| Serum Brevican as a Biomarker of Cerebrovascular Disease in an Elderly Cognitively Impaired Cohort. | Serum Brevican as a Biomarker of Cerebrovascular Disease in an Elderly Cognitively Impaired Cohort.
Chia RSL, Minta K, Wu LY, Salai KHT, Chai YL, Hilal S, Venketasubramanian N, Chen CP, Chong JR, Lai MKP., Free PMC Article | 02/12/2024 |
| The Role of BEHAB/Brevican in the Tumor Microenvironment: Mediating Glioma Cell Invasion and Motility. | The Role of BEHAB/Brevican in the Tumor Microenvironment: Mediating Glioma Cell Invasion and Motility.
Giamanco KA, Matthews RT. | 10/24/2020 |
| The CNS-specific proteoglycan, brevican, and its ADAMTS4-cleaved fragment show differential serological levels in Alzheimer's disease, other types of dementia and non-demented controls: A cross-sectional study. | The CNS-specific proteoglycan, brevican, and its ADAMTS4-cleaved fragment show differential serological levels in Alzheimer's disease, other types of dementia and non-demented controls: A cross-sectional study.
Jonesco DS, Karsdal MA, Henriksen K., Free PMC Article | 08/29/2020 |
| Data indicate that median methylation levels of BCAN, HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis. | Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.
Faryna M, Konermann C, Aulmann S, Bermejo JL, Brugger M, Diederichs S, Rom J, Weichenhan D, Claus R, Rehli M, Schirmacher P, Sinn HP, Plass C, Gerhauser C. | 04/13/2013 |
| High Brevican is associated with the invasive phenotype of low-grade astrocytoma. | Brevican, neurocan, tenascin-C and versican are mainly responsible for the invasiveness of low-grade astrocytoma.
Varga I, Hutóczki G, Szemcsák CD, Zahuczky G, Tóth J, Adamecz Z, Kenyeres A, Bognár L, Hanzély Z, Klekner A. | 08/4/2012 |
| Observational study and meta-analysis of gene-disease association. (HuGE Navigator) | Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area.
Kähler AK, Djurovic S, Rimol LM, Brown AA, Athanasiu L, Jönsson EG, Hansen T, Gústafsson O, Hall H, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, St Clair D, Sigurdsson E, Petursson H, Rujescu D, Melle I, Werge T, Steen VM, Dale AM, Matthews RT, Agartz I, Andreassen OA. | 12/5/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Confirmation of genomewide association signals in Chinese Han population reveals risk loci for ischemic stroke.
Ding H, Xu Y, Bao X, Wang X, Cui G, Wang W, Hui R, Wang DW. | 12/2/2009 |
| The proteoglycan brevican binds to fibronectin after proteolytic cleavage and promotes glioma cell motility | The proteoglycan brevican binds to fibronectin after proteolytic cleavage and promotes glioma cell motility.
Hu B, Kong LL, Matthews RT, Viapiano MS., Free PMC Article | 01/21/2010 |
| These results demonstrate for the first time that ADAMTS-5 is capable of degrading brevican and is overexpressed in glioblastoma cells, and suggest that ADAMTS-5 may play a role in glioma cell invasion through the cleavage of brevican. | Human glioblastomas overexpress ADAMTS-5 that degrades brevican.
Nakada M, Miyamori H, Kita D, Takahashi T, Yamashita J, Sato H, Miura R, Yamaguchi Y, Okada Y. | 01/21/2010 |
| gene locus at chromosome 1q21-23. | Human BRAL1 and BCAN genes that belong to the link-module superfamily are tandemly arranged on chromosome 1q21-23.
Nomoto H, Oohashi T, Hirakawa S, Ueki Y, Ohtsuki H, Ninomiya Y. | 01/21/2010 |
| Authors describe the expression of BEHAB/brevican in human brain and characterize two novel glioma-specific isoforms which are generated by differential glycosylation and are absent from normal adult brain and other neuropathologies. | Novel tumor-specific isoforms of BEHAB/brevican identified in human malignant gliomas.
Viapiano MS, Bi WL, Piepmeier J, Hockfield S, Matthews RT. | 01/21/2010 |