vesicular nucleotide transporter mediates ATP release and migration in neutrophils.
    Harada Y, Kato Y, Miyaji T, Omote H, Moriyama Y, Hiasa M., Free PMC Article

    01/12/2019
    Results identified SLC17A9 as another pathogenic gene for DSAP, which suggests a correlation between the aberrant vesicular nucleotide transporter and the pathogenesis of DSAP.

    Exome sequencing identifies SLC17A9 pathogenic gene in two Chinese pedigrees with disseminated superficial actinic porokeratosis.
    Cui H, Li L, Wang W, Shen J, Yue Z, Zheng X, Zuo X, Liang B, Gao M, Fan X, Yin X, Shen C, Yang C, Zhang C, Zhang X, Sheng Y, Gao J, Zhu Z, Lin D, Zhang A, Wang Z, Liu S, Sun L, Yang S, Cui Y, Zhang X.

    05/23/2015
    data suggest that SLC17A9 activity mediates lysosomal ATP accumulation and plays an important role in lysosomal physiology and cell viability.

    SLC17A9 protein functions as a lysosomal ATP transporter and regulates cell viability.
    Cao Q, Zhao K, Zhong XZ, Zou Y, Yu H, Huang P, Xu TL, Dong XP., Free PMC Article

    12/20/2014
    It is suggested that the functions of VNUT, in addition to P2 receptors may be a target for anti-inflammatory response in skin.

    Mechanism underlying ATP release in human epidermal keratinocytes.
    Inoue K, Komatsu R, Imura Y, Fujishita K, Shibata K, Moriyama Y, Koizumi S.

    06/21/2014
    These results suggest that SLC17A9 is the relevant nucleotide transporter responsible for the uptake of cytosolic nucleotides into mucin granules.

    Vesicular nucleotide transporter regulates the nucleotide content in airway epithelial mucin granules.
    Sesma JI, Kreda SM, Okada SF, van Heusden C, Moussa L, Jones LC, O'Neal WK, Togawa N, Hiasa M, Moriyama Y, Lazarowski ER., Free PMC Article

    07/13/2013
    the existence of an SLC17A9-dependent ATP-enriched vesicular pool in biliary epithelium that undergoes regulated exocytosis to initiate purinergic signaling.

    Regulation of purinergic signaling in biliary epithelial cells by exocytosis of SLC17A9-dependent ATP-enriched vesicles.
    Sathe MN, Woo K, Kresge C, Bugde A, Luby-Phelps K, Lewis MA, Feranchak AP., Free PMC Article

    01/28/2012
    analysis of involvement of SLC17A9-dependent vesicular exocytosis in the mechanism of ATP release during T cell activation

    Involvement of SLC17A9-dependent vesicular exocytosis in the mechanism of ATP release during T cell activation.
    Tokunaga A, Tsukimoto M, Harada H, Moriyama Y, Kojima S., Free PMC Article

    06/28/2010
    SLC17A9 protein acts as a vesicular nucleotide transporter (VNUT) and plays an essential role in vesicular storage of ATP in the ATP-secreting cells [SLC17A9]

    Identification of a vesicular nucleotide transporter.
    Sawada K, Echigo N, Juge N, Miyaji T, Otsuka M, Omote H, Yamamoto A, Moriyama Y., Free PMC Article

    01/21/2010
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